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The map label for this gene is hda [H]

Identifier: 157961790

GI number: 157961790

Start: 2392797

End: 2393507

Strand: Direct

Name: hda [H]

Synonym: Spea_1967

Alternate gene names: 157961790

Gene position: 2392797-2393507 (Clockwise)

Preceding gene: 157961789

Following gene: 157961795

Centisome position: 46.24

GC content: 43.88

Gene sequence:

>711_bases
GTGAAGTCAAACTCTCCTTTACAATTATCACTGCCAGTTCATCTACCTGATGATGAAACCTTCAATAGTTATTATCCTGC
TACGGGTAATGATGAGCTTATTCAAAGTTTACAAGAGTGCGCGGAAGGCAAATCTAATGGGGCTGTGTTTTTGTGGGGTC
CTGAAAAATCAGGACGCACCCACCTTATGCATGCTGCCTGCGCTCACGCCAATGATCTTGGTCGAAGTAGTTTTTATATT
CCACTGGGGATCCATGCGAGTATTTCTACCGCCTTATTAGAAGGCCTAGAAAAATTGGATTTAGTCTGTATCGATGATGT
CGATGCGATTGCTGGCCACCCATTATGGGAAGAGGCGATATTTGATCTCTATAATCGAATTTCAGAACAAAAGACCTGTT
CGCTCGTCGTTAGTGCGAGTGTATCACCGAGTGATAGTGGTTTTTCTTTGCCAGATCTTGTCTCTCGCATGCAGTGGGGG
CTTAATTATCAGCTGCAGCCTATGGCTGATGAAGAAAAGCTTGCTGCGCTACAACGCCGAGCTGCGATGCGAGGCTTACA
ACTACCAGAAGATGTAGGACGTTTTCTACTGAATCGTTTGGCTAGAGATCTAAGAACTCTGTTTGATGTTTTGGATAGGC
TCGATAAAGCTTCCATGGTTCATCAACGTAAACTGACTATTCCATTTATTAAAGAAATGCTGCGCCTCTAA

Upstream 100 bases:

>100_bases
CAGATCTATTATTGGAAAGGGCAATAGCTCCCAATCGAGAGGCACACATGCTACCATGTGTGCCTAATATAGAAATATAG
CGCCATTGAGAAGTACCTGA

Downstream 100 bases:

>100_bases
GCGTAGTTATTGGTTCAGCACAAACTAAAAAGCCCAGATCTGCATCTGGGCTTTTACGTTTCTATAATTGTCCCGTCCTG
AGATAAGTTAGCGAAAGTGA

Product: DNA replication initiation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKSNSPLQLSLPVHLPDDETFNSYYPATGNDELIQSLQECAEGKSNGAVFLWGPEKSGRTHLMHAACAHANDLGRSSFYI
PLGIHASISTALLEGLEKLDLVCIDDVDAIAGHPLWEEAIFDLYNRISEQKTCSLVVSASVSPSDSGFSLPDLVSRMQWG
LNYQLQPMADEEKLAALQRRAAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL

Sequences:

>Translated_236_residues
MKSNSPLQLSLPVHLPDDETFNSYYPATGNDELIQSLQECAEGKSNGAVFLWGPEKSGRTHLMHAACAHANDLGRSSFYI
PLGIHASISTALLEGLEKLDLVCIDDVDAIAGHPLWEEAIFDLYNRISEQKTCSLVVSASVSPSDSGFSLPDLVSRMQWG
LNYQLQPMADEEKLAALQRRAAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL
>Mature_236_residues
MKSNSPLQLSLPVHLPDDETFNSYYPATGNDELIQSLQECAEGKSNGAVFLWGPEKSGRTHLMHAACAHANDLGRSSFYI
PLGIHASISTALLEGLEKLDLVCIDDVDAIAGHPLWEEAIFDLYNRISEQKTCSLVVSASVSPSDSGFSLPDLVSRMQWG
LNYQLQPMADEEKLAALQRRAAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=233, Percent_Identity=52.3605150214592, Blast_Score=253, Evalue=6e-69,
Organism=Escherichia coli, GI2367267, Length=231, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 26320; Mature: 26320

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNSPLQLSLPVHLPDDETFNSYYPATGNDELIQSLQECAEGKSNGAVFLWGPEKSGRT
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCH
HLMHAACAHANDLGRSSFYIPLGIHASISTALLEGLEKLDLVCIDDVDAIAGHPLWEEAI
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEECCCHHHHCCCHHHHHH
FDLYNRISEQKTCSLVVSASVSPSDSGFSLPDLVSRMQWGLNYQLQPMADEEKLAALQRR
HHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHH
AAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MKSNSPLQLSLPVHLPDDETFNSYYPATGNDELIQSLQECAEGKSNGAVFLWGPEKSGRT
CCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCH
HLMHAACAHANDLGRSSFYIPLGIHASISTALLEGLEKLDLVCIDDVDAIAGHPLWEEAI
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEECCCHHHHCCCHHHHHH
FDLYNRISEQKTCSLVVSASVSPSDSGFSLPDLVSRMQWGLNYQLQPMADEEKLAALQRR
HHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHH
AAMRGLQLPEDVGRFLLNRLARDLRTLFDVLDRLDKASMVHQRKLTIPFIKEMLRL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA