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The map label for this gene is trpB [H]

Identifier: 157961412

GI number: 157961412

Start: 1924162

End: 1925391

Strand: Reverse

Name: trpB [H]

Synonym: Spea_1586

Alternate gene names: 157961412

Gene position: 1925391-1924162 (Counterclockwise)

Preceding gene: 157961413

Following gene: 157961411

Centisome position: 37.21

GC content: 48.62

Gene sequence:

>1230_bases
ATGAGCAAGTTAAACCCATACTTTGGGGAATACGGTGGTATGTACGTACCGCAAATTTTAATGCCAGCGCTTAAGCAACT
AGAAACCGCTTTTATTGAAGCCCAAGAAGACGAGAGCTTTCAGCAGGAGTTTACCGAGCTTTTAAAGAACTATGCCGGTC
GTCCAACGGCGTTGACCTTAACGCGCAACTTAAGCCCTAATCCGCTGACTAAGATCTATCTAAAACGTGAAGATTTGCTA
CACGGCGGCGCCCACAAGACTAACCAAGTATTAGGTCAGGCATTACTGGCTAAACGTATGGGTAAAAAAGAGATCATCGC
TGAAACTGGCGCGGGTCAACACGGTGTGGCAACAGCCCTTGCCTGCGCATTGCTAGGCCTTAAGTGTAAGGTGTATATGG
GCGCGAAAGACGTTGAACGTCAATCACCAAACGTATTTAGAATGAAGCTAATGGGCGCAGAAGTTATCCCAGTGACCTCT
GGCTCGGCCACTTTGAAAGATGCCTGTAACGAAGCGATGCGTGACTGGTCTGGTAGTTATGATAAAGCCCACTACCTACT
GGGCACTGCAGCAGGTCCGCACCCATTCCCAACAATTGTACGTGAATTCCAACGTATGATTGGCGAAGAAACTAAGAGTC
AAATTCTTGAGCGTGAAGGCCGCCTACCTGATGCGGTTATTGCCTGTGTCGGCGGTGGTTCTAACGCGATTGGTATGTTT
GCCGACTTTATTGACGAAGAAGAGGTGGCACTAATTGGTGTTGAGCCTGCAGGAAAAGGCATCGATACTCCAATGCACGG
CGCGCCACTAAAGCATGGTAAAACTGGTATTTTCTTTGGTATGAAAGCGCCACTTATGCAAGACAGCGAAGGGCAAATTG
AAGAGTCTTACTCTGTATCCGCCGGTCTGGATTTCCCATCTGTTGGGCCGCAGCATGCACACCTTGCCGCAACCGGCCGC
GCAACTTACGAGTCAGCCACCGATGATGAAGCGTTAGAAGCTTTCCAATTACTGGCACGATCAGAAGGGATCATCCCCGC
ACTTGAGTCGGCTCACGCCCTAGCTTATGCGGTAAAACTTGCAAAAGAAGCCACCAAAGAGACCATTTTAGTGGTTAACC
TGTCTGGCCGCGGCGACAAAGATATCTTCACGGTTGCGGACATTCTTGAGCAACAAAAAGTTGAGCAACAAGAAGCTGAA
CAGCAACAAACTAACAATCAGAACAACTAG

Upstream 100 bases:

>100_bases
CTGATTTTATTAGCAGCTGTAAAAAGCTAGTTTCTAAACCCTATTATCCCCACATGCAAAATCGGCCTGTGGTAAAAAAT
TAGTCATAAAGGACAAGAAT

Downstream 100 bases:

>100_bases
GAGAGTGGCAATGAGTCAACGTTACCAGGCAGCCTTTGCCGCCCTAAATGAGAAACAGCAAGGCGCATTTGTGCCATTCG
TGACCTTAGGCGATCCATCG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSKLNPYFGEYGGMYVPQILMPALKQLETAFIEAQEDESFQQEFTELLKNYAGRPTALTLTRNLSPNPLTKIYLKREDLL
HGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVERQSPNVFRMKLMGAEVIPVTS
GSATLKDACNEAMRDWSGSYDKAHYLLGTAAGPHPFPTIVREFQRMIGEETKSQILEREGRLPDAVIACVGGGSNAIGMF
ADFIDEEEVALIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYSVSAGLDFPSVGPQHAHLAATGR
ATYESATDDEALEAFQLLARSEGIIPALESAHALAYAVKLAKEATKETILVVNLSGRGDKDIFTVADILEQQKVEQQEAE
QQQTNNQNN

Sequences:

>Translated_409_residues
MSKLNPYFGEYGGMYVPQILMPALKQLETAFIEAQEDESFQQEFTELLKNYAGRPTALTLTRNLSPNPLTKIYLKREDLL
HGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVERQSPNVFRMKLMGAEVIPVTS
GSATLKDACNEAMRDWSGSYDKAHYLLGTAAGPHPFPTIVREFQRMIGEETKSQILEREGRLPDAVIACVGGGSNAIGMF
ADFIDEEEVALIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYSVSAGLDFPSVGPQHAHLAATGR
ATYESATDDEALEAFQLLARSEGIIPALESAHALAYAVKLAKEATKETILVVNLSGRGDKDIFTVADILEQQKVEQQEAE
QQQTNNQNN
>Mature_408_residues
SKLNPYFGEYGGMYVPQILMPALKQLETAFIEAQEDESFQQEFTELLKNYAGRPTALTLTRNLSPNPLTKIYLKREDLLH
GGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVERQSPNVFRMKLMGAEVIPVTSG
SATLKDACNEAMRDWSGSYDKAHYLLGTAAGPHPFPTIVREFQRMIGEETKSQILEREGRLPDAVIACVGGGSNAIGMFA
DFIDEEEVALIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYSVSAGLDFPSVGPQHAHLAATGRA
TYESATDDEALEAFQLLARSEGIIPALESAHALAYAVKLAKEATKETILVVNLSGRGDKDIFTVADILEQQKVEQQEAEQ
QQTNNQNN

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=390, Percent_Identity=79.7435897435898, Blast_Score=651, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=53.3854166666667, Blast_Score=421, Evalue=1e-119,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44266; Mature: 44135

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLNPYFGEYGGMYVPQILMPALKQLETAFIEAQEDESFQQEFTELLKNYAGRPTALTL
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEE
TRNLSPNPLTKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATAL
ECCCCCCCHHEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
ACALLGLKCKVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSATLKDACNEAMRDWSGSY
HHHHHCCCEEEEECCHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCC
DKAHYLLGTAAGPHPFPTIVREFQRMIGEETKSQILEREGRLPDAVIACVGGGSNAIGMF
CCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
ADFIDEEEVALIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYSVS
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHCCCCC
AGLDFPSVGPQHAHLAATGRATYESATDDEALEAFQLLARSEGIIPALESAHALAYAVKL
CCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AKEATKETILVVNLSGRGDKDIFTVADILEQQKVEQQEAEQQQTNNQNN
HHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKLNPYFGEYGGMYVPQILMPALKQLETAFIEAQEDESFQQEFTELLKNYAGRPTALTL
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEE
TRNLSPNPLTKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATAL
ECCCCCCCHHEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
ACALLGLKCKVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSATLKDACNEAMRDWSGSY
HHHHHCCCEEEEECCHHHHHCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCC
DKAHYLLGTAAGPHPFPTIVREFQRMIGEETKSQILEREGRLPDAVIACVGGGSNAIGMF
CCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHH
ADFIDEEEVALIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYSVS
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHCCCCC
AGLDFPSVGPQHAHLAATGRATYESATDDEALEAFQLLARSEGIIPALESAHALAYAVKL
CCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AKEATKETILVVNLSGRGDKDIFTVADILEQQKVEQQEAEQQQTNNQNN
HHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA