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The map label for this gene is recG [H]

Identifier: 157963695

GI number: 157963695

Start: 4730762

End: 4732852

Strand: Direct

Name: recG [H]

Synonym: Spea_3884

Alternate gene names: 157963695

Gene position: 4730762-4732852 (Clockwise)

Preceding gene: 157963694

Following gene: 157963696

Centisome position: 91.42

GC content: 50.45

Gene sequence:

>2091_bases
TTGAGTGCTAACAGTTTGCAAAGACTCGATCTTGTTCCTATCACAGATCTCAAAGGCGTCGCGAAGAAGATGGCCGAGAG
ACTAGCTAAGTTGAGCATAACAACAGTGCAAGATCTGTTGTTTCATCTGCCGCTGCGCTACGAGGATCGCACTCAAGTCT
ATCCTATTGCCTCGCTTTATCCCGGCAGTTACGGCACCATCGAAGCCATTATTCAGTCGAGCCAAATTATTCAAGGCCGC
AAGCGCATGCTCACCTGCACCGTGCGCGATGATACTGGCAGCTTAACCCTAAGGTTTTTTAACTTCTCTGTTGCCCAGCG
TAACGGCTTAGAGATAGGCATGACTATTAGAGCCTACGGTGAAATACGCCGCAGTAATCACGGCGTTGAAATTATTCATC
CAGAATACAAGCTCATCTCACCGGGTGAAGACCTACAGCTAAGCGATACGCTGACCCCTGTCTACCCAACCACCGAGGGC
TTAAAGCAAGCCAGTTGGATTAAGCTCACCGAGCAAGCACTCGCTATGCTAGACAATGGTGGCTTACAGGAACTGCTGCC
CACTAACCTGCAGCCAAATAATTTAGATTTAAAACAAGCGCTACAGATCTTACATAGGCCCAATAATCAGGTTTCACTTT
TCGAGCTGGAGCAAGGTACGCATCCGGCGCAGCAACGTCTTATCCAAGAAGAGTTACTGGCTCACAATCTGAGCATGTTA
CGACTGCGCCAGCGCAGCAACCGTGATAGCGCGGTCAGTATGAATGCCACGGGTCAGCTACTGAATCCATTTTTAGCCTC
TTTGCCCTTTAAGCCTACGGGCGCACAGCAGCGAGTTGTCGCCGACATCACCCAAGACTTGGCCAAGCACGAGCCAATGA
TGCGATTGGTACAAGGCGATGTGGGCTCAGGTAAAACCTTGGTCGCCGCCTTAGCTGCACTGCAGGCAATAGAGAGCGGC
TATCAAGTAGCAATGATGGCACCAACAGAATTACTAGCCGAGCAACACGCAATCAATTTCAAGAGCTGGTTTGAGCCTTT
AGGGCTAAAAGTCGGCTGGCTTGCAGGAAAACTCAAAGGCAAGGCCAGAGCCCAGTCATTAGCCGATATAGAATCTGGCG
ATGCCCATATTGTGATTGGCACCCATGCTATTTTCCAAGAGCAGGTACAGTTTAATAAATTAGCGCTGATTATCATCGAT
GAGCAACATAGATTTGGCGTACACCAACGCTTAGGTCTGCGTGAAAAAGGCATTAGTCAGGGCTTTCATCCACACCAGTT
GATTATGACGGCAACCCCGATCCCGCGTACTTTGGCGATGACCGCCTATGCCGATCTCGACACCTCTATTATCGATGAGT
TGCCGCCAGGAAGAACCCCGGTAACCACAGTGGCTATTTCCGAACAACGCCGCGAAGAGGTCCTCGAGCGTGTCCGTCAG
GCAGCAATTAACGACAAACGCCAAGCCTATTGGGTTTGCACCTTAATTGAAGAGTCTGAAGCCCTCGAATGTCAGGCTGC
TGAAGATACGGCAGAAGAACTTAAACGTGCTCTGCCCGAGTTAAAAGTTGGCCTAGTGCATGGCCGTATGAAGCCCGCTG
AGAAGCAGCAGATCATGGCAGATTTCAAAGCCGGAGAACTCAACCTGCTGGTTGCTACGACCGTGATTGAGGTTGGAGTC
GATGTGCCCAATGCCAGCTTGATGATCATTGAAAACCCTGAACGTTTGGGCCTAGCCCAGCTGCACCAACTTAGAGGTCG
TGTGGGTCGTGGCGCGGTAGCCAGTCACTGCGTGCTGTTATACAAGGCACCATTATCGGCAACGGCAACCAAGCGGATTG
GGGTACTGAGACAAAGTAATGATGGCTTTGTTATTGCCCAGCAAGATCTGGAGATCCGTGGCCCTGGCGAAGTACTAGGC
ACCAAGCAAACCGGTATTGCCGACATGAAAATTGCCGACTTGATGCGCGATCAGGCGCTCATTCCCCATATACAGAAACT
GGCAGCTCACGTTATGCAGCAAGCACCAAATAGTGTCGATGCCATTATTGAGCGCTGGTTAGGCGATAGAGAGCAGTTTG
TACAAGCGTAA

Upstream 100 bases:

>100_bases
CACCCAGCCCACATTAATTAGCTGCTTGACTCCCAAACCAATAAACGCCAAATTTGCGTAAACCGATAACTCTGATAATA
TATGTATAAATTTACAGTGT

Downstream 100 bases:

>100_bases
AGTGCTAATTTGAGCCGTTTTCCAAATTAAATATCCTTCATAGAGGCTTAGCCTATAGACAATCCGTTGGAATATTGCAA
AATGGATTAAAGCTATACTT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MSANSLQRLDLVPITDLKGVAKKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLYPGSYGTIEAIIQSSQIIQGR
KRMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYGEIRRSNHGVEIIHPEYKLISPGEDLQLSDTLTPVYPTTEG
LKQASWIKLTEQALAMLDNGGLQELLPTNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSML
RLRQRSNRDSAVSMNATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGDVGSGKTLVAALAALQAIESG
YQVAMMAPTELLAEQHAINFKSWFEPLGLKVGWLAGKLKGKARAQSLADIESGDAHIVIGTHAIFQEQVQFNKLALIIID
EQHRFGVHQRLGLREKGISQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRREEVLERVRQ
AAINDKRQAYWVCTLIEESEALECQAAEDTAEELKRALPELKVGLVHGRMKPAEKQQIMADFKAGELNLLVATTVIEVGV
DVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKAPLSATATKRIGVLRQSNDGFVIAQQDLEIRGPGEVLG
TKQTGIADMKIADLMRDQALIPHIQKLAAHVMQQAPNSVDAIIERWLGDREQFVQA

Sequences:

>Translated_696_residues
MSANSLQRLDLVPITDLKGVAKKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLYPGSYGTIEAIIQSSQIIQGR
KRMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYGEIRRSNHGVEIIHPEYKLISPGEDLQLSDTLTPVYPTTEG
LKQASWIKLTEQALAMLDNGGLQELLPTNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSML
RLRQRSNRDSAVSMNATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGDVGSGKTLVAALAALQAIESG
YQVAMMAPTELLAEQHAINFKSWFEPLGLKVGWLAGKLKGKARAQSLADIESGDAHIVIGTHAIFQEQVQFNKLALIIID
EQHRFGVHQRLGLREKGISQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRREEVLERVRQ
AAINDKRQAYWVCTLIEESEALECQAAEDTAEELKRALPELKVGLVHGRMKPAEKQQIMADFKAGELNLLVATTVIEVGV
DVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKAPLSATATKRIGVLRQSNDGFVIAQQDLEIRGPGEVLG
TKQTGIADMKIADLMRDQALIPHIQKLAAHVMQQAPNSVDAIIERWLGDREQFVQA
>Mature_695_residues
SANSLQRLDLVPITDLKGVAKKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLYPGSYGTIEAIIQSSQIIQGRK
RMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYGEIRRSNHGVEIIHPEYKLISPGEDLQLSDTLTPVYPTTEGL
KQASWIKLTEQALAMLDNGGLQELLPTNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSMLR
LRQRSNRDSAVSMNATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGDVGSGKTLVAALAALQAIESGY
QVAMMAPTELLAEQHAINFKSWFEPLGLKVGWLAGKLKGKARAQSLADIESGDAHIVIGTHAIFQEQVQFNKLALIIIDE
QHRFGVHQRLGLREKGISQGFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRREEVLERVRQA
AINDKRQAYWVCTLIEESEALECQAAEDTAEELKRALPELKVGLVHGRMKPAEKQQIMADFKAGELNLLVATTVIEVGVD
VPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKAPLSATATKRIGVLRQSNDGFVIAQQDLEIRGPGEVLGT
KQTGIADMKIADLMRDQALIPHIQKLAAHVMQQAPNSVDAIIERWLGDREQFVQA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=688, Percent_Identity=66.7151162790698, Blast_Score=911, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=387, Percent_Identity=38.5012919896641, Blast_Score=242, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6320224, Length=373, Percent_Identity=24.1286863270777, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77016; Mature: 76885

