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The map label for this gene is aprE [H]

Identifier: 157964017

GI number: 157964017

Start: 5102597

End: 5103910

Strand: Reverse

Name: aprE [H]

Synonym: Spea_4206

Alternate gene names: 157964017

Gene position: 5103910-5102597 (Counterclockwise)

Preceding gene: 157964018

Following gene: 157964016

Centisome position: 98.63

GC content: 50.3

Gene sequence:

>1314_bases
ATGAGCGGCCGTCTCCATATAAAGCACCTTGAGGGTGCTAAGCGCGCTAACCAACTGATTTTTCTGGTGGCGGCCTTGAT
TGTCGTGACCCTAGTCTGGGCCTCATTTGCCAAGCTCGAAGAGGTAGTGGTGGGTGAAGGCATGGTAGTGCCGACATTAG
CCGTGCAGCAGATTGAGAGTCTAGATGGCGGGATCTTAAAACAGGTATTAGTTAGGGAGGGACAGTCAGTCTCGGCGGGA
GAGCCGCTATTACTGCTCGATGAACTTCGTTTTGCATCGGCCTACGATGAGGCCAATATTCAAGCCGCTGCGCTTAAACG
GCAAAAGGCACGCTTAGATGCAGAGATTAGCAGCGTGGTTATTGATGATGCAGCGAGCTACTGGCGCGATAAAGTGCTAA
TCAAGCCGAAGGCAATCAGTGCACTCGATGTGTCGGTCAGTACCCGCTCGAAAGCGATTTATCGTTCGCGATTATCTCAG
TTGTCATCACAGTTAGAGCAATCGGCGCAGGTGATAGAGCAAAAAGTACAAGCGATAGAAGAGGGGCTGATCACCACTCA
GGCACAGCTCAGTGGTTTGCAGTTAGTAAAGCAGGAAATCGTGATGACCCGCGCGGCGGTGCGAGAGGGCGCGGTTGCGG
AGCTAGAGCTATTAAAGCTTGAGCGTGATGAGATCCGCTTGAAAGGCGAGTTATCGGCATCGAAGGCTAACGGTCGTCAA
CTACGTGCGGCGCAGAATCAAGCCGAAGCTGAGTATCTCACCGTGGCTTTAGACTTCTTAAGCCGTGCGGAAGCCGAGCG
TAATGAAGTGATTAATGAACTCAATGCCCTCACCGAGAGCATCAAAACCCTTGCCGATCGCTTGGCTAGAACTCAAATTG
TTTCACCTATCAATGGCAATGTGACCAATATCTTAGTGCGTTCCATTGGTGCGGTGGTTGAGCCAGGCGAATCAATCATG
GGCATAGTGCCTCAGGACGGCGCTTTGATCATTGAAACTCGAATCGCCCCCAAAGACATCGCCTTTGTGCACACTGGGCT
GCAGGCAACCGTTAAATTTACCGCCTATGACTTCGTGATATATGGCGGCCTCAAAGGTGAGGTGATCTATGTGAGCCCGG
ATGCTCAACAGCTAGATGACGGCACCACCTATTTCGAAGCCCATATAAAAACAGAAGAAAACGTACTCAATGGCTGGCCG
ATTATTTCAGGAATGCAAGCCAGTACCGACATATTAACCGGTGAGAAAACCGTTTTAAATTATTGGCTAAAGCCTCTATT
ACGCGCTAAAGCAAATGCACTTCGCGAACCATAA

Upstream 100 bases:

>100_bases
ATAAGGGACGCATCATTCAAGAGCAAACCCCTGATGAGATGCGTCAACGTGGCAAGAGTCGTATCAAAGCGGTGAATGTG
CGTCAGAAAGGAGAGCTGAA

Downstream 100 bases:

>100_bases
GGTAAGGACACGATGCGACGACTGATACTTATACCAATACTGGCATTATCGGCTCAGGCGCAGGCTCTCACACTTGAAGA
GTCTGTGGCGGAAGCGATTA

Product: HlyD family type I secretion membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSGRLHIKHLEGAKRANQLIFLVAALIVVTLVWASFAKLEEVVVGEGMVVPTLAVQQIESLDGGILKQVLVREGQSVSAG
EPLLLLDELRFASAYDEANIQAAALKRQKARLDAEISSVVIDDAASYWRDKVLIKPKAISALDVSVSTRSKAIYRSRLSQ
LSSQLEQSAQVIEQKVQAIEEGLITTQAQLSGLQLVKQEIVMTRAAVREGAVAELELLKLERDEIRLKGELSASKANGRQ
LRAAQNQAEAEYLTVALDFLSRAEAERNEVINELNALTESIKTLADRLARTQIVSPINGNVTNILVRSIGAVVEPGESIM
GIVPQDGALIIETRIAPKDIAFVHTGLQATVKFTAYDFVIYGGLKGEVIYVSPDAQQLDDGTTYFEAHIKTEENVLNGWP
IISGMQASTDILTGEKTVLNYWLKPLLRAKANALREP

