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The map label for this gene is wecA [H]

Identifier: 158312868

GI number: 158312868

Start: 1196645

End: 1197754

Strand: Direct

Name: wecA [H]

Synonym: Franean1_1014

Alternate gene names: 158312868

Gene position: 1196645-1197754 (Clockwise)

Preceding gene: 158312867

Following gene: 158312869

Centisome position: 13.32

GC content: 69.64

Gene sequence:

>1110_bases
ATGCGCGAGTATCTGCTCGTCTTCGCGGTGGCGGCGGCGGTCACCTTCCTCACGACGCCGATCGCCCGCTGGATCGCCTT
CCGTGTCGGGGCGGTCGCCCGGCCCCGGGCCCGGGACGTGCACGCGACGCCCACCCCGCGGCTCGGTGGCCTGGCGATGT
TGGCCGGGCTCTATGCGGGCCTCGAGGTGGCCGATCAACTGCCGTTCCTCTCCGTGGTCTCCCAGGACTGGTCGGAGACT
CGTGCCGTCCTGGTCGCCGGCACGCTGATCTGCCTGCTGGGGGCGGCCGACGACCGCTGGGAGCTGGACTCGCTGACCAA
GCTCGCCGGTCAGGTCGCGGCCGCCGGCGTCATGGTCCTGCTCGGCGTGCAGTGGTCCTTCGCGATCGACCGGAACAGCG
AGACCACACTCAGCTTCGGGCCGGAGACCGCCGTCCCGCTGTCCATCTTCGCCACGCTCATCCTGGTCAACGCGATGAAC
TTCATCGACGGCCTGGACGGGCTGGCCGCCGGGGTCGCCGCGATCGCGGCCGGTGCCACGTTCTATTTCGCCTACCAGAT
CGCGGTGATCAACGGCTTCTACCGGGCCTCACCGGCCGCGCTGCTCGCCGCGGTCACCGCCGGGGTGTGTGTCGGCTTCC
TTCCGCATAATTTCAACCCGGCCCGCCTGTTCATGGGGGATTCCGGCTCGATGCTCATCGGGCTGCTCTCGGCCGCCTCG
ATGATCTCGGTGACCGGTCAGGTCGCGTACGGGGGTTACGCTGGACCCTCCCAACAGCTTCCGTCGCTGATTCCGCTGGC
CATCCCGCTGGCGGTGCTGGCCGTCCCGGTGCTCGACTTCGGGCTCGCGGTCATCCGGCGGACGAAGGCGGGGCGCTCGC
CGTTCGCGGCAGACAAGATGCACCTGCATCATCGAATTCTTTCGATTGGCAACTCCCACGTCAGGGCGGTTCTGCTGATG
TACTTCTGGGCCGCGCTCGTCGGCTTCGGGGGAGTGGCGGCCTCCTTCTCCGACTCGCCGCTGCCGATCCTCGCCGCCAC
CGTCGGCGTGGGGCTGCTCGCGCTGCTCGCCCTTCTTCTGACGGGCCAGCGCGCGGCCCGGCGCGCATGA

Upstream 100 bases:

>100_bases
CGGCCTATCCGAGATAGCCGGGCGGCCGCGGGCGACCGCGCCGGCTGGCGCACGATGAGAGCCCGGGGCAGCGCAGGATG
AAACGGCGGAACAGGTAGGG

Downstream 100 bases:

>100_bases
TCGCCGCGGCTCGCCCGGCGCTGCGCGCCGGGTTGTGCACGATGGCGGTGCTGCTGGCTGTGGTCCTTGTACTGACCGGT
GCCATTCGGGGCGCGGCCGG

Product: glycosyl transferase family protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MREYLLVFAVAAAVTFLTTPIARWIAFRVGAVARPRARDVHATPTPRLGGLAMLAGLYAGLEVADQLPFLSVVSQDWSET
RAVLVAGTLICLLGAADDRWELDSLTKLAGQVAAAGVMVLLGVQWSFAIDRNSETTLSFGPETAVPLSIFATLILVNAMN
FIDGLDGLAAGVAAIAAGATFYFAYQIAVINGFYRASPAALLAAVTAGVCVGFLPHNFNPARLFMGDSGSMLIGLLSAAS
MISVTGQVAYGGYAGPSQQLPSLIPLAIPLAVLAVPVLDFGLAVIRRTKAGRSPFAADKMHLHHRILSIGNSHVRAVLLM
YFWAALVGFGGVAASFSDSPLPILAATVGVGLLALLALLLTGQRAARRA

Sequences:

>Translated_369_residues
MREYLLVFAVAAAVTFLTTPIARWIAFRVGAVARPRARDVHATPTPRLGGLAMLAGLYAGLEVADQLPFLSVVSQDWSET
RAVLVAGTLICLLGAADDRWELDSLTKLAGQVAAAGVMVLLGVQWSFAIDRNSETTLSFGPETAVPLSIFATLILVNAMN
FIDGLDGLAAGVAAIAAGATFYFAYQIAVINGFYRASPAALLAAVTAGVCVGFLPHNFNPARLFMGDSGSMLIGLLSAAS
MISVTGQVAYGGYAGPSQQLPSLIPLAIPLAVLAVPVLDFGLAVIRRTKAGRSPFAADKMHLHHRILSIGNSHVRAVLLM
YFWAALVGFGGVAASFSDSPLPILAATVGVGLLALLALLLTGQRAARRA
>Mature_369_residues
MREYLLVFAVAAAVTFLTTPIARWIAFRVGAVARPRARDVHATPTPRLGGLAMLAGLYAGLEVADQLPFLSVVSQDWSET
RAVLVAGTLICLLGAADDRWELDSLTKLAGQVAAAGVMVLLGVQWSFAIDRNSETTLSFGPETAVPLSIFATLILVNAMN
FIDGLDGLAAGVAAIAAGATFYFAYQIAVINGFYRASPAALLAAVTAGVCVGFLPHNFNPARLFMGDSGSMLIGLLSAAS
MISVTGQVAYGGYAGPSQQLPSLIPLAIPLAVLAVPVLDFGLAVIRRTKAGRSPFAADKMHLHHRILSIGNSHVRAVLLM
YFWAALVGFGGVAASFSDSPLPILAATVGVGLLALLALLLTGQRAARRA

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55), the lipid intermediate involved in the synthesis of various bacter

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=304, Percent_Identity=27.6315789473684, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 38441; Mature: 38441

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREYLLVFAVAAAVTFLTTPIARWIAFRVGAVARPRARDVHATPTPRLGGLAMLAGLYAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LEVADQLPFLSVVSQDWSETRAVLVAGTLICLLGAADDRWELDSLTKLAGQVAAAGVMVL
HHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGVQWSFAIDRNSETTLSFGPETAVPLSIFATLILVNAMNFIDGLDGLAAGVAAIAAGAT
HCCCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYFAYQIAVINGFYRASPAALLAAVTAGVCVGFLPHNFNPARLFMGDSGSMLIGLLSAAS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHH
MISVTGQVAYGGYAGPSQQLPSLIPLAIPLAVLAVPVLDFGLAVIRRTKAGRSPFAADKM
HHHHCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
HLHHRILSIGNSHVRAVLLMYFWAALVGFGGVAASFSDSPLPILAATVGVGLLALLALLL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGQRAARRA
CCCHHHCCC
>Mature Secondary Structure
MREYLLVFAVAAAVTFLTTPIARWIAFRVGAVARPRARDVHATPTPRLGGLAMLAGLYAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LEVADQLPFLSVVSQDWSETRAVLVAGTLICLLGAADDRWELDSLTKLAGQVAAAGVMVL
HHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGVQWSFAIDRNSETTLSFGPETAVPLSIFATLILVNAMNFIDGLDGLAAGVAAIAAGAT
HCCCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYFAYQIAVINGFYRASPAALLAAVTAGVCVGFLPHNFNPARLFMGDSGSMLIGLLSAAS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHH
MISVTGQVAYGGYAGPSQQLPSLIPLAIPLAVLAVPVLDFGLAVIRRTKAGRSPFAADKM
HHHHCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
HLHHRILSIGNSHVRAVLLMYFWAALVGFGGVAASFSDSPLPILAATVGVGLLALLALLL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TGQRAARRA
CCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]