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The map label for this gene is hlyB [H]

Identifier: 157961818

GI number: 157961818

Start: 2420055

End: 2421695

Strand: Reverse

Name: hlyB [H]

Synonym: Spea_1997

Alternate gene names: 157961818

Gene position: 2421695-2420055 (Counterclockwise)

Preceding gene: 157961820

Following gene: 157961817

Centisome position: 46.8

GC content: 45.4

Gene sequence:

>1641_bases
ATGATCGCCCTCTTAAGACAGTTTACAATTCTACAACGTCTAATTTTAATGCTAATGCTAGCCGCTATCGGTACCGTTTG
CTTTGCCAGTTTTTCGATCAATGAACAGTACAACAACCTTATCGCTCAAAAATGGCTTCAAAACGATGCCCAAATCAACA
CGGCCGTCAGCATTATCGAAGCTCATAACAAACAAGTTGAAGATCTCAACCTCACTCTCGTTAACGCCAAACAAGCTGCA
GCTTATCTAATTAATCAAATACATTTTGGCAACGATGGCTATTTCATCATATTAGATGAACAGCGCAATATTATCGCCCA
CGGCGCCGACGCTAGTGCCATTAACCAAAATGCCACCACACTCTTTAGTTCTCAAGACCCCGTCAACCTCGAGACTTTAG
TTAGCGCAGCTGCCCATCAACCTGTTGCCAAGTCGCAAATTAACTTCCCCAATCCGAGTAGCGGTCAGTTGGAGCCCAAG
CTCGTTGAAGCCAGACAATACGCCCCCTGGGACTGGACTATTATTACTGGCAGCTATATGAGCGATGTGAGTGATGTGAT
GTATTCGATGGCTTTCGATTACCTCGCAATCATGTTGATGATCTCAATTCCCATCTTTCTTTTTTTCCTAGTGCTTAACA
TTTCCATAACCGCCCCGCTAAAAGAAGCGATTACGGCGATGAAAGACATAGCGCAAGGAGAAGGTGATTTAACCCAAAAG
CTGCCAACAAAAGGCAAAGATGAAGTAGCAGAATTGGCCCAAGCCTTCAATTTATTTGTGTTGAAAATTAGGGATATGGT
CGCCCAGCTACAACCAATAGGCCAAAGTTTGGATAAAGATGCTATCGGGTTACTCACTGCAGTTGAGGAGTCAAACAGTA
GTGTCGAGCATCTACACCAACAAACGTCAAGCGTAGCGACGGCAATTAACCAGATGCTATCGACGACTCAAGAAATGGCC
ACCAGTACCAACCAAGCAGCTGATGCCGCGAATAGCGTAAAGCACCAAGCTCAGCAAAGTATGTCAATGATGGACTCGAC
ACTCGACAATGTGCAGCATCTTGCAGATGAGCTACAGCATGCTCAGCAGCTCACCCATGCCCTTGGTCAATCATCGCTAC
AGATAGGCAGTATCCTTGATGTGATCCGCGCAATAGCCGAACAAACCAATCTACTTGCCCTCAATGCCGCTATCGAAGCT
GCGCGTGCGGGAGCTCATGGCCGCGGTTTTGCCGTCGTAGCCGATGAGGTGCGTGCCTTAGCGACACGTACACAAGACTC
CACCAACGAAATTCAAAATATCATCAAAGATATTCAATCGGGCGTAAATCTTGTGGTGGCCAGTAACGAGCAAAATCAAC
ATCAATCACAACAAGTCCAGACCCAAGCAAAGGATGTCAGCGATTCATTGGCCGATATCCTTAACTTAATTGCTCATATC
AGTGATATGAATACCCAACTCGCCAGTGCAACCGAAGAGCAATCGATTGTCACAGAGGAGATCAATCGCAACATTTGCAC
CATTACAGAATTAACAGAAGTGTCGGTAAAAGCTAATGAAAGTAACCACAGTGCAGCGATTTCTCTTCAATCGATCAGTA
AAGACTGCTCGCAAACATTAGGCCAGTTTAAAGTTAACTAG

Upstream 100 bases:

>100_bases
ACAGTTAACATTTTTAAAATAAACATAAACTTACTATTTCCCATCCTCATCATTAAGGTTAAGTTTAAACAATGTTATCG
TAAACAGAGCAACACAGAAT

Downstream 100 bases:

>100_bases
CGCCCAGTCAGACTTTAGCTCGAGGGCGACATTGCCCCTCGCGCTATCGGTCTTTTATGGTAAGCTAAATTCACTAATGG
AATTTATCTAAGAGTGAATT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLIAQKWLQNDAQINTAVSIIEAHNKQVEDLNLTLVNAKQAA
AYLINQIHFGNDGYFIILDEQRNIIAHGADASAINQNATTLFSSQDPVNLETLVSAAAHQPVAKSQINFPNPSSGQLEPK
LVEARQYAPWDWTIITGSYMSDVSDVMYSMAFDYLAIMLMISIPIFLFFLVLNISITAPLKEAITAMKDIAQGEGDLTQK
LPTKGKDEVAELAQAFNLFVLKIRDMVAQLQPIGQSLDKDAIGLLTAVEESNSSVEHLHQQTSSVATAINQMLSTTQEMA
TSTNQAADAANSVKHQAQQSMSMMDSTLDNVQHLADELQHAQQLTHALGQSSLQIGSILDVIRAIAEQTNLLALNAAIEA
ARAGAHGRGFAVVADEVRALATRTQDSTNEIQNIIKDIQSGVNLVVASNEQNQHQSQQVQTQAKDVSDSLADILNLIAHI
SDMNTQLASATEEQSIVTEEINRNICTITELTEVSVKANESNHSAAISLQSISKDCSQTLGQFKVN

Sequences:

>Translated_546_residues
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLIAQKWLQNDAQINTAVSIIEAHNKQVEDLNLTLVNAKQAA
AYLINQIHFGNDGYFIILDEQRNIIAHGADASAINQNATTLFSSQDPVNLETLVSAAAHQPVAKSQINFPNPSSGQLEPK
LVEARQYAPWDWTIITGSYMSDVSDVMYSMAFDYLAIMLMISIPIFLFFLVLNISITAPLKEAITAMKDIAQGEGDLTQK
LPTKGKDEVAELAQAFNLFVLKIRDMVAQLQPIGQSLDKDAIGLLTAVEESNSSVEHLHQQTSSVATAINQMLSTTQEMA
TSTNQAADAANSVKHQAQQSMSMMDSTLDNVQHLADELQHAQQLTHALGQSSLQIGSILDVIRAIAEQTNLLALNAAIEA
ARAGAHGRGFAVVADEVRALATRTQDSTNEIQNIIKDIQSGVNLVVASNEQNQHQSQQVQTQAKDVSDSLADILNLIAHI
SDMNTQLASATEEQSIVTEEINRNICTITELTEVSVKANESNHSAAISLQSISKDCSQTLGQFKVN
>Mature_546_residues
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLIAQKWLQNDAQINTAVSIIEAHNKQVEDLNLTLVNAKQAA
AYLINQIHFGNDGYFIILDEQRNIIAHGADASAINQNATTLFSSQDPVNLETLVSAAAHQPVAKSQINFPNPSSGQLEPK
LVEARQYAPWDWTIITGSYMSDVSDVMYSMAFDYLAIMLMISIPIFLFFLVLNISITAPLKEAITAMKDIAQGEGDLTQK
LPTKGKDEVAELAQAFNLFVLKIRDMVAQLQPIGQSLDKDAIGLLTAVEESNSSVEHLHQQTSSVATAINQMLSTTQEMA
TSTNQAADAANSVKHQAQQSMSMMDSTLDNVQHLADELQHAQQLTHALGQSSLQIGSILDVIRAIAEQTNLLALNAAIEA
ARAGAHGRGFAVVADEVRALATRTQDSTNEIQNIIKDIQSGVNLVVASNEQNQHQSQQVQTQAKDVSDSLADILNLIAHI
SDMNTQLASATEEQSIVTEEINRNICTITELTEVSVKANESNHSAAISLQSISKDCSQTLGQFKVN

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=327, Percent_Identity=28.7461773700306, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788195, Length=299, Percent_Identity=29.4314381270903, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787690, Length=358, Percent_Identity=27.9329608938547, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788194, Length=282, Percent_Identity=29.0780141843972, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789453, Length=341, Percent_Identity=29.3255131964809, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59421; Mature: 59421

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLIAQKWLQNDAQINTAVSIIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
AHNKQVEDLNLTLVNAKQAAAYLINQIHFGNDGYFIILDEQRNIIAHGADASAINQNATT
HHCCCCCCCEEEEECHHHHHHHHHHHHEECCCCEEEEEECCCCEEEECCCHHHCCCCCCE
LFSSQDPVNLETLVSAAAHQPVAKSQINFPNPSSGQLEPKLVEARQYAPWDWTIITGSYM
EECCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECHHH
SDVSDVMYSMAFDYLAIMLMISIPIFLFFLVLNISITAPLKEAITAMKDIAQGEGDLTQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHH
LPTKGKDEVAELAQAFNLFVLKIRDMVAQLQPIGQSLDKDAIGLLTAVEESNSSVEHLHQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHH
QTSSVATAINQMLSTTQEMATSTNQAADAANSVKHQAQQSMSMMDSTLDNVQHLADELQH
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQLTHALGQSSLQIGSILDVIRAIAEQTNLLALNAAIEAARAGAHGRGFAVVADEVRAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHH
ATRTQDSTNEIQNIIKDIQSGVNLVVASNEQNQHQSQQVQTQAKDVSDSLADILNLIAHI
HHHCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDMNTQLASATEEQSIVTEEINRNICTITELTEVSVKANESNHSAAISLQSISKDCSQTL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHEEECCCCCCHHEEEHHHHHHHHHHHH
GQFKVN
HCCCCC
>Mature Secondary Structure
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLIAQKWLQNDAQINTAVSIIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
AHNKQVEDLNLTLVNAKQAAAYLINQIHFGNDGYFIILDEQRNIIAHGADASAINQNATT
HHCCCCCCCEEEEECHHHHHHHHHHHHEECCCCEEEEEECCCCEEEECCCHHHCCCCCCE
LFSSQDPVNLETLVSAAAHQPVAKSQINFPNPSSGQLEPKLVEARQYAPWDWTIITGSYM
EECCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECHHH
SDVSDVMYSMAFDYLAIMLMISIPIFLFFLVLNISITAPLKEAITAMKDIAQGEGDLTQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHH
LPTKGKDEVAELAQAFNLFVLKIRDMVAQLQPIGQSLDKDAIGLLTAVEESNSSVEHLHQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHH
QTSSVATAINQMLSTTQEMATSTNQAADAANSVKHQAQQSMSMMDSTLDNVQHLADELQH
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQLTHALGQSSLQIGSILDVIRAIAEQTNLLALNAAIEAARAGAHGRGFAVVADEVRAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHH
ATRTQDSTNEIQNIIKDIQSGVNLVVASNEQNQHQSQQVQTQAKDVSDSLADILNLIAHI
HHHCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDMNTQLASATEEQSIVTEEINRNICTITELTEVSVKANESNHSAAISLQSISKDCSQTL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHEEECCCCCCHHEEEHHHHHHHHHHHH
GQFKVN
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]