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The map label for this gene is etfA [H]

Identifier: 157962673

GI number: 157962673

Start: 3485522

End: 3486445

Strand: Reverse

Name: etfA [H]

Synonym: Spea_2854

Alternate gene names: 157962673

Gene position: 3486445-3485522 (Counterclockwise)

Preceding gene: 157962674

Following gene: 157962672

Centisome position: 67.38

GC content: 48.59

Gene sequence:

>924_bases
ATGGCAATTTTAATATTAGCAGAACACGATAACGCCAGTTTAAAGCTAGATACCGCTAAAGTGGTTGCATGCGGTCAAGC
CATTGGTGGAGATATAGACGTATTAGTAGTCGGACATAACTGTGATGGCGTGGCAAGCGAAGCGCAACAGTTAACAGGTG
TGCGTAATGTACTGCTTGCCGATTCAGCATCGTATGCCAATCATCTCGCTGAAAATATTTCTGAACTAGTGCTTGGCGTC
GCGTCTGATTATGAGCATGTGTTAGCGCCAGCCTCAAGTTTTGGTAAAGATGTGCTGCCGCGAGTGGCTGCACTTTTGGA
TGTGTCTCAACTCTCAGAAGTTGTAGAAGTGGTTAGCAGCGATACATTCGTCCGTCCTATCTACGCCGGTAGCGTGCTTG
CAACGGTTCAGAGCCTAGACGATAAGAAAGTGATGACGGTACGTTCGAGTGCGTTTGATGCTGTCGCAACAGATGGCAAT
GCAGAGCGTGTGCCCCTTGCCCAAGACATGGCGGCACAATCTGAGTTTGTTGAACAGAGCCTAACTGAATCTGAGCGTCC
AGAGCTAGGCAGTGCGTCGGTAGTTGTTTCAGGCGGCCGTGCCCTAGGTAACAGCGAAAACTTTGGTATTCTTGAGCAAC
TAGCAGATAAGCTAGGTGGCGCCGTTGGTGCATCTCGCGCTGCAGTTGACGCAGGCTTTGTACCAAACGACTTACAGGTG
GGTCAGACTGGTAAGATAGTTGCGCCTGACTTGTATATTGCCGTCGGTATTTCTGGTGCTATCCAACACTTAGCAGGCAT
GAAAGACTCTAAGGTGATAGTGGCAATTAACAAAGACCCTGAGGCGCCGATTTTCCAAATTGCGGATTACGGTTTAGAGG
CGGATCTGTTTGAAGCGGTACCTGAATTATTAGCCAAGCTTTAA

Upstream 100 bases:

>100_bases
TCCTTAAGGTTGCCCCACCAGCTGAGCGTAGCGGTGGTGTGATGGTTGCGTCTGTAGAAGAGTTGGTTGAAAAGTTAAAG
AATGAAGCGAAGGTGATCTA

Downstream 100 bases:

>100_bases
TCTAATGATTATATCCTGTGCAACACCTATGCAGCGTGAAGTTGTTTCACACTAGTAGTCAGCTTGTTAGTGGATGTGAG
TTAATTTGGTATTGTTCGTG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MAILILAEHDNASLKLDTAKVVACGQAIGGDIDVLVVGHNCDGVASEAQQLTGVRNVLLADSASYANHLAENISELVLGV
ASDYEHVLAPASSFGKDVLPRVAALLDVSQLSEVVEVVSSDTFVRPIYAGSVLATVQSLDDKKVMTVRSSAFDAVATDGN
AERVPLAQDMAAQSEFVEQSLTESERPELGSASVVVSGGRALGNSENFGILEQLADKLGGAVGASRAAVDAGFVPNDLQV
GQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAVPELLAKL

Sequences:

>Translated_307_residues
MAILILAEHDNASLKLDTAKVVACGQAIGGDIDVLVVGHNCDGVASEAQQLTGVRNVLLADSASYANHLAENISELVLGV
ASDYEHVLAPASSFGKDVLPRVAALLDVSQLSEVVEVVSSDTFVRPIYAGSVLATVQSLDDKKVMTVRSSAFDAVATDGN
AERVPLAQDMAAQSEFVEQSLTESERPELGSASVVVSGGRALGNSENFGILEQLADKLGGAVGASRAAVDAGFVPNDLQV
GQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAVPELLAKL
>Mature_306_residues
AILILAEHDNASLKLDTAKVVACGQAIGGDIDVLVVGHNCDGVASEAQQLTGVRNVLLADSASYANHLAENISELVLGVA
SDYEHVLAPASSFGKDVLPRVAALLDVSQLSEVVEVVSSDTFVRPIYAGSVLATVQSLDDKKVMTVRSSAFDAVATDGNA
ERVPLAQDMAAQSEFVEQSLTESERPELGSASVVVSGGRALGNSENFGILEQLADKLGGAVGASRAAVDAGFVPNDLQVG
QTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAVPELLAKL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=304, Percent_Identity=55.2631578947368, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI189181759, Length=264, Percent_Identity=57.9545454545455, Blast_Score=296, Evalue=2e-80,
Organism=Escherichia coli, GI1786226, Length=230, Percent_Identity=34.3478260869565, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787990, Length=121, Percent_Identity=41.3223140495868, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082157, Length=220, Percent_Identity=31.3636363636364, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=310, Percent_Identity=51.9354838709677, Blast_Score=311, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6325261, Length=293, Percent_Identity=45.0511945392491, Blast_Score=248, Evalue=7e-67,
Organism=Drosophila melanogaster, GI17136898, Length=310, Percent_Identity=59.6774193548387, Blast_Score=349, Evalue=1e-96,
Organism=Drosophila melanogaster, GI24652801, Length=310, Percent_Identity=59.6774193548387, Blast_Score=349, Evalue=1e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31791; Mature: 31660

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILILAEHDNASLKLDTAKVVACGQAIGGDIDVLVVGHNCDGVASEAQQLTGVRNVLLA
CEEEEEEECCCCEEEECHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHC
DSASYANHLAENISELVLGVASDYEHVLAPASSFGKDVLPRVAALLDVSQLSEVVEVVSS
CCHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DTFVRPIYAGSVLATVQSLDDKKVMTVRSSAFDAVATDGNAERVPLAQDMAAQSEFVEQS
CCEEEHHHHHHHHHHHHHCCCCCEEEEHHCCCHHEECCCCCCCCCHHHHHHHHHHHHHHH
LTESERPELGSASVVVSGGRALGNSENFGILEQLADKLGGAVGASRAAVDAGFVPNDLQV
HHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCEE
GQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAV
CCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCHHHHHHH
PELLAKL
HHHHHCC
>Mature Secondary Structure 
AILILAEHDNASLKLDTAKVVACGQAIGGDIDVLVVGHNCDGVASEAQQLTGVRNVLLA
EEEEEEECCCCEEEECHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHC
DSASYANHLAENISELVLGVASDYEHVLAPASSFGKDVLPRVAALLDVSQLSEVVEVVSS
CCHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DTFVRPIYAGSVLATVQSLDDKKVMTVRSSAFDAVATDGNAERVPLAQDMAAQSEFVEQS
CCEEEHHHHHHHHHHHHHCCCCCEEEEHHCCCHHEECCCCCCCCCHHHHHHHHHHHHHHH
LTESERPELGSASVVVSGGRALGNSENFGILEQLADKLGGAVGASRAAVDAGFVPNDLQV
HHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCCEE
GQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQIADYGLEADLFEAV
CCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCHHHHHHH
PELLAKL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]