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The map label for this gene is yrbG [H]

Identifier: 157963694

GI number: 157963694

Start: 4729636

End: 4730559

Strand: Direct

Name: yrbG [H]

Synonym: Spea_3883

Alternate gene names: 157963694

Gene position: 4729636-4730559 (Clockwise)

Preceding gene: 157963693

Following gene: 157963695

Centisome position: 91.4

GC content: 46.86

Gene sequence:

>924_bases
ATGTTTATTTTATTGTCGATACTCGGCGGCTTTTTAATTCTGACCATAGGCGCAGAAGCCTTAGTTAGAGGTGCAAGCCA
AATCGCACTTAGATTGGGGCTTACGCCTCTTATCATCGGCCTAACAATCGTTGCCTTTGGTACCAGTGCTCCTGAACTTG
CGGTTAGCGTAAAATCAGCAATTGCAGGCAATAGCGGCATCGCCTTAGGTAACGTGATTGGCTCAAACATCGCCAACATC
GGCCTGATTTTAGGTATCACAGCGCTTATTCGCCCGATTAAGATCGAGTCACAAATGGTACGCCGTGATATTCCAATCAT
GATTGGTGCATCGCTACTGTTCTGGAGCCTGCTACTTGATGGCGGCTTAAGCTTCTGGGATGGCGCAATTCTATTTGCAC
TACTTGTGGCTTACTTAACCTTTAGCTATTTCACTGCCGAAAAGCAGACTGACGATGATGTAGAAGATACCAAGCAAAAC
CCTATGCTATCTGTGCTATTTATCGTTATCGGTATCAGCATGCTAGTGGGCGGCGGGATCTTATTCGTTGATGGCGCAGT
GGCTATGGCGAAATCATTCGGCATTAGCGAAGTGATTATCGGCCTAACTATCGTGGCTATCGGTACCAGCATGCCAGAAC
TTGTTACCTCGGTTGTGGCAGCGCTTAAAGGTCAGAGCGATATCGCGATTGGTAACGTGGTTGGCTCAAACCTGTTCAAT
ATTCTAGGTATTTTGGGCGTTACCGCACTTATCCACCCGATTGTTGGCAGCGAAATTAGTACGCTAGACTGGATTTCAAT
GATTGCCTTTGCAATGATCTTACTGCCGTTTGCCTACACGGGTTTACGCATCGGTCGCCGTGAAGCAGCTCTGTTAGTAC
TAGGTTACCTAGTGTACATTGGCTACCTGGTTGCTCAAGTTTAA

Upstream 100 bases:

>100_bases
AACTAAATTTAATGACTAAGAAGCAGTTTTCTATTGCGCAATTTTTGAAAGAAACTATTCTTGCCATCCTTTCAGAAACA
TCCAATTTATAGAGTTAATC

Downstream 100 bases:

>100_bases
TCCTGAAGTAACTCGATAGAAAAGGCCTAAATTGCAGTCGCAGTTTAGGCCTTTTTTGTGGCAGTCTATCCCGAGTCTGC
TGACATGCTTCACGACTGTC

Product: CaCA family Na(+)/Ca(+) antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MFILLSILGGFLILTIGAEALVRGASQIALRLGLTPLIIGLTIVAFGTSAPELAVSVKSAIAGNSGIALGNVIGSNIANI
GLILGITALIRPIKIESQMVRRDIPIMIGASLLFWSLLLDGGLSFWDGAILFALLVAYLTFSYFTAEKQTDDDVEDTKQN
PMLSVLFIVIGISMLVGGGILFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSVVAALKGQSDIAIGNVVGSNLFN
ILGILGVTALIHPIVGSEISTLDWISMIAFAMILLPFAYTGLRIGRREAALLVLGYLVYIGYLVAQV

Sequences:

>Translated_307_residues
MFILLSILGGFLILTIGAEALVRGASQIALRLGLTPLIIGLTIVAFGTSAPELAVSVKSAIAGNSGIALGNVIGSNIANI
GLILGITALIRPIKIESQMVRRDIPIMIGASLLFWSLLLDGGLSFWDGAILFALLVAYLTFSYFTAEKQTDDDVEDTKQN
PMLSVLFIVIGISMLVGGGILFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSVVAALKGQSDIAIGNVVGSNLFN
ILGILGVTALIHPIVGSEISTLDWISMIAFAMILLPFAYTGLRIGRREAALLVLGYLVYIGYLVAQV
>Mature_307_residues
MFILLSILGGFLILTIGAEALVRGASQIALRLGLTPLIIGLTIVAFGTSAPELAVSVKSAIAGNSGIALGNVIGSNIANI
GLILGITALIRPIKIESQMVRRDIPIMIGASLLFWSLLLDGGLSFWDGAILFALLVAYLTFSYFTAEKQTDDDVEDTKQN
PMLSVLFIVIGISMLVGGGILFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSVVAALKGQSDIAIGNVVGSNLFN
ILGILGVTALIHPIVGSEISTLDWISMIAFAMILLPFAYTGLRIGRREAALLVLGYLVYIGYLVAQV

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI4759128, Length=75, Percent_Identity=46.6666666666667, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789587, Length=301, Percent_Identity=37.2093023255814, Blast_Score=144, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 32093; Mature: 32093

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFILLSILGGFLILTIGAEALVRGASQIALRLGLTPLIIGLTIVAFGTSAPELAVSVKSA
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHH
IAGNSGIALGNVIGSNIANIGLILGITALIRPIKIESQMVRRDIPIMIGASLLFWSLLLD
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GGLSFWDGAILFALLVAYLTFSYFTAEKQTDDDVEDTKQNPMLSVLFIVIGISMLVGGGI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCC
LFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSVVAALKGQSDIAIGNVVGSNLFN
EEECHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHH
ILGILGVTALIHPIVGSEISTLDWISMIAFAMILLPFAYTGLRIGRREAALLVLGYLVYI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GYLVAQV
HHHHHCC
>Mature Secondary Structure
MFILLSILGGFLILTIGAEALVRGASQIALRLGLTPLIIGLTIVAFGTSAPELAVSVKSA
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHH
IAGNSGIALGNVIGSNIANIGLILGITALIRPIKIESQMVRRDIPIMIGASLLFWSLLLD
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GGLSFWDGAILFALLVAYLTFSYFTAEKQTDDDVEDTKQNPMLSVLFIVIGISMLVGGGI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCC
LFVDGAVAMAKSFGISEVIIGLTIVAIGTSMPELVTSVVAALKGQSDIAIGNVVGSNLFN
EEECHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHH
ILGILGVTALIHPIVGSEISTLDWISMIAFAMILLPFAYTGLRIGRREAALLVLGYLVYI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
GYLVAQV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]