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The map label for this gene is yeaD [H]

Identifier: 157961675

GI number: 157961675

Start: 2252105

End: 2252950

Strand: Reverse

Name: yeaD [H]

Synonym: Spea_1851

Alternate gene names: 157961675

Gene position: 2252950-2252105 (Counterclockwise)

Preceding gene: 157961678

Following gene: 157961674

Centisome position: 43.54

GC content: 44.92

Gene sequence:

>846_bases
ATGGGTTCGGTCACCACCAGTAAACATGCTAACGGGTTAGAATATGTCGACGTCAATACTCCTTTGTGTAAGGCCAGAAT
TTTTATGCAAGGGGCACAAATTGATTATTTTGAGCCTGTAGGGAAAAAACCATTACTTTGGGTATCCAGCGCCGATGATT
ATCAGCCAGGCAGTGGTATTCGTGGTGGCATCCCTGTTTGTTGGCCTTGGTTTGGCATGAGTGATAACCCTGACTTCCCA
CAGCATGGCTTTGCACGTACCCGCATTTGGTCACTGGAGTCAGTGAAAATGCGTAATCAAGTTGTTGATCTGAAATTTAC
CCTTAAGATAAGCGAAGAAGATAAGCAATACTGGCCCCACGATACCAGTGTTGAGTTACTGTTCAGCCTAAGCGACACGC
TGTCAGTGAGTTTGGTCAACACCAATCACTGTGATTACGATGTCAGCCTAACACAGGCGCTACACAGCTATTTCCCAATT
AATGATATTCATCAGTTAACCGCAACAGGCTTTGAAACATCTAAGTATATTGAATTTGCTAAAGGGCCGTTCCAGCAAGA
GGGAGATAGCGTCGATTTCACCCGTGAAACTGACCGCGTCTATACCGACTTAGGCGAATGCCAAGAATTACATACCCCAG
ATGGTGTGATAGAAGTACGCCGTGAAAACAGCAGCAGCGCCGTGCTTTGGAACCCTTGGATAGAAAAATCGACTCGTTTA
TCTCGATTCAATAGCGATGACTATCAGACCATGGTCTGCCTAGAGGCTGCTAATGTTTTAGAAGATAAGCTAACACTCGC
GCCAAACGAGAGTCATACTTTAACGACTACTATTCGTTGGAAATAA

Upstream 100 bases:

>100_bases
CATTACCGTAAATACAGTCGAAAGAATGCTTATCTAGATCTTGAAAAACGGGTAAGCTAATTCAATTATTCGTGCTAACG
CTATGAAAGGACAACTCCAA

Downstream 100 bases:

>100_bases
TCATAGCAAGAGGTCTACAATCGTAGATCTCTTCTAGCGCAATCAAGAATCCCCGTAGCTCATATCGATGAGGCAAAGGG
AACCACAGCAAAGATATTAC

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MGSVTTSKHANGLEYVDVNTPLCKARIFMQGAQIDYFEPVGKKPLLWVSSADDYQPGSGIRGGIPVCWPWFGMSDNPDFP
QHGFARTRIWSLESVKMRNQVVDLKFTLKISEEDKQYWPHDTSVELLFSLSDTLSVSLVNTNHCDYDVSLTQALHSYFPI
NDIHQLTATGFETSKYIEFAKGPFQQEGDSVDFTRETDRVYTDLGECQELHTPDGVIEVRRENSSSAVLWNPWIEKSTRL
SRFNSDDYQTMVCLEAANVLEDKLTLAPNESHTLTTTIRWK

Sequences:

>Translated_281_residues
MGSVTTSKHANGLEYVDVNTPLCKARIFMQGAQIDYFEPVGKKPLLWVSSADDYQPGSGIRGGIPVCWPWFGMSDNPDFP
QHGFARTRIWSLESVKMRNQVVDLKFTLKISEEDKQYWPHDTSVELLFSLSDTLSVSLVNTNHCDYDVSLTQALHSYFPI
NDIHQLTATGFETSKYIEFAKGPFQQEGDSVDFTRETDRVYTDLGECQELHTPDGVIEVRRENSSSAVLWNPWIEKSTRL
SRFNSDDYQTMVCLEAANVLEDKLTLAPNESHTLTTTIRWK
>Mature_280_residues
GSVTTSKHANGLEYVDVNTPLCKARIFMQGAQIDYFEPVGKKPLLWVSSADDYQPGSGIRGGIPVCWPWFGMSDNPDFPQ
HGFARTRIWSLESVKMRNQVVDLKFTLKISEEDKQYWPHDTSVELLFSLSDTLSVSLVNTNHCDYDVSLTQALHSYFPIN
DIHQLTATGFETSKYIEFAKGPFQQEGDSVDFTRETDRVYTDLGECQELHTPDGVIEVRRENSSSAVLWNPWIEKSTRLS
RFNSDDYQTMVCLEAANVLEDKLTLAPNESHTLTTTIRWK

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=284, Percent_Identity=32.0422535211268, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323746, Length=239, Percent_Identity=29.7071129707113, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19921284, Length=232, Percent_Identity=28.448275862069, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 31974; Mature: 31843

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVTTSKHANGLEYVDVNTPLCKARIFMQGAQIDYFEPVGKKPLLWVSSADDYQPGSGI
CCCCCCCCCCCCCEEEECCCCHHEEEEEEECCCEEEECCCCCCCEEEEECCCCCCCCCCC
RGGIPVCWPWFGMSDNPDFPQHGFARTRIWSLESVKMRNQVVDLKFTLKISEEDKQYWPH
CCCCCEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHCCEEEEEEEEEEECCCCHHHCCC
DTSVELLFSLSDTLSVSLVNTNHCDYDVSLTQALHSYFPINDIHQLTATGFETSKYIEFA
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHH
KGPFQQEGDSVDFTRETDRVYTDLGECQELHTPDGVIEVRRENSSSAVLWNPWIEKSTRL
CCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCHHH
SRFNSDDYQTMVCLEAANVLEDKLTLAPNESHTLTTTIRWK
HHCCCCCCEEEEEHHHHHHHHHHEEECCCCCCEEEEEEEEC
>Mature Secondary Structure 
GSVTTSKHANGLEYVDVNTPLCKARIFMQGAQIDYFEPVGKKPLLWVSSADDYQPGSGI
CCCCCCCCCCCCEEEECCCCHHEEEEEEECCCEEEECCCCCCCEEEEECCCCCCCCCCC
RGGIPVCWPWFGMSDNPDFPQHGFARTRIWSLESVKMRNQVVDLKFTLKISEEDKQYWPH
CCCCCEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHHCCEEEEEEEEEEECCCCHHHCCC
DTSVELLFSLSDTLSVSLVNTNHCDYDVSLTQALHSYFPINDIHQLTATGFETSKYIEFA
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHH
KGPFQQEGDSVDFTRETDRVYTDLGECQELHTPDGVIEVRRENSSSAVLWNPWIEKSTRL
CCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCHHH
SRFNSDDYQTMVCLEAANVLEDKLTLAPNESHTLTTTIRWK
HHCCCCCCEEEEEHHHHHHHHHHEEECCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]