BacMap

Definition	Frankia sp. EAN1pec chromosome, complete genome.
Accession	NC_009921
Length	8,982,042

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The map label for this gene is fadB1 [H]

Identifier: 158312925

GI number: 158312925

Start: 1267130

End: 1267906

Strand: Direct

Name: fadB1 [H]

Synonym: Franean1_1071

Alternate gene names: 158312925

Gene position: 1267130-1267906 (Clockwise)

Preceding gene: 158312923

Following gene: 158312928

Centisome position: 14.11

GC content: 74.0

Gene sequence:

>777_bases
ATGGCGGTCGTGCGGCTCGAGGTCTCCGACGGTGTCGGGACGATCAGGCTGGACCGGCCGCCGATGAACGCGCTCAACGC
GGCGCTTGCCGCTGAGCTGCGCGCCGCCGCCCTCGAGGCCACCGCCCGGGCGGACGTCCGGGCCGTTGTCGTCTACGGCG
GCGAGAAGGTGTTCGCCGCCGGGGCGGACATCAAGGAGATGGCGGGGCTGGACGTCGCCGGCATCACCGGCTGGGTCCGC
GATCTGGCCGCGGCCTTCGACCTGGTGGCGCGTATCCCGAAGCCGGTCGTCGCGGCCGTCACGGGCTATGCCCTCGGCGG
CGGCCTGGAGCTCGCGCTGTGTGCCGACTTCCGGGTCTTCGCCGAGAACGCGAAGGTCGGGCTGCCCGAGATCACCCTCG
GTGTGATCCCGGGCGCCGGTGGCACGCAGCGCCTGCCGCGGCTCGTCGGGCCGGCCCGGGCCAAGGATCTCGTCTTCAGC
GGCCGGCAGGTGCGGGCCGCCGAGGCGGAGGCGATCGGGCTGGCCGACAAGGTCGTCCCGGCCGATGAGGTGCACGCCGA
GGCCCTGCGGATGGCGGGTCGCTTCGTCACGGGGCCCGCCCTGGCACTGGCCGCGGCGAAGCAGGCGATCGACGACGGCG
GCGACCTCGCGCTCTCCGAGGCGCTGCGGTTGGAGTCGGCGCTGTTCATCGGCCTGTTCGGTACCGAGGACCGCCGCCAC
GGCATGGACTCGTTCATCGAGCGCGGCCCGGGCAAGGCCGACTTCGTCGGCCGCTAG

Upstream 100 bases:

>100_bases
GCTGCGGCCCGGCGGGGGAGTCTCCGGCGGGCGGGTGGCTCACGGATGCGCGGAATCGTGCTGAGGATTCATGGTTTCGC
GGCGATGCGGAGGTTTGGCG

Downstream 100 bases:

>100_bases
CCGTCGCAGCACCCGACATCGGCCCCGGCCCGGTCTGCGGCCCGGGGCCGGGTTGGTCAGCGTAGGGCCAGATCGGCGGT
CACCGGCTTGTGGTCGCTGT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MAVVRLEVSDGVGTIRLDRPPMNALNAALAAELRAAALEATARADVRAVVVYGGEKVFAAGADIKEMAGLDVAGITGWVR
DLAAAFDLVARIPKPVVAAVTGYALGGGLELALCADFRVFAENAKVGLPEITLGVIPGAGGTQRLPRLVGPARAKDLVFS
GRQVRAAEAEAIGLADKVVPADEVHAEALRMAGRFVTGPALALAAAKQAIDDGGDLALSEALRLESALFIGLFGTEDRRH
GMDSFIERGPGKADFVGR

Sequences:

>Translated_258_residues
MAVVRLEVSDGVGTIRLDRPPMNALNAALAAELRAAALEATARADVRAVVVYGGEKVFAAGADIKEMAGLDVAGITGWVR
DLAAAFDLVARIPKPVVAAVTGYALGGGLELALCADFRVFAENAKVGLPEITLGVIPGAGGTQRLPRLVGPARAKDLVFS
GRQVRAAEAEAIGLADKVVPADEVHAEALRMAGRFVTGPALALAAAKQAIDDGGDLALSEALRLESALFIGLFGTEDRRH
GMDSFIERGPGKADFVGR
>Mature_257_residues
AVVRLEVSDGVGTIRLDRPPMNALNAALAAELRAAALEATARADVRAVVVYGGEKVFAAGADIKEMAGLDVAGITGWVRD
LAAAFDLVARIPKPVVAAVTGYALGGGLELALCADFRVFAENAKVGLPEITLGVIPGAGGTQRLPRLVGPARAKDLVFSG
RQVRAAEAEAIGLADKVVPADEVHAEALRMAGRFVTGPALALAAAKQAIDDGGDLALSEALRLESALFIGLFGTEDRRHG
MDSFIERGPGKADFVGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=39.5161290322581, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI68989263, Length=217, Percent_Identity=41.0138248847926, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI4502327, Length=233, Percent_Identity=37.7682403433476, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI70995211, Length=237, Percent_Identity=31.2236286919831, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI20127408, Length=178, Percent_Identity=35.9550561797753, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI213417737, Length=233, Percent_Identity=27.8969957081545, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI157694516, Length=233, Percent_Identity=27.8969957081545, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI261878539, Length=121, Percent_Identity=47.9338842975207, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI150378541, Length=255, Percent_Identity=29.8039215686275, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI157694520, Length=210, Percent_Identity=27.6190476190476, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI62530384, Length=241, Percent_Identity=24.4813278008299, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31542718, Length=256, Percent_Identity=26.953125, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI45643119, Length=206, Percent_Identity=26.2135922330097, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI260275230, Length=206, Percent_Identity=26.2135922330097, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI260274832, Length=206, Percent_Identity=26.2135922330097, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI37594469, Length=188, Percent_Identity=28.1914893617021, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI37594471, Length=188, Percent_Identity=28.1914893617021, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787659, Length=249, Percent_Identity=43.7751004016064, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI221142681, Length=242, Percent_Identity=36.3636363636364, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788682, Length=191, Percent_Identity=37.696335078534, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790281, Length=181, Percent_Identity=34.2541436464088, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1788597, Length=266, Percent_Identity=29.6992481203008, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082183, Length=248, Percent_Identity=27.8225806451613, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787660, Length=270, Percent_Identity=32.962962962963, Blast_Score=87, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=249, Percent_Identity=40.5622489959839, Blast_Score=180, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI17554946, Length=241, Percent_Identity=41.9087136929461, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17540714, Length=222, Percent_Identity=35.5855855855856, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17558304, Length=181, Percent_Identity=37.5690607734807, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25144276, Length=181, Percent_Identity=37.5690607734807, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17508953, Length=181, Percent_Identity=37.5690607734807, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17508951, Length=181, Percent_Identity=37.5690607734807, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17560910, Length=207, Percent_Identity=29.4685990338164, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=244, Percent_Identity=27.4590163934426, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=233, Percent_Identity=23.175965665236, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=28.1853281853282, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17549921, Length=244, Percent_Identity=26.2295081967213, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=180, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=180, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=202, Percent_Identity=28.7128712871287, Blast_Score=82, Evalue=6e-17,
Organism=Drosophila melanogaster, GI20129971, Length=254, Percent_Identity=42.9133858267717, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24653477, Length=254, Percent_Identity=42.9133858267717, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24653139, Length=245, Percent_Identity=36.734693877551, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI21357171, Length=247, Percent_Identity=29.9595141700405, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19921000, Length=182, Percent_Identity=37.9120879120879, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24583077, Length=182, Percent_Identity=37.9120879120879, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24583079, Length=182, Percent_Identity=37.9120879120879, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19920382, Length=214, Percent_Identity=28.5046728971963, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19922422, Length=249, Percent_Identity=24.8995983935743, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19921018, Length=201, Percent_Identity=30.3482587064677, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24650670, Length=210, Percent_Identity=29.5238095238095, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24583165, Length=209, Percent_Identity=26.7942583732057, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571730, Length=181, Percent_Identity=25.9668508287293, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28571729, Length=181, Percent_Identity=25.9668508287293, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26617; Mature: 26486

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVVRLEVSDGVGTIRLDRPPMNALNAALAAELRAAALEATARADVRAVVVYGGEKVFAA
CEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEC
GADIKEMAGLDVAGITGWVRDLAAAFDLVARIPKPVVAAVTGYALGGGLELALCADFRVF
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCEEEEECCHHEE
AENAKVGLPEITLGVIPGAGGTQRLPRLVGPARAKDLVFSGRQVRAAEAEAIGLADKVVP
CCCCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHCCCEEEHHHHHHHCCHHHCCC
ADEVHAEALRMAGRFVTGPALALAAAKQAIDDGGDLALSEALRLESALFIGLFGTEDRRH
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEECCCHHHC
GMDSFIERGPGKADFVGR
CHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVVRLEVSDGVGTIRLDRPPMNALNAALAAELRAAALEATARADVRAVVVYGGEKVFAA
EEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEC
GADIKEMAGLDVAGITGWVRDLAAAFDLVARIPKPVVAAVTGYALGGGLELALCADFRVF
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCEEEEECCHHEE
AENAKVGLPEITLGVIPGAGGTQRLPRLVGPARAKDLVFSGRQVRAAEAEAIGLADKVVP
CCCCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHCCCEEEHHHHHHHCCHHHCCC
ADEVHAEALRMAGRFVTGPALALAAAKQAIDDGGDLALSEALRLESALFIGLFGTEDRRH
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEECCCHHHC
GMDSFIERGPGKADFVGR
CHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]