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The map label for this gene is galE [H]

Identifier: 158312644

GI number: 158312644

Start: 915311

End: 916339

Strand: Direct

Name: galE [H]

Synonym: Franean1_0788

Alternate gene names: 158312644

Gene position: 915311-916339 (Clockwise)

Preceding gene: 158312642

Following gene: 158312645

Centisome position: 10.19

GC content: 68.22

Gene sequence:

>1029_bases
ATGAAGGTGCTCGTCACCGGTACGGAGGGCTACCTGGGCTGCCTGCTTGCCCCGGAGCTGCTGCGCGACGGCCACGACGT
GGTCGGGGTGGACACCGGTTACTACAAGTACGGCTGGCTCTACCGCGGCACGGACCGTGTCCCGCACACGATCGACAAGG
ACCTGCGCGACCTCACCGTCGAGGATTTCGAGGGCGTCGACGCGGTCGTGCACATGGCGGAGCTGTCGAACGACCCGCTG
GGCGCGCTGGCACCCGACGTGACCTACAAGGTGAACCACCAGGGGTCCGTGCGGCTCGCGAAGCTGGCGAAGCAGGCCGG
CGTCCAGCGGTTCGTCTACATGTCGTCGTGCAGCGTCTACGGCGTCGCGACCGGGTCGGACGTCACGGAGACCTCGCCGG
TCAACCCGCAGACGCCGTACGCCGAGTGCAAGGTCTACGTCGAGCGGGACGTCGCGCCGCTGGCGGACGACACCTTCTCA
CCGACGTTCCTGCGCAACGCCACCGCGTACGGCGCCTCGCCGCGGATGCGGTTCGACATCGTGCTGAACAACCTGGCCGG
GGTCGCCTGGACCACGAACGAGATCGCGATGACCTCGGACGGCACCCCGTGGCGCCCGCTGGTGCACGGCCTGGACATCG
CCAAGGCGATCCGGTGCGTGCTCACCGCGCCGCGCGACGCCGTCCACAACGAGATCTTCAACGTGGGTGACAGCGCGCAG
AACTACCAGGTGAAGGAGATCGCGGACGCGGTCGCCACCGTCTTCACCGGCTGCAAGCTGAGCTTCGGCGACAACGGCGG
GGACAACCGCAGCTACCGGGTGTCGTTCGACAAGATCGCCTCCCAGCTCCCGGGCTTCTCCTGCGACTGGGACGCGCACA
AGGGAGCCGAGCAGCTCCACGAGGTGTTCAGCCGCATCCAGCTCGACACCGAGACGTTCACCGGCCGCGGGCACACCCGG
CTCAAGCAGCTGCAGTACCTGATCGGCACCGGCCAGGTCGACGCCGAGCTGTTCTGGACCGCCCGGTGA

Upstream 100 bases:

>100_bases
ACTGGCGGGCACCTCCGGCCCTCTCGGTACCTTCTGTGGTCGGAGCGCAGGGCCGTCGTCGAACCCCGCGTGCCCTCGTC
GAGATCGGGAGGACTCTCGG

Downstream 100 bases:

>100_bases
AGCTCACGCCCACCGCCATCGACGGCGTGACGATCGTCGACGTCGAGGCGTTCTCGGACGACCGCGGCCTGTTCGCGCGC
ACCTTCTGCCAGGAGGAGTT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKVLVTGTEGYLGCLLAPELLRDGHDVVGVDTGYYKYGWLYRGTDRVPHTIDKDLRDLTVEDFEGVDAVVHMAELSNDPL
GALAPDVTYKVNHQGSVRLAKLAKQAGVQRFVYMSSCSVYGVATGSDVTETSPVNPQTPYAECKVYVERDVAPLADDTFS
PTFLRNATAYGASPRMRFDIVLNNLAGVAWTTNEIAMTSDGTPWRPLVHGLDIAKAIRCVLTAPRDAVHNEIFNVGDSAQ
NYQVKEIADAVATVFTGCKLSFGDNGGDNRSYRVSFDKIASQLPGFSCDWDAHKGAEQLHEVFSRIQLDTETFTGRGHTR
LKQLQYLIGTGQVDAELFWTAR

Sequences:

