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The map label for this gene is htpG [H]

Identifier: 157961352

GI number: 157961352

Start: 1854069

End: 1855985

Strand: Direct

Name: htpG [H]

Synonym: Spea_1526

Alternate gene names: 157961352

Gene position: 1854069-1855985 (Clockwise)

Preceding gene: 157961351

Following gene: 157961353

Centisome position: 35.83

GC content: 45.7

Gene sequence:

>1917_bases
ATGTCACAACAAGAGACTCATGGCTTTCAAACTGAAGTCAAACAACTACTACATTTGATGATCCACTCTCTGTACTCAAA
CAAAGAGATCTTTTTGCGTGAGTTAGTATCGAATGCTGCCGATGCCGCCGATAAACTACGCTATGAAGCCCTAACAAACG
ATAACCTTTATGAAGGTGACGGCGAGCTACGTGTTCGCATTAGTGCAGATAAAGAGAAAGGTACCGTAACTATTGAAGAT
AATGGTATCGGTATGACTCGCGACGGTGTGATTGAACACTTAGGGACAATCGCTAAATCGGGCACTGCTGATTTCTTCAA
GAAGCTTTCTGGTGATGAGTCAAAAGACTCACAATTGATTGGTCAGTTCGGTGTCGGTTTCTACTCTTCATTTATTGTTG
CAGACAGAGTGACTGTTCGCACCCGTGCTGCTGGCCATAGCGCCGATGAAGCGGTACTTTGGGAGTCAGCCGGTGAAGGT
GACTTCACTGTTGAGACCATTTCTAAGCAAACTCGTGGTACAGAAATTACCCTACATCTTCGTGATGATGAAAAAGAGTT
TGCAGACGACTATCGTCTACGCTCAATCATCACTAAGTATTCAGATCATATCTCAGTACCTGTAGAGATGTTTGAAGCTG
GAACGCCAGCAGTTGAAGCCACTGAAGATACAGAAGCTGTAGCTGCTACTGAAGGTAGCTGGAAGCCAATGAACAAGGCG
ACAGCGCTTTGGACTCGTAACAAAAGTGATGTGTCTGATGAAGAGTATCAAGAGTTTTACAAGCATATCTCTCATGACTT
TACTGACCCACTACTATGGAGCCACAACCGCGTAGAAGGTAAGCAAGAGTATACTAGCCTGCTTTATATCCCAGCTAAAG
CACCTTGGGATATGTGGAACCGTGACCGCAAGCATGGCTTAAAACTATTCGTTCAGCGTGTATTCGTGATGGACGATGCC
GAGCAGTTTATGCCGAGCTACCTGCGTTTTGTGCAAGGTCTAATCGACTCGAACGACCTGCCGCTAAACGTATCTCGTGA
AATCCTGCAAGATAACAAGGTGACAACGGCACTGCGAACCGCTGTGACTAAGCGTGTATTGGGTATGCTTGAAAAGCTAG
CTAAGAATGACGCTGAAAAGTACCAGTCTTTCTGGACTGAATTTGGTCAAGTTCTGAAAGAAGGTCCTGCTGAAGACTTC
GCTAACAAAGAGCGCATTGCAGGTCTATTGCGTTTTGCATCGACTCATACAGGTGAGGCGACGCCGAATGTTTCACTAGC
TGATTATATCGAGCGCATGCAAGAAGGTCAGTCTAAGATCTACTACATCGTTGCCGATAGCCATGAAGCTGCAGCCAATA
GCCCACATCTTGAATTGCTACGTAAGAAAGGCATTGAAGTATTATTGATGTCTGAGCGCATCGATGAGTGGTTGATTAAC
CACTTAACTGAGTTCGATGGCAAGAAGCTGCACTCGGTAACTCGCGGTGATCTTGAGCTAGGTGAGCTTGAAGATGATGA
TGAAAAAGAGGCGCAAGAGAAGTTACAAACTGAATCTGAAGGCCTAGTTAAGCGCGTTAAAGACAGCTTAGGCGACAAAG
TTTCAGAGGTTAAGGTGACGACGCGTCTAACAGATACGCCTGCTTGTGTGGTTGCAGGTGAAGGCGAGATGTCGACCCAG
ATGATCAAGTTGATGCAAGCAGCAGGACAAGACGTACCTGAGCCTAAGCCGACATTTGAGCTAAACCCTGAACACCCATT
GGTTGCCCGTTTAAATGACGAGCAAGATGAGCAGCAATTTGCTCAATGGTCAGAGCTATTACTACAGCAAGCATTGTTGT
CAGAGAAAGGCAGCCTCGCAGACCCATCTGCATTCATTAAGCTGATGAACCAAATGCTATTAGCTAGCGTTAAGTAA

Upstream 100 bases:

>100_bases
AATTGAAGGCAATGCACTCTTTATCCCTTGAAAAGCATTTTTCTAGCCCCATCTCTTAAGCAAGCGTTACTTAAACTGAT
TTTTTTAAAGGGAACATTTC

Downstream 100 bases:

>100_bases
TCAACAACTATGATTAAAGGGGCAGTTATACTGATTGGTATTACTGCCTCTTTCTTTATGGTCACTCGCTAAAAGCGAAG
GAAAAGTTATGCAATCGATT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDNLYEGDGELRVRISADKEKGTVTIED
NGIGMTRDGVIEHLGTIAKSGTADFFKKLSGDESKDSQLIGQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEG
DFTVETISKQTRGTEITLHLRDDEKEFADDYRLRSIITKYSDHISVPVEMFEAGTPAVEATEDTEAVAATEGSWKPMNKA
TALWTRNKSDVSDEEYQEFYKHISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMWNRDRKHGLKLFVQRVFVMDDA
EQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRTAVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAEDF
ANKERIAGLLRFASTHTGEATPNVSLADYIERMQEGQSKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLIN
HLTEFDGKKLHSVTRGDLELGELEDDDEKEAQEKLQTESEGLVKRVKDSLGDKVSEVKVTTRLTDTPACVVAGEGEMSTQ
MIKLMQAAGQDVPEPKPTFELNPEHPLVARLNDEQDEQQFAQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK

Sequences:

>Translated_638_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDNLYEGDGELRVRISADKEKGTVTIED
NGIGMTRDGVIEHLGTIAKSGTADFFKKLSGDESKDSQLIGQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEG
DFTVETISKQTRGTEITLHLRDDEKEFADDYRLRSIITKYSDHISVPVEMFEAGTPAVEATEDTEAVAATEGSWKPMNKA
TALWTRNKSDVSDEEYQEFYKHISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMWNRDRKHGLKLFVQRVFVMDDA
EQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRTAVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAEDF
ANKERIAGLLRFASTHTGEATPNVSLADYIERMQEGQSKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLIN
HLTEFDGKKLHSVTRGDLELGELEDDDEKEAQEKLQTESEGLVKRVKDSLGDKVSEVKVTTRLTDTPACVVAGEGEMSTQ
MIKLMQAAGQDVPEPKPTFELNPEHPLVARLNDEQDEQQFAQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK
>Mature_637_residues
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDNLYEGDGELRVRISADKEKGTVTIEDN
GIGMTRDGVIEHLGTIAKSGTADFFKKLSGDESKDSQLIGQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEGD
FTVETISKQTRGTEITLHLRDDEKEFADDYRLRSIITKYSDHISVPVEMFEAGTPAVEATEDTEAVAATEGSWKPMNKAT
ALWTRNKSDVSDEEYQEFYKHISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMWNRDRKHGLKLFVQRVFVMDDAE
QFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRTAVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAEDFA
NKERIAGLLRFASTHTGEATPNVSLADYIERMQEGQSKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
LTEFDGKKLHSVTRGDLELGELEDDDEKEAQEKLQTESEGLVKRVKDSLGDKVSEVKVTTRLTDTPACVVAGEGEMSTQM
IKLMQAAGQDVPEPKPTFELNPEHPLVARLNDEQDEQQFAQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=686, Percent_Identity=37.3177842565598, Blast_Score=434, Evalue=1e-121,
Organism=Homo sapiens, GI155722983, Length=645, Percent_Identity=34.7286821705426, Blast_Score=378, Evalue=1e-104,
Organism=Homo sapiens, GI154146191, Length=408, Percent_Identity=38.9705882352941, Blast_Score=279, Evalue=8e-75,
Organism=Homo sapiens, GI153792590, Length=408, Percent_Identity=38.9705882352941, Blast_Score=276, Evalue=5e-74,
Organism=Homo sapiens, GI20149594, Length=408, Percent_Identity=38.2352941176471, Blast_Score=273, Evalue=4e-73,
Organism=Escherichia coli, GI1786679, Length=635, Percent_Identity=68.0314960629921, Blast_Score=892, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=37.125748502994, Blast_Score=449, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17542208, Length=684, Percent_Identity=37.1345029239766, Blast_Score=409, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI115535205, Length=654, Percent_Identity=33.6391437308869, Blast_Score=332, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI115535167, Length=443, Percent_Identity=35.665914221219, Blast_Score=265, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6323840, Length=676, Percent_Identity=38.3136094674556, Blast_Score=460, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325016, Length=409, Percent_Identity=38.8753056234719, Blast_Score=296, Evalue=8e-81,
Organism=Drosophila melanogaster, GI17647529, Length=695, Percent_Identity=36.9784172661871, Blast_Score=465, Evalue=1e-131,
Organism=Drosophila melanogaster, GI21357739, Length=677, Percent_Identity=39.1432791728213, Blast_Score=433, Evalue=1e-121,
Organism=Drosophila melanogaster, GI24586016, Length=653, Percent_Identity=34.3032159264931, Blast_Score=370, Evalue=1e-102,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71882; Mature: 71751

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDNLYEGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
GELRVRISADKEKGTVTIEDNGIGMTRDGVIEHLGTIAKSGTADFFKKLSGDESKDSQLI
CCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHH
GQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEGDFTVETISKQTRGTEITLHL
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEECCCCCCCEEHHHHHHHCCCCEEEEEE
RDDEKEFADDYRLRSIITKYSDHISVPVEMFEAGTPAVEATEDTEAVAATEGSWKPMNKA
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHEECCCCCCCCCHH
TALWTRNKSDVSDEEYQEFYKHISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMWN
HHEEECCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHCEEEEECCCCCHHHHC
RDRKHGLKLFVQRVFVMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRT
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHH
AVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAEDFANKERIAGLLRFASTHTGEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCCC
TPNVSLADYIERMQEGQSKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLIN
CCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHH
HLTEFDGKKLHSVTRGDLELGELEDDDEKEAQEKLQTESEGLVKRVKDSLGDKVSEVKVT
HHHHCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEE
TRLTDTPACVVAGEGEMSTQMIKLMQAAGQDVPEPKPTFELNPEHPLVARLNDEQDEQQF
EEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCEEEECCCCHHHHHH
AQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYEALTNDNLYEGD
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
GELRVRISADKEKGTVTIEDNGIGMTRDGVIEHLGTIAKSGTADFFKKLSGDESKDSQLI
CCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHH
GQFGVGFYSSFIVADRVTVRTRAAGHSADEAVLWESAGEGDFTVETISKQTRGTEITLHL
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEECCCCCCCEEHHHHHHHCCCCEEEEEE
RDDEKEFADDYRLRSIITKYSDHISVPVEMFEAGTPAVEATEDTEAVAATEGSWKPMNKA
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHEECCCCCCCCCHH
TALWTRNKSDVSDEEYQEFYKHISHDFTDPLLWSHNRVEGKQEYTSLLYIPAKAPWDMWN
HHEEECCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHCEEEEECCCCCHHHHC
RDRKHGLKLFVQRVFVMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRT
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHH
AVTKRVLGMLEKLAKNDAEKYQSFWTEFGQVLKEGPAEDFANKERIAGLLRFASTHTGEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCCC
TPNVSLADYIERMQEGQSKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLIN
CCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHH
HLTEFDGKKLHSVTRGDLELGELEDDDEKEAQEKLQTESEGLVKRVKDSLGDKVSEVKVT
HHHHCCCHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEE
TRLTDTPACVVAGEGEMSTQMIKLMQAAGQDVPEPKPTFELNPEHPLVARLNDEQDEQQF
EEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCEEEECCCCHHHHHH
AQWSELLLQQALLSEKGSLADPSAFIKLMNQMLLASVK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA