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The map label for this gene is yqhD [H]

Identifier: 157963736

GI number: 157963736

Start: 4773308

End: 4774465

Strand: Direct

Name: yqhD [H]

Synonym: Spea_3925

Alternate gene names: 157963736

Gene position: 4773308-4774465 (Clockwise)

Preceding gene: 157963735

Following gene: 157963737

Centisome position: 92.25

GC content: 47.93

Gene sequence:

>1158_bases
ATGTACAGCTTCGATTATTACAACCCAACTCATATCTGTTTCGGTGAAGGCAAGATTGCCGAACTCGATAACTTAGTCCC
ACCGGACGCAAAAGTCTTAGTGCTTTTTGGCGGCAACAGCGCCAGAAGCACAGGCACACTCGACGAGGTAAAAGCTGCGC
TTAAGCAACGTAATGTCGTGGAATTTGGTGGAATCGAGGCGAATCCGACCTACGAAACCTTGATGCAAGCGGTCGAGGTG
GTAAAACAGCAAAATATCGACTTTCTACTAGCTGTCGGTGGCGGCTCGGTTATCGATGGCACTAAGTTTGTCGCGGCGGC
TACGCTCTTTGAAGGCGAGCCATGGGATATCCTATTAAGCTGGGGTGCAAACGTCACCCAGGCGATGCCCTTCGGTACAG
TATTAACCTTGCCTGCTACCGGCTCAGAGATGAACAGTGCCAGCGTCGTCACTCGTAAATCGTTACAGGCAAAACTGTCT
TTTATGAGTAACCATGTCTTTCCAAAATTCTCAGTATTGGATCCAAGCAAAACCTTCACCTTACCTGAGCGTCAAGTGGC
TAACGGCGTAGTCGATGCCTTTATCCATATTACAGAGCAATATCTAAACTACCCAGTTAATGCACCAGTGCAAGACAGAT
TTGCCGAAGGCCTACTGCAAACATTAATCGAGTTAGGGCCAAAAGCTTTAAGCGAGCCAAAAGATTTCGACGTGCGCGCA
AACCTTATGTGGGTGGCGGCCATGGCACTGAGTGGCGTAATCGGTAAAGGAGTACCACACGACTGGGCAACGCATATGAT
AGGCCATGAGATCACCGTGCTTTATGGTGTCGACCATGCCCGAACTATTGCAATGATTTTGCCTGGCATGCTCGATGTAC
GCCGTGAGGGTAAGCAAGAGAAGCTATTGCAATATGCCGATCGCGTCTGGGGCATTAACCAGGGTAGCAAGGATGAGATC
ATCGATGAAGCTATCGAAAAGACCCGTGAATTTTTCGAGGCCATGGGGATCAAGACACGCTTATCGGATTACGATTTAGA
TAGCAGCAGTATCAATGAGATAATTAATAAACTTGAAGCCCACGGCATGACAGCACTGGGTGAAAAGCAAGATGTCGATC
TTGCCATGAGCCGTAAAATTTTAGAACGTAACCTATAA

Upstream 100 bases:

>100_bases
CAATCACTAGGCCTTAAGTAACAGCACTATGATCCACACAAGCATCCATACAAGAATTCACACAAGAGTCGGCTGATAGA
GTCGACAGGCAGGAAAGATC

Downstream 100 bases:

>100_bases
ATCTACATTATCACCAAGATAAAAACTGTATAAGAGACCTCAGCTAGCTAACCGGTGTATCTCGCTTGTTAGCTGGCAAA
TCAACAGATAAAAAGGACAA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MYSFDYYNPTHICFGEGKIAELDNLVPPDAKVLVLFGGNSARSTGTLDEVKAALKQRNVVEFGGIEANPTYETLMQAVEV
VKQQNIDFLLAVGGGSVIDGTKFVAAATLFEGEPWDILLSWGANVTQAMPFGTVLTLPATGSEMNSASVVTRKSLQAKLS
FMSNHVFPKFSVLDPSKTFTLPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSEPKDFDVRA
NLMWVAAMALSGVIGKGVPHDWATHMIGHEITVLYGVDHARTIAMILPGMLDVRREGKQEKLLQYADRVWGINQGSKDEI
IDEAIEKTREFFEAMGIKTRLSDYDLDSSSINEIINKLEAHGMTALGEKQDVDLAMSRKILERNL