>Translated_342_residues
MKVLVTGTEGYLGCLLAPELLRDGHDVVGVDTGYYKYGWLYRGTDRVPHTIDKDLRDLTVEDFEGVDAVVHMAELSNDPL
GALAPDVTYKVNHQGSVRLAKLAKQAGVQRFVYMSSCSVYGVATGSDVTETSPVNPQTPYAECKVYVERDVAPLADDTFS
PTFLRNATAYGASPRMRFDIVLNNLAGVAWTTNEIAMTSDGTPWRPLVHGLDIAKAIRCVLTAPRDAVHNEIFNVGDSAQ
NYQVKEIADAVATVFTGCKLSFGDNGGDNRSYRVSFDKIASQLPGFSCDWDAHKGAEQLHEVFSRIQLDTETFTGRGHTR
LKQLQYLIGTGQVDAELFWTAR
>Mature_342_residues
MKVLVTGTEGYLGCLLAPELLRDGHDVVGVDTGYYKYGWLYRGTDRVPHTIDKDLRDLTVEDFEGVDAVVHMAELSNDPL
GALAPDVTYKVNHQGSVRLAKLAKQAGVQRFVYMSSCSVYGVATGSDVTETSPVNPQTPYAECKVYVERDVAPLADDTFS
PTFLRNATAYGASPRMRFDIVLNNLAGVAWTTNEIAMTSDGTPWRPLVHGLDIAKAIRCVLTAPRDAVHNEIFNVGDSAQ
NYQVKEIADAVATVFTGCKLSFGDNGGDNRSYRVSFDKIASQLPGFSCDWDAHKGAEQLHEVFSRIQLDTETFTGRGHTR
LKQLQYLIGTGQVDAELFWTAR

Specific function: Can have functions other than metabolism of galactose. It also could be involved in preparation of carbohydrate residues for incorporation into complex polymers, such as exopolysaccharides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=287, Percent_Identity=27.5261324041812, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI56118217, Length=287, Percent_Identity=27.5261324041812, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI189083684, Length=287, Percent_Identity=27.5261324041812, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786974, Length=286, Percent_Identity=29.7202797202797, Blast_Score=78, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=245, Percent_Identity=27.7551020408163, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37568; Mature: 37568

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGTEGYLGCLLAPELLRDGHDVVGVDTGYYKYGWLYRGTDRVPHTIDKDLRDLTV
CEEEEECCCCHHHHHCCHHHHHCCCCEEEECCCCEEEEEEEECCCCCCCHHHHHHHHCCH
EDFEGVDAVVHMAELSNDPLGALAPDVTYKVNHQGSVRLAKLAKQAGVQRFVYMSSCSVY
HHCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCHHEEEEEECCCEE
GVATGSDVTETSPVNPQTPYAECKVYVERDVAPLADDTFSPTFLRNATAYGASPRMRFDI
EEECCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEE
VLNNLAGVAWTTNEIAMTSDGTPWRPLVHGLDIAKAIRCVLTAPRDAVHNEIFNVGDSAQ
EECCCCCCEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
NYQVKEIADAVATVFTGCKLSFGDNGGDNRSYRVSFDKIASQLPGFSCDWDAHKGAEQLH
CCHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCCCHHHHH
EVFSRIQLDTETFTGRGHTRLKQLQYLIGTGQVDAELFWTAR
HHHHHHCCCCHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure
MKVLVTGTEGYLGCLLAPELLRDGHDVVGVDTGYYKYGWLYRGTDRVPHTIDKDLRDLTV
CEEEEECCCCHHHHHCCHHHHHCCCCEEEECCCCEEEEEEEECCCCCCCHHHHHHHHCCH
EDFEGVDAVVHMAELSNDPLGALAPDVTYKVNHQGSVRLAKLAKQAGVQRFVYMSSCSVY
HHCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCHHEEEEEECCCEE
GVATGSDVTETSPVNPQTPYAECKVYVERDVAPLADDTFSPTFLRNATAYGASPRMRFDI
EEECCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEE
VLNNLAGVAWTTNEIAMTSDGTPWRPLVHGLDIAKAIRCVLTAPRDAVHNEIFNVGDSAQ
EECCCCCCEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
NYQVKEIADAVATVFTGCKLSFGDNGGDNRSYRVSFDKIASQLPGFSCDWDAHKGAEQLH
CCHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCCCHHHHH
EVFSRIQLDTETFTGRGHTRLKQLQYLIGTGQVDAELFWTAR
HHHHHHCCCCHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788721 [H]