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The map label for this gene is ydhC [H]

Identifier: 157961934

GI number: 157961934

Start: 2556685

End: 2557929

Strand: Direct

Name: ydhC [H]

Synonym: Spea_2113

Alternate gene names: 157961934

Gene position: 2556685-2557929 (Clockwise)

Preceding gene: 157961927

Following gene: 157961941

Centisome position: 49.41

GC content: 40.48

Gene sequence:

>1245_bases
ATGAACTCACTAACAAGTGTAAAATACTATATTTTTCTAGCATATCTAGCGGTATTGAGCATGTTAGGCTTTATTGCCAC
TGACATGTACTTGCCTGCATTCAAAGCAATTGAAGACACAATGGCAACATCGCCATCACAAGTCGCAATGTCTTTGACAT
TCTTTTTAGCCGGCTTAGCGCTAGGTCAGTTACTTTATGGTCCTTTAGTTGAGCGTTTTGGTAAACGTAATTCACTGATC
TTAGGTCTAGTATTGTTTGCTGCTGCAAGCTTCTCGATATCCGTTAGTGATTCAATTTTAGTATTTAATATTTCGCGTTT
TATACAAGCATTAGGTGCATGTTCTGCCGGCGTTATTTGGCAGGCGATTGTTATTGAAAAATACGATGCAGCAAAAGCAC
AGGGCGTATTTTCTAATATTATGCCGTTAGTGGCCTTGTCACCAGCACTTGCTCCAATCTTAGGTGCGTTTATCTTACAA
TCGTTAGGTTGGCAGAGCATTTTCATTACATTGACCGGTATGGCTGCTGTAATGATTCTTTTGACAGTTTGGTTTGTGCC
TGCAGAAACCAAAGCAATAAGCCATGAAAAGAAAGAGATCAGCTATTTAACAATCCTTAAGAACACTAAATACCTAGGCA
ACGTGGTTATTTTTGGTGCTTGTTCTGGTGCGTTTTTCTCATACCTAACACTGTGGCCAGTAGTGATGGAGCAGCATGGA
TTCGATGCTACAGCAATTGGGCTGAGCTTTATTCCGCAAACTATTACCTTTATTTTGGGTGGCTATGCGAGTAAAACGCT
TATTCGTAAAATCGGTTCAGAGAAAACCTTAAAGCTATTACTATCTGTATTTGGCACGTGTGCTATGTCTATTGCAGTAG
TGACAATCTTACTGCAAGGACTATCAATTTATCCATTGCTAGCTATATTCTCTGTACTTGCAGCGTGTAGTGGTGGTATT
TACCCAATTGTTGTAAACGGTGCATTGCAGGAATTCTCTGATAACGCAGCTAAAGCGGCGGGTTTACAGAACTTCCTACA
GATCAGCTTATCATTTGGTGCTTCAAGCCTTGTAGCTATGTGGGCGACAAGTGGTGAAGTTGCGATAGGTTGGGGGATTA
TGATCTGCTCATTCATCGTATTTATTGGCTTCAAACTACGTAACTATAAAAATTGGAATGAGGTTAGCGAAGAGATCGTA
ATGCCAGATCCTGCGCGCATTGCAATCAATCAGGATGAGAAATAA

Upstream 100 bases:

>100_bases
ATTTTTTTTGATAGCTAATGTGAAAAATAAACGTTTCACAGCACATTAGCAAGTGTTTACACTGCGCGACTTTAATAAAT
CCAGATCAGAATTTCGAATT

Downstream 100 bases:

>100_bases
GCAAACTGATTCGTTCTTAATCAAAGTGATAATTTGTTAAAATTATCACTTTACAAGAACTACAGAGCGCTATATTATCC
GCAGCGTTCGGAGAGATGGC

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MNSLTSVKYYIFLAYLAVLSMLGFIATDMYLPAFKAIEDTMATSPSQVAMSLTFFLAGLALGQLLYGPLVERFGKRNSLI
LGLVLFAAASFSISVSDSILVFNISRFIQALGACSAGVIWQAIVIEKYDAAKAQGVFSNIMPLVALSPALAPILGAFILQ
SLGWQSIFITLTGMAAVMILLTVWFVPAETKAISHEKKEISYLTILKNTKYLGNVVIFGACSGAFFSYLTLWPVVMEQHG
FDATAIGLSFIPQTITFILGGYASKTLIRKIGSEKTLKLLLSVFGTCAMSIAVVTILLQGLSIYPLLAIFSVLAACSGGI
YPIVVNGALQEFSDNAAKAAGLQNFLQISLSFGASSLVAMWATSGEVAIGWGIMICSFIVFIGFKLRNYKNWNEVSEEIV
MPDPARIAINQDEK

