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The map label for this gene is xpsE [H]

Identifier: 157963577

GI number: 157963577

Start: 4578008

End: 4579741

Strand: Reverse

Name: xpsE [H]

Synonym: Spea_3765

Alternate gene names: 157963577

Gene position: 4579741-4578008 (Counterclockwise)

Preceding gene: 157963578

Following gene: 157963576

Centisome position: 88.5

GC content: 48.56

Gene sequence:

>1734_bases
GTGAAACCCAAGTTAAAGATGCGACTCGGTGATCTGCTTGTTCAAGAGCAGATCATCTCTGAAGAGCAGTTACAGCAAGC
GTTAGGCGAACAGCGTAATACGGGAAAGAAGCTTGGTCGTACATTAATCGACTTGTCATGTATTACTGAGCAGCAATTAC
TACAATTTTTGTCGCATCAGCTTAACATTCCTTTTATCGATATTAGTAAGCGTGCCATCGCTACTGAAGTCGTGAGTCTG
CTACCTGAGGTGCAGGCTCGCCGTTATCGCGCTCTGGTTGTCGAAGATAATGGTGAAGGCGTGCTGGTAGCCATGAGCGA
TCCCGCCGATCTACAGGCGATGGATAATCTAGAGTTGCAGTTGGCACCTAAGAGTATCTCTATTGCTGTAGTGACAGAGC
AGCAGCTATTAGATGCGTTTGATAATCTCTATCGACGCACCGATGAGATTGCTCAAATTGCAGGTAAGCTCGAAGAGGAA
TACGCCGCCGATGATCTGTTCGATCTCGGTAGCTTGACCGATGGCGACAGTGATAACGAAACCACAGTCGTTAAACTGCT
ACAGTCTATCTTCGAAGATGCTGTGCAGATGCGCGCTTCGGATATCCATATTGAACCGGGTGAGAAAGCGCTGCGAATTC
GTCAACGTATCGACGGTCAGTTACATGAAAACATCCTACCGGAAGTTAGCATCGCAGCGGCGTTAGTATTGCGCTTAAAG
TTGATGGCGGGCTTAGATATTTCAGAGAAACGATTGCCACAAGATGGCCGTTTCCACATAGAGATTAAAGGGCATAAGAT
TGACGTTCGTATGTCGACCATGCCGATTTACCATGGTGAATCTGTGGTGATGCGTTTGCTGGACCAATCTGCTGGTCTAC
TGACCTTGAATGAAACTGGGATGCCGCCAGAAATGTTGGCGAGGATCCGTCGGCAGATCAAGCGTCCTCACGGCATGCTG
TTAGTCACGGGCCCAACGGGTAGCGGTAAAACCACTACGCTTTATGGCGTCTTGAGTGAGCTCAATACCGCAGATCGCAA
GATCATCACAGTTGAAGATCCAGTTGAATACCAGTTACCGCGTATTAATCAGGTGCAGGTAAACCATAAGATTGGTCTCG
ATTTTTCCAATGTACTGCGAACCACGTTACGACAAGATCCCGACATCATCATGGTCGGTGAGATGCGTGACCAAGAGACG
GTAGAAATTGGTCTTCGTGGCGCATTAACCGGTCACTTTGTATTATCGACCTTGCATACCAACGATGCGGTGACCAGTGC
CCTGCGTTTGCTAGACATGGGCGCGGCGAGTTATCTGGTTGCGAGCGCACTTAGAGTCATTATTGCTCAGCGCTTAGTGC
GCCGAGTGTGCCAGAACTGCGCCATCGATTATCAGCTTTCTGCCCCGGATAAAGCCTGGCTATCTAGCGTGAGCAAGCTC
GATTACTCGCAAGCGACATTTAGGATAGGTACTGGCTGTCAGAGCTGTAACGGCAGCGGTTATCGTGGTCGAATAGGTGT
ATTTGAAATTTTAGAGCTCGACGAACCAATGATTGAGGCTATGCGTACGGGCAACCCGCAGGACTTTACTCGCGCCGCTT
ATCAGAGCCCTAACTTTACGCCGCTTGCAGAATCGGCATTAAAGTACCTAGCTCAAGGGATGACAACAATCGAAGAGGTC
GCAAAACTCGTTGAAGATGTTAGTGACACTCAATTAGAATTTGGTGAGGCTTAA

Upstream 100 bases:

