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The map label for this gene is yqjI [H]

Identifier: 157962615

GI number: 157962615

Start: 3411130

End: 3412665

Strand: Reverse

Name: yqjI [H]

Synonym: Spea_2794

Alternate gene names: 157962615

Gene position: 3412665-3411130 (Counterclockwise)

Preceding gene: 157962616

Following gene: 157962613

Centisome position: 65.95

GC content: 47.98

Gene sequence:

>1536_bases
ATGAATAACCAATCTAATCTTTTCGATATAGGTGTTATTGGCTTAGGCGTAATGGGCAAGAATCTAGCGCTTAATATCGC
TGATAACCAATATCGCGTCGCTGCATTTGACCTTGATGAAATTAAAGTGCAAGACACTGTCAATCAAGAGAAACTTGAAC
GTCAACAATACCTAAAACAGATAACAGAGCCACGCATCCTCGGCTGTAACAATCTTTCTGAAATGTTATCTAAATTAGAA
AAACCTCGAGTGCTGTTGCTATCGGTTCCAGCGGGTGCGCCTGTAGGTGGTGCATGTCAGTCCCTGATTGATGCCGGAAT
TGAGAGCGATGATATCGTTATCGATACAGGTAATAGTCTGTGGACAGATACTGTCGAGCGAGAACAGCGCTACGCCGATG
ATTTCTTATTTTTTAGCTGCGCCGTTTCTGGCGGTGAAGTCGGCGCCCGTTTTGGCCCCTCATTGATGCCAAGCGGTAGC
TTAAAGGCCTGGAATAGAATTGAACCGATTTGGCAAGCCATTGCCGCTAAGGTCGATGCAAAAACAGGTTTACCTATCGA
ACGGTTTGAGCCGGGAAACCCTGTTAAAGAGGGCGAACCTTGCACTACTTATATCGGTCCTGCTGGGTCAGGTCATTATG
TAAAAATGGTACATAACGGCATCGAATACGCCGATATGCAGCTGATCTGTGAGGCTTACCAGCTACTAAATCAAGGCTTA
GGGTTAACCCCGAGTGAAGTGGCTGATGTGTTTGAGCGCTGGGATCAAGGTAGCTTAAATAGCTACTTGATGCAGATCAG
CGCAAAGGTGCTTAAGCAAGCAGACCCATTAACGGGCGCGCCGCTGGTGGAGATGATCTTAGATAAGGCGGGGCAAAAAG
GCACAGGCCTTTGGACTGCGGTAAGCAGCCTGCAAATAGGCTGCCCGGCGCCAACCATTGCCGAAGCCGTATATGCTCGT
GCGCTGAGCACTCAAAAAACTCAGCGTCAGCAGTTAAGTCAGCAGTTATCGGGGCCGAGTAAAGCCCTAGGCAATATTGA
TAAACAAGCGTTTATCGAACAGCTGGAAAGTGCACTCTATTGCGCTAAAGTATCCTGTTACGCTCAAGGTTTTCAGCTGA
TGGCTATGCAAGCTAAAGAGCAGGGCTGGCAGTTAGATTTTGCCGAGATAGCTAAGATCTGGCGAGCAGGCTGTATTATT
CGCGCCACATTCTTACAGTCGATTACTGAGGCTTATCAGCAAGATAGCTCGCTTGAGAACTTGTTGCTGGCGGAAGCTTT
CTCAAAGGCCTTGTCTGTAAAGCAGCAAGATTGGCGAGTGGCGGTATCGACTGCGGTACTCAGTGGTATTCCGGCTCCTT
GTATCAGCTCGGCGTTGGCTTATTACGATAGCTATCGCTGCGAAACTTTGCCCGCGAGCTTACTTCAGGGGCAGCGTGAC
TTCTTTGGTGCCCATACTTTTGAACGTATCGATAAGCCTGCAGGTGAGAAGTTCCACTTAAACTGGAGTGGCGATCTCAG
CTTAATTAAGGTGTAA

Upstream 100 bases:

>100_bases
AATCCATAACAAATAACCCTATCAATCAAGCAAGCGCAATGACGTAAGCTGAACAAAAAATAGATAGGGAACTCTCTGTG
ACCTGCGGAATATAATTTAA

Downstream 100 bases:

>100_bases
CCATATTTCAGGACAAGACATAGATAATAAAAAAGCCTATCAAATTGATAGGCTTTTTTGTCATCGAGTCTCGTACAGAG
TTTAGTTAATGCTAGAAGTT

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MNNQSNLFDIGVIGLGVMGKNLALNIADNQYRVAAFDLDEIKVQDTVNQEKLERQQYLKQITEPRILGCNNLSEMLSKLE
KPRVLLLSVPAGAPVGGACQSLIDAGIESDDIVIDTGNSLWTDTVEREQRYADDFLFFSCAVSGGEVGARFGPSLMPSGS
LKAWNRIEPIWQAIAAKVDAKTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
GLTPSEVADVFERWDQGSLNSYLMQISAKVLKQADPLTGAPLVEMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYAR
ALSTQKTQRQQLSQQLSGPSKALGNIDKQAFIEQLESALYCAKVSCYAQGFQLMAMQAKEQGWQLDFAEIAKIWRAGCII
RATFLQSITEAYQQDSSLENLLLAEAFSKALSVKQQDWRVAVSTAVLSGIPAPCISSALAYYDSYRCETLPASLLQGQRD
FFGAHTFERIDKPAGEKFHLNWSGDLSLIKV

Sequences:

>Translated_511_residues
MNNQSNLFDIGVIGLGVMGKNLALNIADNQYRVAAFDLDEIKVQDTVNQEKLERQQYLKQITEPRILGCNNLSEMLSKLE
KPRVLLLSVPAGAPVGGACQSLIDAGIESDDIVIDTGNSLWTDTVEREQRYADDFLFFSCAVSGGEVGARFGPSLMPSGS
LKAWNRIEPIWQAIAAKVDAKTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
GLTPSEVADVFERWDQGSLNSYLMQISAKVLKQADPLTGAPLVEMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYAR
ALSTQKTQRQQLSQQLSGPSKALGNIDKQAFIEQLESALYCAKVSCYAQGFQLMAMQAKEQGWQLDFAEIAKIWRAGCII
RATFLQSITEAYQQDSSLENLLLAEAFSKALSVKQQDWRVAVSTAVLSGIPAPCISSALAYYDSYRCETLPASLLQGQRD
FFGAHTFERIDKPAGEKFHLNWSGDLSLIKV
>Mature_511_residues
MNNQSNLFDIGVIGLGVMGKNLALNIADNQYRVAAFDLDEIKVQDTVNQEKLERQQYLKQITEPRILGCNNLSEMLSKLE
KPRVLLLSVPAGAPVGGACQSLIDAGIESDDIVIDTGNSLWTDTVEREQRYADDFLFFSCAVSGGEVGARFGPSLMPSGS
LKAWNRIEPIWQAIAAKVDAKTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
GLTPSEVADVFERWDQGSLNSYLMQISAKVLKQADPLTGAPLVEMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYAR
ALSTQKTQRQQLSQQLSGPSKALGNIDKQAFIEQLESALYCAKVSCYAQGFQLMAMQAKEQGWQLDFAEIAKIWRAGCII
RATFLQSITEAYQQDSSLENLLLAEAFSKALSVKQQDWRVAVSTAVLSGIPAPCISSALAYYDSYRCETLPASLLQGQRD
FFGAHTFERIDKPAGEKFHLNWSGDLSLIKV

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=497, Percent_Identity=46.6800804828974, Blast_Score=430, Evalue=1e-120,
Organism=Escherichia coli, GI1788341, Length=494, Percent_Identity=45.1417004048583, Blast_Score=409, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17542558, Length=502, Percent_Identity=46.4143426294821, Blast_Score=438, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321695, Length=504, Percent_Identity=45.4365079365079, Blast_Score=445, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321977, Length=504, Percent_Identity=44.8412698412698, Blast_Score=424, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24639279, Length=497, Percent_Identity=44.466800804829, Blast_Score=402, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 55838; Mature: 55838

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQSNLFDIGVIGLGVMGKNLALNIADNQYRVAAFDLDEIKVQDTVNQEKLERQQYLKQ
CCCCCCEEEEHHHHHCCCCCCEEEEECCCCEEEEEECHHHHHHHHHCCHHHHHHHHHHHH
ITEPRILGCNNLSEMLSKLEKPRVLLLSVPAGAPVGGACQSLIDAGIESDDIVIDTGNSL
HCCCCEECCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCCH
WTDTVEREQRYADDFLFFSCAVSGGEVGARFGPSLMPSGSLKAWNRIEPIWQAIAAKVDA
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
KTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
CCCCCHHCCCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHCCC
GLTPSEVADVFERWDQGSLNSYLMQISAKVLKQADPLTGAPLVEMILDKAGQKGTGLWTA
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHH
VSSLQIGCPAPTIAEAVYARALSTQKTQRQQLSQQLSGPSKALGNIDKQAFIEQLESALY
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHH
CAKVSCYAQGFQLMAMQAKEQGWQLDFAEIAKIWRAGCIIRATFLQSITEAYQQDSSLEN
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LLLAEAFSKALSVKQQDWRVAVSTAVLSGIPAPCISSALAYYDSYRCETLPASLLQGQRD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHCCHHHHCCCHH
FFGAHTFERIDKPAGEKFHLNWSGDLSLIKV
HHHHHHHHHHCCCCCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MNNQSNLFDIGVIGLGVMGKNLALNIADNQYRVAAFDLDEIKVQDTVNQEKLERQQYLKQ
CCCCCCEEEEHHHHHCCCCCCEEEEECCCCEEEEEECHHHHHHHHHCCHHHHHHHHHHHH
ITEPRILGCNNLSEMLSKLEKPRVLLLSVPAGAPVGGACQSLIDAGIESDDIVIDTGNSL
HCCCCEECCCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCEEEECCCCH
WTDTVEREQRYADDFLFFSCAVSGGEVGARFGPSLMPSGSLKAWNRIEPIWQAIAAKVDA
HHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
KTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQLLNQGL
CCCCCHHCCCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHCCC
GLTPSEVADVFERWDQGSLNSYLMQISAKVLKQADPLTGAPLVEMILDKAGQKGTGLWTA
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHH
VSSLQIGCPAPTIAEAVYARALSTQKTQRQQLSQQLSGPSKALGNIDKQAFIEQLESALY
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHH
CAKVSCYAQGFQLMAMQAKEQGWQLDFAEIAKIWRAGCIIRATFLQSITEAYQQDSSLEN
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LLLAEAFSKALSVKQQDWRVAVSTAVLSGIPAPCISSALAYYDSYRCETLPASLLQGQRD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHCCHHHHCCCHH
FFGAHTFERIDKPAGEKFHLNWSGDLSLIKV
HHHHHHHHHHCCCCCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]