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The map label for this gene is cya2 [H]

Identifier: 157960847

GI number: 157960847

Start: 1241646

End: 1242719

Strand: Reverse

Name: cya2 [H]

Synonym: Spea_1019

Alternate gene names: 157960847

Gene position: 1242719-1241646 (Counterclockwise)

Preceding gene: 157960848

Following gene: 157960846

Centisome position: 24.02

GC content: 44.32

Gene sequence:

>1074_bases
GTGAAAGCACATATACAAGCGAAGAAATTAGCCTTTGCTATGTTCGCTTGGACTGCAGCCATGGCGGCTTTCGTATTCTT
TAGATACGCGCAAACTCCTGAACTTCCACAGTGGGCCATCGGTTCCGCTGACTTAGCCACGCTTTCTATTTATATGGGTA
TTATTTTCGGCAGCCTTCACTGGATGTCGAACTTGATCGCTGATTTTAGTGCTATCAACCGCTTACCTTACGTTTTCTCT
GTCGTGTTCAAAGGGCTTTTCTTACTGCTTGGCGCGACGACTCTGGCTTATATTACCCAGTACCTCAACATGTGGGCCAT
TGAGAATCACATGACAACCTTGCGCCAAATGTTAACAGCGCACATTCTCTATAGTCCTTCATTCCAAGCACTGATCGTCT
ACTTGGTTGTGGTTCGTGTTGGCCTCGCTTTTATTGAACAGATGGCGCTACTTGTTGGCCCAAGAGTGTTATTGAATATC
GGCTTAGGTAAATATCATAAACCTAGATATGAACAGCGCTTATTTCTTTATTTAGATATGGTGGCCTCAACTACTCATGC
CGAGTCTCTTGGCGATTATCGTTTCAGCCGCTTAATCCAAGATAGCTTTAGTCTGTTAGCCGATACTGTCACTAACAATG
AAGCTGAAATATATCGCTATATGGGCGATGCAGTATTGATCCACTGGCCACTAAAAGACGGCATTAAAGAAGACCGATGC
TTCAATATTTATCATGAGTTCAGTCAGCAACTCAGCTGGCAGAGACAATATTTTGAAGAGCAGTACGGCTTCGTACCAAA
ATTTAAGGCTGCGGCTCACTGTGGACAAGTCGTGGCTGCGGTTGTGGGCGTACAGAAGCAAGAGATTAGCTTCTTTAGCG
ACGTACTTAATACGTTAGCGCGACTACAAGATCAGTGTAACCCTCTGGGGCAACGCATGCTTATTTCAGGCTCATTACAA
TCACGACTCGAATATAGCGACTCACAATATAATCTAAACAGTCTAGGCCCCATTAAGCTAAAGGGTAAGCAGCACTCCAT
CGAAGTCTTTGGTGTTTCGCCTAAAAATACCTAA

Upstream 100 bases:

>100_bases
TCATTTGACTTAGATCACAAATACTACTGGTAAAAGTAGGGGGATATTCTATAAAATGGCGCCTCCTAAAATTATGTAGT
ATTTGGATACCCCCTTAATA

Downstream 100 bases:

>100_bases
AACATATAAACAAAAAGCCGATAATCATATCGGCTTTTTTGTTTTATTTTATGTCCCGTCCTGAGATAAGTTGACACATT
GGAGACTTATCTATGAAACC

Product: putative adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2 [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKAHIQAKKLAFAMFAWTAAMAAFVFFRYAQTPELPQWAIGSADLATLSIYMGIIFGSLHWMSNLIADFSAINRLPYVFS
VVFKGLFLLLGATTLAYITQYLNMWAIENHMTTLRQMLTAHILYSPSFQALIVYLVVVRVGLAFIEQMALLVGPRVLLNI
GLGKYHKPRYEQRLFLYLDMVASTTHAESLGDYRFSRLIQDSFSLLADTVTNNEAEIYRYMGDAVLIHWPLKDGIKEDRC
FNIYHEFSQQLSWQRQYFEEQYGFVPKFKAAAHCGQVVAAVVGVQKQEISFFSDVLNTLARLQDQCNPLGQRMLISGSLQ
SRLEYSDSQYNLNSLGPIKLKGKQHSIEVFGVSPKNT

