Click here to switch to the map view.

The map label for this gene is dgoT [H]

Identifier: 157961943

GI number: 157961943

Start: 2567365

End: 2568750

Strand: Reverse

Name: dgoT [H]

Synonym: Spea_2122

Alternate gene names: 157961943

Gene position: 2568750-2567365 (Counterclockwise)

Preceding gene: 157961948

Following gene: 157961942

Centisome position: 49.64

GC content: 45.31

Gene sequence:

>1386_bases
ATGCAGCCTATTTTACCCTCAGTGACATGGCGTACACATAGCACGCTTGTGTTGTTAGCACTGGTTTACGTCTTTTCATT
TATTGATAGGAATGTCATTGCCATCGTTCTGGAGCCAATAAAACAAGAGTTTGGTGCATCAGATACGTTAATGGGTTTCT
TAAGTGGTCTTGCATTTGCCATTCTATATGCAGGGTTAAGCTTACCTCTAAGCCGTTTAGCTGACAGAGGCGGAAATAGA
CGTAACATTATTGCGGTATGCTGCGGGCTATGGAGCATTGCAACAATGGCCTGTGGTATGGCGCAGCACTTCTGGCAATT
GATGATAGCCAGAATGACGGTTGCAGTGGGTGAGGCTGGCGGTATAGCGCCGTCAATATCTATGGTGTCAGATCTTTACC
CGCCTCACCGTCGTTCATTGGCCATTAGCGTATTAATGATTGGCCCTCATCTTGGGTTACTAGCAGCAATGGTTGCTGGC
GGGTGGATTGCGCAGGAATATGGGTGGCGTTCTGTGTTCTTATTCTTTGGTGCCCCCGGTATTTTGCTTGCGCTACTGCT
ATTTTGCTTTACCAAAGATCCTGGGCATGGTGTTTACGACAAAAATACCACGCTCAATAATGAAAAAAATAAGCAAGAGT
CCTTTTTCAAACAGTTAAAAGGAATAATGAAAGTAAAAGGATTTATTTGGATCGCTATGGGCTGCGCACTCGCAGGCATG
GCTGGTTATGGTTACGGTATATGGGTACCGACGTTCATGGTACGTAACTACGATATGTCTTTAGCTCATGCTGGTATTAG
CTTTGGATTAGCCGGCGGTATTTTTGCTGCTATCGGTACTATATTCAGTGGCGTTTTTTGTGACAAGTTGTCAAAGCGCG
ACTCTCGTTGGCAAATTGGCCTGCCCATCATAGGTATTTTGATCAGCCTGCCTATGGGAGTGGCCTTTATGTTATGGCCA
GCTGACGCCTTTTGGATGGTGGGAGAGATCAAAATCCCCCACGCTATTGTTTTTGCAGCCCTGTTTAGTTTTTTTAATTG
CTGGTGGCCGAGTTTATCTTATGCAGCTATCAGTCATTTAATGACCAGCAGCCAACGTGCAACTGGCGCTGCGTCACTAA
ACCTATTCTTAACACTTTTCGGAGCAGGCCTTGGCCCGTTGCTAACAGGTACATTAAGTGACGTGTTTGGAGAAATATTC
GCAGGTGAAGGCCTCAAATATGCGCTCGTGGCCACTATGATGCTGCTGCTCGTTTCTGCATGGTTTTACTATAAAGGACT
ATCTCCTTATCAAACTCGAATGAAACAGTTGAATAACGATGAGGTTGAATCAATAGATAACTCCGTGCCACCGACTACCG
TTAACGATCCACTTCCAAGTACATAG

Upstream 100 bases:

>100_bases
GAATCTATTCCACGAGATAGCAACACGTCCAAAAGGACGATGTCTGGATTTTTCGCTAGGTTACCTTTGAGAAACTGCGA
TCTTAATTATGGAGCTCATT

Downstream 100 bases:

>100_bases
ATAATTAAAACGATAATTAAAACGATAATTATACCGGCACGGTTAGGTAATAGTGCCGGAATGAATAATATAAAAAACAT
AATTAGCAAGGAGTTACGCA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQPILPSVTWRTHSTLVLLALVYVFSFIDRNVIAIVLEPIKQEFGASDTLMGFLSGLAFAILYAGLSLPLSRLADRGGNR
RNIIAVCCGLWSIATMACGMAQHFWQLMIARMTVAVGEAGGIAPSISMVSDLYPPHRRSLAISVLMIGPHLGLLAAMVAG
GWIAQEYGWRSVFLFFGAPGILLALLLFCFTKDPGHGVYDKNTTLNNEKNKQESFFKQLKGIMKVKGFIWIAMGCALAGM
AGYGYGIWVPTFMVRNYDMSLAHAGISFGLAGGIFAAIGTIFSGVFCDKLSKRDSRWQIGLPIIGILISLPMGVAFMLWP
ADAFWMVGEIKIPHAIVFAALFSFFNCWWPSLSYAAISHLMTSSQRATGAASLNLFLTLFGAGLGPLLTGTLSDVFGEIF
AGEGLKYALVATMMLLLVSAWFYYKGLSPYQTRMKQLNNDEVESIDNSVPPTTVNDPLPST

Sequences:

