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The map label for this gene is aspC [H]

Identifier: 157962049

GI number: 157962049

Start: 2699690

End: 2700883

Strand: Reverse

Name: aspC [H]

Synonym: Spea_2228

Alternate gene names: 157962049

Gene position: 2700883-2699690 (Counterclockwise)

Preceding gene: 157962050

Following gene: 157962047

Centisome position: 52.2

GC content: 43.47

Gene sequence:

>1194_bases
ATGATATTTTCCCAGGTTGAGCTGGCCCCTGCCGATCCAATTTTAGGCCTAACAGATGCATTTAAAGCAGATGTTCGCGA
CAACAAAGTGAACTTGGGCGTTGGCATATATAAAGATGAATCTGGCCAGACACCTATTTTAAAATCTGTAAAATTTGCAG
AAGAAAAATTATTAGCTACGGAAAAGAGTAAAAGCTATCTTGGTATGGAAGGTGTTGAAGCCTATAACCGCGTAGTTCAA
ACTCTGTTGTTTGGTACTGAGCATGCAGTCATTTCTCAATCTCGAGCATTAACAGCGCAGGCTCCAGGTGGAACAGGCTC
TTTACGCGTTGCTGCAGAATTCCTAGTTCGTCATACTAGCTCTAACAAGATTTGGATCAGTAATCCTACCTGGGCAAACC
ATAACAATATCTTTAGCACTGCAGGATTAGAAATTGCAGAGTACCGTTACTATAAAGCGGAAACTCATGGTCTAGATTTC
GATGCAATGCTAGCCGATCTACAGACTGCAGAAGCTGGCGATCTCGTATTGCTACACGGCTGTTGTCATAACCCAACGGG
TATCGACTTAGATAACGCACAATGGCAGCAAGTTGCTGATCTATGCTTAGCAAAATCGTTAGTGCCACTGTTCGATTTTG
CTTATCAAGGTTTTGGTTCAGGCGTTGAAGAAGACGCGCAAGGGCTTCGTATCGTTGCCAATACTGTTCCAGAATTGATT
GTTGCTAACTCATTCTCAAAGAATTTTGGCCTTTACAATGAACGTATCGGTGCGGTAACAGTTGTCGCTGCGAACGGTGA
TGAAGCAGTTAATGCATTTAGCCAAATCAAGAGCACCATTCGTGCTTCTTATTCAAATCCGCCTGCGCACGGTGCGTTAA
TTGTTAGCACCATTTTAGAAGATGAAACGTTAAAGCAGCTTTGGCATGACGAATTAAAAGAGATGCGTGAGCGTATCGCA
GAAATGCGTACACTGTTTGTTGAATCATTAAAAGCTGCGGGTGTAGAACAAGATTTTGATTTTATCTCTCGCCAAAACGG
CATGTTCAGTTTCTCAGGTCTAAATAAAGACCAAGTGAACCGCTTGCGAGATGAGTTTGCAGTCTACATCGTCGGCTCAG
GCCGCATCAGCGTAGCGGGCATGACCAAGACAAACATGCCTGTGATCTGTGCAGCTATCGCAAAAGTACTTTAA

Upstream 100 bases:

>100_bases
AAAATTTACTAATAGTCGTAAATCTCTCTTTCTCACTAATAGCATCAATGTTATAAATACACCCGATAACCCTACACTTC
TAATATTTAGGAAAGCCATA

Downstream 100 bases:

>100_bases
GCGTTACCTCTTAAAGTTCATGCGTTCAATAAAAAAGGACCTCTAAGGTCCTTTTTTATTGAACGCCCGATACCATTTAG
TGAACTAGGTGGATTCATTA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MIFSQVELAPADPILGLTDAFKADVRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLATEKSKSYLGMEGVEAYNRVVQ
TLLFGTEHAVISQSRALTAQAPGGTGSLRVAAEFLVRHTSSNKIWISNPTWANHNNIFSTAGLEIAEYRYYKAETHGLDF
DAMLADLQTAEAGDLVLLHGCCHNPTGIDLDNAQWQQVADLCLAKSLVPLFDFAYQGFGSGVEEDAQGLRIVANTVPELI
VANSFSKNFGLYNERIGAVTVVAANGDEAVNAFSQIKSTIRASYSNPPAHGALIVSTILEDETLKQLWHDELKEMRERIA
EMRTLFVESLKAAGVEQDFDFISRQNGMFSFSGLNKDQVNRLRDEFAVYIVGSGRISVAGMTKTNMPVICAAIAKVL

Sequences:

