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The map label for this gene is galE [H]

Identifier: 157961272

GI number: 157961272

Start: 1759867

End: 1760886

Strand: Reverse

Name: galE [H]

Synonym: Spea_1446

Alternate gene names: 157961272

Gene position: 1760886-1759867 (Counterclockwise)

Preceding gene: 157961273

Following gene: 157961271

Centisome position: 34.03

GC content: 45.69

Gene sequence:

>1020_bases
ATGACGATTTTAGTTACCGGCGGCGCTGGTTATATCGGAACCCATACCGTTGTTGAGCTGCTTAATAACGGCAATAACGT
CGTTATCTTAGATAACCTCAGCAACTCAAGTGTTACGGCCTTAGAAAGAGTCGAACAGATCACAGGCAAAAGGGTTACCT
TTTATCAAGGCGATGTACTCAATAGAGCTTTCTTGCAGAAGCTATTTACAGATCATGATATTAAATCAGTCATTCACTTC
GCAGGCCTAAAGGCTGTCGGTGAGTCTGTAGCGCAGCCGCTACGTTACTATGAAAATAACGTCACTGGCACCATCGTCTT
ATGTGAAGTCATGGCTGAATTTAACGTTAAGAACTTAGTCTTTAGCTCATCAGCCACCGTCTATGGTGATCCTGCGAGCC
TACCTATCACAGAAGACTTTCCTACAGGGGCAACCAACCCCTACGGTCAGTCTAAACTAATGGTAGAGCATATACTTGCC
GACCTTTATCACTCAGACAACAGCTGGAATATCGCCCGATTAAGATACTTTAACCCTGTAGGGGCTCATAAGAGCGGCCT
AATCGGTGAAGATCCCAATGATATTCCGAATAACCTGATGCCTTTCATTACTCAGGTTGCCGTTGGTAAACGTGAGCAAT
TAAGTGTGTTTGGCAGTGATTATGATACGGTCGATGGTACGGGAGTACGCGATTACATCCATGTGGTCGATCTCGCTATC
GGTCACTTGCGAGCTCTTGATAAGCTACACACCCAATCAGGCTTGGTGACCTATAACTTAGGTACAGGCCAAGGTTACAG
CGTACTTGAGATGGTTAAAGCCTTTGAAAAAGCCAGCGGCACCACTATTAAATATCAGTTAGTTGAACGCAGACCTGGCG
ACATAGCAGCATGCTACGCAAACCCAGAGAAAGCGCAGAAAGAGTTAAACTGGCAAGCGACTCACAGCATAGATGATATG
GCGCAAAGCAGCTGGCACTGGCAATCAAGTAACCCAAATGGTTACCAGAGCGAAGTCTAA

Upstream 100 bases:

>100_bases
TTAAGACACTTAAGTAATAGACACTTAGTAATAGACACTTAACTAATCGACAATAGCGACAGCCTGTTGAACATCTGCCA
AGATTAAAGGATTTAAAAAA

Downstream 100 bases:

>100_bases
AATCTTAGGACCTAGGTCCTAGGAAAAGCAGATCCTAGGTAAAGCAAAGACGGTTAAATCTGAGACGAAAGCGCCAAGAA
AAGTAAGAATCAAAGGCAAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTILVTGGAGYIGTHTVVELLNNGNNVVILDNLSNSSVTALERVEQITGKRVTFYQGDVLNRAFLQKLFTDHDIKSVIHF
AGLKAVGESVAQPLRYYENNVTGTIVLCEVMAEFNVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILA
DLYHSDNSWNIARLRYFNPVGAHKSGLIGEDPNDIPNNLMPFITQVAVGKREQLSVFGSDYDTVDGTGVRDYIHVVDLAI
GHLRALDKLHTQSGLVTYNLGTGQGYSVLEMVKAFEKASGTTIKYQLVERRPGDIAACYANPEKAQKELNWQATHSIDDM
AQSSWHWQSSNPNGYQSEV

Sequences:

>Translated_339_residues
MTILVTGGAGYIGTHTVVELLNNGNNVVILDNLSNSSVTALERVEQITGKRVTFYQGDVLNRAFLQKLFTDHDIKSVIHF
AGLKAVGESVAQPLRYYENNVTGTIVLCEVMAEFNVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILA
DLYHSDNSWNIARLRYFNPVGAHKSGLIGEDPNDIPNNLMPFITQVAVGKREQLSVFGSDYDTVDGTGVRDYIHVVDLAI
GHLRALDKLHTQSGLVTYNLGTGQGYSVLEMVKAFEKASGTTIKYQLVERRPGDIAACYANPEKAQKELNWQATHSIDDM
AQSSWHWQSSNPNGYQSEV
>Mature_338_residues
TILVTGGAGYIGTHTVVELLNNGNNVVILDNLSNSSVTALERVEQITGKRVTFYQGDVLNRAFLQKLFTDHDIKSVIHFA
GLKAVGESVAQPLRYYENNVTGTIVLCEVMAEFNVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILAD
LYHSDNSWNIARLRYFNPVGAHKSGLIGEDPNDIPNNLMPFITQVAVGKREQLSVFGSDYDTVDGTGVRDYIHVVDLAIG
HLRALDKLHTQSGLVTYNLGTGQGYSVLEMVKAFEKASGTTIKYQLVERRPGDIAACYANPEKAQKELNWQATHSIDDMA
QSSWHWQSSNPNGYQSEV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=58.8921282798834, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=58.8921282798834, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=58.8921282798834, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI7657641, Length=273, Percent_Identity=28.2051282051282, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI42516563, Length=331, Percent_Identity=24.773413897281, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=58.3333333333333, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI48994969, Length=372, Percent_Identity=28.2258064516129, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=25.3443526170799, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71982038, Length=349, Percent_Identity=53.5816618911175, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71982035, Length=347, Percent_Identity=53.0259365994236, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17568069, Length=336, Percent_Identity=24.702380952381, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=54.8104956268222, Blast_Score=387, Evalue=1e-108,
Organism=Drosophila melanogaster, GI19923002, Length=346, Percent_Identity=59.5375722543353, Blast_Score=425, Evalue=1e-119,
Organism=Drosophila melanogaster, GI21356223, Length=324, Percent_Identity=25.6172839506173, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37260; Mature: 37129

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVTGGAGYIGTHTVVELLNNGNNVVILDNLSNSSVTALERVEQITGKRVTFYQGDVL
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHH
NRAFLQKLFTDHDIKSVIHFAGLKAVGESVAQPLRYYENNVTGTIVLCEVMAEFNVKNLV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCHHHEE
FSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILADLYHSDNSWNIARLRYFNPV
EECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GAHKSGLIGEDPNDIPNNLMPFITQVAVGKREQLSVFGSDYDTVDGTGVRDYIHVVDLAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCHHHHHHHHHHHH
GHLRALDKLHTQSGLVTYNLGTGQGYSVLEMVKAFEKASGTTIKYQLVERRPGDIAACYA
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEC
NPEKAQKELNWQATHSIDDMAQSSWHWQSSNPNGYQSEV
CHHHHHHHCCCHHHCCHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TILVTGGAGYIGTHTVVELLNNGNNVVILDNLSNSSVTALERVEQITGKRVTFYQGDVL
EEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHH
NRAFLQKLFTDHDIKSVIHFAGLKAVGESVAQPLRYYENNVTGTIVLCEVMAEFNVKNLV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCHHHEE
FSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILADLYHSDNSWNIARLRYFNPV
EECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GAHKSGLIGEDPNDIPNNLMPFITQVAVGKREQLSVFGSDYDTVDGTGVRDYIHVVDLAI
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCHHHHHHHHHHHH
GHLRALDKLHTQSGLVTYNLGTGQGYSVLEMVKAFEKASGTTIKYQLVERRPGDIAACYA
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEC
NPEKAQKELNWQATHSIDDMAQSSWHWQSSNPNGYQSEV
CHHHHHHHCCCHHHCCHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]