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The map label for this gene is pqqL [C]

Identifier: 158313042

GI number: 158313042

Start: 1415793

End: 1417226

Strand: Direct

Name: pqqL [C]

Synonym: Franean1_1190

Alternate gene names: 158313042

Gene position: 1415793-1417226 (Clockwise)

Preceding gene: 158313041

Following gene: 158313043

Centisome position: 15.76

GC content: 73.08

Gene sequence:

>1434_bases
GTGACGGAGACGGATCTGTCCACCTCGGACGACCGCACCTCGGACGGTCGCACCTCGAACGACCGCACCCCGGGCCTGGC
CGGGCCGGAGCACGCCTCCGGCCCGCGCCCGGCCCGGGTGGCCGAGCTTCTCGCGGCGGGTCCCGGTTCCGAGGTCCTGC
TCGCCGGGGCCGTGCGCCGCACGGTGCTGCCGGGCGGCCTGCGGGTCGTCACGGAGAAGGTCCCCGGGGTCCGGTCGGTG
GCGATCGGGATCTGGGTGGGCGTCGGCTCGCGGGACGAGACGCCGCTCACCGGTGGCTGCTCGCACTACCTGGAGCACCT
GCTGTTCAAGGGCACCCCGAGCCGGGACGCCCTGTCGATCAGCGCCTCCATCGAGGCCGTCGGCGGTGATCTCAACGCCT
TCACCGCCAAGGAGTACACCTGCTACTACGCGCGGGTGCTCGACGTGGACATGGACCTGGCCATCGACGTCGTCTGTGAC
ATGGTCGCCAACTCGCTGGTGACCGCGGACGACGTCGAGGCCGAGCGGGGCGTGATCCTCGAGGAGATCGCCATGCACGA
GGACGACCCCGGCGACGTCGTGCACGACGTCTTCGCCGACGCCGTCCTCGGCTCCTCCGTCCTGGGGCGACCGGTGCTCG
GCACGGTCGACACCATCGAGGCGCTCGGCCGGGAGACGGTCTTCGACTACTACCGCGAGCGGTACGCCCCGCCCGCGCTG
GTCGTCTCGATCGCCGGCAACATCGAGCACGACCACGCCCTGGACCGGGTGGTGGCCGCGTTCGCCGACCGGCTCACCGG
GCCCGCCCGGCACCAGGAGGTGCGCCGCGGCGAGTACCCGTTCCCGCCGCCGCCGGGCATCGTCGTCACCAACCGGCCGA
CCGAGCAGGCCCACGTGGTGCTCGGCACGGCCGGCCTGTCCCGGCACGACCCGCGCCGGTACGCGCTCGGCGTGCTGTCG
ACGGCCCTCGGTGGCGGGATGAGCTCGCGGCTGTTCCAGGAGGTGCGGGAGAAGCGCGGGCTGGCCTACTCCGTGTACTC
CTTCGACAACCAGTTCGCCGACGCCGGGCTGTTCGGCGTCTACGCGGGCTGTACCCCGGGGCGCGCCGACGAGGTGCTGG
AGATCTGCCGCGAGCAGGTGCACCGGATCGCCGAGCACGGCATCACCGCGGAGGAGCTCGAGCGGGCCCGCGGCCAGAAC
CGCGGCGGCCTGGTGCTCAACCTGGAGGACACCGGGTCGCGGATGAGCCGGCTCGGCAAGAGCGAGCTCGTCCACGGCGA
GCTGCTCTCGGTCGACGAGGTGCTCGCCCGGGTCGAGGCCGTCACACTCGACGACGTGCGGGCCGTCGCCGGCGAGCTGG
TCGACCAGCCGTGGGCGCTCGGCGTCATCGGCCCGTTCGAGGACCACGACTTCAGCGCGGCCGTAGCGCGGTGA

Upstream 100 bases:

>100_bases
CAGGTGGAGATCACCGAGATCGACGCCCGCGGCAAGATCAGCCTCGCGCCGGGCGCGGAGTCCATCGACACCGTAAGCGC
CGGATCCTGACAGGAGCGCA

Downstream 100 bases:

>100_bases
CCCGCGCGGCCGCTGGCGGTACCGGACACGTGGAGGGCACGGGATGATCGGCGTCGGGGTGCTCGGAGCCCGTGGCCGGA
TGGGCACGACCGTCTGCGAC

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MTETDLSTSDDRTSDGRTSNDRTPGLAGPEHASGPRPARVAELLAAGPGSEVLLAGAVRRTVLPGGLRVVTEKVPGVRSV
AIGIWVGVGSRDETPLTGGCSHYLEHLLFKGTPSRDALSISASIEAVGGDLNAFTAKEYTCYYARVLDVDMDLAIDVVCD
MVANSLVTADDVEAERGVILEEIAMHEDDPGDVVHDVFADAVLGSSVLGRPVLGTVDTIEALGRETVFDYYRERYAPPAL
VVSIAGNIEHDHALDRVVAAFADRLTGPARHQEVRRGEYPFPPPPGIVVTNRPTEQAHVVLGTAGLSRHDPRRYALGVLS
TALGGGMSSRLFQEVREKRGLAYSVYSFDNQFADAGLFGVYAGCTPGRADEVLEICREQVHRIAEHGITAEELERARGQN
RGGLVLNLEDTGSRMSRLGKSELVHGELLSVDEVLARVEAVTLDDVRAVAGELVDQPWALGVIGPFEDHDFSAAVAR

Sequences:

>Translated_477_residues
MTETDLSTSDDRTSDGRTSNDRTPGLAGPEHASGPRPARVAELLAAGPGSEVLLAGAVRRTVLPGGLRVVTEKVPGVRSV
AIGIWVGVGSRDETPLTGGCSHYLEHLLFKGTPSRDALSISASIEAVGGDLNAFTAKEYTCYYARVLDVDMDLAIDVVCD
MVANSLVTADDVEAERGVILEEIAMHEDDPGDVVHDVFADAVLGSSVLGRPVLGTVDTIEALGRETVFDYYRERYAPPAL
VVSIAGNIEHDHALDRVVAAFADRLTGPARHQEVRRGEYPFPPPPGIVVTNRPTEQAHVVLGTAGLSRHDPRRYALGVLS
TALGGGMSSRLFQEVREKRGLAYSVYSFDNQFADAGLFGVYAGCTPGRADEVLEICREQVHRIAEHGITAEELERARGQN
RGGLVLNLEDTGSRMSRLGKSELVHGELLSVDEVLARVEAVTLDDVRAVAGELVDQPWALGVIGPFEDHDFSAAVAR
>Mature_476_residues
TETDLSTSDDRTSDGRTSNDRTPGLAGPEHASGPRPARVAELLAAGPGSEVLLAGAVRRTVLPGGLRVVTEKVPGVRSVA
IGIWVGVGSRDETPLTGGCSHYLEHLLFKGTPSRDALSISASIEAVGGDLNAFTAKEYTCYYARVLDVDMDLAIDVVCDM
VANSLVTADDVEAERGVILEEIAMHEDDPGDVVHDVFADAVLGSSVLGRPVLGTVDTIEALGRETVFDYYRERYAPPALV
VSIAGNIEHDHALDRVVAAFADRLTGPARHQEVRRGEYPFPPPPGIVVTNRPTEQAHVVLGTAGLSRHDPRRYALGVLST
ALGGGMSSRLFQEVREKRGLAYSVYSFDNQFADAGLFGVYAGCTPGRADEVLEICREQVHRIAEHGITAEELERARGQNR
GGLVLNLEDTGSRMSRLGKSELVHGELLSVDEVLARVEAVTLDDVRAVAGELVDQPWALGVIGPFEDHDFSAAVAR

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=432, Percent_Identity=30.0925925925926, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI46593007, Length=437, Percent_Identity=28.604118993135, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI24308013, Length=474, Percent_Identity=23.4177215189873, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI50592988, Length=420, Percent_Identity=22.1428571428571, Blast_Score=77, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=400, Percent_Identity=27.25, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17553678, Length=431, Percent_Identity=26.2180974477958, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17510601, Length=432, Percent_Identity=24.0740740740741, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323192, Length=430, Percent_Identity=29.5348837209302, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6321813, Length=411, Percent_Identity=27.007299270073, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6319426, Length=447, Percent_Identity=22.1476510067114, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357875, Length=434, Percent_Identity=27.1889400921659, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24646943, Length=434, Percent_Identity=27.1889400921659, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI19921772, Length=495, Percent_Identity=25.6565656565657, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 51031; Mature: 50900

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETDLSTSDDRTSDGRTSNDRTPGLAGPEHASGPRPARVAELLAAGPGSEVLLAGAVRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
TVLPGGLRVVTEKVPGVRSVAIGIWVGVGSRDETPLTGGCSHYLEHLLFKGTPSRDALSI
HHCCCCCEEHHHHCCCHHEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEE
SASIEAVGGDLNAFTAKEYTCYYARVLDVDMDLAIDVVCDMVANSLVTADDVEAERGVIL
EEEHEECCCCCCCEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
EEIAMHEDDPGDVVHDVFADAVLGSSVLGRPVLGTVDTIEALGRETVFDYYRERYAPPAL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
VVSIAGNIEHDHALDRVVAAFADRLTGPARHQEVRRGEYPFPPPPGIVVTNRPTEQAHVV
EEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEE
LGTAGLSRHDPRRYALGVLSTALGGGMSSRLFQEVREKRGLAYSVYSFDNQFADAGLFGV
EEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCHHEE
YAGCTPGRADEVLEICREQVHRIAEHGITAEELERARGQNRGGLVLNLEDTGSRMSRLGK
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHCCH
SELVHGELLSVDEVLARVEAVTLDDVRAVAGELVDQPWALGVIGPFEDHDFSAAVAR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHCC
>Mature Secondary Structure 
TETDLSTSDDRTSDGRTSNDRTPGLAGPEHASGPRPARVAELLAAGPGSEVLLAGAVRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
TVLPGGLRVVTEKVPGVRSVAIGIWVGVGSRDETPLTGGCSHYLEHLLFKGTPSRDALSI
HHCCCCCEEHHHHCCCHHEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEE
SASIEAVGGDLNAFTAKEYTCYYARVLDVDMDLAIDVVCDMVANSLVTADDVEAERGVIL
EEEHEECCCCCCCEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
EEIAMHEDDPGDVVHDVFADAVLGSSVLGRPVLGTVDTIEALGRETVFDYYRERYAPPAL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
VVSIAGNIEHDHALDRVVAAFADRLTGPARHQEVRRGEYPFPPPPGIVVTNRPTEQAHVV
EEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEE
LGTAGLSRHDPRRYALGVLSTALGGGMSSRLFQEVREKRGLAYSVYSFDNQFADAGLFGV
EEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCHHEE
YAGCTPGRADEVLEICREQVHRIAEHGITAEELERARGQNRGGLVLNLEDTGSRMSRLGK
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHCCH
SELVHGELLSVDEVLARVEAVTLDDVRAVAGELVDQPWALGVIGPFEDHDFSAAVAR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]