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The map label for this gene is hbpA [H]

Identifier: 158312311

GI number: 158312311

Start: 529072

End: 530640

Strand: Direct

Name: hbpA [H]

Synonym: Franean1_0449

Alternate gene names: 158312311

Gene position: 529072-530640 (Clockwise)

Preceding gene: 158312309

Following gene: 158312312

Centisome position: 5.89

GC content: 63.61

Gene sequence:

>1569_bases
ATGATAGACGGCGCATTATCCCGCAGGCAGGTACTCGGCGCCGCACTCGCTACGGTGGCACTCGCCGGCGCGAGTTCGTG
CGCCGGCGAGGAACAATCGTCCGGCGACGGTGGCAGCGGACGGCCGTCCGCGTCGCGCGAACAGACATTGTCCCTTGCCA
TCCAGGCCACTCCGAATTCCTTCGATCCCGCTGAACTGACAAGCGGCCAGTCCTCGTTCGTGTGGAGCGCCCTCTACGAC
ACCCTGATATGGAAGGACAATAAGGGCAAGTTACAGCCCAACGCGGCAGAGAGCTGGAACTACTCCGACGGCGGGCGCAC
ACTGACATTGAAGCTGCGCAAGGGAATGTCCTTCAGCTCGGGTGCCCCGGTGAACGCGGTCGCGGTGAAGACCACCCTCG
AGCGGAGCAAGAACACGCCAGGATTCACCGACCAAGTCCTCGGCGCGCTCGAATCGGTCGACGCGCCCGACGACCGCACC
GTCGTCCTCCGACTCTCCCATCCGGACGGCGCACTGCTGGACTCGCTGGCAGTGAGCGGCGCGGGCGTGATCGGCGATCC
AGCGACGCTGAACGACAAACGTACCGCGCTGAACCCGGTCGGTTCGGGCCCATACGTCCTGAACACCGGACAGACGGTGA
ACGGATCGACCTACGTGCTCGATCGCCGCGAGGACTACTGGAACGTTCAGGCGTACCCGTTCAAGACCGTCAAAATCTCG
GTCATCCGGGACCGAACCGCTGCCCTCAACGCCCTGCAGGCGGGTGAGGTCAACGCCGGTACCGTCGAGGTGACAAACGT
GGACCGGCTGCGGGCGGCCGGCTTTGACGCCGCCGTCGTCGAGGCCCACTCGCTGGCCTCGCTGGTTCTCGCCGACCGTA
CAGGGGAGTCGCTCAAACCGCTGGGCGATCCACGGGTCCGGCAAGCCATCAACATGGCGTTCGACCGCGAGAAGATCGTC
GAACAGCTGCTCAGGGGCTCGGGTAAGCCGACCGAGCAGGTGTTCAACCCCAAGGACCCGGCGTATGACCCGGCACTGAA
CACGACGTACGCCTACGATCCACAGCGCGCGAAGAGACTGCTGGCCGAGGCCGGATATCCCAACGGATTCTCGGTAACGA
TGCCGGAATTTTTCTTAGCCAAGTCGTTCGCACCGACAATCACCCAGTCCCTGGCCGCTATCGGAATCACGACGACGTGG
GAACCGGTTCCCCCACAGCAGACCGACGCGGCGATCAGCTCGAAGAAATATCCGGCGTTCTTCCTAATTGCCGGGCTGGA
GACGACTGCGGGTGACGCGTCCAGATATTTCTCCAAGGACGGAGCGTTCAACCCCTTCCACGCGGAGGATCCGGACCTCA
CGCCACAGGTGGAGCAGGCGACTCAGACAATTGATCCGCGGCAGGCAGCCGATGCCTACAGGCATGTCAACGCCACCGCG
GTCCGGGATGCGTGGAACGCCCCCCTCTTCTACGTCGCGGTCCACTGGGTAACCAAAAAAGGCATCACCTATCTCGGTGA
CGGCTCGCTGACGTTCAACACCGTTCGCGCCTTCGGCCTGTCCGGATAA

Upstream 100 bases:

>100_bases
GTCGCGGGTCTGAGTTCCACCGGCTCCGACGTGGACCTGTGAACAACAGTCCATGTCTCTGGTCGCTACCCAAGTCACTT
CTTGCAGAGAAGAGGATCTT

Downstream 100 bases:

>100_bases
CGGAGAACACCTTGCTAGCCTATGTACTCCGGCGGCTCGGCGCAGGTGTGGTGCTCGCTCTCCTCGTCACATTGATCACG
TTCTTCCTGCTGAGCCTTTC

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MIDGALSRRQVLGAALATVALAGASSCAGEEQSSGDGGSGRPSASREQTLSLAIQATPNSFDPAELTSGQSSFVWSALYD
TLIWKDNKGKLQPNAAESWNYSDGGRTLTLKLRKGMSFSSGAPVNAVAVKTTLERSKNTPGFTDQVLGALESVDAPDDRT
VVLRLSHPDGALLDSLAVSGAGVIGDPATLNDKRTALNPVGSGPYVLNTGQTVNGSTYVLDRREDYWNVQAYPFKTVKIS
VIRDRTAALNALQAGEVNAGTVEVTNVDRLRAAGFDAAVVEAHSLASLVLADRTGESLKPLGDPRVRQAINMAFDREKIV
EQLLRGSGKPTEQVFNPKDPAYDPALNTTYAYDPQRAKRLLAEAGYPNGFSVTMPEFFLAKSFAPTITQSLAAIGITTTW
EPVPPQQTDAAISSKKYPAFFLIAGLETTAGDASRYFSKDGAFNPFHAEDPDLTPQVEQATQTIDPRQAADAYRHVNATA
VRDAWNAPLFYVAVHWVTKKGITYLGDGSLTFNTVRAFGLSG

Sequences:

>Translated_522_residues
MIDGALSRRQVLGAALATVALAGASSCAGEEQSSGDGGSGRPSASREQTLSLAIQATPNSFDPAELTSGQSSFVWSALYD
TLIWKDNKGKLQPNAAESWNYSDGGRTLTLKLRKGMSFSSGAPVNAVAVKTTLERSKNTPGFTDQVLGALESVDAPDDRT
VVLRLSHPDGALLDSLAVSGAGVIGDPATLNDKRTALNPVGSGPYVLNTGQTVNGSTYVLDRREDYWNVQAYPFKTVKIS
VIRDRTAALNALQAGEVNAGTVEVTNVDRLRAAGFDAAVVEAHSLASLVLADRTGESLKPLGDPRVRQAINMAFDREKIV
EQLLRGSGKPTEQVFNPKDPAYDPALNTTYAYDPQRAKRLLAEAGYPNGFSVTMPEFFLAKSFAPTITQSLAAIGITTTW
EPVPPQQTDAAISSKKYPAFFLIAGLETTAGDASRYFSKDGAFNPFHAEDPDLTPQVEQATQTIDPRQAADAYRHVNATA
VRDAWNAPLFYVAVHWVTKKGITYLGDGSLTFNTVRAFGLSG
>Mature_522_residues
MIDGALSRRQVLGAALATVALAGASSCAGEEQSSGDGGSGRPSASREQTLSLAIQATPNSFDPAELTSGQSSFVWSALYD
TLIWKDNKGKLQPNAAESWNYSDGGRTLTLKLRKGMSFSSGAPVNAVAVKTTLERSKNTPGFTDQVLGALESVDAPDDRT
VVLRLSHPDGALLDSLAVSGAGVIGDPATLNDKRTALNPVGSGPYVLNTGQTVNGSTYVLDRREDYWNVQAYPFKTVKIS
VIRDRTAALNALQAGEVNAGTVEVTNVDRLRAAGFDAAVVEAHSLASLVLADRTGESLKPLGDPRVRQAINMAFDREKIV
EQLLRGSGKPTEQVFNPKDPAYDPALNTTYAYDPQRAKRLLAEAGYPNGFSVTMPEFFLAKSFAPTITQSLAAIGITTTW
EPVPPQQTDAAISSKKYPAFFLIAGLETTAGDASRYFSKDGAFNPFHAEDPDLTPQVEQATQTIDPRQAADAYRHVNATA
VRDAWNAPLFYVAVHWVTKKGITYLGDGSLTFNTVRAFGLSG

