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The map label for this gene is ycbL [H]

Identifier: 157961461

GI number: 157961461

Start: 1980710

End: 1981354

Strand: Direct

Name: ycbL [H]

Synonym: Spea_1635

Alternate gene names: 157961461

Gene position: 1980710-1981354 (Clockwise)

Preceding gene: 157961458

Following gene: 157961462

Centisome position: 38.28

GC content: 46.36

Gene sequence:

>645_bases
ATGAAGTATCAGTTAATACCCGTCACCCCATTTCAGCAAAATTGTAGTTTAATCTGGTGCGACCAAACCATGAAAGCGGC
GGTAGTCGACCCAGGTGGTAATATCGAGCGTATTCTAGAAGAAGCAGCCAAAAATAAGGTGGTGGTGGAAAAAGTATTAC
TGACTCACGGCCATATAGATCATGTTGGCGCGGCGAAATCATTAGCCGAACAACTCAATGTGCCCATTATTGGTCCTCAT
AAAGCCGATGAATACTGGCTAGATAGCTTACCGAAACAGAGTCAGCATTTTGGTTTTGTGCATTGTGACGCTTTTGCGCC
AACGCAATATCTCGAAGATGGCGACGACGTCACTGTAGGTAATCAAGTCTTGAAGGTACTGCATTGCCCAGGTCATACAC
CCGGCCACGTGGTGTTTTTTGCCCAATCGGCAAAGTTAGCCTGGGTCGGTGATGTGCTGTTCAGAGGCTCCATCGGTCGA
ACAGATTTCCCGTTATCGAATCATCAAGATTTGATTGATTCGATCACCCAAAAACTGTGGTCATTAGGCAGTGACGTCCA
GTTTATTCCTGGTCACGGTCCACTATCGACTTTTGGCGATGAGCGAGTACAAAACCCCTTTGTAGCCGATCAATTATTCA
GCTAG

Upstream 100 bases:

>100_bases
GCGTTAGATCAAATTATCCTAATTATAGATAGTCGAAGCGGCCAACATGGCGTAATCTTTATCCATTCACAGCGAAACAT
AGAGCCTTAGGTGATTTTCG

Downstream 100 bases:

>100_bases
TCGCGAGTTGAGTCGCTTAATTTTGGCTTGTTGTAAAAAAATCGCGTAACAAAGTTTTGAAACGCTAAATACCGTTAACA
GCCCCTCGTAAAGCGAGGGG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKYQLIPVTPFQQNCSLIWCDQTMKAAVVDPGGNIERILEEAAKNKVVVEKVLLTHGHIDHVGAAKSLAEQLNVPIIGPH
KADEYWLDSLPKQSQHFGFVHCDAFAPTQYLEDGDDVTVGNQVLKVLHCPGHTPGHVVFFAQSAKLAWVGDVLFRGSIGR
TDFPLSNHQDLIDSITQKLWSLGSDVQFIPGHGPLSTFGDERVQNPFVADQLFS

Sequences:

>Translated_214_residues
MKYQLIPVTPFQQNCSLIWCDQTMKAAVVDPGGNIERILEEAAKNKVVVEKVLLTHGHIDHVGAAKSLAEQLNVPIIGPH
KADEYWLDSLPKQSQHFGFVHCDAFAPTQYLEDGDDVTVGNQVLKVLHCPGHTPGHVVFFAQSAKLAWVGDVLFRGSIGR
TDFPLSNHQDLIDSITQKLWSLGSDVQFIPGHGPLSTFGDERVQNPFVADQLFS
>Mature_214_residues
MKYQLIPVTPFQQNCSLIWCDQTMKAAVVDPGGNIERILEEAAKNKVVVEKVLLTHGHIDHVGAAKSLAEQLNVPIIGPH
KADEYWLDSLPKQSQHFGFVHCDAFAPTQYLEDGDDVTVGNQVLKVLHCPGHTPGHVVFFAQSAKLAWVGDVLFRGSIGR
TDFPLSNHQDLIDSITQKLWSLGSDVQFIPGHGPLSTFGDERVQNPFVADQLFS

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=101, Percent_Identity=35.6435643564356, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=56.6037735849057, Blast_Score=265, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23604; Mature: 23604

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQLIPVTPFQQNCSLIWCDQTMKAAVVDPGGNIERILEEAAKNKVVVEKVLLTHGHID
CCEEEEECCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCH
HVGAAKSLAEQLNVPIIGPHKADEYWLDSLPKQSQHFGFVHCDAFAPTQYLEDGDDVTVG
HHHHHHHHHHHCCCCEECCCCCCHHHHHCCCCCCCCCCEEEECCCCCHHHHCCCCCEEHH
NQVLKVLHCPGHTPGHVVFFAQSAKLAWVGDVLFRGSIGRTDFPLSNHQDLIDSITQKLW
HHHHHHHCCCCCCCCEEEEEECCCCEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
SLGSDVQFIPGHGPLSTFGDERVQNPFVADQLFS
HCCCCCEEECCCCCCCCCCHHHHCCCCHHHHHCC
>Mature Secondary Structure
MKYQLIPVTPFQQNCSLIWCDQTMKAAVVDPGGNIERILEEAAKNKVVVEKVLLTHGHID
CCEEEEECCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCH
HVGAAKSLAEQLNVPIIGPHKADEYWLDSLPKQSQHFGFVHCDAFAPTQYLEDGDDVTVG
HHHHHHHHHHHCCCCEECCCCCCHHHHHCCCCCCCCCCEEEECCCCCHHHHCCCCCEEHH
NQVLKVLHCPGHTPGHVVFFAQSAKLAWVGDVLFRGSIGRTDFPLSNHQDLIDSITQKLW
HHHHHHHCCCCCCCCEEEEEECCCCEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
SLGSDVQFIPGHGPLSTFGDERVQNPFVADQLFS
HCCCCCEEECCCCCCCCCCHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]