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The map label for this gene is cheA [H]

Identifier: 157961209

GI number: 157961209

Start: 1677668

End: 1679893

Strand: Direct

Name: cheA [H]

Synonym: Spea_1381

Alternate gene names: 157961209

Gene position: 1677668-1679893 (Clockwise)

Preceding gene: 157961208

Following gene: 157961210

Centisome position: 32.42

GC content: 46.36

Gene sequence:

>2226_bases
ATGTCCTTTGATGTTGATGAAGAGATACTGCAGGACTTTTTGATCGAAGCTGGTGAGATTTTAGAGCTTCTACAAGAACA
ACTAGTCACGTTAGAAAATAATCCGGATGATACCGAACTGCTAAATGCGATATTTAGAGGTTTCCATACGGTTAAAGGCG
GCGCGGGCTTCTTAGGTTTATCTCCAATGGTAGATGTTTGCCATGAAGCAGAAAATACCTTCGATCTTTTGCGTACTGGG
AAGCGTGAAGTTTCTGCTAATTTGATGGATGTCATTTTACAAGCGGTCGACTCAATCAACTCAATGTTTGCTGAAACTCA
AGCAGGGCAGACTCAATCTCCAGCTGAGCCAACATTGTTAGCTCAGCTGAAAACCTTAAGCGCAGGTGAGCTACTGCCAT
CTGAGATGGAACAAACAGTCGCCTCTCCTGCCGCTGTAGAGCCCACCGTCAGCGTTCAAGAACCGACTATTGAAGCCGTG
GCGCCGCAAGAGACGCAGGTGATAGAACAGGCTACAGCAACTACTGGTAGCATAGATGATATTGATGATATCGAATTTGA
AGCCTTACTCGATGCTCTGCATGGTTCGGGTAACGGTCCTGGTAAGCCTGTTGAGTCGACTTCTATCTCCTCTTTACCTG
CATCAGATGATATTAGCGATGATGAATTTGAATCTTTACTCGATGAGTTACATGGCTCTGGTCAGTTTAAAGTTCAGTCG
GCAGCGCCTGCGGTTATCGAACCAAGTGGTTCTCAAGTCGATTCTGATGAAATAACCGATGATGAGTTTGAACGTTTGCT
GGATGAATTGCACGGTTCAGGCACTGGCCCAGGAAAGTCAGCTAATGTGAACGATACCAGTGAAGCGGTTTCTGAACTGC
CTGAAGTCAATCAATCTCAGCCTGTAGTGCAAGCGATAACAACATCGCAGCAGGTGCCTGCTGTTAACGCTGAAGTTAAA
ACCGAGATAAAGCCACATCCTAAACCAGACGTTAAACCTGCAGCAGCTAAAGTTGCGCCAAAGGCGGCTGGCAATAATGC
GCCTCAAGCTGAAACCACAGTGCGGGTTGATACTTCAAGACTCGATCAAATCATGAATATGGTTGGTGAATTGGTATTAG
TGCGCAATCGTCTACTCAGCCTAGGCGTAGCACGTGAAGATGAGGATATGTCAAAGGCTTTAGCCAACCTTGACTTAGTC
ACAGCTGACCTTCAAGGCGCAGTGATGAAAACTCGCATGCAGCCAATTAAGAAAGTTTTCGGCCGCTTCCCTCGCGTTGT
TCGTGATTTAGCCCGTAGCTTAAACAAAGAAATTGACCTTGTTATGATCGGTGAAGATACCGATTTAGATAAGAATCTCG
TCGAAGCGTTAGCCGATCCCTTAGTTCACTTAGTGAGGAACTCGGTCGATCATGGTATTGAAATGCCAGATGCTCGTGAA
GAGAACGGTAAAACACGCACGGGCACAATTACTTTATCAGCGAGTCAAGAAGGCGACCATATCCTGCTTAAGATTGAGGA
TGATGGGGCAGGTATGGATCCTGACAAGCTTAAAGGGATCGCAATCAGTCGAGGCGTTCTCGATGAAGATTCCGCCGCGC
GTATGAGCGACGAAGAAGCCTATAACCTTATTTTTGCCCCAGGCTTCTCGACTAAAGTTGAGGTTTCTGATATCTCGGGT
CGTGGCGTAGGCATGGATGTGGTGAAAACCCGCATTACCCAGTTAAATGGTTCGGTTCATATCGACTCACAACTAGGTAA
GGGCACGCGTCTAGAGATTAAGGTGCCGTTGACCCTTGCGATAATGCCGACCTTAATGGTTGAAGTTGCCGAGCAGGTGT
TTGCTTTACCGCTGTCGAGTGTCAATGAAATTTTCCATTTAGACTTGACTAAGACTAACGTGGTTGATGGCCAATTGACG
GTTATTGTTCGTAATAAAGCGGTGCCATTATTTTATTTAGAGCAGTGGCTATCTCGTAAGCAATTGAGCTTTAAGCATGG
TGATAAACAGCATGGGCACGTCGTCATCGTTCAGTTAGGCACGATGCAGATTGGCTTTGTGGTGGATTCACTTATAGGCC
AAGAAGAGGTGGTGATTAAGCCACTAGGAACATTGCTTCATGGTACACCGGGCATGGCGGGAGCCACCATTACTTCAGAT
GGCGGCATCGCACTGATTTTAGATGTACCAGGACTACTTAAGCATTACGCACGTAACAGGAGCTAA

