Click here to switch to the map view.

The map label for this gene is moaE1 [H]

Identifier: 158312795

GI number: 158312795

Start: 1102134

End: 1102580

Strand: Direct

Name: moaE1 [H]

Synonym: Franean1_0941

Alternate gene names: 158312795

Gene position: 1102134-1102580 (Clockwise)

Preceding gene: 158312791

Following gene: 158312796

Centisome position: 12.27

GC content: 68.01

Gene sequence:

>447_bases
GTGCCCGTTGTCGACGGTGTGGCCCGAGGTGTCGTCGTTCTTGCGGAGATGCGTGAATTGCCGCTCTCTGTCGACGAATG
CCTGGCCGCCGTGCGGTTGCCGGAGGTCGGTGGAATCGGTCTCTTCATCGGCACCGTCCGCGATCATGATCATGACAGGT
CGGTGGTGGACCTCGAGTACAGCGCGCATCCCCGGGCCGCTGACGAGCTGGCCCGGGTGGCCGGCGATGTGGCCGCTGAG
CTGGGCGTTCACGCCATAGCGGTGCTGCACCGGACGGGTCGGCTGGCGATCGGGGACATCGCGGTCGTCGTGGCCGCCGG
TGCCGTGCACCGCGCGGAGGCACTGGAGGCCTGTCGGCGCCTCATCGACGACGTGAAGGAACAGGTGCCCATCTGGAAGC
GCCAGGCATTCGCCGATGGCGCGACAGAATGGGTAGGCGCCTGCTGA

Upstream 100 bases:

>100_bases
TAGGGACATGAACCCACGGTAGTGCGTTTTCCGGCCGACCGGTGAAACGGAGTCGGCCGGGCGTTACCGTCAGGGGGTGG
ATGTGACCTGCTCGGATCCG

Downstream 100 bases:

>100_bases
GCGGGGCACCTAGGATAGATATTGGTCATCTTCCTTCCCCCGTCTCGACGTCGAGGCCGCCATGTGGTTCCTGCTGATCC
CACCTGTCGCGGTGCTCCTG

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E 1; Molybdopterin-converting factor large subunit 1; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MPVVDGVARGVVVLAEMRELPLSVDECLAAVRLPEVGGIGLFIGTVRDHDHDRSVVDLEYSAHPRAADELARVAGDVAAE
LGVHAIAVLHRTGRLAIGDIAVVVAAGAVHRAEALEACRRLIDDVKEQVPIWKRQAFADGATEWVGAC

Sequences:

>Translated_148_residues
MPVVDGVARGVVVLAEMRELPLSVDECLAAVRLPEVGGIGLFIGTVRDHDHDRSVVDLEYSAHPRAADELARVAGDVAAE
LGVHAIAVLHRTGRLAIGDIAVVVAAGAVHRAEALEACRRLIDDVKEQVPIWKRQAFADGATEWVGAC
>Mature_147_residues
PVVDGVARGVVVLAEMRELPLSVDECLAAVRLPEVGGIGLFIGTVRDHDHDRSVVDLEYSAHPRAADELARVAGDVAAEL
GVHAIAVLHRTGRLAIGDIAVVVAAGAVHRAEALEACRRLIDDVKEQVPIWKRQAFADGATEWVGAC

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=126, Percent_Identity=38.0952380952381, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787003, Length=129, Percent_Identity=32.5581395348837, Blast_Score=62, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509279, Length=114, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356259, Length=111, Percent_Identity=35.1351351351351, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 15699; Mature: 15568

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVVDGVARGVVVLAEMRELPLSVDECLAAVRLPEVGGIGLFIGTVRDHDHDRSVVDLEY
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEC
SAHPRAADELARVAGDVAAELGVHAIAVLHRTGRLAIGDIAVVVAAGAVHRAEALEACRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
LIDDVKEQVPIWKRQAFADGATEWVGAC
HHHHHHHHCCHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure 
PVVDGVARGVVVLAEMRELPLSVDECLAAVRLPEVGGIGLFIGTVRDHDHDRSVVDLEY
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEEC
SAHPRAADELARVAGDVAAELGVHAIAVLHRTGRLAIGDIAVVVAAGAVHRAEALEACRR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
LIDDVKEQVPIWKRQAFADGATEWVGAC
HHHHHHHHCCHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]