>100_bases
AAGCGAAATCAGCCTATAACCAAGCTTTATCCCAAGGTAACTTATCGGTACAGGCTAAAGTTTACGTCGATAATCGATTG
CTGCAGTTAGGAGCATACTA

Downstream 100 bases:

>100_bases
GCATGCCAACATATCAGTACCGCGGTCGAAGCGCTCAAGGTGAGCAGGTTAAGGGGCTAGTTGATGCAGCCTCTGAGAGT
GCGGCTGCCGATCAACTGAT

Product: type II secretion system protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MKPKLKMRLGDLLVQEQIISEEQLQQALGEQRNTGKKLGRTLIDLSCITEQQLLQFLSHQLNIPFIDISKRAIATEVVSL
LPEVQARRYRALVVEDNGEGVLVAMSDPADLQAMDNLELQLAPKSISIAVVTEQQLLDAFDNLYRRTDEIAQIAGKLEEE
YAADDLFDLGSLTDGDSDNETTVVKLLQSIFEDAVQMRASDIHIEPGEKALRIRQRIDGQLHENILPEVSIAAALVLRLK
LMAGLDISEKRLPQDGRFHIEIKGHKIDVRMSTMPIYHGESVVMRLLDQSAGLLTLNETGMPPEMLARIRRQIKRPHGML
LVTGPTGSGKTTTLYGVLSELNTADRKIITVEDPVEYQLPRINQVQVNHKIGLDFSNVLRTTLRQDPDIIMVGEMRDQET
VEIGLRGALTGHFVLSTLHTNDAVTSALRLLDMGAASYLVASALRVIIAQRLVRRVCQNCAIDYQLSAPDKAWLSSVSKL
DYSQATFRIGTGCQSCNGSGYRGRIGVFEILELDEPMIEAMRTGNPQDFTRAAYQSPNFTPLAESALKYLAQGMTTIEEV
AKLVEDVSDTQLEFGEA

Sequences:

>Translated_577_residues
MKPKLKMRLGDLLVQEQIISEEQLQQALGEQRNTGKKLGRTLIDLSCITEQQLLQFLSHQLNIPFIDISKRAIATEVVSL
LPEVQARRYRALVVEDNGEGVLVAMSDPADLQAMDNLELQLAPKSISIAVVTEQQLLDAFDNLYRRTDEIAQIAGKLEEE
YAADDLFDLGSLTDGDSDNETTVVKLLQSIFEDAVQMRASDIHIEPGEKALRIRQRIDGQLHENILPEVSIAAALVLRLK
LMAGLDISEKRLPQDGRFHIEIKGHKIDVRMSTMPIYHGESVVMRLLDQSAGLLTLNETGMPPEMLARIRRQIKRPHGML
LVTGPTGSGKTTTLYGVLSELNTADRKIITVEDPVEYQLPRINQVQVNHKIGLDFSNVLRTTLRQDPDIIMVGEMRDQET
VEIGLRGALTGHFVLSTLHTNDAVTSALRLLDMGAASYLVASALRVIIAQRLVRRVCQNCAIDYQLSAPDKAWLSSVSKL
DYSQATFRIGTGCQSCNGSGYRGRIGVFEILELDEPMIEAMRTGNPQDFTRAAYQSPNFTPLAESALKYLAQGMTTIEEV
AKLVEDVSDTQLEFGEA
>Mature_577_residues
MKPKLKMRLGDLLVQEQIISEEQLQQALGEQRNTGKKLGRTLIDLSCITEQQLLQFLSHQLNIPFIDISKRAIATEVVSL
LPEVQARRYRALVVEDNGEGVLVAMSDPADLQAMDNLELQLAPKSISIAVVTEQQLLDAFDNLYRRTDEIAQIAGKLEEE
YAADDLFDLGSLTDGDSDNETTVVKLLQSIFEDAVQMRASDIHIEPGEKALRIRQRIDGQLHENILPEVSIAAALVLRLK
LMAGLDISEKRLPQDGRFHIEIKGHKIDVRMSTMPIYHGESVVMRLLDQSAGLLTLNETGMPPEMLARIRRQIKRPHGML
LVTGPTGSGKTTTLYGVLSELNTADRKIITVEDPVEYQLPRINQVQVNHKIGLDFSNVLRTTLRQDPDIIMVGEMRDQET
VEIGLRGALTGHFVLSTLHTNDAVTSALRLLDMGAASYLVASALRVIIAQRLVRRVCQNCAIDYQLSAPDKAWLSSVSKL
DYSQATFRIGTGCQSCNGSGYRGRIGVFEILELDEPMIEAMRTGNPQDFTRAAYQSPNFTPLAESALKYLAQGMTTIEEV
AKLVEDVSDTQLEFGEA

