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The map label for this gene is mreB [H]

Identifier: 157963566

GI number: 157963566

Start: 4566261

End: 4567310

Strand: Reverse

Name: mreB [H]

Synonym: Spea_3754

Alternate gene names: 157963566

Gene position: 4567310-4566261 (Counterclockwise)

Preceding gene: 157963567

Following gene: 157963565

Centisome position: 88.26

GC content: 48.29

Gene sequence:

>1050_bases
ATGTTCAAGAAGCTACGCGGCATTTTTTCTAATGATCTTTCGATCGATTTGGGTACAGCAAATACACTAATTTATGTCCG
TGAAGAAGGCATAGTGCTAAACGAACCGTCAGTAGTCGCGATTCGTGGAGAGCGAAGCGGTTCAGGTCAGAAGTCGGTTG
CGGCCGTCGGTACTGAAGCAAAGCAGATGCTAGGTCGTACTCCTGGAAACATTCAAGCAATTCGTCCGATGAAAGATGGC
GTTATCGCCGACTTTTATGTCACCGAAAAAATGCTTCAGCATTTTATCAAGCAAGTGCATAACAACAGTGTGTTCCGTCC
AAGCCCCCGTGTTCTTGTGTGTGTGCCTGTTGGCGCAACGCAAGTTGAACGCCGTGCAATCCGAGAGTCTGCTATGGGCG
CGGGTGCGCGTGAAGTGTATTTGATTGAAGAGCCAATGGCTGCTGCAATCGGTGCAGGTCTACCGGTTTCTGAAGCAACG
GGTTCTATGGTTGTCGATATTGGTGGTGGTACCACAGAAGTCGCAATCATCTCGCTAAACGGTGTGGTTTACTCATCGTC
TGTACGCATCGGTGGTGACAAGTTTGATGATGCGATCATCAACTATGTGCGTCGTAACTACGGTAGCTTAATTGGTGAAG
CGACGGCTGAGCGTATCAAGCACACAATCGGTACTGCATACCCAGGCGATGAAGTGTTAGAAATTGAAGTTCGCGGTCGT
AACCTTGCAGAAGGTGTACCACGTAGCTTTACATTGAACAGCAATGAAATTTTAGAAGCACTGCAAGAGCCGTTATCAGG
CATTGTGAGTGCGGTAATGGTTGCCCTTGAGCAGTCTCCTCCAGAATTGGCATCAGATATCTCTGAGCGTGGCATGGTAC
TAACTGGCGGTGGCGCGTTAATTCGTGACCTAGACAGATTACTTATGCAAGAAACTGGTATTCCTGTGATGATCGCAGAA
GACCCACTAACTTGTGTGGCTCGCGGTGGTGGTAGAGCTTTAGAGATGATCGATATGCATGGCGGCGACCTGTTCTCTGA
AGAAAACTAA

Upstream 100 bases:

>100_bases
ATTAGCAATAGTTAACCTCTCTGGTCTTGTGGATTTTAAGAAGCGTGATAAAGTTACCTGATTTCTTTTTTCTACGACTC
CACAGAGACAGGCTGGTTAC

Downstream 100 bases:

>100_bases
CCACGGTTAAAAAGGGCGGTAATACACCGCCCTAGTTTGTTATGAAGCCTATTTTTGCTCGCGGTATTTCCAACCAATTT
CGATTAACACTGGCTGTTAT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRGERSGSGQKSVAAVGTEAKQMLGRTPGNIQAIRPMKDG
VIADFYVTEKMLQHFIKQVHNNSVFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALIRDLDRLLMQETGIPVMIAE
DPLTCVARGGGRALEMIDMHGGDLFSEEN

Sequences:

>Translated_349_residues
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRGERSGSGQKSVAAVGTEAKQMLGRTPGNIQAIRPMKDG
VIADFYVTEKMLQHFIKQVHNNSVFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALIRDLDRLLMQETGIPVMIAE
DPLTCVARGGGRALEMIDMHGGDLFSEEN
>Mature_349_residues
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRGERSGSGQKSVAAVGTEAKQMLGRTPGNIQAIRPMKDG
VIADFYVTEKMLQHFIKQVHNNSVFRPSPRVLVCVPVGATQVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEAT
GSMVVDIGGGTTEVAIISLNGVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGALIRDLDRLLMQETGIPVMIAE
DPLTCVARGGGRALEMIDMHGGDLFSEEN

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=352, Percent_Identity=25.8522727272727, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082236, Length=348, Percent_Identity=89.9425287356322, Blast_Score=629, Evalue=0.0,
Organism=Escherichia coli, GI1786870, Length=356, Percent_Identity=24.7191011235955, Blast_Score=61, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319972, Length=360, Percent_Identity=23.0555555555556, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324120, Length=360, Percent_Identity=22.7777777777778, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37251; Mature: 37251

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRGERSGSGQKSVAAVGTEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCCCCHHHHHCHHH
KQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSVFRPSPRVLVCVPVGAT
HHHHCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHH
QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
CEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL
CHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCHH
IRDLDRLLMQETGIPVMIAEDPLTCVARGGGRALEMIDMHGGDLFSEEN
HHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MFKKLRGIFSNDLSIDLGTANTLIYVREEGIVLNEPSVVAIRGERSGSGQKSVAAVGTEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCCCCHHHHHCHHH
KQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSVFRPSPRVLVCVPVGAT
HHHHCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHH
QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR
CEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL
CHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCHH
IRDLDRLLMQETGIPVMIAEDPLTCVARGGGRALEMIDMHGGDLFSEEN
HHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]