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The map label for this gene is pilC [H]

Identifier: 157963576

GI number: 157963576

Start: 4576785

End: 4578005

Strand: Reverse

Name: pilC [H]

Synonym: Spea_3764

Alternate gene names: 157963576

Gene position: 4578005-4576785 (Counterclockwise)

Preceding gene: 157963577

Following gene: 157963575

Centisome position: 88.47

GC content: 47.58

Gene sequence:

>1221_bases
ATGCCAACATATCAGTACCGCGGTCGAAGCGCTCAAGGTGAGCAGGTTAAGGGGCTAGTTGATGCAGCCTCTGAGAGTGC
GGCTGCCGATCAACTGATGTCTCGCGGGGTGATCCCGCTCGAGCTCGTGTTAGCAAAAGAGGTTAAGGAGTTTAATCTTA
AGACTTTATTTAAAGGTAAAGTCGCGTTAGAAGAGTTACAGATCTTCACTCGGCAGATGTACTCACTGACACGTTCAGGC
ATTCCCATCTTACGAGCGATTGCAGGTCTTTCTGAGACGACACATTCTGTTCGCATGAAAGAGGCGCTCGATGATATTTC
TGAACAGTTGACCTCTGGCCGTCCTCTATCTTCGGCGATGAATCAGCATCCTGATGTATTTGATGCGCTGTTTGTCTCTA
TGGTTCATGTAGGTGAAAACACCGGTAAGCTTGAGGATGCATTTATTCAGTTATCTGGTTATATCGAGCGTGAGCAGGAG
ACTCGAAGACGCATCAAAGCGGCGATGCGTTATCCGATCTTTGTATTAATCGCGATCGCCATAGCCATGGTGATCCTCAA
CATTATGGTGATCCCTAAATTTGCCGAGATGTTTTCCCGATTTGGCGCGGATCTTCCTTGGGCGACTAAACTATTAATTA
ATACCTCTAATGTGTTTGTTAACTACTGGCCTTTAATGCTCCTCGTGCTGGTGGCGGGATTCGTTGGCATTCGCTATTGG
CATAGCACCGAAAAAGGTGAGAAGCAGTGGGATAAATGGAAGTTAAATATTCCCGCTGTTGGTAGCATCATCGAACGTTC
AACCCTCTCGCGCTATTGCCGCAGTTTCTCAATGATGTTGAGTGCGGGTGTACCCATGACCCAAGCCCTTAGTCTTGTGG
CGGACGCCGTCGATAATGCTTATATGCACGACAGCATAGTGGGGATGCGTCGTGGTATCGAGTCCGGTGAGTCGATGTTA
AGAGTATCGAATAACAGCCAATTATTTACGCCACTTGTGCTGCAGATGGTGGCAGTGGGTGAAGAAACGGGCCAGATCGA
TCAGTTGCTTAATGATGCTGCAGATTTTTATGAAGGTGAAGTCGATTACGACCTGAAGAATTTGACTGCCAAGCTAGAGC
CTCTTTTGATCGGTTTTGTCGCCTGTATCGTGTTGGTGTTGGCGCTGGGTATTTACCTACCTATGTGGGACATGTTGAAT
GTGGTTAAGGGCGGTAACTGA

Upstream 100 bases:

>100_bases
CATTAAAGTACCTAGCTCAAGGGATGACAACAATCGAAGAGGTCGCAAAACTCGTTGAAGATGTTAGTGACACTCAATTA
GAATTTGGTGAGGCTTAAGC

Downstream 100 bases:

>100_bases
TGAAGCAGGAAAAGCCCCGTGCTTAGTCAACATAAAGCCGATTCAGAGCTGTTGAATGTCTATGGCAAACTTATAGCCTT
AATTATTCTACTAATTGTAT

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MPTYQYRGRSAQGEQVKGLVDAASESAAADQLMSRGVIPLELVLAKEVKEFNLKTLFKGKVALEELQIFTRQMYSLTRSG
IPILRAIAGLSETTHSVRMKEALDDISEQLTSGRPLSSAMNQHPDVFDALFVSMVHVGENTGKLEDAFIQLSGYIEREQE
TRRRIKAAMRYPIFVLIAIAIAMVILNIMVIPKFAEMFSRFGADLPWATKLLINTSNVFVNYWPLMLLVLVAGFVGIRYW
HSTEKGEKQWDKWKLNIPAVGSIIERSTLSRYCRSFSMMLSAGVPMTQALSLVADAVDNAYMHDSIVGMRRGIESGESML
RVSNNSQLFTPLVLQMVAVGEETGQIDQLLNDAADFYEGEVDYDLKNLTAKLEPLLIGFVACIVLVLALGIYLPMWDMLN
VVKGGN

Sequences:

>Translated_406_residues
MPTYQYRGRSAQGEQVKGLVDAASESAAADQLMSRGVIPLELVLAKEVKEFNLKTLFKGKVALEELQIFTRQMYSLTRSG
IPILRAIAGLSETTHSVRMKEALDDISEQLTSGRPLSSAMNQHPDVFDALFVSMVHVGENTGKLEDAFIQLSGYIEREQE
TRRRIKAAMRYPIFVLIAIAIAMVILNIMVIPKFAEMFSRFGADLPWATKLLINTSNVFVNYWPLMLLVLVAGFVGIRYW
HSTEKGEKQWDKWKLNIPAVGSIIERSTLSRYCRSFSMMLSAGVPMTQALSLVADAVDNAYMHDSIVGMRRGIESGESML
RVSNNSQLFTPLVLQMVAVGEETGQIDQLLNDAADFYEGEVDYDLKNLTAKLEPLLIGFVACIVLVLALGIYLPMWDMLN
VVKGGN
>Mature_405_residues
PTYQYRGRSAQGEQVKGLVDAASESAAADQLMSRGVIPLELVLAKEVKEFNLKTLFKGKVALEELQIFTRQMYSLTRSGI
PILRAIAGLSETTHSVRMKEALDDISEQLTSGRPLSSAMNQHPDVFDALFVSMVHVGENTGKLEDAFIQLSGYIEREQET
RRRIKAAMRYPIFVLIAIAIAMVILNIMVIPKFAEMFSRFGADLPWATKLLINTSNVFVNYWPLMLLVLVAGFVGIRYWH
STEKGEKQWDKWKLNIPAVGSIIERSTLSRYCRSFSMMLSAGVPMTQALSLVADAVDNAYMHDSIVGMRRGIESGESMLR
VSNNSQLFTPLVLQMVAVGEETGQIDQLLNDAADFYEGEVDYDLKNLTAKLEPLLIGFVACIVLVLALGIYLPMWDMLNV
VKGGN

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=396, Percent_Identity=26.2626262626263, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1786295, Length=407, Percent_Identity=25.3071253071253, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45231; Mature: 45100

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PTYQYRGRSAQGEQVKGLVDAASESAAADQLMSRGVIPLELVLAKEVKEFNLKTLFKGK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHH
VALEELQIFTRQMYSLTRSGIPILRAIAGLSETTHSVRMKEALDDISEQLTSGRPLSSAM
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NQHPDVFDALFVSMVHVGENTGKLEDAFIQLSGYIEREQETRRRIKAAMRYPIFVLIAIA
HCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAMVILNIMVIPKFAEMFSRFGADLPWATKLLINTSNVFVNYWPLMLLVLVAGFVGIRYW
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHH
HSTEKGEKQWDKWKLNIPAVGSIIERSTLSRYCRSFSMMLSAGVPMTQALSLVADAVDNA
CCCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YMHDSIVGMRRGIESGESMLRVSNNSQLFTPLVLQMVAVGEETGQIDQLLNDAADFYEGE
HHHHHHHHHHHCHHCCCHHEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VDYDLKNLTAKLEPLLIGFVACIVLVLALGIYLPMWDMLNVVKGGN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]