>Translated_397_residues
MIFSQVELAPADPILGLTDAFKADVRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLATEKSKSYLGMEGVEAYNRVVQ
TLLFGTEHAVISQSRALTAQAPGGTGSLRVAAEFLVRHTSSNKIWISNPTWANHNNIFSTAGLEIAEYRYYKAETHGLDF
DAMLADLQTAEAGDLVLLHGCCHNPTGIDLDNAQWQQVADLCLAKSLVPLFDFAYQGFGSGVEEDAQGLRIVANTVPELI
VANSFSKNFGLYNERIGAVTVVAANGDEAVNAFSQIKSTIRASYSNPPAHGALIVSTILEDETLKQLWHDELKEMRERIA
EMRTLFVESLKAAGVEQDFDFISRQNGMFSFSGLNKDQVNRLRDEFAVYIVGSGRISVAGMTKTNMPVICAAIAKVL
>Mature_397_residues
MIFSQVELAPADPILGLTDAFKADVRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLATEKSKSYLGMEGVEAYNRVVQ
TLLFGTEHAVISQSRALTAQAPGGTGSLRVAAEFLVRHTSSNKIWISNPTWANHNNIFSTAGLEIAEYRYYKAETHGLDF
DAMLADLQTAEAGDLVLLHGCCHNPTGIDLDNAQWQQVADLCLAKSLVPLFDFAYQGFGSGVEEDAQGLRIVANTVPELI
VANSFSKNFGLYNERIGAVTVVAANGDEAVNAFSQIKSTIRASYSNPPAHGALIVSTILEDETLKQLWHDELKEMRERIA
EMRTLFVESLKAAGVEQDFDFISRQNGMFSFSGLNKDQVNRLRDEFAVYIVGSGRISVAGMTKTNMPVICAAIAKVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=41.1616161616162, Blast_Score=322, Evalue=3e-88,
Organism=Homo sapiens, GI4504067, Length=401, Percent_Identity=39.9002493765586, Blast_Score=293, Evalue=1e-79,
Organism=Homo sapiens, GI117414139, Length=382, Percent_Identity=26.1780104712042, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=58.8383838383838, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=44.8362720403023, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=41.5189873417722, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=42.0253164556962, Blast_Score=339, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17569539, Length=394, Percent_Identity=35.7868020304569, Blast_Score=268, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=40.7582938388626, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=28.9405684754522, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=35.361216730038, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=38.423645320197, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6322743, Length=432, Percent_Identity=34.4907407407407, Blast_Score=241, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24580970, Length=397, Percent_Identity=40.8060453400504, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24580972, Length=397, Percent_Identity=40.8060453400504, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI19922362, Length=395, Percent_Identity=42.2784810126582, Blast_Score=317, Evalue=9e-87,
Organism=Drosophila melanogaster, GI24654046, Length=395, Percent_Identity=42.2784810126582, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI19920542, Length=392, Percent_Identity=40.5612244897959, Blast_Score=315, Evalue=2e-86,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43335; Mature: 43335

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSQVELAPADPILGLTDAFKADVRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLAT
CCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
EKSKSYLGMEGVEAYNRVVQTLLFGTEHAVISQSRALTAQAPGGTGSLRVAAEFLVRHTS
HCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCC
SNKIWISNPTWANHNNIFSTAGLEIAEYRYYKAETHGLDFDAMLADLQTAEAGDLVLLHG
CCEEEECCCCCCCCCCEEECCCCCHHHHEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEC
CCHNPTGIDLDNAQWQQVADLCLAKSLVPLFDFAYQGFGSGVEEDAQGLRIVANTVPELI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEHHHHHHHHH
VANSFSKNFGLYNERIGAVTVVAANGDEAVNAFSQIKSTIRASYSNPPAHGALIVSTILE
HHCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
DETLKQLWHDELKEMRERIAEMRTLFVESLKAAGVEQDFDFISRQNGMFSFSGLNKDQVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCHHHHH
RLRDEFAVYIVGSGRISVAGMTKTNMPVICAAIAKVL
HHHHCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHC
>Mature Secondary Structure
MIFSQVELAPADPILGLTDAFKADVRDNKVNLGVGIYKDESGQTPILKSVKFAEEKLLAT
CCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
EKSKSYLGMEGVEAYNRVVQTLLFGTEHAVISQSRALTAQAPGGTGSLRVAAEFLVRHTS
HCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCC
SNKIWISNPTWANHNNIFSTAGLEIAEYRYYKAETHGLDFDAMLADLQTAEAGDLVLLHG
CCEEEECCCCCCCCCCEEECCCCCHHHHEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEC
CCHNPTGIDLDNAQWQQVADLCLAKSLVPLFDFAYQGFGSGVEEDAQGLRIVANTVPELI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEHHHHHHHHH
VANSFSKNFGLYNERIGAVTVVAANGDEAVNAFSQIKSTIRASYSNPPAHGALIVSTILE
HHCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
DETLKQLWHDELKEMRERIAEMRTLFVESLKAAGVEQDFDFISRQNGMFSFSGLNKDQVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCHHHHH
RLRDEFAVYIVGSGRISVAGMTKTNMPVICAAIAKVL
HHHHCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]