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The map label for this gene is eryC1 [H]

Identifier: 157961230

GI number: 157961230

Start: 1703001

End: 1704116

Strand: Direct

Name: eryC1 [H]

Synonym: Spea_1403

Alternate gene names: 157961230

Gene position: 1703001-1704116 (Clockwise)

Preceding gene: 157961229

Following gene: 157961231

Centisome position: 32.91

GC content: 35.84

Gene sequence:

>1116_bases
ATGATTGATTTTTTAAACCTTAAAGACATTAATGCTCGATATGCAAAAGATTTAAAAGAAGCTTGCTCTAGGGTTATTGA
CTCTGGCTGGTACGTGTTAGGTAATGAAGTAAGTGAATTTGAAAAAGAGTTCTCTAATTATTGTCAGACAAAGTATTGTT
TGGGAGTTGCCAATGGACTGGATGCCTTAATATTAATTATTCGAGCTTACATTGAGTTAGGCGTTTTCAAAAAAGGCGAC
GAAATTATTGTGCCTTCAAATACCTATATAGCATCCATTTTAGCCATTTCAGAAAATGGCTTGACTCCTGTTTTAGTCGA
GCCAGACATAGATACTTTTAATTTAGACCCCAAAGGTATTGAGGTTGCTATAACCCCTAAAACCAAAGCCATTTTAACGG
TACATTTGTATGGACAAGTTACTGGGATGGACGAAATCAATTCAATTGCTAAAAAGTATGACTTGAAGGTTATTGAAGAT
TGTGCACAGGCTCACGGCGCTTTGTATACTAATAAAAAAAGCGAAGTCAAGAAAGTCGGTTGCTTAGGTGACGCCGCAGG
ATTCAGCTTTTATCCAGGTAAAAATTTAGGAGCATTGGGAGATGCCGGAGCAATAACTACGAGTGATACTGAACTTGCAA
ATACTATCGCTGCTCTGCGAAACTACGGTTCTCATGAAAAGTACATGAACCTTTATAAAGGGGTTAACAGTAGATTGGAT
GAAATTCAAGCCGCTATGTTACGCGTTAAGTTGCGTTATTTGGACAGAGAAATCGTTGCTAGAAAGGCTGTTGCTGATGC
GTACTTAAAGGGAATATATAATCCGCTTATTAAATTGCCTATGGTAGAACAGCCTGATTCTCACGTTTGGCATTTGTTCG
TTATTACAACTAACGAACGCGAAAAATTATCTAAATACCTGACTGATAATAAAATACAGTCGTTAATTCATTATCCGATA
CCTCCACATAAGCAAGAAGCATATAAAGAGCTTAATAATTATAACTTTCCAATTTCAGAAAAGATTCATGAGCAGGTAAT
TAGTATTCCTATTAGTTCAGCAATAACAAATGAACAAATTAATAGGGTTATAGAAACTCTTAATAATTTCAAGTGA

Upstream 100 bases:

>100_bases
GCCCTAGTAGTGAAGAAGGAGTTATCAATGCAGGACTTAATGAATATAAACAAATGATAGGCTGTATCAATACTTTGAAA
GAAACATGGGTATACAATAA

Downstream 100 bases:

>100_bases
TTAGAGGCGAGTATGCAATTGTTTTTATTGGGTGCTGGGCGTCCTGCAAATGGCAATAAACCATCAGCTTTAAAGTCCAT
AGCAAGAAATACTAAAGCTA

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MIDFLNLKDINARYAKDLKEACSRVIDSGWYVLGNEVSEFEKEFSNYCQTKYCLGVANGLDALILIIRAYIELGVFKKGD
EIIVPSNTYIASILAISENGLTPVLVEPDIDTFNLDPKGIEVAITPKTKAILTVHLYGQVTGMDEINSIAKKYDLKVIED
CAQAHGALYTNKKSEVKKVGCLGDAAGFSFYPGKNLGALGDAGAITTSDTELANTIAALRNYGSHEKYMNLYKGVNSRLD
EIQAAMLRVKLRYLDREIVARKAVADAYLKGIYNPLIKLPMVEQPDSHVWHLFVITTNEREKLSKYLTDNKIQSLIHYPI
PPHKQEAYKELNNYNFPISEKIHEQVISIPISSAITNEQINRVIETLNNFK

Sequences:

>Translated_371_residues
MIDFLNLKDINARYAKDLKEACSRVIDSGWYVLGNEVSEFEKEFSNYCQTKYCLGVANGLDALILIIRAYIELGVFKKGD
EIIVPSNTYIASILAISENGLTPVLVEPDIDTFNLDPKGIEVAITPKTKAILTVHLYGQVTGMDEINSIAKKYDLKVIED
CAQAHGALYTNKKSEVKKVGCLGDAAGFSFYPGKNLGALGDAGAITTSDTELANTIAALRNYGSHEKYMNLYKGVNSRLD
EIQAAMLRVKLRYLDREIVARKAVADAYLKGIYNPLIKLPMVEQPDSHVWHLFVITTNEREKLSKYLTDNKIQSLIHYPI
PPHKQEAYKELNNYNFPISEKIHEQVISIPISSAITNEQINRVIETLNNFK
>Mature_371_residues
MIDFLNLKDINARYAKDLKEACSRVIDSGWYVLGNEVSEFEKEFSNYCQTKYCLGVANGLDALILIIRAYIELGVFKKGD
EIIVPSNTYIASILAISENGLTPVLVEPDIDTFNLDPKGIEVAITPKTKAILTVHLYGQVTGMDEINSIAKKYDLKVIED
CAQAHGALYTNKKSEVKKVGCLGDAAGFSFYPGKNLGALGDAGAITTSDTELANTIAALRNYGSHEKYMNLYKGVNSRLD
EIQAAMLRVKLRYLDREIVARKAVADAYLKGIYNPLIKLPMVEQPDSHVWHLFVITTNEREKLSKYLTDNKIQSLIHYPI
PPHKQEAYKELNNYNFPISEKIHEQVISIPISSAITNEQINRVIETLNNFK

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=392, Percent_Identity=28.8265306122449, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI2367285, Length=313, Percent_Identity=29.7124600638978, Blast_Score=117, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 41543; Mature: 41543

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFLNLKDINARYAKDLKEACSRVIDSGWYVLGNEVSEFEKEFSNYCQTKYCLGVANGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCHH
DALILIIRAYIELGVFKKGDEIIVPSNTYIASILAISENGLTPVLVEPDIDTFNLDPKGI
HHHHHHHHHHHHHCCCCCCCEEEECCCHHEEEEEEECCCCCEEEEECCCCCEECCCCCCE
EVAITPKTKAILTVHLYGQVTGMDEINSIAKKYDLKVIEDCAQAHGALYTNKKSEVKKVG
EEEECCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHC
CLGDAAGFSFYPGKNLGALGDAGAITTSDTELANTIAALRNYGSHEKYMNLYKGVNSRLD
CCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EIQAAMLRVKLRYLDREIVARKAVADAYLKGIYNPLIKLPMVEQPDSHVWHLFVITTNER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCH
EKLSKYLTDNKIQSLIHYPIPPHKQEAYKELNNYNFPISEKIHEQVISIPISSAITNEQI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHH
NRVIETLNNFK
HHHHHHHHCCC
>Mature Secondary Structure
MIDFLNLKDINARYAKDLKEACSRVIDSGWYVLGNEVSEFEKEFSNYCQTKYCLGVANGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCHH
DALILIIRAYIELGVFKKGDEIIVPSNTYIASILAISENGLTPVLVEPDIDTFNLDPKGI
HHHHHHHHHHHHHCCCCCCCEEEECCCHHEEEEEEECCCCCEEEEECCCCCEECCCCCCE
EVAITPKTKAILTVHLYGQVTGMDEINSIAKKYDLKVIEDCAQAHGALYTNKKSEVKKVG
EEEECCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHC
CLGDAAGFSFYPGKNLGALGDAGAITTSDTELANTIAALRNYGSHEKYMNLYKGVNSRLD
CCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EIQAAMLRVKLRYLDREIVARKAVADAYLKGIYNPLIKLPMVEQPDSHVWHLFVITTNER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCH
EKLSKYLTDNKIQSLIHYPIPPHKQEAYKELNNYNFPISEKIHEQVISIPISSAITNEQI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHH
NRVIETLNNFK
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]