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANSLQRLDLVPITDLKGVAKKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLY
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHCC
PGSYGTIEAIIQSSQIIQGRKRMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYG
CCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEEEECCCCCCEEEEEEEEHH
EIRRSNHGVEIIHPEYKLISPGEDLQLSDTLTPVYPTTEGLKQASWIKLTEQALAMLDNG
HHHHCCCCEEEECCCEEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GLQELLPTNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSML
CHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
RLRQRSNRDSAVSMNATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGD
HHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
VGSGKTLVAALAALQAIESGYQVAMMAPTELLAEQHAINFKSWFEPLGLKVGWLAGKLKG
CCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHCCEEEEHHHHHCC
KARAQSLADIESGDAHIVIGTHAIFQEQVQFNKLALIIIDEQHRFGVHQRLGLREKGISQ
HHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCEEEEEEEECCHHCCHHHHCCCHHHHHCC
GFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRREEVLERVRQ
CCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHH
AAINDKRQAYWVCTLIEESEALECQAAEDTAEELKRALPELKVGLVHGRMKPAEKQQIMA
HHCCCCCCEEEEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
DFKAGELNLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLL
HCCCCCEEEEEEEEHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHEEEE
YKAPLSATATKRIGVLRQSNDGFVIAQQDLEIRGPGEVLGTKQTGIADMKIADLMRDQAL
EECCCCHHHHHHHHEEEECCCCEEEEECCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
IPHIQKLAAHVMQQAPNSVDAIIERWLGDREQFVQA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure 
SANSLQRLDLVPITDLKGVAKKMAERLAKLSITTVQDLLFHLPLRYEDRTQVYPIASLY
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHCC
PGSYGTIEAIIQSSQIIQGRKRMLTCTVRDDTGSLTLRFFNFSVAQRNGLEIGMTIRAYG
CCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEEEECCCCCCEEEEEEEEHH
EIRRSNHGVEIIHPEYKLISPGEDLQLSDTLTPVYPTTEGLKQASWIKLTEQALAMLDNG
HHHHCCCCEEEECCCEEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GLQELLPTNLQPNNLDLKQALQILHRPNNQVSLFELEQGTHPAQQRLIQEELLAHNLSML
CHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
RLRQRSNRDSAVSMNATGQLLNPFLASLPFKPTGAQQRVVADITQDLAKHEPMMRLVQGD
HHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
VGSGKTLVAALAALQAIESGYQVAMMAPTELLAEQHAINFKSWFEPLGLKVGWLAGKLKG
CCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHCCEEEEHHHHHCC
KARAQSLADIESGDAHIVIGTHAIFQEQVQFNKLALIIIDEQHRFGVHQRLGLREKGISQ
HHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCEEEEEEEECCHHCCHHHHCCCHHHHHCC
GFHPHQLIMTATPIPRTLAMTAYADLDTSIIDELPPGRTPVTTVAISEQRREEVLERVRQ
CCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHH
AAINDKRQAYWVCTLIEESEALECQAAEDTAEELKRALPELKVGLVHGRMKPAEKQQIMA
HHCCCCCCEEEEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
DFKAGELNLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLL
HCCCCCEEEEEEEEHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHEEEE
YKAPLSATATKRIGVLRQSNDGFVIAQQDLEIRGPGEVLGTKQTGIADMKIADLMRDQAL
EECCCCHHHHHHHHEEEECCCCEEEEECCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
IPHIQKLAAHVMQQAPNSVDAIIERWLGDREQFVQA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]