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The map label for this gene is purP [H]

Identifier: 157962904

GI number: 157962904

Start: 3785671

End: 3786960

Strand: Reverse

Name: purP [H]

Synonym: Spea_3086

Alternate gene names: 157962904

Gene position: 3786960-3785671 (Counterclockwise)

Preceding gene: 157962905

Following gene: 157962903

Centisome position: 73.18

GC content: 48.06

Gene sequence:

>1290_bases
ATGTTAGAAAAATTATTCAAATTAAAACAAAATCAAACAACGCTAAAGCAAGAAGTTATCGCAGGACTAACGACCTTCTT
GACCATGGCTTACATTATTTTCGTGAACCCTATGATGCTGGCCGATGCGGGCATGGATCATGGCGCCGTTTTTGTCGCAA
CTTGCTTAGCTGCCGCCATCGGTTGTTTAGTCATGGGCTTAGTGGCTAACTACCCGATTGCGCTGGCACCCGGTATGGGG
CTCAACGCCTTCTTTACTTACACGGTAGTAGGTGAGATGGGTTACTCGTGGGAGACGGCTTTAGGCGCCGTATTCCTGTC
TGGGATCTGCTTCTTAGTACTGTCTTTAGTGCGAATTCGCGAGTGGATTGTTAATAGCATTCCCATGTCGCTTCGTATCG
GCATTGCCGCTGGTATCGGTTTGTTCTTGGCCTTATTAGGCCTTAAAAGTGCCGGTATTGTGGTTTCTAGCCCTGCGACA
TTGGTGACCATGGGTGATATCACTTCCTTTCCAGCCGTTATGGCGGCATTAGGTTTCTTCCTGATTATCGCCATGGTGCA
TCACGGGATGAAGTCTGCGGTGGTGATTAGCATTCTGGCCATTACCTTACTGGGCTTACTGTTTGGCGATGTGCAGTATC
AAGGTATTGTTTCTGCGCCGCCTTCAATCATGCCGACATTTATGAAAATGGACCTGTCTGGCGTGCTTGAAGTCAGCATG
CTATCTGTGGTGTTTGCATTTTTGTTTGTCGATTTGTTTGATACCTCGGGTACCTTAGTTGCAGTCGCTCAGCGTGGTGG
CTTCTTAGATGATAAAGGCCGTTTACCCCGCTTAAATCGTGCGTTAACGGCTGACAGCACCGCGACTATCGCCGGTGCTA
TGCTGGGTACGTCAACTACGACCAGTTATGTTGAAAGTACCGCTGGCGTCAGTGCCGGTGGCCGCACAGGTTTAACTGCC
GTAGTTGTGGGAGTACTGTTTTTAGGTGCGTTATTTATCTCGCCATTAGCCGGCATGGTACCTGCGTACGCAACGGCGGG
TACACTTTTTTACGTGGCTATTCTTATGATGTCTGGCCTAGTGCATGTTGAATGGGAAGATATTACCGAAGCCGCTCCTG
TTGTGGTTGTATGCATATTGATGCCGCTGACCTTCTCGATTGCAACGGGGATCGCCATGGGCTTTATCTCTTATGCGCTG
ATCAAGTTAATGAGTGGCCGCTACAAAGATTTAAGCCTAGGTGTGCTGATCTTAGCCGCATTGTTTATTGCTAAATTTAT
CTATGGTTAA

Upstream 100 bases:

>100_bases
AATCAAACAATGATTGTTTCAGAAATAGAAAAGTCTTACTTAGGTTAGCAATGAGTACCCCCTACAAATCAATATAATAA
AAACCAAGGAACCTTGTTCC

Downstream 100 bases:

>100_bases
CTGTACTCATTAGCAGTTGCTCTGCTTACTTAAAGCCACACCGAGTGTGGCTTTTTTATTTTCAGCTTAAGCATTTTGTT
CGATGATAGTTTGAGCGTGG

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLEKLFKLKQNQTTLKQEVIAGLTTFLTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAIGCLVMGLVANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLVLSLVRIREWIVNSIPMSLRIGIAAGIGLFLALLGLKSAGIVVSSPAT
LVTMGDITSFPAVMAALGFFLIIAMVHHGMKSAVVISILAITLLGLLFGDVQYQGIVSAPPSIMPTFMKMDLSGVLEVSM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDDKGRLPRLNRALTADSTATIAGAMLGTSTTTSYVESTAGVSAGGRTGLTA
VVVGVLFLGALFISPLAGMVPAYATAGTLFYVAILMMSGLVHVEWEDITEAAPVVVVCILMPLTFSIATGIAMGFISYAL
IKLMSGRYKDLSLGVLILAALFIAKFIYG

Sequences:

>Translated_429_residues
MLEKLFKLKQNQTTLKQEVIAGLTTFLTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAIGCLVMGLVANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLVLSLVRIREWIVNSIPMSLRIGIAAGIGLFLALLGLKSAGIVVSSPAT
LVTMGDITSFPAVMAALGFFLIIAMVHHGMKSAVVISILAITLLGLLFGDVQYQGIVSAPPSIMPTFMKMDLSGVLEVSM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDDKGRLPRLNRALTADSTATIAGAMLGTSTTTSYVESTAGVSAGGRTGLTA
VVVGVLFLGALFISPLAGMVPAYATAGTLFYVAILMMSGLVHVEWEDITEAAPVVVVCILMPLTFSIATGIAMGFISYAL
IKLMSGRYKDLSLGVLILAALFIAKFIYG
>Mature_429_residues
MLEKLFKLKQNQTTLKQEVIAGLTTFLTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAIGCLVMGLVANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLVLSLVRIREWIVNSIPMSLRIGIAAGIGLFLALLGLKSAGIVVSSPAT
LVTMGDITSFPAVMAALGFFLIIAMVHHGMKSAVVISILAITLLGLLFGDVQYQGIVSAPPSIMPTFMKMDLSGVLEVSM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDDKGRLPRLNRALTADSTATIAGAMLGTSTTTSYVESTAGVSAGGRTGLTA
VVVGVLFLGALFISPLAGMVPAYATAGTLFYVAILMMSGLVHVEWEDITEAAPVVVVCILMPLTFSIATGIAMGFISYAL
IKLMSGRYKDLSLGVLILAALFIAKFIYG

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=428, Percent_Identity=52.5700934579439, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI87082309, Length=426, Percent_Identity=50.9389671361502, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI1790499, Length=425, Percent_Identity=38.8235294117647, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI48994909, Length=435, Percent_Identity=38.1609195402299, Blast_Score=267, Evalue=9e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45005; Mature: 45005

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKLFKLKQNQTTLKQEVIAGLTTFLTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAI
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GCLVMGLVANYPIALAPGMGLNAFFTYTVVGEMGYSWETALGAVFLSGICFLVLSLVRIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWIVNSIPMSLRIGIAAGIGLFLALLGLKSAGIVVSSPATLVTMGDITSFPAVMAALGFF
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHH
LIIAMVHHGMKSAVVISILAITLLGLLFGDVQYQGIVSAPPSIMPTFMKMDLSGVLEVSM
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDDKGRLPRLNRALTADSTATIAGAMLGTSTT
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCHH
TSYVESTAGVSAGGRTGLTAVVVGVLFLGALFISPLAGMVPAYATAGTLFYVAILMMSGL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VHVEWEDITEAAPVVVVCILMPLTFSIATGIAMGFISYALIKLMSGRYKDLSLGVLILAA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LFIAKFIYG
HHHHHHHCC
>Mature Secondary Structure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HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]