Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 157962585

GI number: 157962585

Start: 3377256

End: 3378335

Strand: Reverse

Name: mrdB [H]

Synonym: Spea_2764

Alternate gene names: 157962585

Gene position: 3378335-3377256 (Counterclockwise)

Preceding gene: 157962586

Following gene: 157962584

Centisome position: 65.29

GC content: 43.43

Gene sequence:

>1080_bases
ATGTTTAAATATACACCTCGAATTGACTTCCCTTTACTACTCGCGATTTCGTTGTTGATTCTGCTTGGCTCCCTAACGGT
ATGGAGTGCTAGCGGTTTCAGTGAATCTATTCTAGAGCGACACCTTGTTCGAGCTGTTATGGCGATAAGCTGCATTGTTG
TCATGTCAGTCATCCCACCGTTAAGTTATAAACGAGCTACCCCTTATCTATATGCATCTGCAGTCATTCTCCTGCTCGGA
GTCATTTTTGCTGGTGATAGCACTAACGGCTCTCAACGCTGGTTGGTTATTGGTCCTATACGATTCCAGCCGTCGGAGTT
AGTCAAGGTTGCTATCCCCTTGATGGTTGCATGGATTTTAGCAGCCGAAGGTGGGCGACCTGATATTAAAAAAATCACCA
TCTGTCTACTTGTTACTTCTGTTCCGGCGGGATTGATATTTATTCAGCCAGATCTGGATGGTGCAATATTTACAGTTATC
TACGCGCTGTTTGTTTTGTACTTTGCCGGAATGAGTTGGAAAATTATTGGTTCGTTTATCGGTGGGGTCGCGATTACTAT
CCCTATGTTGTGGTTTTTTGTCATGGAGGCCTATCAGAAAAAACGTGTGACTCAATTTTTGGATCCAGAATCCGATCCCC
TTGGTGCGGGTTACCAAATTATTCAATCATTGATTGCAATTGGTTCAGGGGGAATGCATGGAAAAGGTTGGACGAATGCA
ACGCAGGGGCAACTTGGATTCATCCCGGAAAGTCACACTGACTTTATTTTCTCAACCTATGCTGAGCAGTGGGGTTTTAT
CGGATGCTTACTCTTGGTAGGGCTTTATTTGTTTATTACAGGACGAGTCATTTGGCTAGCTTATCAATGTAAGTCGTCAT
TCAATCGTTTAGTCAGTGCCACTTTTGCACTTAGTTTCTTCTTATATGCCTTTATTAATATGGGGATGGTGAGCGGTATA
CTGCCAGTAATGGGCAGCCCATTGCCCTTTTTTAGCTATGGTGGCACAGCGATGATCACCCAAGGGATCTGTTTCGGCAT
CATAATGTCACTTTGTCTACAAAAGTCATATAAACCCTAA

Upstream 100 bases:

>100_bases
TTAAACAAGCAGATTTTAATAATAAAAAAACAGTTTATACTCTCCGCCATTATGAGCCCCGGTTGCTTGCCACTCAGCTT
GATGTTGAATGAAGATAGAT

Downstream 100 bases:

>100_bases
AGTATACTTGTTCTCTTTAGACACCTTTTAGGTGTGGGCTGTTGCTAGGTTACGTGATCATGATCACGCTTATTGGTGTG
AGTGATCGCTTTGTCAGCAC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESILERHLVRAVMAISCIVVMSVIPPLSYKRATPYLYASAVILLLG
VIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMVAWILAAEGGRPDIKKITICLLVTSVPAGLIFIQPDLDGAIFTVI
YALFVLYFAGMSWKIIGSFIGGVAITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKGWTNA
TQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCKSSFNRLVSATFALSFFLYAFINMGMVSGI
LPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKSYKP

Sequences:

>Translated_359_residues
MFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESILERHLVRAVMAISCIVVMSVIPPLSYKRATPYLYASAVILLLG
VIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMVAWILAAEGGRPDIKKITICLLVTSVPAGLIFIQPDLDGAIFTVI
YALFVLYFAGMSWKIIGSFIGGVAITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKGWTNA
TQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCKSSFNRLVSATFALSFFLYAFINMGMVSGI
LPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKSYKP
>Mature_359_residues
MFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESILERHLVRAVMAISCIVVMSVIPPLSYKRATPYLYASAVILLLG
VIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMVAWILAAEGGRPDIKKITICLLVTSVPAGLIFIQPDLDGAIFTVI
YALFVLYFAGMSWKIIGSFIGGVAITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKGWTNA
TQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCKSSFNRLVSATFALSFFLYAFINMGMVSGI
LPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKSYKP

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=333, Percent_Identity=47.7477477477478, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI1786277, Length=307, Percent_Identity=31.5960912052117, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 39337; Mature: 39337

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESILERHLVRAVMAISCIVVMSVIPP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSYKRATPYLYASAVILLLGVIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMVAWIL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
AAEGGRPDIKKITICLLVTSVPAGLIFIQPDLDGAIFTVIYALFVLYFAGMSWKIIGSFI
HCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
GGVAITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKGWTNA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
TQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCKSSFNRLVSA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFALSFFLYAFINMGMVSGILPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKSYKP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESILERHLVRAVMAISCIVVMSVIPP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LSYKRATPYLYASAVILLLGVIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMVAWIL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
AAEGGRPDIKKITICLLVTSVPAGLIFIQPDLDGAIFTVIYALFVLYFAGMSWKIIGSFI
HCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
GGVAITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKGWTNA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
TQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCKSSFNRLVSA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFALSFFLYAFINMGMVSGILPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKSYKP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]