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The map label for this gene is visC [H]

Identifier: 157963120

GI number: 157963120

Start: 4047593

End: 4048813

Strand: Reverse

Name: visC [H]

Synonym: Spea_3304

Alternate gene names: 157963120

Gene position: 4048813-4047593 (Counterclockwise)

Preceding gene: 157963121

Following gene: 157963119

Centisome position: 78.24

GC content: 50.2

Gene sequence:

>1221_bases
ATGTTAAGCACACAAACTTATGATGTCGCAATTGTTGGTGGAGGCATGGTTGGCCTTGCAACGGCTATTGGTTTAGCGAT
GGAAGGCATTAAAGTCGTGGTGATTGATGCGGGTCAGACCCAAGCGGTATCGGGTGCCCCTAAGCTTAGGGTTAGCGCCA
TCAACAAGGCCAGCCAACAGCTGATTACTAACTTAGGTGCTTGGCCTTACTTGGCTGCATCGAGAGTGAGTCCTTACCAA
AAAATGCAGGTGTGGGACAAAGACAGCCTAGGCAAGATTGATTTCGACGCCCATTCATTGAGTGAAACCCACCTAGGTTC
GATTATCGAAAACGATGCCATCGCCTTTGCATTAGCCGAGCGCGCCAGTGAGTTTAGTGAGCTGACATATATCGAAAACC
AGCGTCTAGAGCGTATTGCCTTTGGAGAGCGTGAGGCTTGGTTAACCTTAGATAATGGCGACAACTTAAGCGCAGCGTTA
GTGGTCGCTGCGGATGGCGCTAATTCATGGGTGCGCGAGCAATGTAAAATCCCCATGACCTTCTGGGATTACAATCATCA
CGCTATTGTGGCAACTATACGCACCGAGTTGCCTCACGCTGGCACCGCAAGACAAGTATTCGACAGCGAAGGCCCATTAG
CCTTCTTGCCTTTATATGAAAAAGATCTCTGCTCAATTGTCTGGTCGGTATCTCCAGAGAAAGCCGAGCAATTGCTGGCA
TTAGATAAGGTAGACTTTGAACGTGCCCTTACCGCCGCCTTCGATGGCCGTCTAGGCATGTGCACCCTTGAGAGTGAGCG
TCAGTCGTTCCCGCTACGTATGCGTTACGCGCGTCACTTTGCACGGTCACGTCTGGTGTTAGCAGGCGATGCGGCGCACA
CCATACACCCACTAGCGGGGCAGGGAGTTAACTTAGGTTTCCTCGATGCGGCCAGCATAGTCGAGGTGGTGAGCGAGCTT
AAACAGCAGGGTAAAGATATTGGTGATTACCGCAACCTGCGCGATCTTGAGCGCTGGCGTAAGGCCGAAGCGTTAGAGAT
GATCACCGCAATGGAAGGCTTTAAGAGGCTATTCCAAGGCACTAATCCGATTAAGAAAGCCATCCGTGATCTGGGCTTAA
ATATCGTCGACAATTTTGCGCCATTGAAAACACTGTTTATTCAACAGGCGCTAGGCAACAAGACTAATCTACCTAAGCTG
TGTAAGCGGTCTGAAAGTTAA

Upstream 100 bases:

>100_bases
ATAGGCTAAGTACAACCGTCTCCATTAGCTAAGCATCATTATGGCAAGCTAGTGGCCGCGTAATTCACGCTATGAGCAGT
ATTTTTAGTAAGGGTAAAAG

Downstream 100 bases:

>100_bases
CAACTACAACTCATTAGTTAAGTCTAAATAAGTCTTTAATTTCAGGGGTTTGTTTTTGCAATTAGTTTACTTGCTGTTTT
TGTGTGAAAATTTCACATAT

Product: UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MLSTQTYDVAIVGGGMVGLATAIGLAMEGIKVVVIDAGQTQAVSGAPKLRVSAINKASQQLITNLGAWPYLAASRVSPYQ
KMQVWDKDSLGKIDFDAHSLSETHLGSIIENDAIAFALAERASEFSELTYIENQRLERIAFGEREAWLTLDNGDNLSAAL
VVAADGANSWVREQCKIPMTFWDYNHHAIVATIRTELPHAGTARQVFDSEGPLAFLPLYEKDLCSIVWSVSPEKAEQLLA
LDKVDFERALTAAFDGRLGMCTLESERQSFPLRMRYARHFARSRLVLAGDAAHTIHPLAGQGVNLGFLDAASIVEVVSEL
KQQGKDIGDYRNLRDLERWRKAEALEMITAMEGFKRLFQGTNPIKKAIRDLGLNIVDNFAPLKTLFIQQALGNKTNLPKL
CKRSES

Sequences:

