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The map label for this gene is yeeO [C]

Identifier: 157961384

GI number: 157961384

Start: 1892573

End: 1894123

Strand: Direct

Name: yeeO [C]

Synonym: Spea_1558

Alternate gene names: 157961384

Gene position: 1892573-1894123 (Clockwise)

Preceding gene: 157961383

Following gene: 157961386

Centisome position: 36.57

GC content: 49.13

Gene sequence:

>1551_bases
ATGGCTGTAGCCAAGTTTGTACAGGGATCGATTCTGCGCCATATTTTTGTGATGAGTTCCACCGCGGCTATCGGTATTTC
GGCGCTGTTTGTGGTCGACTTATTGGATATATTCTTCCTCAGTTTACTGGGGGAGCAGGAGCTTGCCGCGGCAGTTGGCT
ACGCTGGCACCATCTCATTCTTTACCACTTCAATAGGCATCGGCCTCTCTATTGCTCTTGGGGCTTTGGTGTCGCGCTCA
ATTGGCGCTAAAGAGAGTGAAAAGGCTAAGCGATTACTATTAAACAGTCTCGTTGTGACCTTGTTAATGAGCCTGTTTGT
CGCATTTAGCGTGTATATGTTTATTCCAGAGCTGTTGAGACTGGTGGGCGCGACAGGCAGAACCGCCGAGCTTGCCGAGA
GTTATCTTAATATTCTGGTGCCTTCCTTGCCGCTTATCTGTCTAGCGATGGCGCTCGGTAGTGCCTTGAGGGCGGTGGGC
GATGCCAAGTTGTCTATGGTGTCGACCTTAGTCGGTGGTGGCGTAAATGCGGTTTTTGACCCGATATTTATCTTCATGTT
TGCCATGGGAATTGAAGGTGCAGCCGTAGCTTCAGTAATGGCTCGTTTTGCCGTGTTTGCGGTTGCGGCAAGGGGCGTTG
TGGTCAAGCACAACCTATTGGGTCGCTTTAATTTTGATCACTTTGTTGAAGATTTATCTCCTATCTTTGCTATCGCAGGT
CCCGCTATGCTCACTAACGTGGCCACCCCTATCGGTAATGCGGTGGTGACTCGCGCCATCGCAGATTTTGGTGATAGTTA
TGTGGCTGGCTGGGCAGTGCTTGGGCGCCTCATTCCGGTGTCGTTTGGTATGATCTTCGCCTTATCCGGGGCCATCGGGC
CGATTGTTGGCCAGAACTATGGCGCGTTGCAGTTTGAGCGGGTGAAAGAGTCGCTCACCCGAGCGATCCAATTTTGCGCC
GTCTATGTATTGGCTGTGTCGCTGCTATTGTTTTTAACACGCCATCAAATAGTAAGTGTGTTTGATATGAAAGGTGATGC
GGCGGATTTGATCTTGTTCTTCTGCTCGTTTATCGCGGTGTTCTTTATCTTCTCAGGTGTTTTATTCGTCGCCAATGCCT
CATTTAATAACTTAGGCAAGGCCAAGTATTCGACTCTGTTTAATGTGGGTAAGGCAACATTAGGCACCATTCCATTCGTT
TATTTTGGTGCTAAGTGGGGCGGGGTTTACGGCGTGTTGATTGGTCAGGCGGTAGGCTCGATTATTTTCGGTATCGCGGG
TGTGCTTGTGGCGTACCGATTGGTTGAACGGGTTAAGGCGGCAGCTGTTGTAACTGTTGCTGATGACGTCGCTGATTTCG
CGAAGGACACGGCTAAAGATAAGACGAAAGATAAGAGCGAGTTTGATGAGGAGCTAAGCTTGAGTGGTCAAAGTCCACTT
TCTTCCTCTTGTGCCAACATGGCAATAGTCAATGAGGAGCAAGACTGTGTGGGAAGTAATGAAGTAGCTGAGCTTATTGG
CGTTAAAGAGGAGAGTACTCCTAGCAAATAA

Upstream 100 bases:

>100_bases
CCTGAAAGTTGGTCATGAAAATAATGCGCTCTACTGCGATCATTGCGGCAGTGAATTAGAGAGTGAGCTGTAAAAATACA
ATTAAAGGATTAGAGGTGTT

Downstream 100 bases:

>100_bases
GCTCAATCAAACGAGAAACATTGCGCGGGTTTTGCCGATATTTAGTTAGCTGACGCCGCTTTTTCTTCGTTTGCTTCTAC
TGGCGCGTCATTTGTCGCAT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MAVAKFVQGSILRHIFVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISFFTTSIGIGLSIALGALVSRS
IGAKESEKAKRLLLNSLVVTLLMSLFVAFSVYMFIPELLRLVGATGRTAELAESYLNILVPSLPLICLAMALGSALRAVG
DAKLSMVSTLVGGGVNAVFDPIFIFMFAMGIEGAAVASVMARFAVFAVAARGVVVKHNLLGRFNFDHFVEDLSPIFAIAG
PAMLTNVATPIGNAVVTRAIADFGDSYVAGWAVLGRLIPVSFGMIFALSGAIGPIVGQNYGALQFERVKESLTRAIQFCA
VYVLAVSLLLFLTRHQIVSVFDMKGDAADLILFFCSFIAVFFIFSGVLFVANASFNNLGKAKYSTLFNVGKATLGTIPFV
YFGAKWGGVYGVLIGQAVGSIIFGIAGVLVAYRLVERVKAAAVVTVADDVADFAKDTAKDKTKDKSEFDEELSLSGQSPL
SSSCANMAIVNEEQDCVGSNEVAELIGVKEESTPSK

