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The map label for this gene is pyrH [H]

Identifier: 157962702

GI number: 157962702

Start: 3521496

End: 3522224

Strand: Reverse

Name: pyrH [H]

Synonym: Spea_2883

Alternate gene names: 157962702

Gene position: 3522224-3521496 (Counterclockwise)

Preceding gene: 157962703

Following gene: 157962701

Centisome position: 68.07

GC content: 44.72

Gene sequence:

>729_bases
ATGAGTACCAATCCTAAACCTGCTTTTCGTCGTGTTCTTTTAAAACTAAGTGGTGAAGCCCTAATGGGTGAAGAAGGCTT
CGGCATTGATCCTAAAGTGCTTGATCGTATGGGGCAGGAGATCAAAGAGCTAGTTGAGCTAGGTATTCAAGTGGGTGTTG
TCATTGGCGGTGGTAACTTGTTCCGTGGCGAAGGTCTAGCGAACGCGGGTATGAACCGTGTAGTGGGCGATCACATGGGC
ATGTTGGCAACAGTGATGAACGGCTTAGCAATGCGTGATTCGTTGCACCGTGCATATGTAAATGCACGTTTAATGTCAGC
TATTCCGCTTAAAGGCGTGTGTGATGACTATAACTGGGCTGAAGCAATTAGTTTGCTTAAATCAGGCCGTGTTGTTATTT
TTGCTGCTGGTACAGGTAACCCATTCTGTACGACTGACTCTGCTGCGTGTTTACGCGGTATCGAGATTGAAGCAGAAGTA
GTGATTAAAGGCACCAAAGTTGACGGCGTTTATTCAGATGATCCAGTTAAAAATCCAGAAGCCGTCAAGTATGATGTTAT
GGGGTACAATGAAGTACTCGAAAAAGAATTGAAAGTAATGGATTTGGCTGCATTCACTATGGCCAGAGACCATAATATGC
CATTGCTCGTTTTTAACATGAATAAACCTGGTGCACTGCGCCGCGTTATCATGGGCGAGCAAGAAGGCACAATGATTAAA
GCTGTTTAA

Upstream 100 bases:

>100_bases
TCTTATCGTATATACTCGAATAGTTTTTGTCTTGTTAAGTAACATTCGGTAAAACTATTCCAGTGTAGATCCCCTATCGC
CATAATCAGGACTAATAAAT

Downstream 100 bases:

>100_bases
GCTATATTTAGTGACTTAAAAGGACATATAACGTGATAAACGAAATTAAAAGCGATGCGCAAACTCGCATGGACAAGTGT
GTTGAGTCGACAAAAACTCA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSTNPKPAFRRVLLKLSGEALMGEEGFGIDPKVLDRMGQEIKELVELGIQVGVVIGGGNLFRGEGLANAGMNRVVGDHMG
MLATVMNGLAMRDSLHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEV
VIKGTKVDGVYSDDPVKNPEAVKYDVMGYNEVLEKELKVMDLAAFTMARDHNMPLLVFNMNKPGALRRVIMGEQEGTMIK
AV

Sequences:

>Translated_242_residues
MSTNPKPAFRRVLLKLSGEALMGEEGFGIDPKVLDRMGQEIKELVELGIQVGVVIGGGNLFRGEGLANAGMNRVVGDHMG
MLATVMNGLAMRDSLHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEV
VIKGTKVDGVYSDDPVKNPEAVKYDVMGYNEVLEKELKVMDLAAFTMARDHNMPLLVFNMNKPGALRRVIMGEQEGTMIK
AV
>Mature_241_residues
STNPKPAFRRVLLKLSGEALMGEEGFGIDPKVLDRMGQEIKELVELGIQVGVVIGGGNLFRGEGLANAGMNRVVGDHMGM
LATVMNGLAMRDSLHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVV
IKGTKVDGVYSDDPVKNPEAVKYDVMGYNEVLEKELKVMDLAAFTMARDHNMPLLVFNMNKPGALRRVIMGEQEGTMIKA
V

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=239, Percent_Identity=79.9163179916318, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26177; Mature: 26046

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPKPAFRRVLLKLSGEALMGEEGFGIDPKVLDRMGQEIKELVELGIQVGVVIGGGNL
CCCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
FRGEGLANAGMNRVVGDHMGMLATVMNGLAMRDSLHRAYVNARLMSAIPLKGVCDDYNWA
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVIKGTKVDGVYSDDPVKNPE
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEEEEEECEECCEECCCCCCCCC
AVKYDVMGYNEVLEKELKVMDLAAFTMARDHNMPLLVFNMNKPGALRRVIMGEQEGTMIK
CEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEE
AV
EC
>Mature Secondary Structure 
STNPKPAFRRVLLKLSGEALMGEEGFGIDPKVLDRMGQEIKELVELGIQVGVVIGGGNL
CCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
FRGEGLANAGMNRVVGDHMGMLATVMNGLAMRDSLHRAYVNARLMSAIPLKGVCDDYNWA
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVIKGTKVDGVYSDDPVKNPE
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEEEEEECEECCEECCCCCCCCC
AVKYDVMGYNEVLEKELKVMDLAAFTMARDHNMPLLVFNMNKPGALRRVIMGEQEGTMIK
CEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEE
AV
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA