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The map label for this gene is frr [H]

Identifier: 157962701

GI number: 157962701

Start: 3520906

End: 3521463

Strand: Reverse

Name: frr [H]

Synonym: Spea_2882

Alternate gene names: 157962701

Gene position: 3521463-3520906 (Counterclockwise)

Preceding gene: 157962702

Following gene: 157962700

Centisome position: 68.05

GC content: 44.09

Gene sequence:

>558_bases
GTGATAAACGAAATTAAAAGCGATGCGCAAACTCGCATGGACAAGTGTGTTGAGTCGACAAAAACTCAAATGGCTAAAGT
TCGTACCGGCCGTGCACATCCAAGCTTATTGGATACCATCCAAGTACCTTACTACGGTTCGCTCACTCCGCTTAAGCAAG
TTGCAAGTGTATCTATTGGCGATGCGCGTACATTAACTGTATCAGTATTCGACCGTACTATGATTGCAGCTGTTGAAAAA
GCAATCATGAGTTCAGATCTTGGTCTGAACCCAATGTCAGCGGGGGCGACAATTCGCATTCCATTACCTGCATTGACTGA
AGAGCGTCGTAAAGATCTTATTAAGGTTGTTCGCGCTGAAGCCGAGAACGGCCGTATTGCGATTCGTAACGTACGTCGTG
ACGCTAACTCAAATGTAAAAGAGTTAGAGAAAGAGAAAGAGTGTACAGAAGATGATGTTCGTCGCAGTGAAGATGACGTG
CAGAAGTTAACTGATGCTCACATCAAGCTGATTGATGAAATTCTGGCTGCTAAAGAAAAGGAACTGATGGAGTTCTAA

Upstream 100 bases:

>100_bases
ATAAACCTGGTGCACTGCGCCGCGTTATCATGGGCGAGCAAGAAGGCACAATGATTAAAGCTGTTTAAGCTATATTTAGT
GACTTAAAAGGACATATAAC

Downstream 100 bases:

>100_bases
ATAGAGCTCTTCAGTTAAAGGGGTGTTCACCGTTTGAGTTGGTTTTTAATACGCTTTTGAGTGTTTCTTGCTTTTTTAGT
GAGAGATAGCAAACTTTTCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIGDARTLTVSVFDRTMIAAVEK
AIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAEAENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDV
QKLTDAHIKLIDEILAAKEKELMEF

Sequences:

>Translated_185_residues
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIGDARTLTVSVFDRTMIAAVEK
AIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAEAENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDV
QKLTDAHIKLIDEILAAKEKELMEF
>Mature_185_residues
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIGDARTLTVSVFDRTMIAAVEK
AIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAEAENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDV
QKLTDAHIKLIDEILAAKEKELMEF

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=29.8850574712644, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=30.6666666666667, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=68.1081081081081, Blast_Score=258, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24661488, Length=175, Percent_Identity=32.5714285714286, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20668; Mature: 20668

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCCC
DARTLTVSVFDRTMIAAVEKAIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAE
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
AENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDVQKLTDAHIKLIDEILAAKEK
CCCCCEEEHHHHHCCCCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMEF
HHHCC
>Mature Secondary Structure
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHCCCC
DARTLTVSVFDRTMIAAVEKAIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAE
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
AENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDVQKLTDAHIKLIDEILAAKEK
CCCCCEEEHHHHHCCCCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMEF
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA