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The map label for this gene is xerD [H]

Identifier: 157960633

GI number: 157960633

Start: 998105

End: 999007

Strand: Direct

Name: xerD [H]

Synonym: Spea_0805

Alternate gene names: 157960633

Gene position: 998105-999007 (Clockwise)

Preceding gene: 157960632

Following gene: 157960634

Centisome position: 19.29

GC content: 51.27

Gene sequence:

>903_bases
GTGTCAGAGAAGTACACGCCCAATAGTATTATTGATCTGTTTTTAGATGACTTATGGTCAACCAAGGGCTTAAGCGATAA
CACCTTGAGCGCCTATCGCACCGATCTGCGTCATCTCGACCGTTACTTGCAAAAGCAAGGTGACGATCTAGTGACTTGTT
CTCAGTTCGACATCCGCAACTATTTGGCTGAGCGCTTCGACAAAGGCTTCGCTAAGACCAGTAGCGCGCGCATGATGAGT
AGCCTTAGACGCTTCTATGGCTACCTTATTGTCAAAAAGCAGATCGATAGCGACCCGATGGCACTGATTGAGTCCCCCAA
ACTTGCGCGAAAGTTGCCTGACTCCCTCAGTGAAGAAGATATCGACCGTTTGCTGGCCGAACCTGAACAAGACGATCCGA
TAGAGAGTCGTGATAAAGCCATGCTTGAGCTGCTATACGCCACAGGGCTTCGTGTGTCAGAGCTGGTGGGACTGACCATG
GAGCAGCTAAGTCTGCGCCAAGGTCTGGTGCGCATTACCGGTAAAGGTGGCAAGGAGCGTCTAGTACCGCTGGGGGAGCT
GGCCATCACCGAGATAGAGTCATACCTTAAATTTGCCAGAGCCGAGCTACTCAAGGGCAAGCAGAGTGATGTGCTATTTC
CATCGAAACGGGCGCAGCAGATGACTCGTCAGACGTTTTGGCACCGTATCAAGCTTTATGCGCTTAGAGCGGGGATCAGC
ACAGAGCTTTCTCCGCATACTTTAAGGCATGCATTCGCGACCCATCTACTTAACCATGGTGCAGATCTGCGCGTGGTGCA
ACTGTTGCTGGGTCACAGCGACCTGTCGACAACACAGATCTATACTCATGTGGCCACAGCAAGATTAGCTAGCCTACATA
GCGAGCATCATCCAAGAGGCTGA

Upstream 100 bases:

>100_bases
TATGGCTTTTGCTTTTCCTAGTAGGGCTTTAGCCCGTCCTCGCAGCGAAGCGTCCTAGGATCTAGGTCCTTCTTTATTAA
ATCGTAGGTAGGAATAATAA

Downstream 100 bases:

>100_bases
TTTAAGCAGCTTGATATGCATCTGCTGTTACAATTTGTTGGCTGGTGAATATCTTTCAGCAAATCTAGACTTAAACATAA
ATATTTGATGGATTTCACGT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSEKYTPNSIIDLFLDDLWSTKGLSDNTLSAYRTDLRHLDRYLQKQGDDLVTCSQFDIRNYLAERFDKGFAKTSSARMMS
SLRRFYGYLIVKKQIDSDPMALIESPKLARKLPDSLSEEDIDRLLAEPEQDDPIESRDKAMLELLYATGLRVSELVGLTM
EQLSLRQGLVRITGKGGKERLVPLGELAITEIESYLKFARAELLKGKQSDVLFPSKRAQQMTRQTFWHRIKLYALRAGIS
TELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATARLASLHSEHHPRG

Sequences:

>Translated_300_residues
MSEKYTPNSIIDLFLDDLWSTKGLSDNTLSAYRTDLRHLDRYLQKQGDDLVTCSQFDIRNYLAERFDKGFAKTSSARMMS
SLRRFYGYLIVKKQIDSDPMALIESPKLARKLPDSLSEEDIDRLLAEPEQDDPIESRDKAMLELLYATGLRVSELVGLTM
EQLSLRQGLVRITGKGGKERLVPLGELAITEIESYLKFARAELLKGKQSDVLFPSKRAQQMTRQTFWHRIKLYALRAGIS
TELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATARLASLHSEHHPRG
>Mature_299_residues
SEKYTPNSIIDLFLDDLWSTKGLSDNTLSAYRTDLRHLDRYLQKQGDDLVTCSQFDIRNYLAERFDKGFAKTSSARMMSS
LRRFYGYLIVKKQIDSDPMALIESPKLARKLPDSLSEEDIDRLLAEPEQDDPIESRDKAMLELLYATGLRVSELVGLTME
QLSLRQGLVRITGKGGKERLVPLGELAITEIESYLKFARAELLKGKQSDVLFPSKRAQQMTRQTFWHRIKLYALRAGIST
ELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATARLASLHSEHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=62.8865979381443, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1790244, Length=278, Percent_Identity=38.1294964028777, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1790768, Length=158, Percent_Identity=33.5443037974684, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790767, Length=187, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34124; Mature: 33992

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKYTPNSIIDLFLDDLWSTKGLSDNTLSAYRTDLRHLDRYLQKQGDDLVTCSQFDIRN
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
YLAERFDKGFAKTSSARMMSSLRRFYGYLIVKKQIDSDPMALIESPKLARKLPDSLSEED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHCCCCCCHHH
IDRLLAEPEQDDPIESRDKAMLELLYATGLRVSELVGLTMEQLSLRQGLVRITGKGGKER
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
LVPLGELAITEIESYLKFARAELLKGKQSDVLFPSKRAQQMTRQTFWHRIKLYALRAGIS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATARLASLHSEHHPRG
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEKYTPNSIIDLFLDDLWSTKGLSDNTLSAYRTDLRHLDRYLQKQGDDLVTCSQFDIRN
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
YLAERFDKGFAKTSSARMMSSLRRFYGYLIVKKQIDSDPMALIESPKLARKLPDSLSEED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHCCCCCCHHH
IDRLLAEPEQDDPIESRDKAMLELLYATGLRVSELVGLTMEQLSLRQGLVRITGKGGKER
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
LVPLGELAITEIESYLKFARAELLKGKQSDVLFPSKRAQQMTRQTFWHRIKLYALRAGIS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
TELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVATARLASLHSEHHPRG
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]