BacMap

Definition	Shewanella pealeana ATCC 700345 chromosome, complete genome.
Accession	NC_009901
Length	5,174,581

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The map label for this gene is fadH [H]

Identifier: 157961899

GI number: 157961899

Start: 2517614

End: 2518420

Strand: Direct

Name: fadH [H]

Synonym: Spea_2078

Alternate gene names: 157961899

Gene position: 2517614-2518420 (Clockwise)

Preceding gene: 157961898

Following gene: 157961900

Centisome position: 48.65

GC content: 46.72

Gene sequence:

>807_bases
ATGTTTAGCTATCAAGGAAAGAATGTTGTCGTTGTAGGTGGTACTAGCGGGATTAATCTTGCTATTGCCGTTCACTTCTC
TCAAGCCGGAGCGAATGTTGCTGTGGCGAGCCGCTCCGTCGAAAAAGTAGATGCCGCTGTAGAGTTATTAAAACAAGCAA
ACCCTAATGGAGAACACTTAGGTGTTTGCTTTGATGTCAGGGATCTTGAGGCCTTATCAAAGGGCTTTGCTACTATTAGT
GATGCCTTCTCAACTATCGATGTTTTAGTGAGTGGCGCCGCCGGTAATTTTCCGTCAACTGCTGAAAAGCTTTCCGAAAA
TGGTTTTAAGTCGGTAATGGATATCGATCTCTTAGGCAGTTTTCAGGTGCTTAAGCAGGCTTATCCATTAATGAGTGACA
CTGGTGGAGCGATTATACAGATCTCTGCACCACAGGCGTTTGTACCTATGCCTATGCAAGTTCATGTGTGCGCTGCTAAA
GCGGGCGTTGATATGTTAACTAAAACATTAGCAATAGAATGGGGACGCAAAGGGATCAGGATAAATTCAATTGTCCCAGG
TCCTATAGCGGGAACCGAAGGCTTTAATCGGTTAGCCCCATCAGAAGAGCTGCAGGCTCACGTTGCGCAAGGCGTTCCAT
TAAAACGTAATGGGCGTTGTGAAGACATTGCCAACGCGGCCCTATTTCTCGCTTCAGATATGGCCTCGTATATCACAGGC
ACTGTGTTGCCAGTTGATGGTGGTTGGTCATTAGGTGGGGCTGGTTCTGCAATCGCCGAGATCGGCCAATTAGCTAGACG
CAACTAA

Upstream 100 bases:

>100_bases
GGCGATACACCAAACGATTGCTTAATTGAGTATTGCCTAGTAGGTTAGATTTATATTCGCATGACTGCTTAAAAAATCTA
ATTCTAAGGGAGAAGTTACA

Downstream 100 bases:

>100_bases
GTAAGATACGAATAAAAGTTCAGTACAATTAGAGTAATCGTTAATTTAGAGATTTTTAGATATGGCAAACCCATTTCAAG
AGCAGCTTCTTAAAGCTGGT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MFSYQGKNVVVVGGTSGINLAIAVHFSQAGANVAVASRSVEKVDAAVELLKQANPNGEHLGVCFDVRDLEALSKGFATIS
DAFSTIDVLVSGAAGNFPSTAEKLSENGFKSVMDIDLLGSFQVLKQAYPLMSDTGGAIIQISAPQAFVPMPMQVHVCAAK
AGVDMLTKTLAIEWGRKGIRINSIVPGPIAGTEGFNRLAPSEELQAHVAQGVPLKRNGRCEDIANAALFLASDMASYITG
TVLPVDGGWSLGGAGSAIAEIGQLARRN

Sequences:

>Translated_268_residues
MFSYQGKNVVVVGGTSGINLAIAVHFSQAGANVAVASRSVEKVDAAVELLKQANPNGEHLGVCFDVRDLEALSKGFATIS
DAFSTIDVLVSGAAGNFPSTAEKLSENGFKSVMDIDLLGSFQVLKQAYPLMSDTGGAIIQISAPQAFVPMPMQVHVCAAK
AGVDMLTKTLAIEWGRKGIRINSIVPGPIAGTEGFNRLAPSEELQAHVAQGVPLKRNGRCEDIANAALFLASDMASYITG
TVLPVDGGWSLGGAGSAIAEIGQLARRN
>Mature_268_residues
MFSYQGKNVVVVGGTSGINLAIAVHFSQAGANVAVASRSVEKVDAAVELLKQANPNGEHLGVCFDVRDLEALSKGFATIS
DAFSTIDVLVSGAAGNFPSTAEKLSENGFKSVMDIDLLGSFQVLKQAYPLMSDTGGAIIQISAPQAFVPMPMQVHVCAAK
AGVDMLTKTLAIEWGRKGIRINSIVPGPIAGTEGFNRLAPSEELQAHVAQGVPLKRNGRCEDIANAALFLASDMASYITG
TVLPVDGGWSLGGAGSAIAEIGQLARRN

Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=42.3387096774194, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=35.7142857142857, Blast_Score=141, Evalue=6e-34,
Organism=Homo sapiens, GI4503301, Length=248, Percent_Identity=35.0806451612903, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=34.6774193548387, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=33.1983805668016, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=32.0987654320988, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=29.1497975708502, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=26.8292682926829, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=30.7086614173228, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI59889578, Length=176, Percent_Identity=32.9545454545455, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=32.4324324324324, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI31542939, Length=185, Percent_Identity=31.3513513513514, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=29.0836653386454, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=29.6153846153846, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=29.6875, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=30.2788844621514, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=28.6885245901639, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=26.9076305220884, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=28.8617886178862, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=27.4509803921569, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=27.6923076923077, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787545, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=27.34375, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=25.7028112449799, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=269, Percent_Identity=33.8289962825279, Blast_Score=140, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17536651, Length=268, Percent_Identity=32.4626865671642, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17561272, Length=237, Percent_Identity=33.7552742616034, Blast_Score=126, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17560676, Length=242, Percent_Identity=31.8181818181818, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=29.5880149812734, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=34.2741935483871, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=32.1285140562249, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=26.9662921348315, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=27.007299270073, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=29.5454545454545, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=27.0676691729323, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=26.7924528301887, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=30.4832713754647, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=27.4074074074074, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=25.8426966292135, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=26.2948207171315, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=28.8, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=27.3408239700375, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=25.4032258064516, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=26.615969581749, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=27.4074074074074, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=25.5555555555556, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=27.5471698113208, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=26.7657992565056, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=24.6212121212121, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=25, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=25.9398496240602, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=26.8199233716475, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=40.0793650793651, Blast_Score=163, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=30.0395256916996, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=30, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=30.1587301587302, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=31.1023622047244, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=29.2490118577075, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=27.2, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=31.7829457364341, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=28.2258064516129, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21356301, Length=216, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859837, Length=216, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 27813; Mature: 27813

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSYQGKNVVVVGGTSGINLAIAVHFSQAGANVAVASRSVEKVDAAVELLKQANPNGEHL
CCCCCCCEEEEEECCCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCEE
GVCFDVRDLEALSKGFATISDAFSTIDVLVSGAAGNFPSTAEKLSENGFKSVMDIDLLGS
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
FQVLKQAYPLMSDTGGAIIQISAPQAFVPMPMQVHVCAAKAGVDMLTKTLAIEWGRKGIR
HHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEE
INSIVPGPIAGTEGFNRLAPSEELQAHVAQGVPLKRNGRCEDIANAALFLASDMASYITG
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TVLPVDGGWSLGGAGSAIAEIGQLARRN
EEEECCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MFSYQGKNVVVVGGTSGINLAIAVHFSQAGANVAVASRSVEKVDAAVELLKQANPNGEHL
CCCCCCCEEEEEECCCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCEE
GVCFDVRDLEALSKGFATISDAFSTIDVLVSGAAGNFPSTAEKLSENGFKSVMDIDLLGS
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
FQVLKQAYPLMSDTGGAIIQISAPQAFVPMPMQVHVCAAKAGVDMLTKTLAIEWGRKGIR
HHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEE
INSIVPGPIAGTEGFNRLAPSEELQAHVAQGVPLKRNGRCEDIANAALFLASDMASYITG
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TVLPVDGGWSLGGAGSAIAEIGQLARRN
EEEECCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]