Upstream 100 bases:

>100_bases
AGGTCCTATTATGAACGCAGAGCACCGCCAGGACGTGGTGACGGGTCAAGATGAAGTTGACGATCTGCTTTCGAGCTTAG
GTTTTTAAGGGAGTCAAAGA

Downstream 100 bases:

>100_bases
CACTGGTTAGCATAGGGAATAACGCAGCTTGTTATTCCCTTTTTTACATACAGCATTGAGCAGGCCTGTGGTGCAGTAAA
GGAATTTGAATGGGCATTAA

Product: signal transduction histidine kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MSFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGLSPMVDVCHEAENTFDLLRTG
KREVSANLMDVILQAVDSINSMFAETQAGQTQSPAEPTLLAQLKTLSAGELLPSEMEQTVASPAAVEPTVSVQEPTIEAV
APQETQVIEQATATTGSIDDIDDIEFEALLDALHGSGNGPGKPVESTSISSLPASDDISDDEFESLLDELHGSGQFKVQS
AAPAVIEPSGSQVDSDEITDDEFERLLDELHGSGTGPGKSANVNDTSEAVSELPEVNQSQPVVQAITTSQQVPAVNAEVK
TEIKPHPKPDVKPAAAKVAPKAAGNNAPQAETTVRVDTSRLDQIMNMVGELVLVRNRLLSLGVAREDEDMSKALANLDLV
TADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKEIDLVMIGEDTDLDKNLVEALADPLVHLVRNSVDHGIEMPDARE
ENGKTRTGTITLSASQEGDHILLKIEDDGAGMDPDKLKGIAISRGVLDEDSAARMSDEEAYNLIFAPGFSTKVEVSDISG
RGVGMDVVKTRITQLNGSVHIDSQLGKGTRLEIKVPLTLAIMPTLMVEVAEQVFALPLSSVNEIFHLDLTKTNVVDGQLT
VIVRNKAVPLFYLEQWLSRKQLSFKHGDKQHGHVVIVQLGTMQIGFVVDSLIGQEEVVIKPLGTLLHGTPGMAGATITSD
GGIALILDVPGLLKHYARNRS

Sequences:

>Translated_741_residues
MSFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGLSPMVDVCHEAENTFDLLRTG
KREVSANLMDVILQAVDSINSMFAETQAGQTQSPAEPTLLAQLKTLSAGELLPSEMEQTVASPAAVEPTVSVQEPTIEAV
APQETQVIEQATATTGSIDDIDDIEFEALLDALHGSGNGPGKPVESTSISSLPASDDISDDEFESLLDELHGSGQFKVQS
AAPAVIEPSGSQVDSDEITDDEFERLLDELHGSGTGPGKSANVNDTSEAVSELPEVNQSQPVVQAITTSQQVPAVNAEVK
TEIKPHPKPDVKPAAAKVAPKAAGNNAPQAETTVRVDTSRLDQIMNMVGELVLVRNRLLSLGVAREDEDMSKALANLDLV
TADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKEIDLVMIGEDTDLDKNLVEALADPLVHLVRNSVDHGIEMPDARE
ENGKTRTGTITLSASQEGDHILLKIEDDGAGMDPDKLKGIAISRGVLDEDSAARMSDEEAYNLIFAPGFSTKVEVSDISG
RGVGMDVVKTRITQLNGSVHIDSQLGKGTRLEIKVPLTLAIMPTLMVEVAEQVFALPLSSVNEIFHLDLTKTNVVDGQLT
VIVRNKAVPLFYLEQWLSRKQLSFKHGDKQHGHVVIVQLGTMQIGFVVDSLIGQEEVVIKPLGTLLHGTPGMAGATITSD
GGIALILDVPGLLKHYARNRS
>Mature_740_residues
SFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGLSPMVDVCHEAENTFDLLRTGK
REVSANLMDVILQAVDSINSMFAETQAGQTQSPAEPTLLAQLKTLSAGELLPSEMEQTVASPAAVEPTVSVQEPTIEAVA
PQETQVIEQATATTGSIDDIDDIEFEALLDALHGSGNGPGKPVESTSISSLPASDDISDDEFESLLDELHGSGQFKVQSA
APAVIEPSGSQVDSDEITDDEFERLLDELHGSGTGPGKSANVNDTSEAVSELPEVNQSQPVVQAITTSQQVPAVNAEVKT
EIKPHPKPDVKPAAAKVAPKAAGNNAPQAETTVRVDTSRLDQIMNMVGELVLVRNRLLSLGVAREDEDMSKALANLDLVT
ADLQGAVMKTRMQPIKKVFGRFPRVVRDLARSLNKEIDLVMIGEDTDLDKNLVEALADPLVHLVRNSVDHGIEMPDAREE
NGKTRTGTITLSASQEGDHILLKIEDDGAGMDPDKLKGIAISRGVLDEDSAARMSDEEAYNLIFAPGFSTKVEVSDISGR
GVGMDVVKTRITQLNGSVHIDSQLGKGTRLEIKVPLTLAIMPTLMVEVAEQVFALPLSSVNEIFHLDLTKTNVVDGQLTV
IVRNKAVPLFYLEQWLSRKQLSFKHGDKQHGHVVIVQLGTMQIGFVVDSLIGQEEVVIKPLGTLLHGTPGMAGATITSDG
GIALILDVPGLLKHYARNRS

