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The map label for this gene is tldD [H]

Identifier: 157963559

GI number: 157963559

Start: 4555864

End: 4557345

Strand: Reverse

Name: tldD [H]

Synonym: Spea_3747

Alternate gene names: 157963559

Gene position: 4557345-4555864 (Counterclockwise)

Preceding gene: 157963560

Following gene: 157963558

Centisome position: 88.07

GC content: 50.54

Gene sequence:

>1482_bases
ATGTTTTATCGAATCAATATGAAGAGAGAAGAGATGCCATTTTTAACTCAAGTTGGACAGAGCTTATTGCAAGATGGGCT
AGCATTAGATGATCTACAAAGCTATTTAAAGCAGATCCACCAGCATCAAATTGACTTCTCAGACCTTTACTTTCAAGGCA
GCCGTCATGAATCTTGGGTACTGGAAGATGGCATCGTTAAAGACGGTAGCTTTCATATTGAACGTGGCGTGGGTGTTCGA
GCTATTACCGGCGAAAAAACCGGTTTTGCTTACGCCGATGAGATTACGCCAGCGGCACTAGAGGCTGCGGCAACAGCGGC
GCGTGGTATTGCTATCGCCGGCGGTGAAGGTAAGGTCAATGCCTGGAAGCAGCAGCAGAGCAAGGCGCTCTATATCAGCT
CAGATCCTATCGCCGCGATGGAAGAGGTGAAAAAGATTGAGCTGCTAAAGCAGGCCGATGTGTATATTCGCAGCCTAGAC
AGCCGCATTATTCAGGTTGTAGTGAGCCTGTCTGGCGTGCATGAAGAGATTTTAGTCGCGGCGAGTGACGGGACTTTAGC
GGCAGATATTCGTCCGTTAGTGCGCTTTAACTGTAGCGTGATTTTAGAAGACGACGGCAAGCGTGAACGCGGCGCTTCTG
GTGGCGGCGGACGTCACGACTACAGTGTGTTGCTAGAAGATGGCGACGATGGTTTGCCATATTGCTTTGGTTTTGCCCGT
GAGGCTGTGCGCCAAGCGCAAGTAAACTTACTAGCCATCGACGCTCCAGCAGGCGAAATGCCTGTGGTACTCGGTGCAGG
CTGGCCAGGTGTACTACTGCACGAAGCCGTGGGTCACGGCCTAGAAGGCGACTTTAACCGTAAGGGCAGCAGTGCCTTTA
GTGGCAAGGTCGGTCAGCAGGTGGCGTCAGAGTTAGTGACAGTGGTTGACGATGGCACCATAGCTAATCGACGTGGATCA
TTATCTATCGATGATGAAGGCGTACCTACTCAGAAGACGGTACTGATCGAAAACGGGATCTTGAAAGGCTATATGCAAGA
CAAGCTCAACGCGCGCTTGATGGGTGAGCAGTCTACCGGTAACGGCCGTCGCGAATCTTATGCTCATCTTCCTATGCCAC
GCATGACCAATACTTATATGGAAGCGGGCGAGTCTGATCCTGCTGAGATCATCAAATCGGTTAAGAAAGGGGTATACGCA
CCTAACTTTGGCGGCGGTCAGGTGGATATTACTTCGGGTAAGTTTGTGTTCTCTGCATCAGAAGCTTACTTGATTGAAAA
CGGTGAGATCACTCAGCCGATCAAAGGCGCAACTCTGATTGGCAATGGTCCAGAGTCGATGAGCCAGATCTCTATGGTTG
GTAACGATCTAGCGCTGGATAAGGGCGTGGGTGTTTGTGGTAAAGATGGCCAAAGCGTGCCTGTCGGTGTGGGCCAACCT
ACATTAAAACTGGACAAATTGACCGTTGGCGGTACTGCTTAG

Upstream 100 bases:

>100_bases
CCAGTACTTAAGTCGCACAGCTAAGACCAAATACTAAGAGCAAGTCGAACCATAAATTTAAGGTAAATTGAGGCTCACGC
GTGAGACTCTGTTTACCGAA

Downstream 100 bases:

>100_bases
TCAAACTGCAGCACAAGCTAGGATTTAGCGAGCAAATAATCGACTAAATCCTAGCGAGCAAAACTTAGCAATGCTAGAAT
CCAGTAATTAATTAGAGTAA

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MFYRINMKREEMPFLTQVGQSLLQDGLALDDLQSYLKQIHQHQIDFSDLYFQGSRHESWVLEDGIVKDGSFHIERGVGVR
AITGEKTGFAYADEITPAALEAAATAARGIAIAGGEGKVNAWKQQQSKALYISSDPIAAMEEVKKIELLKQADVYIRSLD
SRIIQVVVSLSGVHEEILVAASDGTLAADIRPLVRFNCSVILEDDGKRERGASGGGGRHDYSVLLEDGDDGLPYCFGFAR
EAVRQAQVNLLAIDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQQVASELVTVVDDGTIANRRGS
LSIDDEGVPTQKTVLIENGILKGYMQDKLNARLMGEQSTGNGRRESYAHLPMPRMTNTYMEAGESDPAEIIKSVKKGVYA
PNFGGGQVDITSGKFVFSASEAYLIENGEITQPIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQP
TLKLDKLTVGGTA

Sequences:

>Translated_493_residues
MFYRINMKREEMPFLTQVGQSLLQDGLALDDLQSYLKQIHQHQIDFSDLYFQGSRHESWVLEDGIVKDGSFHIERGVGVR
AITGEKTGFAYADEITPAALEAAATAARGIAIAGGEGKVNAWKQQQSKALYISSDPIAAMEEVKKIELLKQADVYIRSLD
SRIIQVVVSLSGVHEEILVAASDGTLAADIRPLVRFNCSVILEDDGKRERGASGGGGRHDYSVLLEDGDDGLPYCFGFAR
EAVRQAQVNLLAIDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQQVASELVTVVDDGTIANRRGS
LSIDDEGVPTQKTVLIENGILKGYMQDKLNARLMGEQSTGNGRRESYAHLPMPRMTNTYMEAGESDPAEIIKSVKKGVYA
PNFGGGQVDITSGKFVFSASEAYLIENGEITQPIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQP
TLKLDKLTVGGTA
>Mature_493_residues
MFYRINMKREEMPFLTQVGQSLLQDGLALDDLQSYLKQIHQHQIDFSDLYFQGSRHESWVLEDGIVKDGSFHIERGVGVR
AITGEKTGFAYADEITPAALEAAATAARGIAIAGGEGKVNAWKQQQSKALYISSDPIAAMEEVKKIELLKQADVYIRSLD
SRIIQVVVSLSGVHEEILVAASDGTLAADIRPLVRFNCSVILEDDGKRERGASGGGGRHDYSVLLEDGDDGLPYCFGFAR
EAVRQAQVNLLAIDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQQVASELVTVVDDGTIANRRGS
LSIDDEGVPTQKTVLIENGILKGYMQDKLNARLMGEQSTGNGRRESYAHLPMPRMTNTYMEAGESDPAEIIKSVKKGVYA
PNFGGGQVDITSGKFVFSASEAYLIENGEITQPIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQP
TLKLDKLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=474, Percent_Identity=67.9324894514768, Blast_Score=620, Evalue=1e-179,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 52628; Mature: 52628

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYRINMKREEMPFLTQVGQSLLQDGLALDDLQSYLKQIHQHQIDFSDLYFQGSRHESWV
CEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHEEECCCCCCEE
LEDGIVKDGSFHIERGVGVRAITGEKTGFAYADEITPAALEAAATAARGIAIAGGEGKVN
ECCCCCCCCCEEEECCCCEEEEECCCCCCEECCCCCHHHHHHHHHHHCCEEEECCCCCCC
AWKQQQSKALYISSDPIAAMEEVKKIELLKQADVYIRSLDSRIIQVVVSLSGVHEEILVA
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
ASDGTLAADIRPLVRFNCSVILEDDGKRERGASGGGGRHDYSVLLEDGDDGLPYCFGFAR
ECCCCEEHHCHHHHEECCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
EAVRQAQVNLLAIDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQQ
HHHHHHCEEEEEEECCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
VASELVTVVDDGTIANRRGSLSIDDEGVPTQKTVLIENGILKGYMQDKLNARLMGEQSTG
HHHHHHHHHCCCCEECCCCCEEECCCCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCCC
NGRRESYAHLPMPRMTNTYMEAGESDPAEIIKSVKKGVYAPNFGGGQVDITSGKFVFSAS
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECC
EAYLIENGEITQPIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQP
CEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHCCCEEHHCCCCCCCCCCCCCCCCCCCC
TLKLDKLTVGGTA
CEEEEEEECCCCC
>Mature Secondary Structure
MFYRINMKREEMPFLTQVGQSLLQDGLALDDLQSYLKQIHQHQIDFSDLYFQGSRHESWV
CEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHEEECCCCCCEE
LEDGIVKDGSFHIERGVGVRAITGEKTGFAYADEITPAALEAAATAARGIAIAGGEGKVN
ECCCCCCCCCEEEECCCCEEEEECCCCCCEECCCCCHHHHHHHHHHHCCEEEECCCCCCC
AWKQQQSKALYISSDPIAAMEEVKKIELLKQADVYIRSLDSRIIQVVVSLSGVHEEILVA
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
ASDGTLAADIRPLVRFNCSVILEDDGKRERGASGGGGRHDYSVLLEDGDDGLPYCFGFAR
ECCCCEEHHCHHHHEECCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
EAVRQAQVNLLAIDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQQ
HHHHHHCEEEEEEECCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
VASELVTVVDDGTIANRRGSLSIDDEGVPTQKTVLIENGILKGYMQDKLNARLMGEQSTG
HHHHHHHHHCCCCEECCCCCEEECCCCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCCC
NGRRESYAHLPMPRMTNTYMEAGESDPAEIIKSVKKGVYAPNFGGGQVDITSGKFVFSAS
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECC
EAYLIENGEITQPIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQP
CEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHCCCEEHHCCCCCCCCCCCCCCCCCCCC
TLKLDKLTVGGTA
CEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]