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The map label for this gene is fabF [H]

Identifier: 157963714

GI number: 157963714

Start: 4749939

End: 4751186

Strand: Direct

Name: fabF [H]

Synonym: Spea_3903

Alternate gene names: 157963714

Gene position: 4749939-4751186 (Clockwise)

Preceding gene: 157963713

Following gene: 157963715

Centisome position: 91.79

GC content: 53.04

Gene sequence:

>1248_bases
ATGAGCCAAGCGTCTTTTCCCCGTCGCGTCGTGATCACAGGTATTGGCGGTATTTCGGCTCTAGGGCATGACTGGCCAAC
GATTGCTGAGAGCTTAAAAGCGAAAAAGAACTGTGTAGTGCGTATGGATGAATGGGACAGATTTGAAGATCTACACACCC
GTTTAGCCGCGCCCATTACCGACTTTGAAGTGCCGAGCCATTACAAACGTAAAAAGATCCGCTCCATGGGCCGCGTATCT
ATTATGGCCACCCGTGCCAGTGAACTGGCACTGATAGATGCTAACCTGCTTGATGATCCTGTGGTCACCTCTGGCGCCAT
GGGCATAGCCTACGGCTCATCGACTGGCAGCACGGATCCAATTGTTGCCTTTGGCGACATGCTTAAAGACGGTGATATGT
CGGGTGTTACCGCCACCAGCTATATCCGCATGATGGCCCATACAACGGCGGTGAACGTCGGTGTATTCTTCGGGCTCAAG
GGCCGAGTGCACACCACCAGCAGCGCTTGTACCTCAGGTAGCCAAGGCATAGGTTACGCCTATGAAGCCATCAAGTATGG
TCAGCAAGACCTCATGCTTGCCGGCGGCGGTGAGGAGCTTTGCCCAACAGAGGCGGTAGTCTTCGACACCCTGTTTGCTA
CCAGCACCAAAAATGATACGCCAGCGCAGACACCACGCCCGTTCGATAAAAACCGTGACGGTCTAGTAATAGGCGAAGGC
GCTTGTACATTAGTGCTAGAGGAGCTGGAACATGCTAGAGCTCGCGGCGCCAAGATCTACGCCGAAATCGTCGGCTTTGG
CACGAATGCCGACGGTCTTCATGTGACTCAGCCTAATAGCGCGACCATGGAAACTGCAATTCGTTTAGCGCTGAAAGATG
CCGCCATCGACGCTGAAAAAGTAGGTTATGTGAATGCCCACGGCACCGCGACCGACCGCGGCGATATTGCCGAGACACAA
GCGACCCACGCGGTATTTGGCCCTTCTCAGCCTATCTCGTCGCTCAAGAGCTACACTGGCCATACGCTGGGAGCCTGCGG
CGCGTTAGAGGCCTGGGTCAGCATTGAGATGATGAATGAAGGCTGGTTCGCACCCACGCTAAATCTCAGCGAAATCGATG
AAGAATGTGGAGAACTGGATTACATCAAAGATGAAGTCCGCTTGCTTGAAACTGACTATGTGATGAGTAATAACTTCGCC
TTCGGTGGCATCAATACCTCGCTGATCTTTAAGCGGTTTAAAAGATAG

Upstream 100 bases:

>100_bases
TGGGTAAGCCATCTGAAATTGCAGGTTTGGCCAATTACTTGATGTCAGAAGATGCCGCCTATATCACTCGCCAAGTGATC
TCGGTTAATGGAGGCATGAT

Downstream 100 bases:

>100_bases
GCTCTAGGAATAGAAGGTGCTAGGTCCTAGGAAATGCTAAGAAAGGTCCTAGGGAAAGCAAAGACGAACGTGACTAGGTC
ACTTACGGAACGCTTCGCTT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSQASFPRRVVITGIGGISALGHDWPTIAESLKAKKNCVVRMDEWDRFEDLHTRLAAPITDFEVPSHYKRKKIRSMGRVS
IMATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDPIVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLK
GRVHTTSSACTSGSQGIGYAYEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPAQTPRPFDKNRDGLVIGEG
ACTLVLEELEHARARGAKIYAEIVGFGTNADGLHVTQPNSATMETAIRLALKDAAIDAEKVGYVNAHGTATDRGDIAETQ
ATHAVFGPSQPISSLKSYTGHTLGACGALEAWVSIEMMNEGWFAPTLNLSEIDEECGELDYIKDEVRLLETDYVMSNNFA
FGGINTSLIFKRFKR

Sequences:

>Translated_415_residues
MSQASFPRRVVITGIGGISALGHDWPTIAESLKAKKNCVVRMDEWDRFEDLHTRLAAPITDFEVPSHYKRKKIRSMGRVS
IMATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDPIVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLK
GRVHTTSSACTSGSQGIGYAYEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPAQTPRPFDKNRDGLVIGEG
ACTLVLEELEHARARGAKIYAEIVGFGTNADGLHVTQPNSATMETAIRLALKDAAIDAEKVGYVNAHGTATDRGDIAETQ
ATHAVFGPSQPISSLKSYTGHTLGACGALEAWVSIEMMNEGWFAPTLNLSEIDEECGELDYIKDEVRLLETDYVMSNNFA
FGGINTSLIFKRFKR
>Mature_414_residues
SQASFPRRVVITGIGGISALGHDWPTIAESLKAKKNCVVRMDEWDRFEDLHTRLAAPITDFEVPSHYKRKKIRSMGRVSI
MATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDPIVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLKG
RVHTTSSACTSGSQGIGYAYEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPAQTPRPFDKNRDGLVIGEGA
CTLVLEELEHARARGAKIYAEIVGFGTNADGLHVTQPNSATMETAIRLALKDAAIDAEKVGYVNAHGTATDRGDIAETQA
THAVFGPSQPISSLKSYTGHTLGACGALEAWVSIEMMNEGWFAPTLNLSEIDEECGELDYIKDEVRLLETDYVMSNNFAF
GGINTSLIFKRFKR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=33.3333333333333, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI41872631, Length=281, Percent_Identity=30.2491103202847, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI223972627, Length=162, Percent_Identity=35.1851851851852, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1787337, Length=420, Percent_Identity=37.8571428571429, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1788663, Length=412, Percent_Identity=36.1650485436893, Blast_Score=235, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=32.289156626506, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71983535, Length=265, Percent_Identity=38.1132075471698, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI212642053, Length=348, Percent_Identity=27.8735632183908, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17550940, Length=265, Percent_Identity=27.5471698113208, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=444, Percent_Identity=32.2072072072072, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24644341, Length=428, Percent_Identity=34.8130841121495, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI221330659, Length=358, Percent_Identity=25.9776536312849, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19920632, Length=358, Percent_Identity=25.9776536312849, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24581345, Length=338, Percent_Identity=25.1479289940828, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44647; Mature: 44516

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQASFPRRVVITGIGGISALGHDWPTIAESLKAKKNCVVRMDEWDRFEDLHTRLAAPIT
CCCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCC
DFEVPSHYKRKKIRSMGRVSIMATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDP
CCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCC
IVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLKGRVHTTSSACTSGSQGIGYA
EEEEHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCEEECCHHHCCCCCCCHHH
YEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPAQTPRPFDKNRDGLVIGEG
HHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECC
ACTLVLEELEHARARGAKIYAEIVGFGTNADGLHVTQPNSATMETAIRLALKDAAIDAEK
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHH
VGYVNAHGTATDRGDIAETQATHAVFGPSQPISSLKSYTGHTLGACGALEAWVSIEMMNE
CCEEECCCCCCCCCCCHHHHCCCEECCCCHHHHHHHHHCCCCHHHHHHHHHHEEEEEECC
GWFAPTLNLSEIDEECGELDYIKDEVRLLETDYVMSNNFAFGGINTSLIFKRFKR
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCEEEECCEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
SQASFPRRVVITGIGGISALGHDWPTIAESLKAKKNCVVRMDEWDRFEDLHTRLAAPIT
CCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCC
DFEVPSHYKRKKIRSMGRVSIMATRASELALIDANLLDDPVVTSGAMGIAYGSSTGSTDP
CCCCCCHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCC
IVAFGDMLKDGDMSGVTATSYIRMMAHTTAVNVGVFFGLKGRVHTTSSACTSGSQGIGYA
EEEEHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCCEEECCHHHCCCCCCCHHH
YEAIKYGQQDLMLAGGGEELCPTEAVVFDTLFATSTKNDTPAQTPRPFDKNRDGLVIGEG
HHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECC
ACTLVLEELEHARARGAKIYAEIVGFGTNADGLHVTQPNSATMETAIRLALKDAAIDAEK
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHH
VGYVNAHGTATDRGDIAETQATHAVFGPSQPISSLKSYTGHTLGACGALEAWVSIEMMNE
CCEEECCCCCCCCCCCHHHHCCCEECCCCHHHHHHHHHCCCCHHHHHHHHHHEEEEEECC
GWFAPTLNLSEIDEECGELDYIKDEVRLLETDYVMSNNFAFGGINTSLIFKRFKR
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCEEEECCEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]