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The map label for this gene is hflX [H]

Identifier: 157963353

GI number: 157963353

Start: 4322322

End: 4323617

Strand: Reverse

Name: hflX [H]

Synonym: Spea_3539

Alternate gene names: 157963353

Gene position: 4323617-4322322 (Counterclockwise)

Preceding gene: 157963354

Following gene: 157963352

Centisome position: 83.55

GC content: 44.91

Gene sequence:

>1296_bases
TTGTTTGATCGTTATGAGGCGGGAGAGAAAGCGGTACTTGTCCATATCGACTTTACTGATGAAAACAACCGAGAAGACTT
AGATGAGCTAAAGCTTTTAGTTGACTCGGCTGGTGCTCAGTCAATTGGTGTGATCTCAGGAAGTCGTCGTTCACCGGACC
GTAAATATTTTGTTGGCTCGGGCAAGGCTGAAGAATTAGCTGCGATGGTTGCGGCAACGGATGCCAATGTGGTTATATTT
AATCACAAATTAAGTCCGGCTCAAGAGCGTAATCTTGAGAAAATTTGCGAGTGCCGTGTACTAGACAGAACAACTTTGAT
CTTGGATATTTTTGCTCAAAGAGCAAGAACATTCGAAGGTAAGCTACAGGTGGAGCTAGCGCAATTGCGCCACATGTCTA
CTCGCCTGATCAGAGGTTGGACGCATTTAGAGCGTCAAAAAGGCGGTATTGGTCTTCGTGGCCCTGGTGAAACTCAATTA
GAAACCGATAGGCGTCTATTGAGAGGAAGGATCCGCACAATTAATCGTCGCTTAGAGAAAGTTGATAAGCAGCGTGATCA
GAGCCGTAGAGCACGTCAACGCAGTGATATGTCAACCGTGTCTTTGGTAGGTTATACCAACGCGGGTAAATCGACACTGT
TTAACGGCTTAACAACATCTGATGTTTATGCTGCGGATCAGCTTTTTGCGACATTAGATCCAACGTTACGTAAGTTAGAA
TTGCCTGATGGTGATGTTATCCTTGCTGATACTGTTGGATTTATTAGGCATCTGCCTCATGATTTAGTCGCTGCATTTAA
AGCAACGCTGCAAGAAACACGACAGGCAGATCTACTGCTGCATGTTGTCGATAGTGCAGATGAAAAGATGGCCGATAACT
TTGAGCAAGTTCAAAAAGTGCTCAAAGAGATCGATGCCATAGATATTCCACAGTTGATCGTTTGCAATAAAATCGATCTA
TTGGATGAGGTGAAACCACGCATCGACTACGATGACGAGGGGACACCGATTAGAGTCTGGGTTTCTGCTCAGCAGCAAAA
AGGCTTGGAATTAGTTGAGGACGCCATTAACCAACTTGTTGGTAAAGCAATCCAAGAGCTAACCTTGCAAATCCCAGCTT
CGGCGGGGCATTATCTCGGCCAGTTTTATAAACTGGATGTAATACAGCAGAAAGAGTATGACGATCTGGGGAACTGTATG
ATCTCTGTTCGCTTATTGGATGCCGATTGGCGCCGATTAGTAAAACAGAGCCAAGGTGAATTAGAGACTTTTGTGGTCGA
CCCAGTCGTCGCATAA

Upstream 100 bases:

>100_bases
CATTCAACGTGAGCAACCACCAAGCGACAAATGCTCAAGCTGGCTATAACGCTCAGCATGACGATGGCGACGAGAAGTAA
CTTGTTAAGGAGATTGCTTT

Downstream 100 bases:

>100_bases
TTAAGTATTTTAGTAATCTCGTTTATTTCATACACTTATGGAGTACTAAATGGCTTGGAACGAGCCCGGTAACAAGGGTC
AAGACCCTTGGGGAAATGGC

Product: small GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MFDRYEAGEKAVLVHIDFTDENNREDLDELKLLVDSAGAQSIGVISGSRRSPDRKYFVGSGKAEELAAMVAATDANVVIF
NHKLSPAQERNLEKICECRVLDRTTLILDIFAQRARTFEGKLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIRTINRRLEKVDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLE
LPDGDVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMADNFEQVQKVLKEIDAIDIPQLIVCNKIDL
LDEVKPRIDYDDEGTPIRVWVSAQQQKGLELVEDAINQLVGKAIQELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGNCM
ISVRLLDADWRRLVKQSQGELETFVVDPVVA

Sequences:

>Translated_431_residues
MFDRYEAGEKAVLVHIDFTDENNREDLDELKLLVDSAGAQSIGVISGSRRSPDRKYFVGSGKAEELAAMVAATDANVVIF
NHKLSPAQERNLEKICECRVLDRTTLILDIFAQRARTFEGKLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIRTINRRLEKVDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLE
LPDGDVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMADNFEQVQKVLKEIDAIDIPQLIVCNKIDL
LDEVKPRIDYDDEGTPIRVWVSAQQQKGLELVEDAINQLVGKAIQELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGNCM
ISVRLLDADWRRLVKQSQGELETFVVDPVVA
>Mature_431_residues
MFDRYEAGEKAVLVHIDFTDENNREDLDELKLLVDSAGAQSIGVISGSRRSPDRKYFVGSGKAEELAAMVAATDANVVIF
NHKLSPAQERNLEKICECRVLDRTTLILDIFAQRARTFEGKLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIRTINRRLEKVDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLE
LPDGDVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMADNFEQVQKVLKEIDAIDIPQLIVCNKIDL
LDEVKPRIDYDDEGTPIRVWVSAQQQKGLELVEDAINQLVGKAIQELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGNCM
ISVRLLDADWRRLVKQSQGELETFVVDPVVA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=267, Percent_Identity=34.8314606741573, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI310133118, Length=269, Percent_Identity=34.5724907063197, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI310124269, Length=249, Percent_Identity=35.3413654618474, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310124267, Length=249, Percent_Identity=35.3413654618474, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310124171, Length=249, Percent_Identity=35.3413654618474, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310124169, Length=249, Percent_Identity=35.3413654618474, Blast_Score=116, Evalue=3e-26,
Organism=Escherichia coli, GI1790615, Length=417, Percent_Identity=63.3093525179856, Blast_Score=541, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI17561038, Length=274, Percent_Identity=32.4817518248175, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24650079, Length=390, Percent_Identity=31.025641025641, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48601; Mature: 48601

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYEAGEKAVLVHIDFTDENNREDLDELKLLVDSAGAQSIGVISGSRRSPDRKYFVGS
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECC
GKAEELAAMVAATDANVVIFNHKLSPAQERNLEKICECRVLDRTTLILDIFAQRARTFEG
CCHHHHHHHHHCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRIRTINRRLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLE
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHCHHHHEEE
LPDGDVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMADNFEQVQKV
CCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LKEIDAIDIPQLIVCNKIDLLDEVKPRIDYDDEGTPIRVWVSAQQQKGLELVEDAINQLV
HHHCCCCCCCHHHHCCCHHHHHHCCCCCCCCCCCCCEEEEEECCHHCCHHHHHHHHHHHH
GKAIQELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGNCMISVRLLDADWRRLVKQSQGE
HHHHHHHHEECCCCCCHHHHHHHEEEHHCCCCCCCCCCEEEEEEEECHHHHHHHHHCCCC
LETFVVDPVVA
EEEEEECCCCC
>Mature Secondary Structure
MFDRYEAGEKAVLVHIDFTDENNREDLDELKLLVDSAGAQSIGVISGSRRSPDRKYFVGS
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECC
GKAEELAAMVAATDANVVIFNHKLSPAQERNLEKICECRVLDRTTLILDIFAQRARTFEG
CCHHHHHHHHHCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRIRTINRRLEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLE
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHCHHHHEEE
LPDGDVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMADNFEQVQKV
CCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LKEIDAIDIPQLIVCNKIDLLDEVKPRIDYDDEGTPIRVWVSAQQQKGLELVEDAINQLV
HHHCCCCCCCHHHHCCCHHHHHHCCCCCCCCCCCCCEEEEEECCHHCCHHHHHHHHHHHH
GKAIQELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGNCMISVRLLDADWRRLVKQSQGE
HHHHHHHHEECCCCCCHHHHHHHEEEHHCCCCCCCCCCEEEEEEEECHHHHHHHHHCCCC
LETFVVDPVVA
EEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]