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787052, Length=356, Percent_Identity=28.6516853932584, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1789966, Length=372, Percent_Identity=26.3440860215054, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789887, Length=316, Percent_Identity=24.3670886075949, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787762, Length=295, Percent_Identity=28.4745762711864, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787551, Length=434, Percent_Identity=25.5760368663594, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 55670; Mature: 55670

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDGALSRRQVLGAALATVALAGASSCAGEEQSSGDGGSGRPSASREQTLSLAIQATPNS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCC
FDPAELTSGQSSFVWSALYDTLIWKDNKGKLQPNAAESWNYSDGGRTLTLKLRKGMSFSS
CCCHHHCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCC
GAPVNAVAVKTTLERSKNTPGFTDQVLGALESVDAPDDRTVVLRLSHPDGALLDSLAVSG
CCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCC
AGVIGDPATLNDKRTALNPVGSGPYVLNTGQTVNGSTYVLDRREDYWNVQAYPFKTVKIS
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEECCCEEEEECCCCCCCEEEEEEEEEEEE
VIRDRTAALNALQAGEVNAGTVEVTNVDRLRAAGFDAAVVEAHSLASLVLADRTGESLKP
EEECCHHHHHHHHCCCCCCCEEEEECCHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCCC
LGDPRVRQAINMAFDREKIVEQLLRGSGKPTEQVFNPKDPAYDPALNTTYAYDPQRAKRL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCEEECHHHHHHH
LAEAGYPNGFSVTMPEFFLAKSFAPTITQSLAAIGITTTWEPVPPQQTDAAISSKKYPAF
HHHCCCCCCCEEECHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCEE
FLIAGLETTAGDASRYFSKDGAFNPFHAEDPDLTPQVEQATQTIDPRQAADAYRHVNATA
EEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHH
VRDAWNAPLFYVAVHWVTKKGITYLGDGSLTFNTVRAFGLSG
HHHCCCCCEEEEEEEEHHHCCCEEEECCCEEEEEHEECCCCC
>Mature Secondary Structure
MIDGALSRRQVLGAALATVALAGASSCAGEEQSSGDGGSGRPSASREQTLSLAIQATPNS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCC
FDPAELTSGQSSFVWSALYDTLIWKDNKGKLQPNAAESWNYSDGGRTLTLKLRKGMSFSS
CCCHHHCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCC
GAPVNAVAVKTTLERSKNTPGFTDQVLGALESVDAPDDRTVVLRLSHPDGALLDSLAVSG
CCCCEEEEEEEHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCC
AGVIGDPATLNDKRTALNPVGSGPYVLNTGQTVNGSTYVLDRREDYWNVQAYPFKTVKIS
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEECCCEEEEECCCCCCCEEEEEEEEEEEE
VIRDRTAALNALQAGEVNAGTVEVTNVDRLRAAGFDAAVVEAHSLASLVLADRTGESLKP
EEECCHHHHHHHHCCCCCCCEEEEECCHHHHHCCCCHHHHHHHHHHHHHEECCCCCCCCC
LGDPRVRQAINMAFDREKIVEQLLRGSGKPTEQVFNPKDPAYDPALNTTYAYDPQRAKRL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCEEECHHHHHHH
LAEAGYPNGFSVTMPEFFLAKSFAPTITQSLAAIGITTTWEPVPPQQTDAAISSKKYPAF
HHHCCCCCCCEEECHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCEE
FLIAGLETTAGDASRYFSKDGAFNPFHAEDPDLTPQVEQATQTIDPRQAADAYRHVNATA
EEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHH
VRDAWNAPLFYVAVHWVTKKGITYLGDGSLTFNTVRAFGLSG
HHHCCCCCEEEEEEEEHHHCCCEEEECCCEEEEEHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]