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The map label for this gene is glpD [H]

Identifier: 157960580

GI number: 157960580

Start: 930076

End: 931251

Strand: Direct

Name: glpD [H]

Synonym: Spea_0752

Alternate gene names: 157960580

Gene position: 930076-931251 (Clockwise)

Preceding gene: 157960576

Following gene: 157960581

Centisome position: 17.97

GC content: 50.34

Gene sequence:

>1176_bases
ATGGCGACAGTGGATCTTCTAGTCATAGGCGGGGGCATCAATGGTGCCGGTATTGCCCAGTGCGCGGCAGCCGCGGGCTA
TAGTGTGTTATTGCTTGAGAGAGAGACTATTGCTGGCCAGACTTCCGCCAACTCCAGTAAGCTCATTCATGGTGGGCTGC
GTTATTTAGAGTCAGGCCAACTGCCGTTAGTGAGAAAGTCTCTGGCCGAGCGCAAGGCTCTGCTAAAGCTTGCTCCCAGC
TTAGTTAATCCCATCCCATTCTATATTCCCGTTTATGAAAATAGTCGTCGTAGTCCTTGGGCAATAAGGGCTGGGTTGAG
CCTATATGCCATGCTGAGTGATTTCGATGCCCTTGGGCAATTCAAGTCTGTTCCCTGTGTGAATTGGTCGAAAATTAAAG
GCCTAAAACTCAAAGGCCTCAAGGCGGTGTATCAATATTGGGATGCACAAACCGACGATAAGATGTTGACCCAAGCCGTG
ATTAAGAGTGCGCGCTCACTTGGGGCGGATGTGCTGGAATATGCTCAATGTACCCATATTGAACATCTACAAGGGCACAG
TTTGGTGCGATATCAATATTCATCCATGGAGCAAGAGGTTGAAGCGCTAGCCGTGGTGAATGCCGCTGGACCATGGGTTA
ATCAGGTGCTTGAAACAGTTTCTCCACCGATAGCATCTGTGCCGATAGAGTGGGTGCAGGGCAGCCATCTACTGCTCGAT
ATCCCTGCCAATGACGGCATTCTCTATCTGGAGTCGTGTTTCGACAAGCGGGTAATCTTTGTGATGCCTTGGAAGGGCCG
CACCCTTATTGGCACCACCGAAACATTGTTGTCGTCGCTGGGTAGCCAACCTAAAGTGACGCCGGAAGAGGTGAATTACC
TACTGGGGATCTATAGCCATTACTTTTGCTGCTTTGGTGACGTGGAAGTGTTAAAGACCCGGGTGCTTGATAGCTTTTGC
GGAGTACGAGTATTGCCGAAGCAGGCGGGTAAGGCATTCGATCGCCCAAGAGACACCATACTGAAAATTCAGCCAAGTCA
TCCCAATCTACTCAGCCTATATGGCGGCAAGCTTACGACATACAGAACCACGGCGACTGAAGTGCTCGACTGGTTAGAGG
GCACCATAGGTAAGCGCCAGACCTTGGCTGATTTTGACCAGCTGGTTTTAGATTAA

Upstream 100 bases:

>100_bases
AACCTGCTTGGGCAACGGTAGAGCAGAGTGTAGCGCTCTCAAGCATACAGAGAATTCATTCTAGTGAGAGCAAGGCAAGA
CTCTAATTCAAGGAGCTGAA

Downstream 100 bases:

>100_bases
TTCATATTGAGCGCCATTTTGAGCACTTATTTGAGCAAGTATTTACGTGCTGAATTGACGGTTAAGGTTTCATTAAACTG
TAACCTTAATGTCATACTAT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MATVDLLVIGGGINGAGIAQCAAAAGYSVLLLERETIAGQTSANSSKLIHGGLRYLESGQLPLVRKSLAERKALLKLAPS
LVNPIPFYIPVYENSRRSPWAIRAGLSLYAMLSDFDALGQFKSVPCVNWSKIKGLKLKGLKAVYQYWDAQTDDKMLTQAV
IKSARSLGADVLEYAQCTHIEHLQGHSLVRYQYSSMEQEVEALAVVNAAGPWVNQVLETVSPPIASVPIEWVQGSHLLLD
IPANDGILYLESCFDKRVIFVMPWKGRTLIGTTETLLSSLGSQPKVTPEEVNYLLGIYSHYFCCFGDVEVLKTRVLDSFC
GVRVLPKQAGKAFDRPRDTILKIQPSHPNLLSLYGGKLTTYRTTATEVLDWLEGTIGKRQTLADFDQLVLD

Sequences:

>Translated_391_residues
MATVDLLVIGGGINGAGIAQCAAAAGYSVLLLERETIAGQTSANSSKLIHGGLRYLESGQLPLVRKSLAERKALLKLAPS
LVNPIPFYIPVYENSRRSPWAIRAGLSLYAMLSDFDALGQFKSVPCVNWSKIKGLKLKGLKAVYQYWDAQTDDKMLTQAV
IKSARSLGADVLEYAQCTHIEHLQGHSLVRYQYSSMEQEVEALAVVNAAGPWVNQVLETVSPPIASVPIEWVQGSHLLLD
IPANDGILYLESCFDKRVIFVMPWKGRTLIGTTETLLSSLGSQPKVTPEEVNYLLGIYSHYFCCFGDVEVLKTRVLDSFC
GVRVLPKQAGKAFDRPRDTILKIQPSHPNLLSLYGGKLTTYRTTATEVLDWLEGTIGKRQTLADFDQLVLD
>Mature_390_residues
ATVDLLVIGGGINGAGIAQCAAAAGYSVLLLERETIAGQTSANSSKLIHGGLRYLESGQLPLVRKSLAERKALLKLAPSL
VNPIPFYIPVYENSRRSPWAIRAGLSLYAMLSDFDALGQFKSVPCVNWSKIKGLKLKGLKAVYQYWDAQTDDKMLTQAVI
KSARSLGADVLEYAQCTHIEHLQGHSLVRYQYSSMEQEVEALAVVNAAGPWVNQVLETVSPPIASVPIEWVQGSHLLLDI
PANDGILYLESCFDKRVIFVMPWKGRTLIGTTETLLSSLGSQPKVTPEEVNYLLGIYSHYFCCFGDVEVLKTRVLDSFCG
VRVLPKQAGKAFDRPRDTILKIQPSHPNLLSLYGGKLTTYRTTATEVLDWLEGTIGKRQTLADFDQLVLD

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=395, Percent_Identity=30.126582278481, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI285002231, Length=395, Percent_Identity=30.126582278481, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI2367226, Length=386, Percent_Identity=35.4922279792746, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1788574, Length=379, Percent_Identity=26.1213720316623, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17509253, Length=389, Percent_Identity=30.0771208226221, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI115534726, Length=387, Percent_Identity=29.9741602067183, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322036, Length=396, Percent_Identity=28.5353535353535, Blast_Score=116, Evalue=6e-27,
Organism=Drosophila melanogaster, GI161077125, Length=406, Percent_Identity=31.7733990147783, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24653942, Length=406, Percent_Identity=31.7733990147783, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24653944, Length=406, Percent_Identity=31.7733990147783, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20130025, Length=406, Percent_Identity=31.7733990147783, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24586295, Length=385, Percent_Identity=26.7532467532467, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19921278, Length=399, Percent_Identity=26.5664160401003, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 42988; Mature: 42857

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVDLLVIGGGINGAGIAQCAAAAGYSVLLLERETIAGQTSANSSKLIHGGLRYLESGQ
CCEEEEEEEECCCCCCHHHHHHHHCCCEEEEEECHHHCCCCCCCCCHHHHHHHHHHHCCC
LPLVRKSLAERKALLKLAPSLVNPIPFYIPVYENSRRSPWAIRAGLSLYAMLSDFDALGQ
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHH
FKSVPCVNWSKIKGLKLKGLKAVYQYWDAQTDDKMLTQAVIKSARSLGADVLEYAQCTHI
HCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
EHLQGHSLVRYQYSSMEQEVEALAVVNAAGPWVNQVLETVSPPIASVPIEWVQGSHLLLD
HHHCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHCCCHHHCCCCEEEEE
IPANDGILYLESCFDKRVIFVMPWKGRTLIGTTETLLSSLGSQPKVTPEEVNYLLGIYSH
ECCCCCEEEEEHHHCCCEEEEECCCCCEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHH
YFCCFGDVEVLKTRVLDSFCGVRVLPKQAGKAFDRPRDTILKIQPSHPNLLSLYGGKLTT
HHHHCCCHHHHHHHHHHHHHCCEEEHHHHCHHCCCCCCCEEEEECCCCCEEEECCCEEEE
YRTTATEVLDWLEGTIGKRQTLADFDQLVLD
EECHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ATVDLLVIGGGINGAGIAQCAAAAGYSVLLLERETIAGQTSANSSKLIHGGLRYLESGQ
CEEEEEEEECCCCCCHHHHHHHHCCCEEEEEECHHHCCCCCCCCCHHHHHHHHHHHCCC
LPLVRKSLAERKALLKLAPSLVNPIPFYIPVYENSRRSPWAIRAGLSLYAMLSDFDALGQ
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHH
FKSVPCVNWSKIKGLKLKGLKAVYQYWDAQTDDKMLTQAVIKSARSLGADVLEYAQCTHI
HCCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
EHLQGHSLVRYQYSSMEQEVEALAVVNAAGPWVNQVLETVSPPIASVPIEWVQGSHLLLD
HHHCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHCCCHHHCCCCEEEEE
IPANDGILYLESCFDKRVIFVMPWKGRTLIGTTETLLSSLGSQPKVTPEEVNYLLGIYSH
ECCCCCEEEEEHHHCCCEEEEECCCCCEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHH
YFCCFGDVEVLKTRVLDSFCGVRVLPKQAGKAFDRPRDTILKIQPSHPNLLSLYGGKLTT
HHHHCCCHHHHHHHHHHHHHCCEEEHHHHCHHCCCCCCCEEEEECCCCCEEEECCCEEEE
YRTTATEVLDWLEGTIGKRQTLADFDQLVLD
EECHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]