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=426, Percent_Identity=40.1408450704225, Blast_Score=289, Evalue=5e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79598; Mature: 79467

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS50851 CHEW ; PS00018 EF_HAND_1 ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGL
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
SPMVDVCHEAENTFDLLRTGKREVSANLMDVILQAVDSINSMFAETQAGQTQSPAEPTLL
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
AQLKTLSAGELLPSEMEQTVASPAAVEPTVSVQEPTIEAVAPQETQVIEQATATTGSIDD
HHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCCCCC
IDDIEFEALLDALHGSGNGPGKPVESTSISSLPASDDISDDEFESLLDELHGSGQFKVQS
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEC
AAPAVIEPSGSQVDSDEITDDEFERLLDELHGSGTGPGKSANVNDTSEAVSELPEVNQSQ
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCC
PVVQAITTSQQVPAVNAEVKTEIKPHPKPDVKPAAAKVAPKAAGNNAPQAETTVRVDTSR
CHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECHHH
LDQIMNMVGELVLVRNRLLSLGVAREDEDMSKALANLDLVTADLQGAVMKTRMQPIKKVF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHH
GRFPRVVRDLARSLNKEIDLVMIGEDTDLDKNLVEALADPLVHLVRNSVDHGIEMPDARE
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ENGKTRTGTITLSASQEGDHILLKIEDDGAGMDPDKLKGIAISRGVLDEDSAARMSDEEA
CCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHCCEEEECCCCCCCCHHHCCCCCC
YNLIFAPGFSTKVEVSDISGRGVGMDVVKTRITQLNGSVHIDSQLGKGTRLEIKVPLTLA
EEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCHHH
IMPTLMVEVAEQVFALPLSSVNEIFHLDLTKTNVVDGQLTVIVRNKAVPLFYLEQWLSRK
HHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCEEECCEEEEEEECCCCCHHHHHHHHHHH
QLSFKHGDKQHGHVVIVQLGTMQIGFVVDSLIGQEEVVIKPLGTLLHGTPGMAGATITSD
HCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCEEECC
GGIALILDVPGLLKHYARNRS
CCEEEEEECCHHHHHHHCCCC
>Mature Secondary Structure 
SFDVDEEILQDFLIEAGEILELLQEQLVTLENNPDDTELLNAIFRGFHTVKGGAGFLGL
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
SPMVDVCHEAENTFDLLRTGKREVSANLMDVILQAVDSINSMFAETQAGQTQSPAEPTLL
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
AQLKTLSAGELLPSEMEQTVASPAAVEPTVSVQEPTIEAVAPQETQVIEQATATTGSIDD
HHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCCCCC
IDDIEFEALLDALHGSGNGPGKPVESTSISSLPASDDISDDEFESLLDELHGSGQFKVQS
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEC
AAPAVIEPSGSQVDSDEITDDEFERLLDELHGSGTGPGKSANVNDTSEAVSELPEVNQSQ
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCC
PVVQAITTSQQVPAVNAEVKTEIKPHPKPDVKPAAAKVAPKAAGNNAPQAETTVRVDTSR
CHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECHHH
LDQIMNMVGELVLVRNRLLSLGVAREDEDMSKALANLDLVTADLQGAVMKTRMQPIKKVF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHH
GRFPRVVRDLARSLNKEIDLVMIGEDTDLDKNLVEALADPLVHLVRNSVDHGIEMPDARE
HHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ENGKTRTGTITLSASQEGDHILLKIEDDGAGMDPDKLKGIAISRGVLDEDSAARMSDEEA
CCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHCCEEEECCCCCCCCHHHCCCCCC
YNLIFAPGFSTKVEVSDISGRGVGMDVVKTRITQLNGSVHIDSQLGKGTRLEIKVPLTLA
EEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCHHH
IMPTLMVEVAEQVFALPLSSVNEIFHLDLTKTNVVDGQLTVIVRNKAVPLFYLEQWLSRK
HHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCEEECCEEEEEEECCCCCHHHHHHHHHHH
QLSFKHGDKQHGHVVIVQLGTMQIGFVVDSLIGQEEVVIKPLGTLLHGTPGMAGATITSD
HCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCEEECC
GGIALILDVPGLLKHYARNRS
CCEEEEEECCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]