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The map label for this gene is dnaQ [H]

Identifier: 157961523

GI number: 157961523

Start: 2064506

End: 2065192

Strand: Direct

Name: dnaQ [H]

Synonym: Spea_1698

Alternate gene names: 157961523

Gene position: 2064506-2065192 (Clockwise)

Preceding gene: 157961522

Following gene: 157961524

Centisome position: 39.9

GC content: 45.41

Gene sequence:

>687_bases
ATGGAAAATTTGAGAAATTTATACTTAAAAACACGACTACAGTTTAATGCCTTGCTATCTCAAGATACCGTGATTAGTGG
TTATCATCGCGCATTAGTGACACAGATCTCTAAGCCTTTATCGCAACTGCCCTTGATGGCAGTGGATCTGGAGATGACAG
GGTTAAATAGCCAGTTCGATCAGATCTTGAGTATCGGTCTGATACCCATTCGCAACGGTTTACTGCAAGTATCCCACTCG
AAGCATCTGTTGGTGAGCATAGATGGCAGCGTCGGTGACAGCGCGGTGATCCATGGAATTGTAGATAACCAATTAACCCA
AGCTGTTAGCCCTAAACTGGCCATGGCGTGGTTTTTAGAGCAGACCCAGGGCCATGTGCTCGTAGCTCATCATGCACCGT
TAGATCTTTGCTTCTTAAAAGCCGAAATTCAGCGCTGTTACGGTCAGACGATTCAGTTTGTTGCTATCGATACCATGGCT
GTTGAGAAGAGGCGTCTGCTGATGCAGATTGATGTCATCAAAGAGGGGAGTTTAAGGCTCGATGCCTGTCGTCAACGCTA
TGGGCTACCTGTTTACGCAGCGCATAATGCGGCTATAGATGCGCTTGCCTGTGGAGAATTATTGCTGGCGCAGATAGCAG
CAATTGCGGGAAACGATGAATTAAGTTTATTTGACTTATTAAATTAA

Upstream 100 bases:

>100_bases
AAGTTGGACTAAAGCTTAAAATGATGCGCAGTTATTAATGGTTAAGAGGTTTATCCATGTAACAAGATTGGGACTATTAA
TTTAGGTTGTTACTTTGAGA

Downstream 100 bases:

>100_bases
CGCTCATCTCATCAGATTACGTAAACCTCTACTTAGCTAACTACTGTCTTATTTACAGACATCATCTCTTAATCATGGTT
TTAGTTACATTTTTAGTATT

Product: exonuclease RNase T and DNA polymerase III

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MENLRNLYLKTRLQFNALLSQDTVISGYHRALVTQISKPLSQLPLMAVDLEMTGLNSQFDQILSIGLIPIRNGLLQVSHS
KHLLVSIDGSVGDSAVIHGIVDNQLTQAVSPKLAMAWFLEQTQGHVLVAHHAPLDLCFLKAEIQRCYGQTIQFVAIDTMA
VEKRRLLMQIDVIKEGSLRLDACRQRYGLPVYAAHNAAIDALACGELLLAQIAAIAGNDELSLFDLLN

Sequences:

>Translated_228_residues
MENLRNLYLKTRLQFNALLSQDTVISGYHRALVTQISKPLSQLPLMAVDLEMTGLNSQFDQILSIGLIPIRNGLLQVSHS
KHLLVSIDGSVGDSAVIHGIVDNQLTQAVSPKLAMAWFLEQTQGHVLVAHHAPLDLCFLKAEIQRCYGQTIQFVAIDTMA
VEKRRLLMQIDVIKEGSLRLDACRQRYGLPVYAAHNAAIDALACGELLLAQIAAIAGNDELSLFDLLN
>Mature_228_residues
MENLRNLYLKTRLQFNALLSQDTVISGYHRALVTQISKPLSQLPLMAVDLEMTGLNSQFDQILSIGLIPIRNGLLQVSHS
KHLLVSIDGSVGDSAVIHGIVDNQLTQAVSPKLAMAWFLEQTQGHVLVAHHAPLDLCFLKAEIQRCYGQTIQFVAIDTMA
VEKRRLLMQIDVIKEGSLRLDACRQRYGLPVYAAHNAAIDALACGELLLAQIAAIAGNDELSLFDLLN

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25092; Mature: 25092

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLRNLYLKTRLQFNALLSQDTVISGYHRALVTQISKPLSQLPLMAVDLEMTGLNSQFD
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHH
QILSIGLIPIRNGLLQVSHSKHLLVSIDGSVGDSAVIHGIVDNQLTQAVSPKLAMAWFLE
HHHHHCCHHHCCCEEEECCCCEEEEEECCCCCCHHHEEHHHHHHHHHHHCCHHHHHHHHH
QTQGHVLVAHHAPLDLCFLKAEIQRCYGQTIQFVAIDTMAVEKRRLLMQIDVIKEGSLRL
HCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHEEEEEECCCCEEH
DACRQRYGLPVYAAHNAAIDALACGELLLAQIAAIAGNDELSLFDLLN
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEHEECCC
>Mature Secondary Structure
MENLRNLYLKTRLQFNALLSQDTVISGYHRALVTQISKPLSQLPLMAVDLEMTGLNSQFD
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHH
QILSIGLIPIRNGLLQVSHSKHLLVSIDGSVGDSAVIHGIVDNQLTQAVSPKLAMAWFLE
HHHHHCCHHHCCCEEEECCCCEEEEEECCCCCCHHHEEHHHHHHHHHHHCCHHHHHHHHH
QTQGHVLVAHHAPLDLCFLKAEIQRCYGQTIQFVAIDTMAVEKRRLLMQIDVIKEGSLRL
HCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHEEEEEECCCCEEH
DACRQRYGLPVYAAHNAAIDALACGELLLAQIAAIAGNDELSLFDLLN
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]