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The map label for this gene is rimO [H]

Identifier: 158313057

GI number: 158313057

Start: 1440503

End: 1442290

Strand: Direct

Name: rimO [H]

Synonym: Franean1_1205

Alternate gene names: 158313057

Gene position: 1440503-1442290 (Clockwise)

Preceding gene: 158313056

Following gene: 158313058

Centisome position: 16.04

GC content: 75.0

Gene sequence:

>1788_bases
GTGTCTCCTCGTCCTGCACGCCGGGTAGCTCTCGTCACGCTCGGGTGTTCCCGTAACGAGGTGGATTCCGAGGAGCTTGC
CGCCCGCCTCGCCGCCGACGGCTGGGACCTGGTCGACGACGCCGCCGACGCGGACGCCGTCCTGGTCAACACCTGCGGTT
TCGTCGAGGCGGCGAAGAAGGACTCGATCGACGCCCTGCTCGCCGCCGACGCACTGCGCGGGCCCGGCGGCAACGGGCCC
GGTGACGGTGAGTCCGGCGATGACGGGCCGGGCGGCGGCGCGACCACCGGGCGGGCGACCGCGTCGGGCGGGCCGCGCGC
GGTCGTGGCCGTGGGCTGCATGGCCGAGCGGTACGGCCGGGAGCTCGCCGACACGCTGCCCGAGGCGGACGCCGTCCTCG
GCTTCGACGCATATCCGCGGATCTCGGCGCACCTCGACGCGGCGCTCGCCGGCTCGGCGCCGGCCTCGCACACCCCGCGT
GACCGGCGCACGCTGCTGCCGATCTCTCCGGTGGAGCGGGGCGACGCCTCCCGCGCGGCGCACTCGCCGCACATCCCTGG
TCACATCCAGCTCCCCGGTGGTGGACGTGTCCTTCCGTCGCCGGACGGCCGACCGGCGGCGAACAGCCGCCCGGCAACGG
ATCTGGCGGACCTGGCCGGCCTGGCGGAGCCGGCGGGGGAGGGCGCGGCCGGTACCGGCCGGCGGCGGCTCACCTCCAGC
CCGGTCGTGCCGCTGAAGCTGTCGAGCGGTTGCGACCGCCGTTGCGCCTTTTGCGCCATCCCGTCCTTCCGTGGCTCGCA
CGTGTCCCGCCGGCCGGAGGAGGTACTGGCCGAGGCCGAGTGGCTGGCTGGGCAGGGCGCCCGCGAGCTTGTCCTGGTCA
GCGAGAACTCGACGTCCTACGGCAAGGATCTCGGCGATCTGCGGGCGCTCGAGAAGCTGCTGCCCCTGCTGGCCGCCGTT
CCGGGGATTGTCCGTGTCCGCACTGTGTATCTCCAGCCGGCCGAGCTGCGGCCGTCCCTGCTCGAGGTGCTGCTGACGAC
GCCGGGCCTGGCGCCCTACCTTGACCTGTCGTTCCAGCACGCCAGCCCGGCGGTGCTGCGGCGGATGCGCCGGTTCGGCG
GCTCGACCGACTTCCTGGACCTGCTGCGGCGGGCCCGCGCGCTGCTCCCCGACCTGGGCGCCCGCTCGAACGTGATCGTC
GGCTTCCCCGGTGAGACCGACGAGGACGTCGACATCCTGGTGAATTTTCTCGAGCGCGCCGACCTCGACGCTGTCGGGGT
GTTCGGCTACTCCGACGAGGAGGGGACGGAGGCCGCCGGGATGGCGGGCCACGTCGACCCCGAGGAGATCGAGAGCCGGC
GGGCCGAGGTCACCGACCTCGTCGAGCAGCTCACCGCAGCCCGCGCCGAGCGCCGCATCGGCACGACCGTCGAGGTGCTC
GTCGAGGAGGTGGCCGGCGGTCTCGGGTACGGCTGCGCCGGGCACCAGCAGGCCGACGCCGACGGCTCCTGCACGGTCCG
CCTGCCCGCGGGCGGGCCACCGGGCGGGGTGTCCGTCGGGGACCTCGTCGAGGCCCGGGTCGTGGCGGCCGAGGGCGTCG
ACCTGATCGCGGAGTTCACCGGCGTGCTCGACCGTGCCGGCGCCGGGCTGGCCAGCGCTGGGTCAGCCGGTGCCGGGTCG
GTCGGTGCCGGGTCGGTCGGTTCGGCCGGGGCGGGTTCCGTGCTGCCGCCGATCCCGGACGGGGTCGGCCCGATGGACGC
GGTGGGCCACCCTTCGGGCGTGGCGTGA

Upstream 100 bases:

>100_bases
GCTGACGTCGGGCTTGGCGGGCTGGCCCTCGGCTCGGGTCGACCACGCCGGGCCGGGGCCGTCGGCGTGTTGTCCGCGGG
CGCCCCGGTAGCCTGAGTCC

Downstream 100 bases:

>100_bases
CCGGCACCGGCGACCTGGTGGCGCCGAAGCCGCCGGTCCTCAACATCGCGAACATCCTGACGATCATCCGGCTGGCCCTG
GTGCCGGTCTTTGTGGCCTT

Product: RNA modification protein

Products: NA

Alternate protein names: S12 MTTase; S12 methylthiotransferase; Ribosome maturation factor RimO [H]

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MSPRPARRVALVTLGCSRNEVDSEELAARLAADGWDLVDDAADADAVLVNTCGFVEAAKKDSIDALLAADALRGPGGNGP
GDGESGDDGPGGGATTGRATASGGPRAVVAVGCMAERYGRELADTLPEADAVLGFDAYPRISAHLDAALAGSAPASHTPR
DRRTLLPISPVERGDASRAAHSPHIPGHIQLPGGGRVLPSPDGRPAANSRPATDLADLAGLAEPAGEGAAGTGRRRLTSS
PVVPLKLSSGCDRRCAFCAIPSFRGSHVSRRPEEVLAEAEWLAGQGARELVLVSENSTSYGKDLGDLRALEKLLPLLAAV
PGIVRVRTVYLQPAELRPSLLEVLLTTPGLAPYLDLSFQHASPAVLRRMRRFGGSTDFLDLLRRARALLPDLGARSNVIV
GFPGETDEDVDILVNFLERADLDAVGVFGYSDEEGTEAAGMAGHVDPEEIESRRAEVTDLVEQLTAARAERRIGTTVEVL
VEEVAGGLGYGCAGHQQADADGSCTVRLPAGGPPGGVSVGDLVEARVVAAEGVDLIAEFTGVLDRAGAGLASAGSAGAGS
VGAGSVGSAGAGSVLPPIPDGVGPMDAVGHPSGVA

Sequences:

>Translated_595_residues
MSPRPARRVALVTLGCSRNEVDSEELAARLAADGWDLVDDAADADAVLVNTCGFVEAAKKDSIDALLAADALRGPGGNGP
GDGESGDDGPGGGATTGRATASGGPRAVVAVGCMAERYGRELADTLPEADAVLGFDAYPRISAHLDAALAGSAPASHTPR
DRRTLLPISPVERGDASRAAHSPHIPGHIQLPGGGRVLPSPDGRPAANSRPATDLADLAGLAEPAGEGAAGTGRRRLTSS
PVVPLKLSSGCDRRCAFCAIPSFRGSHVSRRPEEVLAEAEWLAGQGARELVLVSENSTSYGKDLGDLRALEKLLPLLAAV
PGIVRVRTVYLQPAELRPSLLEVLLTTPGLAPYLDLSFQHASPAVLRRMRRFGGSTDFLDLLRRARALLPDLGARSNVIV
GFPGETDEDVDILVNFLERADLDAVGVFGYSDEEGTEAAGMAGHVDPEEIESRRAEVTDLVEQLTAARAERRIGTTVEVL
VEEVAGGLGYGCAGHQQADADGSCTVRLPAGGPPGGVSVGDLVEARVVAAEGVDLIAEFTGVLDRAGAGLASAGSAGAGS
VGAGSVGSAGAGSVLPPIPDGVGPMDAVGHPSGVA
>Mature_594_residues
SPRPARRVALVTLGCSRNEVDSEELAARLAADGWDLVDDAADADAVLVNTCGFVEAAKKDSIDALLAADALRGPGGNGPG
DGESGDDGPGGGATTGRATASGGPRAVVAVGCMAERYGRELADTLPEADAVLGFDAYPRISAHLDAALAGSAPASHTPRD
RRTLLPISPVERGDASRAAHSPHIPGHIQLPGGGRVLPSPDGRPAANSRPATDLADLAGLAEPAGEGAAGTGRRRLTSSP
VVPLKLSSGCDRRCAFCAIPSFRGSHVSRRPEEVLAEAEWLAGQGARELVLVSENSTSYGKDLGDLRALEKLLPLLAAVP
GIVRVRTVYLQPAELRPSLLEVLLTTPGLAPYLDLSFQHASPAVLRRMRRFGGSTDFLDLLRRARALLPDLGARSNVIVG
FPGETDEDVDILVNFLERADLDAVGVFGYSDEEGTEAAGMAGHVDPEEIESRRAEVTDLVEQLTAARAERRIGTTVEVLV
EEVAGGLGYGCAGHQQADADGSCTVRLPAGGPPGGVSVGDLVEARVVAAEGVDLIAEFTGVLDRAGAGLASAGSAGAGSV
GAGSVGSAGAGSVLPPIPDGVGPMDAVGHPSGVA

