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The map label for this gene is melR [H]

Identifier: 157961452

GI number: 157961452

Start: 1967581

End: 1968459

Strand: Direct

Name: melR [H]

Synonym: Spea_1626

Alternate gene names: 157961452

Gene position: 1967581-1968459 (Clockwise)

Preceding gene: 157961451

Following gene: 157961453

Centisome position: 38.02

GC content: 44.82

Gene sequence:

>879_bases
ATGTTTGAATGGGTTGAGAAGATCTCCTTTAACGAAGCCAGTCCATTAGCAGTGCAAGCTCAAGATACTCAATTTGGCTT
ACATCGTAAAAAACCCGCTGTAATGCCCCATAGTCATTGGCATGGCCATATAGAGATCAATTACCTGTTTGATTGCTCAG
CCGATTATCTGATTAATGGCCAAGAGATCACTGTGCCTGAGGGGCGGATGATCATCTTTTGGGCCTCTTTCCCCCATCAA
ATGGTCGCTTCTCGTGGCGACGGCGAGCTAGTCAATATCTATATCCCGTTGCAATCCTTTTTGACATGGATGCTGCCAAG
TAGCTTTGTGAGTCAGTTGCTGCACGGCGAGGTTATCGTGTCTGACAGCTTATATGCTTGCGATAAAGAGCTGACGCAGA
TCTGGGAAACCGATATTAAACGAAATGCCCCTTTACTAACCAGCCAGGTGATTAACGAGATCCGCGGCCGAATTCGACGC
ATGTCGATAGAGGACTACAGCACCTTCGAGCTAGCGAATCGAGTGGCGAAACAGGAAGATAAACCCGTGTTTGGTGGCTT
AAACCATATCCAAACCATGTTGCGTTATATTGCCGACAATTACGATCAAAAAATTACAATTGAAAATGTTTCAACCTCTA
CTGGCTTACATAAAAACTATGCCATGAAGTTGTTTAATCGGGTGATGAAAGTGTCGATTAAGCAATACATTAACCAGCTT
AGGCTACAGCATGCCCAGGCGCTCCTTATCGATACCCAAAGTCCTGTGCTCAATATTGCACTGGAAGCGGGCTTTGGCTC
AGTTAGTCGCTTCTATGATATTTTTCAGCGAGAATTTGGCATGTCGCCACTTGAATTCAGACGAAAAGTAAATTGCTGA

Upstream 100 bases:

>100_bases
TCCTAAATCATCAGCTTGAGTTCTTGTTTAGTAACTTTCAATTGTTTAACAAAGGCCTATGGGGTAGCTTGGTATCTAAA
GCAACTATGGAGTGAGACAG

Downstream 100 bases:

>100_bases
AGTGATTTTCTAGGAAGGCTTTAGGGCTTTCTAGTAAGAGCACTCGTGACGGTTCGTGCTTCAATCAGTTTCAATAAATA
TATTAGTTTTAATAACCTGT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MFEWVEKISFNEASPLAVQAQDTQFGLHRKKPAVMPHSHWHGHIEINYLFDCSADYLINGQEITVPEGRMIIFWASFPHQ
MVASRGDGELVNIYIPLQSFLTWMLPSSFVSQLLHGEVIVSDSLYACDKELTQIWETDIKRNAPLLTSQVINEIRGRIRR
MSIEDYSTFELANRVAKQEDKPVFGGLNHIQTMLRYIADNYDQKITIENVSTSTGLHKNYAMKLFNRVMKVSIKQYINQL
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFGMSPLEFRRKVNC

Sequences:

>Translated_292_residues
MFEWVEKISFNEASPLAVQAQDTQFGLHRKKPAVMPHSHWHGHIEINYLFDCSADYLINGQEITVPEGRMIIFWASFPHQ
MVASRGDGELVNIYIPLQSFLTWMLPSSFVSQLLHGEVIVSDSLYACDKELTQIWETDIKRNAPLLTSQVINEIRGRIRR
MSIEDYSTFELANRVAKQEDKPVFGGLNHIQTMLRYIADNYDQKITIENVSTSTGLHKNYAMKLFNRVMKVSIKQYINQL
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFGMSPLEFRRKVNC
>Mature_292_residues
MFEWVEKISFNEASPLAVQAQDTQFGLHRKKPAVMPHSHWHGHIEINYLFDCSADYLINGQEITVPEGRMIIFWASFPHQ
MVASRGDGELVNIYIPLQSFLTWMLPSSFVSQLLHGEVIVSDSLYACDKELTQIWETDIKRNAPLLTSQVINEIRGRIRR
MSIEDYSTFELANRVAKQEDKPVFGGLNHIQTMLRYIADNYDQKITIENVSTSTGLHKNYAMKLFNRVMKVSIKQYINQL
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFGMSPLEFRRKVNC

Specific function: Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790559, Length=276, Percent_Identity=34.0579710144928, Blast_Score=188, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008917
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33692; Mature: 33692

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEWVEKISFNEASPLAVQAQDTQFGLHRKKPAVMPHSHWHGHIEINYLFDCSADYLING
CCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECC
QEITVPEGRMIIFWASFPHQMVASRGDGELVNIYIPLQSFLTWMLPSSFVSQLLHGEVIV
CEEECCCCCEEEEEECCCHHHHHCCCCCCEEEEEEEHHHHHHHHCCHHHHHHHHCCCEEE
SDSLYACDKELTQIWETDIKRNAPLLTSQVINEIRGRIRRMSIEDYSTFELANRVAKQED
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
KPVFGGLNHIQTMLRYIADNYDQKITIENVSTSTGLHKNYAMKLFNRVMKVSIKQYINQL
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFGMSPLEFRRKVNC
HHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure
MFEWVEKISFNEASPLAVQAQDTQFGLHRKKPAVMPHSHWHGHIEINYLFDCSADYLING
CCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECC
QEITVPEGRMIIFWASFPHQMVASRGDGELVNIYIPLQSFLTWMLPSSFVSQLLHGEVIV
CEEECCCCCEEEEEECCCHHHHHCCCCCCEEEEEEEHHHHHHHHCCHHHHHHHHCCCEEE
SDSLYACDKELTQIWETDIKRNAPLLTSQVINEIRGRIRRMSIEDYSTFELANRVAKQED
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
KPVFGGLNHIQTMLRYIADNYDQKITIENVSTSTGLHKNYAMKLFNRVMKVSIKQYINQL
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLQHAQALLIDTQSPVLNIALEAGFGSVSRFYDIFQREFGMSPLEFRRKVNC
HHHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]