| Definition | Shewanella pealeana ATCC 700345 chromosome, complete genome. |
|---|---|
| Accession | NC_009901 |
| Length | 5,174,581 |
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The map label for this gene is fabG [C]
Identifier: 157961958
GI number: 157961958
Start: 2589023
End: 2589793
Strand: Direct
Name: fabG [C]
Synonym: Spea_2137
Alternate gene names: 157961958
Gene position: 2589023-2589793 (Clockwise)
Preceding gene: 157961956
Following gene: 157961959
Centisome position: 50.03
GC content: 46.69
Gene sequence:
>771_bases ATGCAGATTGATTACCAGAATAAAGTGGTATTGGTGACAGGTGGCACTAAAGGTATTGGAGCAGGCATTGCTACGGAGTT TCTTGCAGCTGGAGCCAAAGTAATCGTTTGCGGTCGCAGTGAGCCGCAAACACTACCAAATTCCGGTAACAACACTGCGC AGTTTATTTATGCGGACCTTAAAAAACATGACGATATTGAAACCTTGTTTAGCACGATTGCTAAACAATATCCCCGTCTT GATGTGGTGATCAATAACGCCGGAGGAAGCCCTTTTGCGTTAGCCGACAAAGCCTCACCACGATTCCATGAGAGCATTCT TCGCCTAAATCTTATTGCGCCTTTAAATGTCGCTCAACAAGCGAACGCACTAATGCAAGAACAAGACTCGGGGGGGGCAA TTGTGTTTATAGGCAGTATTAGTGCGCTTAGAGCCTCTCCAGGGACCGCAGCCTATGGAGCAGCAAAAGCGGCGGTATTG TCATTAGTACAATCTCTTGCCGTTGAATGGGCACCAAAAGTTAAGGTAATGGCCGTCAGCCCGGGTCTAGTAAAAACCGA GCAATCGCAGCTTCATTATGGTGATGATGAGGGGATAGCTGCGGTCGCTAAAACGATACCTGCAGGTCGATTAGCCGATC CGGCTGACATAGCTAAGGCTTGTTTATTTCTCGCATCAGAAAACGGTTTTTATGCCAGTGGTTGCAACTTATTACTTAAC GGAGGCGGCGAAATGCCTGCGTTTTTAATGGCTTCTCAAACTACTCAATAA
Upstream 100 bases:
>100_bases GAAGCTAACTTTGCCTAGCTAATGATATTTATATAAGCCTAAGAAAAACGGCGAGTTAACTTCAATTTTGGCCGTTACAA ATATGACTAAGGGTAAAGTT
Downstream 100 bases:
>100_bases TTAATAGCAGTAACAAAATGGTTTGTATGAGCTTTATAACGAGCGGGTACCAGCTTGTTTAACAACATTATTTTAAGCAT TGAGTGCAGAGATACTCAAG
Product: short chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MQIDYQNKVVLVTGGTKGIGAGIATEFLAAGAKVIVCGRSEPQTLPNSGNNTAQFIYADLKKHDDIETLFSTIAKQYPRL DVVINNAGGSPFALADKASPRFHESILRLNLIAPLNVAQQANALMQEQDSGGAIVFIGSISALRASPGTAAYGAAKAAVL SLVQSLAVEWAPKVKVMAVSPGLVKTEQSQLHYGDDEGIAAVAKTIPAGRLADPADIAKACLFLASENGFYASGCNLLLN GGGEMPAFLMASQTTQ
Sequences:
>Translated_256_residues MQIDYQNKVVLVTGGTKGIGAGIATEFLAAGAKVIVCGRSEPQTLPNSGNNTAQFIYADLKKHDDIETLFSTIAKQYPRL DVVINNAGGSPFALADKASPRFHESILRLNLIAPLNVAQQANALMQEQDSGGAIVFIGSISALRASPGTAAYGAAKAAVL SLVQSLAVEWAPKVKVMAVSPGLVKTEQSQLHYGDDEGIAAVAKTIPAGRLADPADIAKACLFLASENGFYASGCNLLLN GGGEMPAFLMASQTTQ >Mature_256_residues MQIDYQNKVVLVTGGTKGIGAGIATEFLAAGAKVIVCGRSEPQTLPNSGNNTAQFIYADLKKHDDIETLFSTIAKQYPRL DVVINNAGGSPFALADKASPRFHESILRLNLIAPLNVAQQANALMQEQDSGGAIVFIGSISALRASPGTAAYGAAKAAVL SLVQSLAVEWAPKVKVMAVSPGLVKTEQSQLHYGDDEGIAAVAKTIPAGRLADPADIAKACLFLASENGFYASGCNLLLN GGGEMPAFLMASQTTQ
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=32.6530612244898, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI59889578, Length=241, Percent_Identity=31.5352697095436, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=30.1960784313725, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=28.4518828451883, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=26.1904761904762, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=27.9835390946502, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=27.2, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI109715829, Length=237, Percent_Identity=29.535864978903, Blast_Score=84, Evalue=8e-17, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=29.5336787564767, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI126723191, Length=175, Percent_Identity=32, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=26.7441860465116, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4758504, Length=234, Percent_Identity=28.6324786324786, Blast_Score=72, Evalue=6e-13, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=30.7377049180328, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=29.045643153527, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=31.25, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=31.3953488372093, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1787526, Length=238, Percent_Identity=27.3109243697479, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=28.1632653061224, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787820, Length=226, Percent_Identity=29.2035398230088, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=27.4193548387097, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=26.4227642276423, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=23.9669421487603, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=24.8, Blast_Score=67, Evalue=9e-13, Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=29.718875502008, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=28.8065843621399, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562904, Length=275, Percent_Identity=31.2727272727273, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=28.1124497991968, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.1632653061224, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=31.3432835820896, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=29.2134831460674, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=29.5019157088123, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=26.5060240963855, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=27.8688524590164, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=28.996282527881, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=28.8065843621399, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=28.3088235294118, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=26.7657992565056, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=26.9961977186312, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI71997402, Length=195, Percent_Identity=29.2307692307692, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=27.6752767527675, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=26.9372693726937, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17561272, Length=232, Percent_Identity=26.7241379310345, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=27.3764258555133, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17560150, Length=277, Percent_Identity=26.3537906137184, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17570069, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=29.0441176470588, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=25.968992248062, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17562990, Length=278, Percent_Identity=25.1798561151079, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=25.7575757575758, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17555612, Length=220, Percent_Identity=27.7272727272727, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=25.9109311740891, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=229, Percent_Identity=31.0043668122271, Blast_Score=79, Evalue=7e-16, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=26.8, Blast_Score=77, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6322067, Length=186, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.1204819277108, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=28.1124497991968, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=29.4820717131474, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=29.7959183673469, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=26.8292682926829, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=31.3253012048193, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=29.8039215686275, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24641232, Length=200, Percent_Identity=29.5, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=27.8008298755187, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI116007236, Length=238, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI281364494, Length=241, Percent_Identity=25.3112033195021, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007234, Length=206, Percent_Identity=24.7572815533981, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=29.0155440414508, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI28571387, Length=198, Percent_Identity=25.2525252525253, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24580925, Length=205, Percent_Identity=26.3414634146341, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 26605; Mature: 26605
Theoretical pI: Translated: 6.26; Mature: 6.26
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQIDYQNKVVLVTGGTKGIGAGIATEFLAAGAKVIVCGRSEPQTLPNSGNNTAQFIYADL CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEEEEEC KKHDDIETLFSTIAKQYPRLDVVINNAGGSPFALADKASPRFHESILRLNLIAPLNVAQQ CCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCHHHHHHHHHEEECCCCHHHH ANALMQEQDSGGAIVFIGSISALRASPGTAAYGAAKAAVLSLVQSLAVEWAPKVKVMAVS HHHHHHHCCCCCEEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC PGLVKTEQSQLHYGDDEGIAAVAKTIPAGRLADPADIAKACLFLASENGFYASGCNLLLN CCCEECCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHEECCCCEEECCCEEEEE GGGEMPAFLMASQTTQ CCCCCCEEEEECCCCC >Mature Secondary Structure MQIDYQNKVVLVTGGTKGIGAGIATEFLAAGAKVIVCGRSEPQTLPNSGNNTAQFIYADL CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEEEEEEC KKHDDIETLFSTIAKQYPRLDVVINNAGGSPFALADKASPRFHESILRLNLIAPLNVAQQ CCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCHHHHHHHHHEEECCCCHHHH ANALMQEQDSGGAIVFIGSISALRASPGTAAYGAAKAAVLSLVQSLAVEWAPKVKVMAVS HHHHHHHCCCCCEEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC PGLVKTEQSQLHYGDDEGIAAVAKTIPAGRLADPADIAKACLFLASENGFYASGCNLLLN CCCEECCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHEECCCCEEECCCEEEEE GGGEMPAFLMASQTTQ CCCCCCEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8796346; 9163424 [H]