Click here to switch to the map view.

The map label for this gene is pgm [H]

Identifier: 157961877

GI number: 157961877

Start: 2487611

End: 2489257

Strand: Direct

Name: pgm [H]

Synonym: Spea_2056

Alternate gene names: 157961877

Gene position: 2487611-2489257 (Clockwise)

Preceding gene: 157961876

Following gene: 157961881

Centisome position: 48.07

GC content: 44.75

Gene sequence:

>1647_bases
TTGGCTATACATAAGAGAGCAGGATTGATTGCTGAGCAAAAGGATTTGGTCAATATCCCAAAACTCGTTAGCCTGTATTA
TTGCTTAACGCCCGATGTGGAAAATGTGAGTCAAAAGGTCACTTTTGGTACCTCGGGCCATCGTGGTAGTGCTGCACAAA
GAAGTTTTAATGAAGCGCATATTATTGCTATCGCACAAGCCGTTGCAGACTATCGTAAGCAAGCCAATATCACGGGTAAG
TTGATATTGGGCATAGATACGCATGCATTATCACAACCTGCTGCAATGTCGGTTATAGAAGTATTAGTCGCTAACCAAGT
GAGTGTGGTTGTACATCAAAATGACGGTTTTACACCCACTCCTGTGGTTTCTCACGCCATTATTAGTGCCAACTTAGGTA
AAAGTGATACTGATGAGTTAGTGGATGGTCTTATTGTTACGCCTTCGCACAATCCACCACAAGATGGCGGTATTAAATAT
AACCCACCACATGGCGGCCCGGCGGAAGGTGAGATCACCACTTGGATCCAAGACAAAGCCAATCAATATTTGGCCAATGA
TTTAGCCGGTGTAAAGCGCATTAGTTACAGTGAAGCGCTTAGCAGTGACTACCTTATCGATGAAGACTTTATCACGCCTT
ATATCACCGACTTAAATCGTGTTATCAATATGCAAGCGATTGCAGACGCTAAGATCCGTTTGGGCGTCGACCCTCTGGGT
GGTTCGGGCGTCCACTACTGGGCACCAATTGCAAAGCATTACGGTATAGATATCACGGTACTTAATACTCATGTCGATCC
AAGTTTCAGTTTTATGCCGCTAGATAAGGACGGTAAGATCCGTATGGATTGCTCGTCACCTTATGCAATGGCTGGACTGC
TAGAGCATAAAGATAGCTTTGATCTTTGCTTGGGTAATGACCCAGATTTTGATCGTCATGGTATCGTCTGTCCAGGTAGC
GGCCTGATGAATCCAAATCATTTCCTTGCTGTCGCAATCGACTATTTGGTAACCCATCGTCCACAATGGACAGAGCAGAT
GGTGATCGGTAAGACGCTGGTATCGAGTGCGATGATCGATAAAGTCTGTCAGATGCATAATAAACCGATGTCAGAGGTGC
CAGTCGGCTTTAAATGGTTTGTCGATGGGCTTGCTAATAGTGAGTTTGCCTTTGGCGGTGAAGAAAGTGCCGGTGCAGCC
TTTTTAAGGCTCGATGGCAGCACTTGGTGTACCGATAAAGATGGCTTTATTTTGTGTCTACTAGCGGCTGAAATTCTTGC
TGTTACCGGAAAAACACCTCAGCAAAGATACGATGAACTCGAAGCACAATTTGGTAAGAGTTTTTACCAGCGCATAGACA
GTCCTGTGAGCCTTGAGGATAAAGCTAAGTTTTCCAGAATTGAAGCCGATTCGATTCACACAGAGACACTAGCGGGCGAT
GAAATATTGCAGAAGTTGACTCATGCTCCAGGTAACAATGCGGCTATCGGTGGCATTAAAGTTGTGACAGAAAATGGCTG
GTTCGCTGCTCGACCATCTGGTACAGAGGCGCTATTTAAGCTTTATGGTGAAAGTTTTGTTAGCCAAGAGCATCTTACTT
GCTTACTAAAAGAAGCTCAGCAGATTGTGGCTGCTGCATTAAGATAA

Upstream 100 bases:

>100_bases
TTGCCGATATCATAGAAAGAATTTAACGATATAAAGCGTTAACGTAAAATATATAGACTTACCATTTATGAATTCATAAA
GGTAATAGAAGGAGAGGGAC

Downstream 100 bases:

>100_bases
ATGGATCGTTTGTTATAAGAGTTAAGTATCAAACACCGCAGGCACCTTTGATAGCTTGAGCATATAGTTAAACATTTAGT
TGAGCATATAGCTTGAAATC

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MAIHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVENVSQKVTFGTSGHRGSAAQRSFNEAHIIAIAQAVADYRKQANITGK
LILGIDTHALSQPAAMSVIEVLVANQVSVVVHQNDGFTPTPVVSHAIISANLGKSDTDELVDGLIVTPSHNPPQDGGIKY
NPPHGGPAEGEITTWIQDKANQYLANDLAGVKRISYSEALSSDYLIDEDFITPYITDLNRVINMQAIADAKIRLGVDPLG
GSGVHYWAPIAKHYGIDITVLNTHVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLEHKDSFDLCLGNDPDFDRHGIVCPGS
GLMNPNHFLAVAIDYLVTHRPQWTEQMVIGKTLVSSAMIDKVCQMHNKPMSEVPVGFKWFVDGLANSEFAFGGEESAGAA
FLRLDGSTWCTDKDGFILCLLAAEILAVTGKTPQQRYDELEAQFGKSFYQRIDSPVSLEDKAKFSRIEADSIHTETLAGD
EILQKLTHAPGNNAAIGGIKVVTENGWFAARPSGTEALFKLYGESFVSQEHLTCLLKEAQQIVAAALR

Sequences:

>Translated_548_residues
MAIHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVENVSQKVTFGTSGHRGSAAQRSFNEAHIIAIAQAVADYRKQANITGK
LILGIDTHALSQPAAMSVIEVLVANQVSVVVHQNDGFTPTPVVSHAIISANLGKSDTDELVDGLIVTPSHNPPQDGGIKY
NPPHGGPAEGEITTWIQDKANQYLANDLAGVKRISYSEALSSDYLIDEDFITPYITDLNRVINMQAIADAKIRLGVDPLG
GSGVHYWAPIAKHYGIDITVLNTHVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLEHKDSFDLCLGNDPDFDRHGIVCPGS
GLMNPNHFLAVAIDYLVTHRPQWTEQMVIGKTLVSSAMIDKVCQMHNKPMSEVPVGFKWFVDGLANSEFAFGGEESAGAA
FLRLDGSTWCTDKDGFILCLLAAEILAVTGKTPQQRYDELEAQFGKSFYQRIDSPVSLEDKAKFSRIEADSIHTETLAGD
EILQKLTHAPGNNAAIGGIKVVTENGWFAARPSGTEALFKLYGESFVSQEHLTCLLKEAQQIVAAALR
>Mature_547_residues
AIHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVENVSQKVTFGTSGHRGSAAQRSFNEAHIIAIAQAVADYRKQANITGKL
ILGIDTHALSQPAAMSVIEVLVANQVSVVVHQNDGFTPTPVVSHAIISANLGKSDTDELVDGLIVTPSHNPPQDGGIKYN
PPHGGPAEGEITTWIQDKANQYLANDLAGVKRISYSEALSSDYLIDEDFITPYITDLNRVINMQAIADAKIRLGVDPLGG
SGVHYWAPIAKHYGIDITVLNTHVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLEHKDSFDLCLGNDPDFDRHGIVCPGSG
LMNPNHFLAVAIDYLVTHRPQWTEQMVIGKTLVSSAMIDKVCQMHNKPMSEVPVGFKWFVDGLANSEFAFGGEESAGAAF
LRLDGSTWCTDKDGFILCLLAAEILAVTGKTPQQRYDELEAQFGKSFYQRIDSPVSLEDKAKFSRIEADSIHTETLAGDE
ILQKLTHAPGNNAAIGGIKVVTENGWFAARPSGTEALFKLYGESFVSQEHLTCLLKEAQQIVAAALR

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=516, Percent_Identity=21.5116279069767, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI290463102, Length=395, Percent_Identity=25.3164556962025, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786904, Length=548, Percent_Identity=56.7518248175182, Blast_Score=652, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=548, Percent_Identity=26.0948905109489, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323752, Length=453, Percent_Identity=25.1655629139073, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322722, Length=471, Percent_Identity=25.6900212314225, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17864244, Length=438, Percent_Identity=24.4292237442922, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59531; Mature: 59400

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVENVSQKVTFGTSGHRGSAAQRSFNEAH
CCCCCCCCCCCCCHHHCCHHHHHHHHHEECCCHHHHHHEEEECCCCCCCCHHHHCCCCHH
IIAIAQAVADYRKQANITGKLILGIDTHALSQPAAMSVIEVLVANQVSVVVHQNDGFTPT
HHHHHHHHHHHHHHCCCCEEEEEEECHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCC
PVVSHAIISANLGKSDTDELVDGLIVTPSHNPPQDGGIKYNPPHGGPAEGEITTWIQDKA
HHHHHHHHCCCCCCCCHHHHHCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEEHHHHHH
NQYLANDLAGVKRISYSEALSSDYLIDEDFITPYITDLNRVINMQAIADAKIRLGVDPLG
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCC
GSGVHYWAPIAKHYGIDITVLNTHVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLEHKDSF
CCCCCHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCEEEECCCCHHHHHHHHCCCCC
DLCLGNDPDFDRHGIVCPGSGLMNPNHFLAVAIDYLVTHRPQWTEQMVIGKTLVSSAMID
CEEECCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KVCQMHNKPMSEVPVGFKWFVDGLANSEFAFGGEESAGAAFLRLDGSTWCTDKDGFILCL
HHHHHHCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCHHH
LAAEILAVTGKTPQQRYDELEAQFGKSFYQRIDSPVSLEDKAKFSRIEADSIHTETLAGD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHCCHH
EILQKLTHAPGNNAAIGGIKVVTENGWFAARPSGTEALFKLYGESFVSQEHLTCLLKEAQ
HHHHHHHCCCCCCCEECEEEEEEECCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
QIVAAALR
HHHHHHCC
>Mature Secondary Structure 
AIHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVENVSQKVTFGTSGHRGSAAQRSFNEAH
CCCCCCCCCCCCHHHCCHHHHHHHHHEECCCHHHHHHEEEECCCCCCCCHHHHCCCCHH
IIAIAQAVADYRKQANITGKLILGIDTHALSQPAAMSVIEVLVANQVSVVVHQNDGFTPT
HHHHHHHHHHHHHHCCCCEEEEEEECHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCC
PVVSHAIISANLGKSDTDELVDGLIVTPSHNPPQDGGIKYNPPHGGPAEGEITTWIQDKA
HHHHHHHHCCCCCCCCHHHHHCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEEHHHHHH
NQYLANDLAGVKRISYSEALSSDYLIDEDFITPYITDLNRVINMQAIADAKIRLGVDPLG
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCC
GSGVHYWAPIAKHYGIDITVLNTHVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLEHKDSF
CCCCCHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCEEEECCCCHHHHHHHHCCCCC
DLCLGNDPDFDRHGIVCPGSGLMNPNHFLAVAIDYLVTHRPQWTEQMVIGKTLVSSAMID
CEEECCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KVCQMHNKPMSEVPVGFKWFVDGLANSEFAFGGEESAGAAFLRLDGSTWCTDKDGFILCL
HHHHHHCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCHHH
LAAEILAVTGKTPQQRYDELEAQFGKSFYQRIDSPVSLEDKAKFSRIEADSIHTETLAGD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHCCHH
EILQKLTHAPGNNAAIGGIKVVTENGWFAARPSGTEALFKLYGESFVSQEHLTCLLKEAQ
HHHHHHHCCCCCCCEECEEEEEEECCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
QIVAAALR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]