Sequences:

>Translated_357_residues
MKAHIQAKKLAFAMFAWTAAMAAFVFFRYAQTPELPQWAIGSADLATLSIYMGIIFGSLHWMSNLIADFSAINRLPYVFS
VVFKGLFLLLGATTLAYITQYLNMWAIENHMTTLRQMLTAHILYSPSFQALIVYLVVVRVGLAFIEQMALLVGPRVLLNI
GLGKYHKPRYEQRLFLYLDMVASTTHAESLGDYRFSRLIQDSFSLLADTVTNNEAEIYRYMGDAVLIHWPLKDGIKEDRC
FNIYHEFSQQLSWQRQYFEEQYGFVPKFKAAAHCGQVVAAVVGVQKQEISFFSDVLNTLARLQDQCNPLGQRMLISGSLQ
SRLEYSDSQYNLNSLGPIKLKGKQHSIEVFGVSPKNT
>Mature_357_residues
MKAHIQAKKLAFAMFAWTAAMAAFVFFRYAQTPELPQWAIGSADLATLSIYMGIIFGSLHWMSNLIADFSAINRLPYVFS
VVFKGLFLLLGATTLAYITQYLNMWAIENHMTTLRQMLTAHILYSPSFQALIVYLVVVRVGLAFIEQMALLVGPRVLLNI
GLGKYHKPRYEQRLFLYLDMVASTTHAESLGDYRFSRLIQDSFSLLADTVTNNEAEIYRYMGDAVLIHWPLKDGIKEDRC
FNIYHEFSQQLSWQRQYFEEQYGFVPKFKAAAHCGQVVAAVVGVQKQEISFFSDVLNTLARLQDQCNPLGQRMLISGSLQ
SRLEYSDSQYNLNSLGPIKLKGKQHSIEVFGVSPKNT

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 40595; Mature: 40595

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAHIQAKKLAFAMFAWTAAMAAFVFFRYAQTPELPQWAIGSADLATLSIYMGIIFGSLH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
WMSNLIADFSAINRLPYVFSVVFKGLFLLLGATTLAYITQYLNMWAIENHMTTLRQMLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HILYSPSFQALIVYLVVVRVGLAFIEQMALLVGPRVLLNIGLGKYHKPRYEQRLFLYLDM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCHHHHHHHHHHHH
VASTTHAESLGDYRFSRLIQDSFSLLADTVTNNEAEIYRYMGDAVLIHWPLKDGIKEDRC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCCCHHHH
FNIYHEFSQQLSWQRQYFEEQYGFVPKFKAAAHCGQVVAAVVGVQKQEISFFSDVLNTLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RLQDQCNPLGQRMLISGSLQSRLEYSDSQYNLNSLGPIKLKGKQHSIEVFGVSPKNT
HHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure
MKAHIQAKKLAFAMFAWTAAMAAFVFFRYAQTPELPQWAIGSADLATLSIYMGIIFGSLH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
WMSNLIADFSAINRLPYVFSVVFKGLFLLLGATTLAYITQYLNMWAIENHMTTLRQMLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HILYSPSFQALIVYLVVVRVGLAFIEQMALLVGPRVLLNIGLGKYHKPRYEQRLFLYLDM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCHHHHHHHHHHHH
VASTTHAESLGDYRFSRLIQDSFSLLADTVTNNEAEIYRYMGDAVLIHWPLKDGIKEDRC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCCCHHHH
FNIYHEFSQQLSWQRQYFEEQYGFVPKFKAAAHCGQVVAAVVGVQKQEISFFSDVLNTLA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RLQDQCNPLGQRMLISGSLQSRLEYSDSQYNLNSLGPIKLKGKQHSIEVFGVSPKNT
HHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7750735; 11481430 [H]