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The map label for this gene is pqqL [C]

Identifier: 157963759

GI number: 157963759

Start: 4801327

End: 4802658

Strand: Reverse

Name: pqqL [C]

Synonym: Spea_3948

Alternate gene names: 157963759

Gene position: 4802658-4801327 (Counterclockwise)

Preceding gene: 157963761

Following gene: 157963758

Centisome position: 92.81

GC content: 49.7

Gene sequence:

>1332_bases
ATGAAGCGCTATACCAAGGCATTGTTGTTGTCTATTGGTCTGCTGTTAGCAGCGCCAATGGCACAAGCGACGCAAGCTAA
AGATATTCAGAGTTTCACTTTGGATAACGGCATGAAGATAATGGTATTGGAAGACAGTTCGATACCTAACGCCAATATGT
ATCTATTTTGGAAGGTCGGATCACGTAATGAGGTGCCGGGTATTACCGGTATTTCCCACTTCTTCGAACATATGATGTTT
AACGGCTCGAAGAAATATGGGCCTAAGATGTTCGACCGCACTATGGAAGCCGCGGGCGGGGCAAACAACGCCTACACCAC
CGAAAACCTCACCGTGTATACCGACTGGTTCCCAGCCAATGCGCTGGAGACGATTTTTGATCTTGAAGCCGATCGTATCG
AGAACTTGGATATTAACGAGCAGATGGTCGAGAGTGAGCGCGGGGTCGTGGCCTCTGAACGCCTAACTGGACTGGAAAAC
TCTAACTGGCGGGTGCTGCAAGAGGAGCTCAAAGGCGCGGCCTTTAGAGCCCATCCTTATAGCTGGTCGGTAATCGGTCA
TGAATCGGATATTGCCGCTTGGACCCTTGAAGATTTAACTGAGTATCACAAGACCTATTACGCGCCGAATAACGCCGTAG
TGGTGATTGCTGGTGATGTGAAACTGGCTGAAGTAAAGCAGTTGGCCGATAAGTATTTTGCCCCCATTCCAGCACAGGCT
CCGCCGAGAGCGGTGAAGACCGTCGAGCCACTACAAAAAGGTGAGCGCCGAGTCTTTGTGCAAAAAGCCTCGGTAAGCAC
CCCTAATGTAATGCTGGGTTACCATATCCCCGCAACTTCAAATGCGGACTATTACGCGCTGGATCTATTGTCATCAATCT
TGACCACAGGTAACAGCTCGCGCATGTATCAGGGCTTAGTCGATAAGCAAGTCGCGATTCAAGTCGACACCTATATGCCA
ATGTCTTTCGATCCGAATCTGTTTTACGTTATGGGCGTGGCTAATCCTGGGGTAACGGCTCCCGAGTTAGAAGATGCGAT
GATCAGCGAGATCAACCGTGTTGCCCGTGACGGCGTTACGGTCGAGGAGCTTGAGAAGGTGAAAAATATCAAGCTGATGG
GCTTTTATCGAGCCATGGAAACCATTAACGGCAAGGCTAATACCATAGGCACCTACGAGCTGTTCTTTGGCAGCTTTGAC
AAGCTATTTAATGCGCCAGAGGCTTACAACAAGGTGACACCGGAAGATATTCAGCGCGTGGCACAAACTTACCTAAAACG
TGCAAACCGTACTGTTGCCGTGCTGGCTGCAACCGAGGAGGCTGACCAATGA

Upstream 100 bases:

>100_bases
GAGTAACACCAGTTTTCAGCCACAACCAAAATACACTATTCGCCATGCTCTGACTGGAATAGATTAGAGATGGCAAGGGT
GCTTAAACAAGGAGCGGAAA

Downstream 100 bases:

>100_bases
AAACTCAGATCGCAAGGTTGATGCAACCCAAAAAATTACTGACGGCAATGGCCGTTGCCAGTTCGCTGGCATTAGCGGGC
TGTGCGGCAACGCAGACCTC

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKRYTKALLLSIGLLLAAPMAQATQAKDIQSFTLDNGMKIMVLEDSSIPNANMYLFWKVGSRNEVPGITGISHFFEHMMF
NGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPANALETIFDLEADRIENLDINEQMVESERGVVASERLTGLEN
SNWRVLQEELKGAAFRAHPYSWSVIGHESDIAAWTLEDLTEYHKTYYAPNNAVVVIAGDVKLAEVKQLADKYFAPIPAQA
PPRAVKTVEPLQKGERRVFVQKASVSTPNVMLGYHIPATSNADYYALDLLSSILTTGNSSRMYQGLVDKQVAIQVDTYMP
MSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVTVEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSFD
KLFNAPEAYNKVTPEDIQRVAQTYLKRANRTVAVLAATEEADQ

Sequences:

>Translated_443_residues
MKRYTKALLLSIGLLLAAPMAQATQAKDIQSFTLDNGMKIMVLEDSSIPNANMYLFWKVGSRNEVPGITGISHFFEHMMF
NGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPANALETIFDLEADRIENLDINEQMVESERGVVASERLTGLEN
SNWRVLQEELKGAAFRAHPYSWSVIGHESDIAAWTLEDLTEYHKTYYAPNNAVVVIAGDVKLAEVKQLADKYFAPIPAQA
PPRAVKTVEPLQKGERRVFVQKASVSTPNVMLGYHIPATSNADYYALDLLSSILTTGNSSRMYQGLVDKQVAIQVDTYMP
MSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVTVEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSFD
KLFNAPEAYNKVTPEDIQRVAQTYLKRANRTVAVLAATEEADQ
>Mature_443_residues
MKRYTKALLLSIGLLLAAPMAQATQAKDIQSFTLDNGMKIMVLEDSSIPNANMYLFWKVGSRNEVPGITGISHFFEHMMF
NGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPANALETIFDLEADRIENLDINEQMVESERGVVASERLTGLEN
SNWRVLQEELKGAAFRAHPYSWSVIGHESDIAAWTLEDLTEYHKTYYAPNNAVVVIAGDVKLAEVKQLADKYFAPIPAQA
PPRAVKTVEPLQKGERRVFVQKASVSTPNVMLGYHIPATSNADYYALDLLSSILTTGNSSRMYQGLVDKQVAIQVDTYMP
MSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVTVEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSFD
KLFNAPEAYNKVTPEDIQRVAQTYLKRANRTVAVLAATEEADQ

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=306, Percent_Identity=28.1045751633987, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI94538354, Length=219, Percent_Identity=29.2237442922374, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI155969707, Length=241, Percent_Identity=27.3858921161826, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI24308013, Length=434, Percent_Identity=23.5023041474654, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787770, Length=387, Percent_Identity=23.5142118863049, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI2367164, Length=236, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17553678, Length=230, Percent_Identity=26.9565217391304, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71999683, Length=204, Percent_Identity=28.4313725490196, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25146563, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994338, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25146566, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32566665, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533970, Length=212, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=289, Percent_Identity=24.5674740484429, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323421, Length=197, Percent_Identity=26.3959390862944, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21357875, Length=451, Percent_Identity=23.5033259423503, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24646943, Length=451, Percent_Identity=23.5033259423503, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI221513245, Length=218, Percent_Identity=24.3119266055046, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49379; Mature: 49379

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYTKALLLSIGLLLAAPMAQATQAKDIQSFTLDNGMKIMVLEDSSIPNANMYLFWKVG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCEEEEEEEC
SRNEVPGITGISHFFEHMMFNGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPAN
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEECCCEEEEECCCCCH
ALETIFDLEADRIENLDINEQMVESERGVVASERLTGLENSNWRVLQEELKGAAFRAHPY
HHHHHHHCCHHHHCCCCCCHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEECCC
SWSVIGHESDIAAWTLEDLTEYHKTYYAPNNAVVVIAGDVKLAEVKQLADKYFAPIPAQA
EEEEECCCCCCCEEEHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCC
PPRAVKTVEPLQKGERRVFVQKASVSTPNVMLGYHIPATSNADYYALDLLSSILTTGNSS
CCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCH
RMYQGLVDKQVAIQVDTYMPMSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVT
HHHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
VEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSFDKLFNAPEAYNKVTPEDIQRV
HHHHHHHHCCEEHHHHHHHHHCCCCCCCEEEHHHHHCCHHHHCCCCHHHCCCCHHHHHHH
AQTYLKRANRTVAVLAATEEADQ
HHHHHHHCCCEEEEEEECCCCCC
>Mature Secondary Structure
MKRYTKALLLSIGLLLAAPMAQATQAKDIQSFTLDNGMKIMVLEDSSIPNANMYLFWKVG
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCEEEEEECCCCCCCCEEEEEEEC
SRNEVPGITGISHFFEHMMFNGSKKYGPKMFDRTMEAAGGANNAYTTENLTVYTDWFPAN
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEECCCEEEEECCCCCH
ALETIFDLEADRIENLDINEQMVESERGVVASERLTGLENSNWRVLQEELKGAAFRAHPY
HHHHHHHCCHHHHCCCCCCHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCEEEECCC
SWSVIGHESDIAAWTLEDLTEYHKTYYAPNNAVVVIAGDVKLAEVKQLADKYFAPIPAQA
EEEEECCCCCCCEEEHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCC
PPRAVKTVEPLQKGERRVFVQKASVSTPNVMLGYHIPATSNADYYALDLLSSILTTGNSS
CCHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCH
RMYQGLVDKQVAIQVDTYMPMSFDPNLFYVMGVANPGVTAPELEDAMISEINRVARDGVT
HHHHHHCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCC
VEELEKVKNIKLMGFYRAMETINGKANTIGTYELFFGSFDKLFNAPEAYNKVTPEDIQRV
HHHHHHHHCCEEHHHHHHHHHCCCCCCCEEEHHHHHCCHHHHCCCCHHHCCCCHHHHHHH
AQTYLKRANRTVAVLAATEEADQ
HHHHHHHCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]