>Translated_406_residues
MLSTQTYDVAIVGGGMVGLATAIGLAMEGIKVVVIDAGQTQAVSGAPKLRVSAINKASQQLITNLGAWPYLAASRVSPYQ
KMQVWDKDSLGKIDFDAHSLSETHLGSIIENDAIAFALAERASEFSELTYIENQRLERIAFGEREAWLTLDNGDNLSAAL
VVAADGANSWVREQCKIPMTFWDYNHHAIVATIRTELPHAGTARQVFDSEGPLAFLPLYEKDLCSIVWSVSPEKAEQLLA
LDKVDFERALTAAFDGRLGMCTLESERQSFPLRMRYARHFARSRLVLAGDAAHTIHPLAGQGVNLGFLDAASIVEVVSEL
KQQGKDIGDYRNLRDLERWRKAEALEMITAMEGFKRLFQGTNPIKKAIRDLGLNIVDNFAPLKTLFIQQALGNKTNLPKL
CKRSES
>Mature_406_residues
MLSTQTYDVAIVGGGMVGLATAIGLAMEGIKVVVIDAGQTQAVSGAPKLRVSAINKASQQLITNLGAWPYLAASRVSPYQ
KMQVWDKDSLGKIDFDAHSLSETHLGSIIENDAIAFALAERASEFSELTYIENQRLERIAFGEREAWLTLDNGDNLSAAL
VVAADGANSWVREQCKIPMTFWDYNHHAIVATIRTELPHAGTARQVFDSEGPLAFLPLYEKDLCSIVWSVSPEKAEQLLA
LDKVDFERALTAAFDGRLGMCTLESERQSFPLRMRYARHFARSRLVLAGDAAHTIHPLAGQGVNLGFLDAASIVEVVSEL
KQQGKDIGDYRNLRDLERWRKAEALEMITAMEGFKRLFQGTNPIKKAIRDLGLNIVDNFAPLKTLFIQQALGNKTNLPKL
CKRSES

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=414, Percent_Identity=31.4009661835749, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI32967307, Length=368, Percent_Identity=32.3369565217391, Blast_Score=151, Evalue=1e-36,
Organism=Escherichia coli, GI1789273, Length=397, Percent_Identity=54.1561712846348, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1786883, Length=393, Percent_Identity=33.587786259542, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1789274, Length=393, Percent_Identity=30.2798982188295, Blast_Score=169, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI25146631, Length=431, Percent_Identity=30.1624129930394, Blast_Score=187, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6321694, Length=457, Percent_Identity=26.0393873085339, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI19920760, Length=434, Percent_Identity=31.3364055299539, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44748; Mature: 44748

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTQTYDVAIVGGGMVGLATAIGLAMEGIKVVVIDAGQTQAVSGAPKLRVSAINKASQQ
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHH
LITNLGAWPYLAASRVSPYQKMQVWDKDSLGKIDFDAHSLSETHLGSIIENDAIAFALAE
HHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHH
RASEFSELTYIENQRLERIAFGEREAWLTLDNGDNLSAALVVAADGANSWVREQCKIPMT
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEECCCCHHHHHHCCCCEE
FWDYNHHAIVATIRTELPHAGTARQVFDSEGPLAFLPLYEKDLCSIVWSVSPEKAEQLLA
EEECCCCEEEEEEECCCCCCCCHHHHHCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHH
LDKVDFERALTAAFDGRLGMCTLESERQSFPLRMRYARHFARSRLVLAGDAAHTIHPLAG
HHHHHHHHHHHHHHCCCCEEEEECCHHHCCCHHHHHHHHHHHCCEEEECCCCHHCCCCCC
QGVNLGFLDAASIVEVVSELKQQGKDIGDYRNLRDLERWRKAEALEMITAMEGFKRLFQG
CCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TNPIKKAIRDLGLNIVDNFAPLKTLFIQQALGNKTNLPKLCKRSES
CCHHHHHHHHCCCHHHHCHHHHHHHHHHHHHCCCCCCHHHHHCCCC
>Mature Secondary Structure
MLSTQTYDVAIVGGGMVGLATAIGLAMEGIKVVVIDAGQTQAVSGAPKLRVSAINKASQQ
CCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHH
LITNLGAWPYLAASRVSPYQKMQVWDKDSLGKIDFDAHSLSETHLGSIIENDAIAFALAE
HHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHCCHHHHHHHH
RASEFSELTYIENQRLERIAFGEREAWLTLDNGDNLSAALVVAADGANSWVREQCKIPMT
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEECCCCHHHHHHCCCCEE
FWDYNHHAIVATIRTELPHAGTARQVFDSEGPLAFLPLYEKDLCSIVWSVSPEKAEQLLA
EEECCCCEEEEEEECCCCCCCCHHHHHCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHH
LDKVDFERALTAAFDGRLGMCTLESERQSFPLRMRYARHFARSRLVLAGDAAHTIHPLAG
HHHHHHHHHHHHHHCCCCEEEEECCHHHCCCHHHHHHHHHHHCCEEEECCCCHHCCCCCC
QGVNLGFLDAASIVEVVSELKQQGKDIGDYRNLRDLERWRKAEALEMITAMEGFKRLFQG
CCCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TNPIKKAIRDLGLNIVDNFAPLKTLFIQQALGNKTNLPKLCKRSES
CCHHHHHHHHCCCHHHHCHHHHHHHHHHHHHCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]