>Translated_461_residues
MQPILPSVTWRTHSTLVLLALVYVFSFIDRNVIAIVLEPIKQEFGASDTLMGFLSGLAFAILYAGLSLPLSRLADRGGNR
RNIIAVCCGLWSIATMACGMAQHFWQLMIARMTVAVGEAGGIAPSISMVSDLYPPHRRSLAISVLMIGPHLGLLAAMVAG
GWIAQEYGWRSVFLFFGAPGILLALLLFCFTKDPGHGVYDKNTTLNNEKNKQESFFKQLKGIMKVKGFIWIAMGCALAGM
AGYGYGIWVPTFMVRNYDMSLAHAGISFGLAGGIFAAIGTIFSGVFCDKLSKRDSRWQIGLPIIGILISLPMGVAFMLWP
ADAFWMVGEIKIPHAIVFAALFSFFNCWWPSLSYAAISHLMTSSQRATGAASLNLFLTLFGAGLGPLLTGTLSDVFGEIF
AGEGLKYALVATMMLLLVSAWFYYKGLSPYQTRMKQLNNDEVESIDNSVPPTTVNDPLPST
>Mature_461_residues
MQPILPSVTWRTHSTLVLLALVYVFSFIDRNVIAIVLEPIKQEFGASDTLMGFLSGLAFAILYAGLSLPLSRLADRGGNR
RNIIAVCCGLWSIATMACGMAQHFWQLMIARMTVAVGEAGGIAPSISMVSDLYPPHRRSLAISVLMIGPHLGLLAAMVAG
GWIAQEYGWRSVFLFFGAPGILLALLLFCFTKDPGHGVYDKNTTLNNEKNKQESFFKQLKGIMKVKGFIWIAMGCALAGM
AGYGYGIWVPTFMVRNYDMSLAHAGISFGLAGGIFAAIGTIFSGVFCDKLSKRDSRWQIGLPIIGILISLPMGVAFMLWP
ADAFWMVGEIKIPHAIVFAALFSFFNCWWPSLSYAAISHLMTSSQRATGAASLNLFLTLFGAGLGPLLTGTLSDVFGEIF
AGEGLKYALVATMMLLLVSAWFYYKGLSPYQTRMKQLNNDEVESIDNSVPPTTVNDPLPST

Specific function: Intake of galactonate into the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=482, Percent_Identity=22.6141078838174, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI215490096, Length=403, Percent_Identity=22.0843672456576, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI14042968, Length=403, Percent_Identity=22.0843672456576, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082320, Length=299, Percent_Identity=25.0836120401338, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI2367379, Length=392, Percent_Identity=21.9387755102041, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789152, Length=334, Percent_Identity=24.8502994011976, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87082231, Length=183, Percent_Identity=31.6939890710383, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539092, Length=499, Percent_Identity=22.0440881763527, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71992409, Length=491, Percent_Identity=22.1995926680244, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24654037, Length=390, Percent_Identity=24.3589743589744, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24654041, Length=390, Percent_Identity=24.3589743589744, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640209, Length=158, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50127; Mature: 50127

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPILPSVTWRTHSTLVLLALVYVFSFIDRNVIAIVLEPIKQEFGASDTLMGFLSGLAFA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ILYAGLSLPLSRLADRGGNRRNIIAVCCGLWSIATMACGMAQHFWQLMIARMTVAVGEAG
HHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIAPSISMVSDLYPPHRRSLAISVLMIGPHLGLLAAMVAGGWIAQEYGWRSVFLFFGAPG
CCCCHHHHHHHCCCCCCHHHEEEEEEECCHHHHHHHHHHCCHHHHHCCCCEEEHHHCCHH
ILLALLLFCFTKDPGHGVYDKNTTLNNEKNKQESFFKQLKGIMKVKGFIWIAMGCALAGM
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGYGYGIWVPTFMVRNYDMSLAHAGISFGLAGGIFAAIGTIFSGVFCDKLSKRDSRWQIG
CCCCCHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
LPIIGILISLPMGVAFMLWPADAFWMVGEIKIPHAIVFAALFSFFNCWWPSLSYAAISHL
HHHHHHHHHHHHHHEEHEECCCHHEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MTSSQRATGAASLNLFLTLFGAGLGPLLTGTLSDVFGEIFAGEGLKYALVATMMLLLVSA
HHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WFYYKGLSPYQTRMKQLNNDEVESIDNSVPPTTVNDPLPST
HHHHCCCCHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPILPSVTWRTHSTLVLLALVYVFSFIDRNVIAIVLEPIKQEFGASDTLMGFLSGLAFA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ILYAGLSLPLSRLADRGGNRRNIIAVCCGLWSIATMACGMAQHFWQLMIARMTVAVGEAG
HHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIAPSISMVSDLYPPHRRSLAISVLMIGPHLGLLAAMVAGGWIAQEYGWRSVFLFFGAPG
CCCCHHHHHHHCCCCCCHHHEEEEEEECCHHHHHHHHHHCCHHHHHCCCCEEEHHHCCHH
ILLALLLFCFTKDPGHGVYDKNTTLNNEKNKQESFFKQLKGIMKVKGFIWIAMGCALAGM
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGYGYGIWVPTFMVRNYDMSLAHAGISFGLAGGIFAAIGTIFSGVFCDKLSKRDSRWQIG
CCCCCHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
LPIIGILISLPMGVAFMLWPADAFWMVGEIKIPHAIVFAALFSFFNCWWPSLSYAAISHL
HHHHHHHHHHHHHHEEHEECCCHHEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MTSSQRATGAASLNLFLTLFGAGLGPLLTGTLSDVFGEIFAGEGLKYALVATMMLLLVSA
HHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WFYYKGLSPYQTRMKQLNNDEVESIDNSVPPTTVNDPLPST
HHHHCCCCHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]