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The map label for this gene is gpt [H]

Identifier: 157962254

GI number: 157962254

Start: 2973836

End: 2974291

Strand: Reverse

Name: gpt [H]

Synonym: Spea_2433

Alternate gene names: 157962254

Gene position: 2974291-2973836 (Counterclockwise)

Preceding gene: 157962255

Following gene: 157962253

Centisome position: 57.48

GC content: 44.3

Gene sequence:

>456_bases
ATGAGCAAGAAATTTCTGATCACTTGGGATCAAATGCAAGGTTATACCCGTGAGTTGGCTGAGCGCCTATTACCTGCAGA
GCAGTGGACAGGCATTATTGCGGTAAGCCGCGGCGGATTAGTACCTGCGGCTATTCTAGCTCGCGAATTAGGTATTCGTA
ATGTAGATACCATCTGTATCTCTAGCTACGATCATGATCACCAACGTGAAACTAAAATCATTAAGCAAGCACCAGGCGAC
GGTGAAGGCTTTATCGTTATTGATGATTTAGTTGATAGTGGTTCGACAGCAAAAATCGTTCGTGAAATTTACCCTAAGGC
TAAGTTTGTGACCGTTTGTGCAAAACCTGCCGGTAAGCCATTAGTCGATGATTATATCGTTGATATCGCACAAGACACAT
GGATTGAGCAGCCTTGGGATACAGGCGTGAGCTTTAGAGAGCCACTTTGTAAGTAA

Upstream 100 bases:

>100_bases
AATACATCACGAACATAAATTTGTATGGATCTGAATAACAAGCCAAAATGCCGCGCAATCTCTTTCCCCTAAAATAGCGA
ATACGCATAAAAGGTTGCAC

Downstream 100 bases:

>100_bases
TAAATTAGATTTAAATAAAACCGATGCCTAGCCTCGGTTTTTTTGTTTTCAGCCCTAAACCACTTACTTCAGTAGGTGGC
TCTTTTACTGTCAGCTCTAA

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MSKKFLITWDQMQGYTRELAERLLPAEQWTGIIAVSRGGLVPAAILARELGIRNVDTICISSYDHDHQRETKIIKQAPGD
GEGFIVIDDLVDSGSTAKIVREIYPKAKFVTVCAKPAGKPLVDDYIVDIAQDTWIEQPWDTGVSFREPLCK

Sequences:

>Translated_151_residues
MSKKFLITWDQMQGYTRELAERLLPAEQWTGIIAVSRGGLVPAAILARELGIRNVDTICISSYDHDHQRETKIIKQAPGD
GEGFIVIDDLVDSGSTAKIVREIYPKAKFVTVCAKPAGKPLVDDYIVDIAQDTWIEQPWDTGVSFREPLCK
>Mature_150_residues
SKKFLITWDQMQGYTRELAERLLPAEQWTGIIAVSRGGLVPAAILARELGIRNVDTICISSYDHDHQRETKIIKQAPGDG
EGFIVIDDLVDSGSTAKIVREIYPKAKFVTVCAKPAGKPLVDDYIVDIAQDTWIEQPWDTGVSFREPLCK

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=150, Percent_Identity=72, Blast_Score=237, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 16861; Mature: 16729

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKFLITWDQMQGYTRELAERLLPAEQWTGIIAVSRGGLVPAAILARELGIRNVDTICI
CCCCEEEEHHHHCCHHHHHHHHCCCHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEE
SSYDHDHQRETKIIKQAPGDGEGFIVIDDLVDSGSTAKIVREIYPKAKFVTVCAKPAGKP
ECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCC
LVDDYIVDIAQDTWIEQPWDTGVSFREPLCK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKKFLITWDQMQGYTRELAERLLPAEQWTGIIAVSRGGLVPAAILARELGIRNVDTICI
CCCEEEEHHHHCCHHHHHHHHCCCHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEE
SSYDHDHQRETKIIKQAPGDGEGFIVIDDLVDSGSTAKIVREIYPKAKFVTVCAKPAGKP
ECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCC
LVDDYIVDIAQDTWIEQPWDTGVSFREPLCK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA