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The map label for this gene is etfA [H]

Identifier: 158312929

GI number: 158312929

Start: 1272284

End: 1273246

Strand: Direct

Name: etfA [H]

Synonym: Franean1_1075

Alternate gene names: 158312929

Gene position: 1272284-1273246 (Clockwise)

Preceding gene: 158312928

Following gene: 158312930

Centisome position: 14.16

GC content: 70.51

Gene sequence:

>963_bases
ATGGCTGAAGTTCTTGTACTCGTCGAGCACAGCGATGGCGAGCCGAAGAAGGTCACGGCCGAGCTGCTGACGCTGGCCCG
CACGATCGGCGAGCCGTCGGCGGTGTTCCTCGGCGGCCCGGGCAGCTACGCCAAGGCGAAGGAGTACCTGGCCCAGTACG
GCGCGGCCAAGGTCTACCTGGTCGAGTCCGAAGACGTCGCCGACTACATCGGGGCGCCGGCGGCCGAGGTCCTGTCGAAG
CTGGTCGCGGACGTCTCGCCCGTGGCGGTCCTGGCCGCGGCCACGCCGGACTCCCGTGAGGTCGCGGCCCGCACGGCGGC
CCGCACGGATTCCGGCCTGATCTGGGACGCCACCGCGCTCACCTCCGACCTGACGGCCACCCAGGGCATCTTCGGCGGTT
CGACGATCGTCAACTCGAAGGTCACCAAGGGCACCCCGATCGTCGTCGTCCGGCCGAACTCGACCGCACCCGAGGCCGCG
CCGACGACCCCGGTGGAGACCCCGGTCGACATCGCGATCTCCGACGCCGCGAAGGGCGCGAAGATCGTGGACCGCGTCGT
CGAGGCGAAGTCCGGCCGTCCGGACCTCACCGAGGCCCAGATCGTCGTCTCCGGCGGCCGTGGCCTGGGTGCCGCCGAGC
ACTTCGCGCTGGTCGAGAAGCTGGCCGACACGCTCGGCGCGGCCGTCGGCGCCTCGCGCGCCGCGACCGACGCCGGCTGG
TACCCGCACCAGCACCAGGTCGGCCAGACCGGTAAGACGGTGTCGCCCCAGCTGTACATCGCGGTCGGGATCTCCGGCGC
CATCCAGCACCGGGCCGGCATGCAGACCTCGAAGACGATCGTGGCGGTCAACAAGGACCCCGAGGCCCCGATCTTCGAGT
TCGCGGACTACGGACTGGTCGGTGACCTGTTCAACGTCGTCCCGCAGCTCACCGAGGAGATCCAGAAGCACAAGGCCGGC
TGA

Upstream 100 bases:

>100_bases
CGCGCCAGAGCGGCACCATCGTCAAGGACGAGGGCGACGGCGGCGCGAAGGTCGCTGCGTTCCTCGCGGCCCAGAAGCTC
ATCTGAGGGGTTGTTGTTCG

Downstream 100 bases:

>100_bases
CCAGCCGAGCCGCTCCATCCGGGACGGCCCGCGACCGGGCCGTCCCGACCGGGCGCAGGACGGCCGGGTGCGTTCCCTCC
CTTCCGGTGGGGCCGCACCC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MAEVLVLVEHSDGEPKKVTAELLTLARTIGEPSAVFLGGPGSYAKAKEYLAQYGAAKVYLVESEDVADYIGAPAAEVLSK
LVADVSPVAVLAAATPDSREVAARTAARTDSGLIWDATALTSDLTATQGIFGGSTIVNSKVTKGTPIVVVRPNSTAPEAA
PTTPVETPVDIAISDAAKGAKIVDRVVEAKSGRPDLTEAQIVVSGGRGLGAAEHFALVEKLADTLGAAVGASRAATDAGW
YPHQHQVGQTGKTVSPQLYIAVGISGAIQHRAGMQTSKTIVAVNKDPEAPIFEFADYGLVGDLFNVVPQLTEEIQKHKAG

Sequences:

>Translated_320_residues
MAEVLVLVEHSDGEPKKVTAELLTLARTIGEPSAVFLGGPGSYAKAKEYLAQYGAAKVYLVESEDVADYIGAPAAEVLSK
LVADVSPVAVLAAATPDSREVAARTAARTDSGLIWDATALTSDLTATQGIFGGSTIVNSKVTKGTPIVVVRPNSTAPEAA
PTTPVETPVDIAISDAAKGAKIVDRVVEAKSGRPDLTEAQIVVSGGRGLGAAEHFALVEKLADTLGAAVGASRAATDAGW
YPHQHQVGQTGKTVSPQLYIAVGISGAIQHRAGMQTSKTIVAVNKDPEAPIFEFADYGLVGDLFNVVPQLTEEIQKHKAG
>Mature_319_residues
AEVLVLVEHSDGEPKKVTAELLTLARTIGEPSAVFLGGPGSYAKAKEYLAQYGAAKVYLVESEDVADYIGAPAAEVLSKL
VADVSPVAVLAAATPDSREVAARTAARTDSGLIWDATALTSDLTATQGIFGGSTIVNSKVTKGTPIVVVRPNSTAPEAAP
TTPVETPVDIAISDAAKGAKIVDRVVEAKSGRPDLTEAQIVVSGGRGLGAAEHFALVEKLADTLGAAVGASRAATDAGWY
PHQHQVGQTGKTVSPQLYIAVGISGAIQHRAGMQTSKTIVAVNKDPEAPIFEFADYGLVGDLFNVVPQLTEEIQKHKAG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=326, Percent_Identity=40.7975460122699, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI189181759, Length=238, Percent_Identity=46.6386554621849, Blast_Score=196, Evalue=3e-50,
Organism=Escherichia coli, GI1787990, Length=272, Percent_Identity=34.1911764705882, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786226, Length=227, Percent_Identity=35.6828193832599, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082157, Length=123, Percent_Identity=38.2113821138211, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=320, Percent_Identity=38.125, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6325261, Length=224, Percent_Identity=41.9642857142857, Blast_Score=166, Evalue=4e-42,
Organism=Drosophila melanogaster, GI17136898, Length=315, Percent_Identity=40.3174603174603, Blast_Score=195, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24652801, Length=315, Percent_Identity=40.3174603174603, Blast_Score=195, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33002; Mature: 32870

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLVLVEHSDGEPKKVTAELLTLARTIGEPSAVFLGGPGSYAKAKEYLAQYGAAKVYL
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEE
VESEDVADYIGAPAAEVLSKLVADVSPVAVLAAATPDSREVAARTAARTDSGLIWDATAL
EECCCHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEHHHH
TSDLTATQGIFGGSTIVNSKVTKGTPIVVVRPNSTAPEAAPTTPVETPVDIAISDAAKGA
HHHHHHHCCCCCCCCEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCH
KIVDRVVEAKSGRPDLTEAQIVVSGGRGLGAAEHFALVEKLADTLGAAVGASRAATDAGW
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YPHQHQVGQTGKTVSPQLYIAVGISGAIQHRAGMQTSKTIVAVNKDPEAPIFEFADYGLV
CCCCCCCCCCCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCCHH
GDLFNVVPQLTEEIQKHKAG
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEVLVLVEHSDGEPKKVTAELLTLARTIGEPSAVFLGGPGSYAKAKEYLAQYGAAKVYL
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEE
VESEDVADYIGAPAAEVLSKLVADVSPVAVLAAATPDSREVAARTAARTDSGLIWDATAL
EECCCHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEHHHH
TSDLTATQGIFGGSTIVNSKVTKGTPIVVVRPNSTAPEAAPTTPVETPVDIAISDAAKGA
HHHHHHHCCCCCCCCEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCH
KIVDRVVEAKSGRPDLTEAQIVVSGGRGLGAAEHFALVEKLADTLGAAVGASRAATDAGW
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YPHQHQVGQTGKTVSPQLYIAVGISGAIQHRAGMQTSKTIVAVNKDPEAPIFEFADYGLV
CCCCCCCCCCCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHCCCHH
GDLFNVVPQLTEEIQKHKAG
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]