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The map label for this gene is yiaV [H]

Identifier: 157960701

GI number: 157960701

Start: 1072069

End: 1073205

Strand: Direct

Name: yiaV [H]

Synonym: Spea_0873

Alternate gene names: 157960701

Gene position: 1072069-1073205 (Clockwise)

Preceding gene: 157960700

Following gene: 157960702

Centisome position: 20.72

GC content: 47.93

Gene sequence:

>1137_bases
ATGGATTTACTACTCGTATTGACCTATACCGCTATCTGCATTGCGATTTTCAAGATATTTAAGATCCCACTGACCAAGTG
GACGGTACCGACCGCCATACTCGGCGGCATATTTATCGTCGGTGCCTTGATCTTACTGATGAACTATAACCACCCTTATA
CGCCATTTGCGAAAGAGTATTTCGTTACCACCCCAATTAATCCCGCGGTTCGGGGCGTAGTTGTATCGGTAGAGGTTGAG
CCTAATACTCCGATTAAGAAGGGAGACGTGTTATTTAGGATCGACCCAACCCCCTTTCAAGCGATTGTGAAGCAAAAGCG
TGCAGCGTTAGTTGCGGCCGAGCTTGAAGTACCACAGCTAGAGGCCGCGTGGGAAACCGCAAGAGCATCGGTCACAAGGG
CGACCGCTGATAGAGATAGAACTAAATCGGCATTCGATCGTTATGAAAAAGGACGTAAGCGCGGTGGGGTTAACTCACCC
TTTACAGAGCTTGAGCTCGATAACAAACGTCAGCTTTATTTTGCATCTGAAGCACAATTAACCGCTGCTAACGCAGAGGA
GTTAAGGGTTCGTTTAGCTTATGAGTCAAACGTCGATGGCGTTAATACCAAGGTCGCAGGCATTCAAGGTGAGCTTGAAA
AAGCGCAGTTCGAACTTGAGCAGACTGTGGTCAAGGCTCCTGCCGATGGCATGGTGACCCAGATGGCACTCCGCCCGGGT
ATTGTGGCTGTGCCTATGCCATTAAGACCCTTACTAAGCTTTATTCCTGATGAAGAGCGGGCTTTTGTGGGGGCATTTTG
GCAGAACTCATTACTCAGATTAAAAGAAGGGGATGAAGCTGAGGTAATTTTAGATGGTGCGCCGGGGCAAGTATTTAAAG
GTAGAGTGGCTAAAGTCTTACCAGCCATGGCCGAAGGTGAGATCCAGTCATCAGGTTCTTTGATTTCATCGAATCGTTTA
ATGACACGAGGCAGAGCCTTAGTACTGATTAAACTTGAAGATCATGAAGTTCGAACGCGCTTCCCAGCGGGTGTTTCGGG
TCATGCGGCTATCTACACCGAGCACTTTGCTCATGTATCAGTGATGCGACGAGTCTTATTAAGAATGCAGGGCTGGCTAA
ACTACCTATTCCACTAA

Upstream 100 bases:

>100_bases
ATGGAGGCGTCTCAGTGTGGAGCCAAGCCCGTAACCTCGTCAGCCAAGACACAAGCTCCTAATATGACTGATTCTCAATC
TGACGGCGCAGAGGTGTAAC

Downstream 100 bases:

>100_bases
TAGATGCAATAAAACTGTGGTTGATACTGCTACAATGTTGAACTGCACTTGATATAAAGGGACCTTAGCGTCCCTTTTCT
TTTGGGTAATATGCTAAAGC

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MDLLLVLTYTAICIAIFKIFKIPLTKWTVPTAILGGIFIVGALILLMNYNHPYTPFAKEYFVTTPINPAVRGVVVSVEVE
PNTPIKKGDVLFRIDPTPFQAIVKQKRAALVAAELEVPQLEAAWETARASVTRATADRDRTKSAFDRYEKGRKRGGVNSP
FTELELDNKRQLYFASEAQLTAANAEELRVRLAYESNVDGVNTKVAGIQGELEKAQFELEQTVVKAPADGMVTQMALRPG
IVAVPMPLRPLLSFIPDEERAFVGAFWQNSLLRLKEGDEAEVILDGAPGQVFKGRVAKVLPAMAEGEIQSSGSLISSNRL
MTRGRALVLIKLEDHEVRTRFPAGVSGHAAIYTEHFAHVSVMRRVLLRMQGWLNYLFH

Sequences:

>Translated_378_residues
MDLLLVLTYTAICIAIFKIFKIPLTKWTVPTAILGGIFIVGALILLMNYNHPYTPFAKEYFVTTPINPAVRGVVVSVEVE
PNTPIKKGDVLFRIDPTPFQAIVKQKRAALVAAELEVPQLEAAWETARASVTRATADRDRTKSAFDRYEKGRKRGGVNSP
FTELELDNKRQLYFASEAQLTAANAEELRVRLAYESNVDGVNTKVAGIQGELEKAQFELEQTVVKAPADGMVTQMALRPG
IVAVPMPLRPLLSFIPDEERAFVGAFWQNSLLRLKEGDEAEVILDGAPGQVFKGRVAKVLPAMAEGEIQSSGSLISSNRL
MTRGRALVLIKLEDHEVRTRFPAGVSGHAAIYTEHFAHVSVMRRVLLRMQGWLNYLFH
>Mature_378_residues
MDLLLVLTYTAICIAIFKIFKIPLTKWTVPTAILGGIFIVGALILLMNYNHPYTPFAKEYFVTTPINPAVRGVVVSVEVE
PNTPIKKGDVLFRIDPTPFQAIVKQKRAALVAAELEVPQLEAAWETARASVTRATADRDRTKSAFDRYEKGRKRGGVNSP
FTELELDNKRQLYFASEAQLTAANAEELRVRLAYESNVDGVNTKVAGIQGELEKAQFELEQTVVKAPADGMVTQMALRPG
IVAVPMPLRPLLSFIPDEERAFVGAFWQNSLLRLKEGDEAEVILDGAPGQVFKGRVAKVLPAMAEGEIQSSGSLISSNRL
MTRGRALVLIKLEDHEVRTRFPAGVSGHAAIYTEHFAHVSVMRRVLLRMQGWLNYLFH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=377, Percent_Identity=46.4190981432361, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI1790024, Length=377, Percent_Identity=43.5013262599469, Blast_Score=338, Evalue=4e-94,
Organism=Escherichia coli, GI1790519, Length=257, Percent_Identity=27.6264591439689, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41913; Mature: 41913

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLVLTYTAICIAIFKIFKIPLTKWTVPTAILGGIFIVGALILLMNYNHPYTPFAKEY
CCEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
FVTTPINPAVRGVVVSVEVEPNTPIKKGDVLFRIDPTPFQAIVKQKRAALVAAELEVPQL
EEECCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHEEEEECCCCCH
EAAWETARASVTRATADRDRTKSAFDRYEKGRKRGGVNSPFTELELDNKRQLYFASEAQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCEE
TAANAEELRVRLAYESNVDGVNTKVAGIQGELEKAQFELEQTVVKAPADGMVTQMALRPG
EECCHHHEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
IVAVPMPLRPLLSFIPDEERAFVGAFWQNSLLRLKEGDEAEVILDGAPGQVFKGRVAKVL
EEEECCCHHHHHHHCCCCHHHEEEHHHHCCEEEECCCCCCEEEEECCCCHHHHHHHHHHH
PAMAEGEIQSSGSLISSNRLMTRGRALVLIKLEDHEVRTRFPAGVSGHAAIYTEHFAHVS
HHHHCCCCCCCCCEEECCCEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHH
VMRRVLLRMQGWLNYLFH
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLLLVLTYTAICIAIFKIFKIPLTKWTVPTAILGGIFIVGALILLMNYNHPYTPFAKEY
CCEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
FVTTPINPAVRGVVVSVEVEPNTPIKKGDVLFRIDPTPFQAIVKQKRAALVAAELEVPQL
EEECCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHEEEEECCCCCH
EAAWETARASVTRATADRDRTKSAFDRYEKGRKRGGVNSPFTELELDNKRQLYFASEAQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCEE
TAANAEELRVRLAYESNVDGVNTKVAGIQGELEKAQFELEQTVVKAPADGMVTQMALRPG
EECCHHHEEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
IVAVPMPLRPLLSFIPDEERAFVGAFWQNSLLRLKEGDEAEVILDGAPGQVFKGRVAKVL
EEEECCCHHHHHHHCCCCHHHEEEHHHHCCEEEECCCCCCEEEEECCCCHHHHHHHHHHH
PAMAEGEIQSSGSLISSNRLMTRGRALVLIKLEDHEVRTRFPAGVSGHAAIYTEHFAHVS
HHHHCCCCCCCCCEEECCCEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHH
VMRRVLLRMQGWLNYLFH
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]