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=429, Percent_Identity=43.3566433566434, Blast_Score=324, Evalue=1e-89,
Organism=Escherichia coli, GI1786296, Length=483, Percent_Identity=40.3726708074534, Blast_Score=318, Evalue=6e-88,
Organism=Escherichia coli, GI87082188, Length=197, Percent_Identity=40.1015228426396, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007831
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF05157 GSPII_E_N [H]

EC number: NA

Molecular weight: Translated: 64085; Mature: 64085

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKLKMRLGDLLVQEQIISEEQLQQALGEQRNTGKKLGRTLIDLSCITEQQLLQFLSHQ
CCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHH
LNIPFIDISKRAIATEVVSLLPEVQARRYRALVVEDNGEGVLVAMSDPADLQAMDNLELQ
CCCCEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEEECCCCCCHHHCCCEEE
LAPKSISIAVVTEQQLLDAFDNLYRRTDEIAQIAGKLEEEYAADDLFDLGSLTDGDSDNE
EECCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
TTVVKLLQSIFEDAVQMRASDIHIEPGEKALRIRQRIDGQLHENILPEVSIAAALVLRLK
HHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHH
LMAGLDISEKRLPQDGRFHIEIKGHKIDVRMSTMPIYHGESVVMRLLDQSAGLLTLNETG
HHHCCCCHHHHCCCCCCEEEEEECCEEEEEEEEECEECCHHHHHHHHHCCCCEEEECCCC
MPPEMLARIRRQIKRPHGMLLVTGPTGSGKTTTLYGVLSELNTADRKIITVEDPVEYQLP
CCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCC
RINQVQVNHKIGLDFSNVLRTTLRQDPDIIMVGEMRDQETVEIGLRGALTGHFVLSTLHT
CCCEEEECCEECCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
NDAVTSALRLLDMGAASYLVASALRVIIAQRLVRRVCQNCAIDYQLSAPDKAWLSSVSKL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHC
DYSQATFRIGTGCQSCNGSGYRGRIGVFEILELDEPMIEAMRTGNPQDFTRAAYQSPNFT
CCCHHEEEECCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCC
PLAESALKYLAQGMTTIEEVAKLVEDVSDTQLEFGEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKPKLKMRLGDLLVQEQIISEEQLQQALGEQRNTGKKLGRTLIDLSCITEQQLLQFLSHQ
CCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHH
LNIPFIDISKRAIATEVVSLLPEVQARRYRALVVEDNGEGVLVAMSDPADLQAMDNLELQ
CCCCEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEEECCCCCCHHHCCCEEE
LAPKSISIAVVTEQQLLDAFDNLYRRTDEIAQIAGKLEEEYAADDLFDLGSLTDGDSDNE
EECCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
TTVVKLLQSIFEDAVQMRASDIHIEPGEKALRIRQRIDGQLHENILPEVSIAAALVLRLK
HHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHH
LMAGLDISEKRLPQDGRFHIEIKGHKIDVRMSTMPIYHGESVVMRLLDQSAGLLTLNETG
HHHCCCCHHHHCCCCCCEEEEEECCEEEEEEEEECEECCHHHHHHHHHCCCCEEEECCCC
MPPEMLARIRRQIKRPHGMLLVTGPTGSGKTTTLYGVLSELNTADRKIITVEDPVEYQLP
CCHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCC
RINQVQVNHKIGLDFSNVLRTTLRQDPDIIMVGEMRDQETVEIGLRGALTGHFVLSTLHT
CCCEEEECCEECCCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
NDAVTSALRLLDMGAASYLVASALRVIIAQRLVRRVCQNCAIDYQLSAPDKAWLSSVSKL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHC
DYSQATFRIGTGCQSCNGSGYRGRIGVFEILELDEPMIEAMRTGNPQDFTRAAYQSPNFT
CCCHHEEEECCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCC
PLAESALKYLAQGMTTIEEVAKLVEDVSDTQLEFGEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1944223; 12024217 [H]