Specific function: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 [H]

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI28872782, Length=333, Percent_Identity=27.027027027027, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI28872784, Length=333, Percent_Identity=27.027027027027, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI93277076, Length=361, Percent_Identity=24.6537396121884, Blast_Score=90, Evalue=7e-18,
Organism=Escherichia coli, GI1787057, Length=314, Percent_Identity=34.7133757961783, Blast_Score=169, Evalue=7e-43,
Organism=Escherichia coli, GI1786882, Length=271, Percent_Identity=32.4723247232472, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71996771, Length=336, Percent_Identity=25.8928571428571, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17553146, Length=274, Percent_Identity=24.8175182481752, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356207, Length=329, Percent_Identity=27.0516717325228, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19922432, Length=308, Percent_Identity=25.974025974026, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR007197
- InterPro:   IPR005840 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 60597; Mature: 60466

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRPARRVALVTLGCSRNEVDSEELAARLAADGWDLVDDAADADAVLVNTCGFVEAAKK
CCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCEEEEECCCHHHHHHC
DSIDALLAADALRGPGGNGPGDGESGDDGPGGGATTGRATASGGPRAVVAVGCMAERYGR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
ELADTLPEADAVLGFDAYPRISAHLDAALAGSAPASHTPRDRRTLLPISPVERGDASRAA
HHHHHCCCCHHEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCHHCC
HSPHIPGHIQLPGGGRVLPSPDGRPAANSRPATDLADLAGLAEPAGEGAAGTGRRRLTSS
CCCCCCCEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PVVPLKLSSGCDRRCAFCAIPSFRGSHVSRRPEEVLAEAEWLAGQGARELVLVSENSTSY
CCEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCH
GKDLGDLRALEKLLPLLAAVPGIVRVRTVYLQPAELRPSLLEVLLTTPGLAPYLDLSFQH
HCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHCHHHHHHHHHCCCCCHHHCCCCCC
ASPAVLRRMRRFGGSTDFLDLLRRARALLPDLGARSNVIVGFPGETDEDVDILVNFLERA
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHC
DLDAVGVFGYSDEEGTEAAGMAGHVDPEEIESRRAEVTDLVEQLTAARAERRIGTTVEVL
CCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VEEVAGGLGYGCAGHQQADADGSCTVRLPAGGPPGGVSVGDLVEARVVAAEGVDLIAEFT
HHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
GVLDRAGAGLASAGSAGAGSVGAGSVGSAGAGSVLPPIPDGVGPMDAVGHPSGVA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
SPRPARRVALVTLGCSRNEVDSEELAARLAADGWDLVDDAADADAVLVNTCGFVEAAKK
CCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCEEEEECCCHHHHHHC
DSIDALLAADALRGPGGNGPGDGESGDDGPGGGATTGRATASGGPRAVVAVGCMAERYGR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
ELADTLPEADAVLGFDAYPRISAHLDAALAGSAPASHTPRDRRTLLPISPVERGDASRAA
HHHHHCCCCHHEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCHHCC
HSPHIPGHIQLPGGGRVLPSPDGRPAANSRPATDLADLAGLAEPAGEGAAGTGRRRLTSS
CCCCCCCEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PVVPLKLSSGCDRRCAFCAIPSFRGSHVSRRPEEVLAEAEWLAGQGARELVLVSENSTSY
CCEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCH
GKDLGDLRALEKLLPLLAAVPGIVRVRTVYLQPAELRPSLLEVLLTTPGLAPYLDLSFQH
HCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHCHHHHHHHHHCCCCCHHHCCCCCC
ASPAVLRRMRRFGGSTDFLDLLRRARALLPDLGARSNVIVGFPGETDEDVDILVNFLERA
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHC
DLDAVGVFGYSDEEGTEAAGMAGHVDPEEIESRRAEVTDLVEQLTAARAERRIGTTVEVL
CCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VEEVAGGLGYGCAGHQQADADGSCTVRLPAGGPPGGVSVGDLVEARVVAAEGVDLIAEFT
HHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
GVLDRAGAGLASAGSAGAGSVGAGSVGSAGAGSVLPPIPDGVGPMDAVGHPSGVA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA