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The map label for this gene is rho [H]

Identifier: 158312862

GI number: 158312862

Start: 1189908

End: 1191920

Strand: Direct

Name: rho [H]

Synonym: Franean1_1008

Alternate gene names: 158312862

Gene position: 1189908-1191920 (Clockwise)

Preceding gene: 158312861

Following gene: 158312863

Centisome position: 13.25

GC content: 74.07

Gene sequence:

>2013_bases
GTGCCGTCGGCCTCGTCGCCGACCTCCCAGCCCGCGTCCGCGCCGGCCTCCGTGGCCCCGGCCGCGCAGGGCGCTCCGCC
CGCGGCGGCTCCCGCCGCGGACGCGGTGAGCTCCGCGCCCCGGGCGGCGGCCGGCTCGGTCGCTCCCGTCCAGGAGACGA
GCGGTTCCAGCGGCGCCGAGGCGACCACGGGCGGCTCCGTTTCCGGCTCCGCGGCAGAGACGTCGTCGGCCCCGACCCGT
GTGCGCGGGCGGCGGGGCGCCTCTCGTGGCGTCACGAGCCCCGCGGGCGAGCAGCAGACACTGCCGACCGGTCCGGGGGG
TGCGGAGTCGTCCGACGACACCGCCCGCCCGCAGGCCGCCGCGGCTGCCGCGGACGGCCCGGCGGTGACCGCGCCCGCCG
CGGCGCCCGTCTCCGTCCGCGCCGGGACGAACGGCTCCGAGAGCCCCACGCGCGGTCGTGACGACCGCCGCGAGCGCTCC
GGTGACCGGGACCGCTCCGGCGGCGACCGGGACCGTTCGGGTGACCGTGACCGTTCCGGCGGCGACCGGGACCGTTCCGG
CGACCGCCAGGGCCGCTCACAGCCGGCCGGCGACCGCGACCGGAACGACCGTGCCGACCGCAGCGACCGTGCCGACCGTG
CCGACCGTGCCGACCGTGCCGACCGCAGCGATCGTGCCGACCGCAGCGACCGTGCCGGTTCAGACCGGTCCAGGACGGTC
GAGCGCACCCAGCCGGGCGACCGTGCACCCCAGGGCGGCGTCCAGGACGACGACGAGTTCGGCAGCCGGCGCCGCGGCCG
GTTCCGGGAGCGCGGCCGCAACCGCGGCCGCGGCGGGCAGGGCGGCACGACCGAGACCGAGCCGACGGTGCGCGAGGACG
ACGTCCTCGTCCCGGTGGCCGGCATCCTCGACGTGCTGGACAACTACGCCTTCGTCCGCACGAGCGGCTACCTGACCGGC
CCGACGGACGTGTACGTGAGCCTCGCCCAGGTCCGTCGCAACGGCCTGCGCCGCGGCGACGCGATCACCGGGGTGGTGCG
CGCGCCGCAGGAGGGCGAGCAGCGCCGCGACAAGTACAACGCGCTGGTCCGGCTGGACACGATCAACGGGATGGAGCCGG
AGGAGGCCCGCGGCCGGCCGGAGTTCCACAAGCTCACCCCGCTCTACCCGCAGGACCGCCTGCGGCTGGAGACCGAGCCG
CACATGATGACCACGCGGGTCATCGACCTGGTGATGCCGATCGGCAAGGGCCAGCGCGCGCTCATCGTGAGCCCGCCGAA
GGCCGGCAAGACGATGGTGCTCCAGTCGATCGCCAACGCGATCACCACGAACAACCCGGAATGCCACCTCATGGTCGTCC
TCGTCGACGAGCGGCCCGAGGAGGTCACCGACATGCAGCGGTCGGTGAAGGGCGAGGTCGTCGCCTCGACCTTCGACCGC
CCGCCGGCCGACCACACCAACGTCGCCGAGCTGTCCATCGAGCGGGCCAAGCGGCTCGTCGAGCTCGGCCACGACGTGGT
CGTGCTGCTCGACTCGATCACCCGGCTGGGTCGCGCCTACAACCTCGCGGCGCCGGCGTCGGGGCGCATCCTGTCCGGTG
GTGTCGACTCGACGGCGCTCTACCCGCCGAAGCGGTTCCTCGGCGCGGCGCGCAACATCGAGAACGGCGGCTCCCTGACG
ATCATCGCGACCGCGCTGGTCGAGACCGGTTCGACGATGGACACGGTGATCTTCGAGGAGTTCAAGGGCACCGGTAACGC
CGAGCTCAAGCTGGACCGGAAGATCGCCGACAAGCGGGTCTTCCCGGCGGTGGACGTCGACGCCTCCGGCACCCGCAAGG
AGGACATCCTGCTGGCCCCCGACGAGCTTGCGATCATGCACAAGCTCCGCCGGGTCCTGCACACCCGGGAGCCGCAGCAG
GCGCTCGACCTCCTGCTCGACCGGCTGAAGCAGACCAGGACGAACTACGAGTTCCTGATGCAGATCGCGAAGACGGCACC
GCCCCAGGACTGA

Upstream 100 bases:

>100_bases
GGCTTCCCAGATGGGCATCCCCGGGGTCGGCAGGCTCCGCAAGGGCCAGCTGATCGCGGCGATCCAGAACGTCCAGAACG
GTGAGGTGGCCTCCAGATCG

Downstream 100 bases:

>100_bases
CCGCCGCCCGGCGGCAGCCCCCGGCCGGGCCCGGGAACACCAGGGCCCGGCGGCGGCGTTGCCGTCGGCGGCTGGCTGGT
CCGGCCCGGGTCACCGGGTC

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MPSASSPTSQPASAPASVAPAAQGAPPAAAPAADAVSSAPRAAAGSVAPVQETSGSSGAEATTGGSVSGSAAETSSAPTR
VRGRRGASRGVTSPAGEQQTLPTGPGGAESSDDTARPQAAAAAADGPAVTAPAAAPVSVRAGTNGSESPTRGRDDRRERS
GDRDRSGGDRDRSGDRDRSGGDRDRSGDRQGRSQPAGDRDRNDRADRSDRADRADRADRADRSDRADRSDRAGSDRSRTV
ERTQPGDRAPQGGVQDDDEFGSRRRGRFRERGRNRGRGGQGGTTETEPTVREDDVLVPVAGILDVLDNYAFVRTSGYLTG
PTDVYVSLAQVRRNGLRRGDAITGVVRAPQEGEQRRDKYNALVRLDTINGMEPEEARGRPEFHKLTPLYPQDRLRLETEP
HMMTTRVIDLVMPIGKGQRALIVSPPKAGKTMVLQSIANAITTNNPECHLMVVLVDERPEEVTDMQRSVKGEVVASTFDR
PPADHTNVAELSIERAKRLVELGHDVVVLLDSITRLGRAYNLAAPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLT
IIATALVETGSTMDTVIFEEFKGTGNAELKLDRKIADKRVFPAVDVDASGTRKEDILLAPDELAIMHKLRRVLHTREPQQ
ALDLLLDRLKQTRTNYEFLMQIAKTAPPQD

Sequences:

>Translated_670_residues
MPSASSPTSQPASAPASVAPAAQGAPPAAAPAADAVSSAPRAAAGSVAPVQETSGSSGAEATTGGSVSGSAAETSSAPTR
VRGRRGASRGVTSPAGEQQTLPTGPGGAESSDDTARPQAAAAAADGPAVTAPAAAPVSVRAGTNGSESPTRGRDDRRERS
GDRDRSGGDRDRSGDRDRSGGDRDRSGDRQGRSQPAGDRDRNDRADRSDRADRADRADRADRSDRADRSDRAGSDRSRTV
ERTQPGDRAPQGGVQDDDEFGSRRRGRFRERGRNRGRGGQGGTTETEPTVREDDVLVPVAGILDVLDNYAFVRTSGYLTG
PTDVYVSLAQVRRNGLRRGDAITGVVRAPQEGEQRRDKYNALVRLDTINGMEPEEARGRPEFHKLTPLYPQDRLRLETEP
HMMTTRVIDLVMPIGKGQRALIVSPPKAGKTMVLQSIANAITTNNPECHLMVVLVDERPEEVTDMQRSVKGEVVASTFDR
PPADHTNVAELSIERAKRLVELGHDVVVLLDSITRLGRAYNLAAPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLT
IIATALVETGSTMDTVIFEEFKGTGNAELKLDRKIADKRVFPAVDVDASGTRKEDILLAPDELAIMHKLRRVLHTREPQQ
ALDLLLDRLKQTRTNYEFLMQIAKTAPPQD
>Mature_669_residues
PSASSPTSQPASAPASVAPAAQGAPPAAAPAADAVSSAPRAAAGSVAPVQETSGSSGAEATTGGSVSGSAAETSSAPTRV
RGRRGASRGVTSPAGEQQTLPTGPGGAESSDDTARPQAAAAAADGPAVTAPAAAPVSVRAGTNGSESPTRGRDDRRERSG
DRDRSGGDRDRSGDRDRSGGDRDRSGDRQGRSQPAGDRDRNDRADRSDRADRADRADRADRSDRADRSDRAGSDRSRTVE
RTQPGDRAPQGGVQDDDEFGSRRRGRFRERGRNRGRGGQGGTTETEPTVREDDVLVPVAGILDVLDNYAFVRTSGYLTGP
TDVYVSLAQVRRNGLRRGDAITGVVRAPQEGEQRRDKYNALVRLDTINGMEPEEARGRPEFHKLTPLYPQDRLRLETEPH
MMTTRVIDLVMPIGKGQRALIVSPPKAGKTMVLQSIANAITTNNPECHLMVVLVDERPEEVTDMQRSVKGEVVASTFDRP
PADHTNVAELSIERAKRLVELGHDVVVLLDSITRLGRAYNLAAPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLTI
IATALVETGSTMDTVIFEEFKGTGNAELKLDRKIADKRVFPAVDVDASGTRKEDILLAPDELAIMHKLRRVLHTREPQQA
LDLLLDRLKQTRTNYEFLMQIAKTAPPQD

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=367, Percent_Identity=57.7656675749319, Blast_Score=425, Evalue=1e-120,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 71486; Mature: 71355

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSASSPTSQPASAPASVAPAAQGAPPAAAPAADAVSSAPRAAAGSVAPVQETSGSSGAE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHCCCCCCCHHCCCCCCCC
ATTGGSVSGSAAETSSAPTRVRGRRGASRGVTSPAGEQQTLPTGPGGAESSDDTARPQAA
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
AAAADGPAVTAPAAAPVSVRAGTNGSESPTRGRDDRRERSGDRDRSGGDRDRSGDRDRSG
HHCCCCCCEECCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCC
GDRDRSGDRQGRSQPAGDRDRNDRADRSDRADRADRADRADRSDRADRSDRAGSDRSRTV
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCHHCCCCCHHHCH
ERTQPGDRAPQGGVQDDDEFGSRRRGRFRERGRNRGRGGQGGTTETEPTVREDDVLVPVA
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHH
GILDVLDNYAFVRTSGYLTGPTDVYVSLAQVRRNGLRRGDAITGVVRAPQEGEQRRDKYN
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHC
ALVRLDTINGMEPEEARGRPEFHKLTPLYPQDRLRLETEPHMMTTRVIDLVMPIGKGQRA
EEEEEECCCCCCCHHHCCCCCHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEE
LIVSPPKAGKTMVLQSIANAITTNNPECHLMVVLVDERPEEVTDMQRSVKGEVVASTFDR
EEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHHCCC
PPADHTNVAELSIERAKRLVELGHDVVVLLDSITRLGRAYNLAAPASGRILSGGVDSTAL
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCCCCC
YPPKRFLGAARNIENGGSLTIIATALVETGSTMDTVIFEEFKGTGNAELKLDRKIADKRV
CCCHHHHHHHHCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHCCCC
FPAVDVDASGTRKEDILLAPDELAIMHKLRRVLHTREPQQALDLLLDRLKQTRTNYEFLM
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHH
QIAKTAPPQD
HHHHHCCCCC
>Mature Secondary Structure 
PSASSPTSQPASAPASVAPAAQGAPPAAAPAADAVSSAPRAAAGSVAPVQETSGSSGAE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHCCCCCCCHHCCCCCCCC
ATTGGSVSGSAAETSSAPTRVRGRRGASRGVTSPAGEQQTLPTGPGGAESSDDTARPQAA
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
AAAADGPAVTAPAAAPVSVRAGTNGSESPTRGRDDRRERSGDRDRSGGDRDRSGDRDRSG
HHCCCCCCEECCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCC
GDRDRSGDRQGRSQPAGDRDRNDRADRSDRADRADRADRADRSDRADRSDRAGSDRSRTV
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCHHCCCCCHHHCH
ERTQPGDRAPQGGVQDDDEFGSRRRGRFRERGRNRGRGGQGGTTETEPTVREDDVLVPVA
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHH
GILDVLDNYAFVRTSGYLTGPTDVYVSLAQVRRNGLRRGDAITGVVRAPQEGEQRRDKYN
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHC
ALVRLDTINGMEPEEARGRPEFHKLTPLYPQDRLRLETEPHMMTTRVIDLVMPIGKGQRA
EEEEEECCCCCCCHHHCCCCCHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEE
LIVSPPKAGKTMVLQSIANAITTNNPECHLMVVLVDERPEEVTDMQRSVKGEVVASTFDR
EEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHHCCC
PPADHTNVAELSIERAKRLVELGHDVVVLLDSITRLGRAYNLAAPASGRILSGGVDSTAL
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECCCCCCCCEEECCCCCCCC
YPPKRFLGAARNIENGGSLTIIATALVETGSTMDTVIFEEFKGTGNAELKLDRKIADKRV
CCCHHHHHHHHCCCCCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHCCCC
FPAVDVDASGTRKEDILLAPDELAIMHKLRRVLHTREPQQALDLLLDRLKQTRTNYEFLM
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHH
QIAKTAPPQD
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8702978 [H]