Sequences:

>Translated_516_residues
MAVAKFVQGSILRHIFVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISFFTTSIGIGLSIALGALVSRS
IGAKESEKAKRLLLNSLVVTLLMSLFVAFSVYMFIPELLRLVGATGRTAELAESYLNILVPSLPLICLAMALGSALRAVG
DAKLSMVSTLVGGGVNAVFDPIFIFMFAMGIEGAAVASVMARFAVFAVAARGVVVKHNLLGRFNFDHFVEDLSPIFAIAG
PAMLTNVATPIGNAVVTRAIADFGDSYVAGWAVLGRLIPVSFGMIFALSGAIGPIVGQNYGALQFERVKESLTRAIQFCA
VYVLAVSLLLFLTRHQIVSVFDMKGDAADLILFFCSFIAVFFIFSGVLFVANASFNNLGKAKYSTLFNVGKATLGTIPFV
YFGAKWGGVYGVLIGQAVGSIIFGIAGVLVAYRLVERVKAAAVVTVADDVADFAKDTAKDKTKDKSEFDEELSLSGQSPL
SSSCANMAIVNEEQDCVGSNEVAELIGVKEESTPSK
>Mature_515_residues
AVAKFVQGSILRHIFVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISFFTTSIGIGLSIALGALVSRSI
GAKESEKAKRLLLNSLVVTLLMSLFVAFSVYMFIPELLRLVGATGRTAELAESYLNILVPSLPLICLAMALGSALRAVGD
AKLSMVSTLVGGGVNAVFDPIFIFMFAMGIEGAAVASVMARFAVFAVAARGVVVKHNLLGRFNFDHFVEDLSPIFAIAGP
AMLTNVATPIGNAVVTRAIADFGDSYVAGWAVLGRLIPVSFGMIFALSGAIGPIVGQNYGALQFERVKESLTRAIQFCAV
YVLAVSLLLFLTRHQIVSVFDMKGDAADLILFFCSFIAVFFIFSGVLFVANASFNNLGKAKYSTLFNVGKATLGTIPFVY
FGAKWGGVYGVLIGQAVGSIIFGIAGVLVAYRLVERVKAAAVVTVADDVADFAKDTAKDKTKDKSEFDEELSLSGQSPLS
SSCANMAIVNEEQDCVGSNEVAELIGVKEESTPSK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Homo sapiens, GI22907060, Length=386, Percent_Identity=21.5025906735751, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 54440; Mature: 54309

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAKFVQGSILRHIFVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHH
FTTSIGIGLSIALGALVSRSIGAKESEKAKRLLLNSLVVTLLMSLFVAFSVYMFIPELLR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGATGRTAELAESYLNILVPSLPLICLAMALGSALRAVGDAKLSMVSTLVGGGVNAVFD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PIFIFMFAMGIEGAAVASVMARFAVFAVAARGVVVKHNLLGRFNFDHFVEDLSPIFAIAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHHHHHHHH
PAMLTNVATPIGNAVVTRAIADFGDSYVAGWAVLGRLIPVSFGMIFALSGAIGPIVGQNY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GALQFERVKESLTRAIQFCAVYVLAVSLLLFLTRHQIVSVFDMKGDAADLILFFCSFIAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FFIFSGVLFVANASFNNLGKAKYSTLFNVGKATLGTIPFVYFGAKWGGVYGVLIGQAVGS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHH
IIFGIAGVLVAYRLVERVKAAAVVTVADDVADFAKDTAKDKTKDKSEFDEELSLSGQSPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
SSSCANMAIVNEEQDCVGSNEVAELIGVKEESTPSK
HHHHCCCEEECCCHHCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AVAKFVQGSILRHIFVMSSTAAIGISALFVVDLLDIFFLSLLGEQELAAAVGYAGTISF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHH
FTTSIGIGLSIALGALVSRSIGAKESEKAKRLLLNSLVVTLLMSLFVAFSVYMFIPELLR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGATGRTAELAESYLNILVPSLPLICLAMALGSALRAVGDAKLSMVSTLVGGGVNAVFD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PIFIFMFAMGIEGAAVASVMARFAVFAVAARGVVVKHNLLGRFNFDHFVEDLSPIFAIAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHHHHHHHH
PAMLTNVATPIGNAVVTRAIADFGDSYVAGWAVLGRLIPVSFGMIFALSGAIGPIVGQNY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GALQFERVKESLTRAIQFCAVYVLAVSLLLFLTRHQIVSVFDMKGDAADLILFFCSFIAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FFIFSGVLFVANASFNNLGKAKYSTLFNVGKATLGTIPFVYFGAKWGGVYGVLIGQAVGS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHH
IIFGIAGVLVAYRLVERVKAAAVVTVADDVADFAKDTAKDKTKDKSEFDEELSLSGQSPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
SSSCANMAIVNEEQDCVGSNEVAELIGVKEESTPSK
HHHHCCCEEECCCHHCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]