Sequences:

>Translated_385_residues
MYSFDYYNPTHICFGEGKIAELDNLVPPDAKVLVLFGGNSARSTGTLDEVKAALKQRNVVEFGGIEANPTYETLMQAVEV
VKQQNIDFLLAVGGGSVIDGTKFVAAATLFEGEPWDILLSWGANVTQAMPFGTVLTLPATGSEMNSASVVTRKSLQAKLS
FMSNHVFPKFSVLDPSKTFTLPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSEPKDFDVRA
NLMWVAAMALSGVIGKGVPHDWATHMIGHEITVLYGVDHARTIAMILPGMLDVRREGKQEKLLQYADRVWGINQGSKDEI
IDEAIEKTREFFEAMGIKTRLSDYDLDSSSINEIINKLEAHGMTALGEKQDVDLAMSRKILERNL
>Mature_385_residues
MYSFDYYNPTHICFGEGKIAELDNLVPPDAKVLVLFGGNSARSTGTLDEVKAALKQRNVVEFGGIEANPTYETLMQAVEV
VKQQNIDFLLAVGGGSVIDGTKFVAAATLFEGEPWDILLSWGANVTQAMPFGTVLTLPATGSEMNSASVVTRKSLQAKLS
FMSNHVFPKFSVLDPSKTFTLPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSEPKDFDVRA
NLMWVAAMALSGVIGKGVPHDWATHMIGHEITVLYGVDHARTIAMILPGMLDVRREGKQEKLLQYADRVWGINQGSKDEI
IDEAIEKTREFFEAMGIKTRLSDYDLDSSSINEIINKLEAHGMTALGEKQDVDLAMSRKILERNL

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=252, Percent_Identity=24.2063492063492, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789386, Length=384, Percent_Identity=58.0729166666667, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI48994951, Length=308, Percent_Identity=25, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082107, Length=289, Percent_Identity=25.9515570934256, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=289, Percent_Identity=24.2214532871972, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321181, Length=322, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24657991, Length=357, Percent_Identity=22.6890756302521, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42381; Mature: 42381

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSFDYYNPTHICFGEGKIAELDNLVPPDAKVLVLFGGNSARSTGTLDEVKAALKQRNVV
CCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCE
EFGGIEANPTYETLMQAVEVVKQQNIDFLLAVGGGSVIDGTKFVAAATLFEGEPWDILLS
EECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHCCCCCCEEEEE
WGANVTQAMPFGTVLTLPATGSEMNSASVVTRKSLQAKLSFMSNHVFPKFSVLDPSKTFT
CCCCHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
LPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSEPKDFDVRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHH
NLMWVAAMALSGVIGKGVPHDWATHMIGHEITVLYGVDHARTIAMILPGMLDVRREGKQE
HHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCHHH
KLLQYADRVWGINQGSKDEIIDEAIEKTREFFEAMGIKTRLSDYDLDSSSINEIINKLEA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHH
HGMTALGEKQDVDLAMSRKILERNL
CCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYSFDYYNPTHICFGEGKIAELDNLVPPDAKVLVLFGGNSARSTGTLDEVKAALKQRNVV
CCCCCCCCCCEEEECCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCE
EFGGIEANPTYETLMQAVEVVKQQNIDFLLAVGGGSVIDGTKFVAAATLFEGEPWDILLS
EECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHCCCCCCEEEEE
WGANVTQAMPFGTVLTLPATGSEMNSASVVTRKSLQAKLSFMSNHVFPKFSVLDPSKTFT
CCCCHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCC
LPERQVANGVVDAFIHITEQYLNYPVNAPVQDRFAEGLLQTLIELGPKALSEPKDFDVRA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHH
NLMWVAAMALSGVIGKGVPHDWATHMIGHEITVLYGVDHARTIAMILPGMLDVRREGKQE
HHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCHHH
KLLQYADRVWGINQGSKDEIIDEAIEKTREFFEAMGIKTRLSDYDLDSSSINEIINKLEA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHH
HGMTALGEKQDVDLAMSRKILERNL
CCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]