Sequences:

>Translated_437_residues
MSGRLHIKHLEGAKRANQLIFLVAALIVVTLVWASFAKLEEVVVGEGMVVPTLAVQQIESLDGGILKQVLVREGQSVSAG
EPLLLLDELRFASAYDEANIQAAALKRQKARLDAEISSVVIDDAASYWRDKVLIKPKAISALDVSVSTRSKAIYRSRLSQ
LSSQLEQSAQVIEQKVQAIEEGLITTQAQLSGLQLVKQEIVMTRAAVREGAVAELELLKLERDEIRLKGELSASKANGRQ
LRAAQNQAEAEYLTVALDFLSRAEAERNEVINELNALTESIKTLADRLARTQIVSPINGNVTNILVRSIGAVVEPGESIM
GIVPQDGALIIETRIAPKDIAFVHTGLQATVKFTAYDFVIYGGLKGEVIYVSPDAQQLDDGTTYFEAHIKTEENVLNGWP
IISGMQASTDILTGEKTVLNYWLKPLLRAKANALREP
>Mature_436_residues
SGRLHIKHLEGAKRANQLIFLVAALIVVTLVWASFAKLEEVVVGEGMVVPTLAVQQIESLDGGILKQVLVREGQSVSAGE
PLLLLDELRFASAYDEANIQAAALKRQKARLDAEISSVVIDDAASYWRDKVLIKPKAISALDVSVSTRSKAIYRSRLSQL
SSQLEQSAQVIEQKVQAIEEGLITTQAQLSGLQLVKQEIVMTRAAVREGAVAELELLKLERDEIRLKGELSASKANGRQL
RAAQNQAEAEYLTVALDFLSRAEAERNEVINELNALTESIKTLADRLARTQIVSPINGNVTNILVRSIGAVVEPGESIMG
IVPQDGALIIETRIAPKDIAFVHTGLQATVKFTAYDFVIYGGLKGEVIYVSPDAQQLDDGTTYFEAHIKTEENVLNGWPI
ISGMQASTDILTGEKTVLNYWLKPLLRAKANALREP

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47695; Mature: 47564

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRLHIKHLEGAKRANQLIFLVAALIVVTLVWASFAKLEEVVVGEGMVVPTLAVQQIES
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
LDGGILKQVLVREGQSVSAGEPLLLLDELRFASAYDEANIQAAALKRQKARLDAEISSVV
CCHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
IDDAASYWRDKVLIKPKAISALDVSVSTRSKAIYRSRLSQLSSQLEQSAQVIEQKVQAIE
HHHHHHHHHCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLITTQAQLSGLQLVKQEIVMTRAAVREGAVAELELLKLERDEIRLKGELSASKANGRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCCCCHH
LRAAQNQAEAEYLTVALDFLSRAEAERNEVINELNALTESIKTLADRLARTQIVSPINGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VTNILVRSIGAVVEPGESIMGIVPQDGALIIETRIAPKDIAFVHTGLQATVKFTAYDFVI
HHHHHHHHHHHHCCCCCHHEEEECCCCEEEEEECCCCCHHHHEECCCCEEEEEEEEEEEE
YGGLKGEVIYVSPDAQQLDDGTTYFEAHIKTEENVLNGWPIISGMQASTDILTGEKTVLN
ECCCCCCEEEECCCHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCHHHHH
YWLKPLLRAKANALREP
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGRLHIKHLEGAKRANQLIFLVAALIVVTLVWASFAKLEEVVVGEGMVVPTLAVQQIES
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
LDGGILKQVLVREGQSVSAGEPLLLLDELRFASAYDEANIQAAALKRQKARLDAEISSVV
CCHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
IDDAASYWRDKVLIKPKAISALDVSVSTRSKAIYRSRLSQLSSQLEQSAQVIEQKVQAIE
HHHHHHHHHCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLITTQAQLSGLQLVKQEIVMTRAAVREGAVAELELLKLERDEIRLKGELSASKANGRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCCCCHH
LRAAQNQAEAEYLTVALDFLSRAEAERNEVINELNALTESIKTLADRLARTQIVSPINGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VTNILVRSIGAVVEPGESIMGIVPQDGALIIETRIAPKDIAFVHTGLQATVKFTAYDFVI
HHHHHHHHHHHHCCCCCHHEEEECCCCEEEEEECCCCCHHHHEECCCCEEEEEEEEEEEE
YGGLKGEVIYVSPDAQQLDDGTTYFEAHIKTEENVLNGWPIISGMQASTDILTGEKTVLN
ECCCCCCEEEECCCHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCHHHHH
YWLKPLLRAKANALREP
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]