Sequences:

>Translated_414_residues
MNSLTSVKYYIFLAYLAVLSMLGFIATDMYLPAFKAIEDTMATSPSQVAMSLTFFLAGLALGQLLYGPLVERFGKRNSLI
LGLVLFAAASFSISVSDSILVFNISRFIQALGACSAGVIWQAIVIEKYDAAKAQGVFSNIMPLVALSPALAPILGAFILQ
SLGWQSIFITLTGMAAVMILLTVWFVPAETKAISHEKKEISYLTILKNTKYLGNVVIFGACSGAFFSYLTLWPVVMEQHG
FDATAIGLSFIPQTITFILGGYASKTLIRKIGSEKTLKLLLSVFGTCAMSIAVVTILLQGLSIYPLLAIFSVLAACSGGI
YPIVVNGALQEFSDNAAKAAGLQNFLQISLSFGASSLVAMWATSGEVAIGWGIMICSFIVFIGFKLRNYKNWNEVSEEIV
MPDPARIAINQDEK
>Mature_414_residues
MNSLTSVKYYIFLAYLAVLSMLGFIATDMYLPAFKAIEDTMATSPSQVAMSLTFFLAGLALGQLLYGPLVERFGKRNSLI
LGLVLFAAASFSISVSDSILVFNISRFIQALGACSAGVIWQAIVIEKYDAAKAQGVFSNIMPLVALSPALAPILGAFILQ
SLGWQSIFITLTGMAAVMILLTVWFVPAETKAISHEKKEISYLTILKNTKYLGNVVIFGACSGAFFSYLTLWPVVMEQHG
FDATAIGLSFIPQTITFILGGYASKTLIRKIGSEKTLKLLLSVFGTCAMSIAVVTILLQGLSIYPLLAIFSVLAACSGGI
YPIVVNGALQEFSDNAAKAAGLQNFLQISLSFGASSLVAMWATSGEVAIGWGIMICSFIVFIGFKLRNYKNWNEVSEEIV
MPDPARIAINQDEK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=353, Percent_Identity=42.7762039660057, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI1788509, Length=368, Percent_Identity=23.6413043478261, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790146, Length=255, Percent_Identity=29.8039215686275, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787065, Length=271, Percent_Identity=25.830258302583, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44595; Mature: 44595

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLTSVKYYIFLAYLAVLSMLGFIATDMYLPAFKAIEDTMATSPSQVAMSLTFFLAGLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGQLLYGPLVERFGKRNSLILGLVLFAAASFSISVSDSILVFNISRFIQALGACSAGVIW
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCEEEEEHHHHHHHHHCCCHHHHH
QAIVIEKYDAAKAQGVFSNIMPLVALSPALAPILGAFILQSLGWQSIFITLTGMAAVMIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LTVWFVPAETKAISHEKKEISYLTILKNTKYLGNVVIFGACSGAFFSYLTLWPVVMEQHG
HHHHHCCCCHHHHHHHHHHHHHHEEECCCCHHCCEEEEECCHHHHHHHHHHHHHHHHHCC
FDATAIGLSFIPQTITFILGGYASKTLIRKIGSEKTLKLLLSVFGTCAMSIAVVTILLQG
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LSIYPLLAIFSVLAACSGGIYPIVVNGALQEFSDNAAKAAGLQNFLQISLSFGASSLVAM
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHH
WATSGEVAIGWGIMICSFIVFIGFKLRNYKNWNEVSEEIVMPDPARIAINQDEK
HCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEECCCCCC
>Mature Secondary Structure
MNSLTSVKYYIFLAYLAVLSMLGFIATDMYLPAFKAIEDTMATSPSQVAMSLTFFLAGLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGQLLYGPLVERFGKRNSLILGLVLFAAASFSISVSDSILVFNISRFIQALGACSAGVIW
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCEEEEEHHHHHHHHHCCCHHHHH
QAIVIEKYDAAKAQGVFSNIMPLVALSPALAPILGAFILQSLGWQSIFITLTGMAAVMIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LTVWFVPAETKAISHEKKEISYLTILKNTKYLGNVVIFGACSGAFFSYLTLWPVVMEQHG
HHHHHCCCCHHHHHHHHHHHHHHEEECCCCHHCCEEEEECCHHHHHHHHHHHHHHHHHCC
FDATAIGLSFIPQTITFILGGYASKTLIRKIGSEKTLKLLLSVFGTCAMSIAVVTILLQG
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
LSIYPLLAIFSVLAACSGGIYPIVVNGALQEFSDNAAKAAGLQNFLQISLSFGASSLVAM
HHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHH
WATSGEVAIGWGIMICSFIVFIGFKLRNYKNWNEVSEEIVMPDPARIAINQDEK
HCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]